"Topiramate": malangizo ntchito, migraine yeniyeni, analogs

Matenda ya ubongo zoipa bwanji magwiridwe a chamoyo wonse. Mwachitsanzo, ngati matenda zotere khunyu, munthu amalandira moyo chilema. Mwachibadwa, kudwala imeneyi nthawi zonse nkhondo kuchepetsa kufala kapena kuteteza mawonetseredwe kuukira. Kukonzekera "topiramate", malangizo ntchito a umene wanenedwa hereinafter, monga mankhwala kudwala izi. Komanso, angagwiritsidwe ntchito amalimbana ndi matenda ena. mankhwala cholinga ntchito nthawi yayitali.

General ikulongosola za kukonzekera ndi zikuchokera

"Topiramate", malangizo ntchito amene ayenera mosamala anafotokoza kuti wodwala, ndi wothandizila antiepileptic ponena za mpumulo ndi kupewa khunyu. Nthawi zambiri mankhwala opangidwa mu mawonekedwe a miyala, mkati limene pali ufa woyera. Mapilitsi mu mapaketi chithuza a lalanje. Mu mmodzi wa iwo akhoza muli 25 kapena 10 mg wa yogwira pophika - topiramate. Komanso, mankhwala umalowa dihydrate kashiamu wa phosphate wa hydrogen, magnesium stearate, wowuma, katundu mankhwala enaake a hydroxycarbonate. thunthu mwina ndigwire ntchito ya nyemba sekondale ndi kuteteza khunyu.

Pambuyo wodwalayo kutenga mankhwala, izo mofulumira kwambiri odzipereka mu m'mimba ndipo matumbo. Ndi mapuloteni magazi yaikulu yogwira pophika amangidwa ndi% 13-17 yekha. Nambala pazipita topiramate mu magazi anaona pambuyo Mphindi 120. Excretion mankhwala ndi metabolites ake amapangidwa makamaka mu mkodzo. Theka moyo maola 21. Ngakhale nthawi imeneyi akhoza ziwonjezeke vuto la mavuto ndi chiwindi ndi impso.

zikuonetsa

Ngati inu aikidwa ngati mankhwala "Topiramate" malangizo Buku limanena za zizindikiro izi:

• Khunyu chikwiyire syndrome Lennox-Gastaut (monga akuthandiza wothandizila).
• The tsankho kapena zowombetsa mkota zimandilimbikitsa-clonic khunyu (monotherapy).
• Khunyu ana kwa zaka 3 ndi akulu (kuika choyamba).
• Pakuti kupewa migraine akuluakulu.
• Neuropathy.
• Post-kusokonezeka maganizo.
• Mowa Syndrome.
• Wosangalala monyanyira-kuvutika maganizo mawonekedwe.
• Maganizo matenda.

Mankhwalawa amatha matenda wosangalala. Monga mukuonera, "topiramate", malangizo ntchito amene nthawi zonse mu phukusi ndi mankhwala, ali osiyanasiyana ka ntchito. Komabe, ngakhale mu milandu m'pofunika kukhala osamala ndi phwando lake, monga mankhwala imatengedwa amphamvu.

Contraindications ndi zofooka za kugwiritsa ntchito

Ngakhale mphamvu ya chida ichi, ali osavomerezeka zina. Pakati contraindications akhoza kuzindikiridwa motere:

• zaka ana (zaka 2). The mankhwala ndi amphamvu kwambiri kwa thupi mwanayo.
• Kusagwirizana zikutanthauza kapena zigawo zake.
• Pa mimba ndi mkaka wa m'mawere. Waukulu yogwira pophika akhoza mkatikati mwa zonse zopinga mu mkaka wa m'mawere.
• Chizolowezi kupanga miyala impso.
• Aakulu njira yotupa mu thupi, aakulu aakulu pathologies.

Kupatsa mankhwala "topiramate" migraine, dokotala ayenera kukhala makamaka tcheru kuti odwala amene ali ndi mavuto ndi impso ntchito ndi chiwindi. Kukhazikitsa galimoto m'thupi Pankhaniyi ndi liwiro, kotero mavuto osayembekezereka zingachitike.

Kodi mankhwala kumachitika?

Ngati inu aikidwa mankhwala "topiramate", malangizo amapereka maonekedwe a zochita chowawa:

• Chizungulire, mutu, kulephera kuwona, kulankhula matenda, kuchuluka mantha. Zingaoneke psychomotor retardation, kutopa, amalephera kumvetsera.
• Somnolence, maganizo lability, maganizo.
• Nthawi zina, kukumbukira yochepa imfa, chisokonezo cha chikumbu, chosokoneza cha zotengeka kukoma.
• Kunyansidwa ndi kusanza.
• Chiwindi kulephera.
• Non-matenda a chiwindi.
• kuwonda.
• ululu m'mimba.
• Kuzizira.
• Nthawi zina angadwale kutentha.
• Popeza kusamba, epistaxis, kutsitsa leukocytes magazi.
• Nthawi zina kwambiri, kuyerekezera zinthu m'maganizo angagwe.
• Yafupika zithunzi acuity, ndi kuphwanya galimoto ntchito ya zaka (amasuntha zokha). Koma pangakhale kutukusira kwa conjunctiva lapansi.
• Kutupa usinini.
• Dryness pakamwa.
• Utachepa libido amuna ndi akazi. Akale akhoza ngakhale kuukira kusabala.
• Gastritis ndi chapamimba chilonda.
• Kutsekula m'mimba kapena kudzimbidwa.
• Halitosis.
• Minofu ululu, kufooka.
• Phokoso kapena akamaganizira, ndipo nthawi zina kumva imfa.
• Kulakwila kulemba ndi kuwerenga ana.
• dzanzi wa malekezero.
• Liwiro kukula ana, kufooketsa mphamvu fupa.
• thupi lawo siligwirizana ndi kuwonetseredwa pa khungu: kuyabwa zidzolo, zilonda.

Monga mukuonera, mankhwala "Topiramate" migraine komanso kutenga mosamala kwambiri. Makamaka wolemera ndi ana. Choncho, tiyenera mosamalitsa kutsatira mlingo. Pankhaniyi, onse madokotala ndiponso makolo ayenera nthawi zonse kuyan'ana mkhalidwe wa mwanayo.

Features mlingo ndi ntchito

Adzaika anasonyezedwa mankhwala zitha kukhala dokotala. Self-kuyamba phwando ake n'zosathekadi, monga pali kuthekera kwa kuwonongeka. Komanso, mankhwala amagulitsidwa ndi mankhwala.

Ngati mwakhala Kwalamulidwa njira "Topiramate" malangizo amapereka wambiri ake m'kamwa, kaya mawonekedwe a kumasulidwa. Imwani mankhwala akhoza kugawidwa ndi chakudya, makamaka chifukwa sikumangotikhudza kanthu miyala. Ndi zofunika kuti apange mankhwala pa nthawi yomweyo. Musagwiritse kutafuna kapena osokoneza mankhwala, popeza kulawa zowawa. Komanso, akupera mankhwala kungam'lepheretse Mwachangu ake.

Ikani chuma ayenera kukhala motere:

• Ngati "topiramate" miyala ndi mbali ya Integrated mankhwala anticonvulsant, mlingo tsiku la mankhwala akhoza osiyanasiyana monga 200-400 mg. mlingo Izi kawirikawiri ogaŵikana Mlingo 2. Ndi bwino kuyamba mankhwala ndi Mlingo otsika (25-50 mg), amene anatengedwa masiku 7 tsiku lililonse. Komanso, mlingo pang'ono ndi pang'ono ziwonjezeke kwa 25 kapena 50 mg pa sabata kapena awiri mpaka kuchuluka akadakwanitsira, akulamulira ndi zotsatira zabwino. Makhwalawa mu nkhani iyi, kawiri pa tsiku. The pazipita mlingo odwala wamkulu zingatenge tsiku, 1600 mg.
• Ngati dokotala wanu wadzikakamiza mwana zaka zoposa 2 "topiramate", kugwiritsa ntchito mankhwala opangidwa ndi chiwembu zotsatirazi: kuyamba kumwa mankhwala ayenera mlingo wa 25 mg kawiri pa tsiku. Chiwerengero cha tsiku lokonzekera patsiku ndi 5-9 mg / kg pa thupi. Ndi bwino kugwiritsa ntchito mankhwala madzulo, pamaso yogona, kuchepetsa chiopsezo cha mavuto. Njira yoyamba ya mankhwala masiku 7. Ngati ndi kotheka, mlingo kwa mlungu umodzi kapena iwiri kumawonjezera ndi 1-3 mg / kg. Chikuonetseratu lagawidwa nthawi 2.
• Ngati mankhwala ntchito monotherapy, dokotala ayenera kusonyeza chidwi mtima. Iye ayenera kulamulira pafupipafupi maonekedwe a khunyu pambuyo kuchotsa anticonvulsant mankhwala ena. Ayenera kuyamba kutenga osachepera kuchuluka mg ndi 25 patsiku kamodzi pa tsiku. Komanso, mlingo akhoza chinawonjezeka, koma zachitika pang'onopang'ono masabata 1-2.
• Ngati wodwala sadzalekerera mankhwala amenewa, mwamphamvu yake kuchepetsedwa kapena kutambasula imeneyi kuonjezera mitengo kulandiridwa.

Kwa mlingo kulanda si kuchuluka, m'pofunika kuti agwire chiyembekezo chakuti mankhwala pang'onopang'ono. Mlungu uliwonse mlingo wa mankhwala yafupika ndi 100 mg.

ambiri osokoneza

Ngati mwapatsidwa njira "Topiramate" malangizo ntchito (inu analogs nkhani zotsatirazi) apo pofuna kupewa mavuto chifukwa Mlingo kwambiri mankhwala. Komabe, pali nthawi zina pamene wodwala chifukwa ena amatenga mankhwala opitirira muyeso. Ndiye akhoza kubwera ndi ambiri osokoneza.

Iwo amakhala ndi khunyu kuchuluka, maonekedwe kugonagona, masomphenya mkhutu, kugwirizana ndi maganizo. chingachitike mbali ya mankhwala osokoneza bongo akhoza nakweza. Mwachibadwa, mu nkhani iyi m'pofunika kukhwimitsa mwamsanga kuthandiza kupewa wambirimbiri zinthu mu makope zokhudza zonse.

Choyamba, muyenera itanani ambulansi. Komanso, ndondomeko imagwiridwa chapamimba lavage. Komanso, wodwala ayenera kutenga mankhwala absorbent "Enterosgel" adamulowetsa mpweya. Ngati malo wolemera kwambiri, wodwalayo mwamsanga m'chipatala. Kochotsa mankhwala magazi ndi hemodialysis ndondomeko limagwirira ntchito.

Features wa mogwirizana ndi mankhwala ena

Ngati muyenera "Topiramate" malangizo Buku (ofanana matanthauzo akhoza kukhala ndi cholinga chofanana pa thupi) limanena kuti sikugwirizana ndi mankhwala onse. Mwachitsanzo, akhoza pamodzi valproic asidi "pentobarbital", "Carbamazepine". Mankhwalawa ukunenedwa zochizira matenda mantha. Olowa phwando kuganizira anapatsidwa si maganizo awo mu madzi a m'magazi. Komabe, mlingo "topiramate" zikhoza kuchepetsedwa. Mulimonsemo, poika mankhwala zochizira kuphatikiza, mlingo wa njira zonse zofunikira kuti n'zoyenera kusintha.

Ngati dokotala wanu waganiza mankhwala mankhwala anapereka molumikizana ndi "pioglitazone", m'pofunika kuti aziona wodwalayo alili matenda ashuga. Mwa kaphatikizidwe "Topiramate" ndi "metformin" Mwina kusokoneza zimam'patsa kagayidwe mu thupi. Co-ka anati mankhwala ndi "acetazolamide" ndi analogues ake kumaonjezera ngozi ya miyala impso.

Taganizirani mfundo imene kuti ayeretse thupi la mankhwala ndi metabolites ake amatenga masiku angapo. Mu anthu ndi ntchito mkhutu aimpso, nthawi imeneyi akhoza ziwonjezeke kawiri. M'pofunika kudziwa, monga m'pofunika kusintha mlingo. Mlingo wa mankhwala a dokotala amawerengedwa pa nkhani iliyonse payekha.

Kusamala

Ngati muli ndi ntchito "Topiramate" mapiritsi (malangizo ntchito ndi chikalata waukulu akulamulira mankhwala) ayenera atamwa mogwirizana ndi malangizo a dokotala nawo. Komabe, pali ena malangizo apadera kuti Tisanyalanyaze:

• Mu nkhani ya achire sangakhoze kuchita izo mwadzidzidzi. Mfundo yakuti pali kuthekera kuti pafupipafupi ndi mphamvu ya khunyu kuonjezera. Choncho, kuchepetsa malamulo a mankhwala zizichitidwa pang'onopang'ono.
• Mwa zina, mbali ya mankhwala kungakhale anorexia, imbaenda wamphamvu zikutha m'mayiko thupi chifukwa kuwonda. Popewa izi, chonde kukaonana ndi kadyedwe ndi. zakudya ayenera kusintha kuti thupi amalandira zonse mavitamini zofunika ndi mchere ntchito moyenera.
• Pa mankhwala sayenera kudyedwa mankhwala psychoactive ndi mowa.
• Medicine "topiramate" (malangizo, maganizo, ndi pamaso pa anzawo ndi zofunika kwambiri kwa mtima) ali ndi mphamvu pa mlingo anachita, choncho kuyendetsa galimoto kapena ntchito makina ovuta pa mankhwala sayenera.
• Mapiritsi sayenera kuperekedwa kwa ana osakwana zaka 2 hletnego.
• Iwo ayenera kukhala osamala odwala anthu amene pali kuphwanya magwiridwe impso ndi chiwindi.
• Ngati inu kuiwala kutenga piritsi mosamalitsa nthawi, yesani kumwa pamene inu mukukumbukira. Komabe, ngati muli ndi nthawi itafika kuti chikuonetseratu lotsatira, chifukwa nsomba mmwamba sayenera kutenga muyezo awiri. Ndi bwino kupitiriza kumwa mankhwala a dongosolo kutchula.
• zolondola zokhudza kanthu mutagenic mankhwala pa thupi ayi. Komabe, kuphunzira mankhwala mbewa chikwiyire maonekedwe a zotupa a chikhodzodzo. Komabe, zimenezi zachitika owonjezera mlingo analola, ndipo nthawi zina.

kusamala

Ngati inu kutenga mankhwala "Topiramate" malangizo Buku (ndemanga za mankhwala amaphunzira kenako) zikusonyeza ena kusamalitsa kuti ayenera kukumana pofuna kupewa yatsoka mosiyanasiyana chowawa:

• Ngati wodwala pa dialysis, kukonzekera kuchitapo kanthu zothandiza ayenera akulu theka la mlingo tsiku pamaso ndondomeko kuyeretsedwa magazi kenako.
• Pa achire mankhwala ayenera kuwonjezera kadyedwe madzimadzi. Izi kuteteza mafunsidwe a miyala impso.
• Ngati pali lalikulu kuwonda, n'zotheka kusintha zakudya ndi kuwonjezera zowonjezera zakudya zimene zimalimbikitsa mayamwidwe wa zakudya.
• Undesirably pamodzi ndi "topiramate" kulandira zinthu zoyambitsa chapakati mantha dongosolo maganizo.

Monga mukuonera, mankhwala ndi lalikulu kwambiri, choncho muyenera musalankhule medicate, chifukwa inu mukhoza kupanga zinthu.

NKHANI yosungirako, analogs ndi ndemanga

Ngati muli ankaimira mwa abwino, mukhoza kufunsa za analogs mankhwala monga "topiramate". "Topamax" malangizo ntchito omwe ndi ofanana kwambiri malongosoledwe yapita, ndi m`modzi wa iwo. Iwo ali yemweyo yogwira pophika. Pali mankhwala ena analogues "Topsaver", "Toreal", "Maksitopir". Basi anazimitsa pa, mankhwala sindingakhoze. Mwina iwo sudzapereka ndi zotsatira zabwino, chifukwa zikuchokera awo osiyanasiyana. Musanayambe kumwa mankhwala anapereka ayenera kukaonana ndi dokotala. Makamaka popanda mankhwala awo ndi chodziwikiratu wina adzalemba.

Khalani mankhwala ayenera kukhala mu mdima kumene mkatikati cheza pang'ono kuwala, chinyezi. Musamakhulupirire thunthu kuchokera magwero kutentha. Chitsimikizo nthawi ya n'loonadi ndi zaka 2. Patapita nthawi ino, mankhwala ayenera kutayidwa. Ndipo izi ziyenera kuchitika kotero kuti iwo sakanakhoza kufika ana.

Koma ndemanga, iwo ndi osiyana. Odwala onani Mwachangu mkulu wa mankhwala mu ulamuliro wa khunyu. Iye ndi wabwino kwambiri kwa mutu waching'alang'ala. Komabe, wothandizila ali ndi ndalama zambiri mkulu. Mwachitsanzo, mtengo wa phukusi munthu angakhale 600 rubles ndi zambiri. Ngati zili zolondola kugwiritsa ntchito mankhwala, ndi bwino kukwaniritsa yaitali chikhululukiro. Ngakhale kuti pali maganizo ena. Mwachitsanzo, zina, ana makutu kukumbukira kwambiri, kakulidwe yomweyo, ndi munthu mankhwala si kuthandiza. Palinso kuwonongeka boma la impso.

Tikumbukenso kuti m'madera ena a dziko umaimiridwa ndi mankhwala ndi kupezeka pa mankhwala-free, nkhani kuti osaphatikizidwamo ena. Koma musanayambe kugula chida, muyenera kukaonana ndi dokotala amene adzakupatsani chilolezo. Kumbukirani, kudzikonda zinadzala ndi mavuto aakulu. Takambiranazi zotsatira za chiphunzitso monga "topiramate", malangizo, ndemanga kupweteka kwa mutu ndi zina zambiri. Dotolo ndi kukhala wathanzi!