Anticonvulsants "Topamax": Malangizo ntchito

Kukonzekera "Topamax" malangizo amatanthauza gulu la mankhwala anticonvulsant, amene kanthu walangizidwa kutsekereza zolandilira sodium, kuchotsa spasms ndi Kupha malemeredwe mitsempha. Maziko a mankhwala ndi kuchuluka ntchito γ-aminobutyric acid ndi carbonic anhydrase chopinga ntchito isoenzymes lapansi. Komanso, wothandizila antiepileptic "Topamax" (wosuta kuyenda mu akonzedwa, ndi akutsimikiza) zimathandiza kusinthasintha mawu a mtundu GABAA cholandilira tilinazo. Kugwiritsa ntchito mankhwala pa wodwalayo, n'kuchiumba odana ndi yotupa, analgesic ndi zotsatira antispasmodic.

Mukhozanso mankhwala "Topamax" (wosuta za kumasonyezanso) mu mawonekedwe a makapisozi gelatin, amene ali monga mbali yaikulu kuchuluka kwa topiramate mamiligalamu twente-faifi kapena makumi asanu. Wothandiza zosakaniza ndi mapadi nthochi, shuga ndi povidone granules. The zikuchokera chipolopolo kapisozi monga zipangizo monga ndi sodium lauryl sulphate gelatin, sorbitan monolaureat, madzi, titaniyamu woipa ndi inki.

Mankhwala anticonvulsant "Topamax" malangizo Buku limalangiza makamaka zochizira odwala ndi matenda a "khunyu" kapena "dzina la syndrome Lennox-Gastaut." Komanso dotolo mwachangu mankhwala mankhwala kwa anthu amene amadwala mutu waching'alang'ala, zimandilimbikitsa-clonic, tsankho kapena myoclonic khunyu. Komanso, ndi mankhwala antiepileptic amavutikira amajomba ndipo amatha mu nthawi yochepa kuthetsa spasms minofu.

Tengani makapisozi "Topamax" malangizo ndi mosamalitsa amaletsa anthu ndi hypersensitivity kuti topiramate kapena matupi awo sagwirizana anachita zosakaniza ina ili zikuchokera. Komanso osavomerezeka ndi anticonvulsant kuti akazi adzabala mwana. Mndandanda wa contraindications monga kwambiri ndi mkaka wa m'mawere nthawi, ndi zaka ziwiri. Ndi kusamala kwambiri ayenera kumwa mankhwalawa anthu nefrourolitiazom, kwa chiwindi kapena aimpso insufficiency.

Kanani kulandira mankhwala antiepileptic ayenera odwala hypercalciuria.

Pankhani zotheka zosiyanasiyana chokhwima chikwiyire ntchito mankhwala "Topamax", pano mu malo oyamba, mayiko amenewa ayenera allocated monga chizungulire, chidwi mkhutu, paraesthesia, ulesi, kutopa, irritability ndipo kusinza. Komanso, angagwe utachepa kudya, ulesi, kuwonongeka chidziwitso, gipoesteziya, dysarthria, kugwedeza, disorientation, ndi lability maganizo. Kusapeza m'mimba, gastritis, pakamwa youma, magazi m'kamwa, glossodiniya ndi kudzimbidwa zingachitikenso anthu kutenga makapisozi "Topamax". mankhwala awa akhoza kukhala chifukwa cha kukokana kwa minofu, myalgia kapena arthralgia chitukuko, malungo ndi movutikira.