"Retinol palmitate"

"Retinol palmitate" - mankhwala wa gulu pharmacological mavitamini. Izo ntchito monga zowonjezerazo kwa mankhwala zoyambirira za matenda: opatsirana chikhalidwe (chibayo, chifuwa, tracheitis, kamwazi, chikuku), khungu (hyperkeratosis, frostbite, mabala, zilonda zamoto, chikanga), conjunctivitis, Keratomalacia, retinitis pigmentosa, rickets, kutupikana, mastitis. Komabe, cholinga chachikulu kuchotsa mankhwala hypovitaminosis ndi avitaminosis A. "Retinol Palmitate" amagwiritsidwanso ntchito pa matenda a zotupa zaminyewa ngati leukemias utithandize wothandizira wa hematopoietic minofu kukana kuti zochita za mankhwala osiyanasiyana cytostatic.

Mukhozanso mankhwala mu mafuta njira fomu makapisozi. Waukulu yogwira mankhwala ndi retinol palmitate, kuti zigawo wothandiza monga woyengedwa mafuta mpendadzuwa, nipagin, glycerol, gelatin, madzi oyera.

Izi mankhwala pafupifupi atamezedwa kotheratu pamene anatengedwa pakamwa. Komabe, mu thupi, ndi omangidwa anagawira: pali ndalama zapadera mu diso, chiwindi, ang'onoang'ono - mu mapapo, impso, mtima, lactating zopangitsa mammary, ndi zopangitsa adrenal. metabolites mankhwala ali excreted mu ya ndulu ndi ndowe. Excretion wokongola pang'onopang'ono, kotero kukonzanso kuvomereza kumabweretsa kudzikundikira ndi maonekedwe mavuto.

"Retinol palmitate" ali pharmacodynamics zovuta. Iwo imayendetsa njira redox, mwachindunji kumapangitsa kaphatikizidwe wa pyrimidine ndi purine zapansi, kumatanthauza kupereka njira mphamvu kagayidwe kachakudya (amalenga kwa ATP kaphatikizidwe). Zimenezi zimatheka kuyamika wapadera kapangidwe mankhwala thunthu yogwira imene kapangidwe ali ndi chiwerengero chachikulu cha kumangidwa zimalimbikitsa. The mankhwala kumapangitsa mapangidwe mapuloteni kuti m'pofunika kuti kukula kwa chichereŵechereŵe ndi fupa. Komanso kumathandiza kwambiri keratinization epithelium (hyperkeratosis), kumaonjezera kukaniza matenda. Mothandizidwa ndi thunthu yogwira kumatheka kaphatikizidwe mahomoni adrenal, thyroxine imathetsa liberatiou, amapereka ntchito bwinobwino thukuta ndi zopangitsa sebaceous.

"Retinol palmitate" malangizo amene amafotokoza mwatsatanetsatane zizindikiro zonse, mlingo ndi njira ntchito Komabe, ena contraindications, kudziwa zomwe ndi kupewa zotsatira zapathengo mbali. mankhwala ndikoletsedwa Pa okwera tilinazo munthu, cholelithiasis, aakulu kapamba, mu trimester mimba. Mwa mavuto tisaiwale kuwonongeka kwa chikhalidwe ambiri, anaonetsa mutu, ulesi, kugona, matenda gait, kupweteka mafupa m'munsi nthambi. Zotsatira zina ndi monga nseru, kusanza, malungo, khungu khungu, zizindikiro hypervitaminosis A, totupa pakhungu.

Musanagwiritse ntchito mankhwala ayenera bwinobwino zimene ankachita onse mankhwala zotheka. Oral kulera ndi estrogens kwambiri kumapangitsanso mayamwidwe yogwira kuti zikhoza chitukuko cha hypervitaminosis. Chikuonetseratu corticosteroids ndi mowa amachepetsa zotsatira achire mankhwala. Choncho, nthawi zina ndi bwino kukana kutenga "retinol palmitate." Ndemanga za iye, ngakhale n'zotheka zotsatira zambiri mbali pafupifupi nthawi zonse zabwino. Ichi ndi chifukwa bioavailability mkulu ndi efficacy a mankhwala osakaniza ndi mitengo wotsika pa izo.