"Alfacalcidol": malangizo ntchito, amasulidwe mawonekedwe, ndemanga, photos, mlingo analogs

Losowa vitamini D3 chifukwa mavuto aakulu. Ana kuchepekedwa izi zinadzala ndi chitukuko cha rickets, pamene akuluakulu chikhoza kukhala kupanda chifukwa cha kufooka kwa mafupa ndi mavuto ofanana.

Msika wamakono of Medicine amapereka makasitomala ake osiyanasiyana mankhwala kuthetsa akusowa vitamini imeneyi. mankhwala china "Alfacalcidol." Malangizo ntchito amadziwika kuti ndi njira ina yabwino matenda bwino vitamini-mchere.

pharmacodynamics

medicament Ichi ndi vitamini D3 yogwira mawonekedwe. The lamulo nzeru mankhwala ofunika mchere, monga phosphorous ndi calcium, ndi mbali yofunika ya mankhwala "Alfacalcidol." Ntchito ya mankhwala othandiza mu zolimbikitsa fupa mapangidwe. Mu okhudzidwa ake mwachindunji kuchuluka mayamwidwe kashiamu ndi phosphorous mu intestine ndi impso. Komanso, mankhwala kumawonjezera fupa mchere kachulukidwe ndi pa nthawi yomweyo kuchepetsa mlingo wa zili mu PTH magazi. Motero, "Alfacalcidol" ali antirahitichnoe amadza ndi kumathandiza kuchepetsa chiwerengero cha fractures.

Ngati mankhwala ndi maphunziro, ndiye muulamuliro wake bwino kuyenda, yafupika fupa ndi ululu minofu (ndizo zotsatira za kuswa kagayidwe kashiamu-phosphorous).

Nthawi zina, wolungamitsidwa ntchito mankhwala?

"Alfakltsidol" malangizo ntchito ndi malangizo a madokotala analimbikitsa mankhwala pa nthawi imene mbiri zokhudza osteodystrophy, aakulu aimpso kulephera siteji. Ndiponso, ntchito hypoparathyroidism. Chifukwa ndi cholinga rickets, osteomalacia (kuchepetsa voliyumu ya minofu fupa) ndi fupa olimbikitsa, chikhalidwe cha omwe angakhale osiyana kwambiri. Kufooka kwa mafupa - steroid, senile, postmenopausal - komanso bwinobwino ankachitira ndi "Alfacalcidol" njira.

Mchitidwe woika mankhwala pa nthawi imene wodwala akudwala acidosis aimpso, kapena mbiriyakale ya izo ali Fanconi matenda (matenda zovuta, kuphatikizapo acidosis aimpso atasenza cholowa, nephrocalcinosis, rickets ndi matenda mwina hypophyseal).

Ndi mavuto onsewa, "Alfacalcidol" angapereke thandizo ogwira.

Pamene sayenera kulandira?

Mndandanda wa contraindications kuti mankhwala lili "Alfacalcidol" malangizo Buku. akatswiri Reviews lesa kutenga mankhwala ndi mbiri ya mudziwe hypercalcemia, hyperphosphatemia (kupatula pamene kukula hyperparathyroidism), gipermagnemii. Musagwiritse ntchito mankhwala ngati kuledzera a chamoyo kugwirizana ndi okhutira kwambiri vitamini D3. Ndi zosavomerezeka Ndinapereka "Alfacalcidol" mums unamwino.

Chabwino, dala kunena, inu simungakhoze kutenga mankhwala kwa anthu ndi hypersensitivity munthuyo zigawo mankhwala.

Mapulogalamu ndi mlingo

Mfundo yonse pa momwe ntchito ndipo lili dosing kwa mankhwala "Alfacalcidol" malangizo Buku. Mankhwala mawonekedwe (makapisozi a 0,25 mg kapena 1), mlingo ndi nthawi ya achire Inde dokotala anasankha payekha malinga ndi kukula kwa alili ndi chikhalidwe cha matenda.

Mwachitsanzo, odwala wamkulu ndi rickets, chifukwa cha kuperewera kwa vitamini D3, mavuto ndi kapepala kakuti m'mimba, ayenera kulandira kwa tsiku mu kuchuluka mlingo wa mg wa 1 ndi 3. A zabwino ndi amalimbikitsa hypoparathyroidism gonjerani ku mg wa 2 mpaka 4 wa mankhwala patsiku. Daily buku pa kulephera ndi aimpso ntchito osteodystrophy sayenera upambana kuchuluka kwa medicament 2 microgram. Fanconi syndrome ndi acidosis aimpso bwino nkhani kuchitiridwa "alfacalcidol" mtima kulandira mlingo tsiku mu buku la 2.6 micrograms. Mu kukhalapo kwa odwala ndi rickets hypophosphatemic ndi osteomalacia ogwira tsiku mlingo kuchuluka akhoza osiyanasiyana monga micrograms 4 20.

Madokotala amalangiza kuyambira mankhwala ndi mlingo wotsikitsitsa, yeniyeni aliyense matenda makamaka. chithandizo ayenera kuunikira mu madzi a zinthu monga kashiamu ndi phosphorous (osachepera 1 nthawi sabata). Mlingo "alfacalcidol" chovomerezeka kuwonjezeka ayi micrograms oposa 0.5 patsiku. Pamene osachepera mlingo ogwira chikupezeka, zili kashiamu mu magazi ayenera osati zochepa kulamulira kuposa aliyense masabata 3-5.

zotsatira osafunika

Monga mankhwala ena aliwonse, pali mndandanda wa zotsatira zoyipa ndipo limatanthauza 'Alfacalcidol. " Malangizo ntchito (chimodzimodzi, poyamba, komanso ndi cholinga chofanana) kumabweretsa kuti chidwi cha odwala amene mankhwala akhoza kutani kuti dongosolo m'mimba. Nthawi zambiri, nseru, kusanza, kupweteka epigastric, kudzimbidwa kapena m'mimba, kutentha, kumverera kwa dryness wa nembanemba mucous pakamwa. Akhoza kuoneka matenda a anorexia.

CNS mavuto kumachitika kufooka ambiri ndipo kusinza, kutopa, kupweteka kwa mutu ndi chizungulire. Nthawi zina odwala kunena za chitukuko cha tachycardia (mofulumira kugunda kwa mtima) ndi kuwonjezeka mu magazi. zochita Dermatologic kumachitika monga kuyabwa ndi totupa pakhungu, osati tima kwambiri chitukuko cha mafupa, minofu ndi zowawa olowa. Mwina mosiyana mfundo zasayansi kwa kwambiri mkulu-kachulukidwe lipoproteins. Pali kuthekera kwa hypercalcemia, hyperphosphatemia (amene akudwala kuvutika mu ntchito kwa impso).

Mlingo Kugwiritsa

chiwerengero A zodabwitsa zoipa udzachitika kukachitika kuti kuposa chovomerezeka kwa mankhwala "Alfacalcidol" mlingo. Malangizo ntchito akuchenjeza odwala za chiopsezo kukhala hypervitaminosis D. Zizindikiro zoyambirira ambiri osokoneza chifukwa cha hypercalcemia. Kuyambira yapadera yowala zotheka m'mimba zochita chilichonse, kupweteka kwa minofu, ndi zachitsulo kukoma pa kamwa, kutopa.

Mu kuledzera aakulu odwala lipoti kugona ndi mutu kumachitika kufooka, irritability, kusowa tulo, kuwonongeka zinthu, ndiponso kuchuluka pang'ono magazi. Mu zikuchokera magazi nthawi zina muli ndalama yotsalira ya asafe ndi creatinine. Pali chiopsezo hyperemia conjunctival, calcification a impso, m'mapapo, zofewa minofu ndi magazi zotengera, mapangidwe a concretions mu impso. Pangakhale mavuto ndi mawu (hoarseness).

Kuthetsa zotsatira za ambiri osokoneza mankhwala ayenera kuchotsedwa, m'mimba wosambitsa, perekani, malingana ndi zizindikiro za okodzetsa kuzungulira, bisfofonaty, hemodialysis ntchito njira otsika anaikira a calcium.

Pochita mankhwala

Pali matenda amene m'pofunika kusamalira "Alfacalcidol." Malangizo ntchito analimbikitsa mosamala kuchitira mkhalidwe wawo wa thanzi odwala matenda atherosclerosis, sarcoidosis (kapena mitundu granulomatosis), TB m'mapapo mwanga (siteji yogwira), kulephera mtima ndi aimpso insufficiency ntchito (mawonekedwe aakulu). Chenjerani tisonyezeni "Alfacalcidol" Ngati wodwala zizindikiro nefrourolitiaza. Ana ndi odwala okalamba komanso ali pa chiopsezo (mankhwala yamasika akhoza kutsogolera chitukuko cha atherosclerosis).

Mimba ndi mkaka wa m'mawere

Monga kwa amayi apakati ndi amayi okalamba, ndi "Alfacalcidol" malangizo amalola ntchito kokha pa nthawi imene kuyembekezera zotsatira zabwino kwa mayi n'kosangalatsa thanzi la mwanayo ndi chitukuko.

Hypercalcemia mu mayi woyembekezera, chikwiyire ndi ntchito nthawi yaitali "alfacalcidol," angapereke Kankhani kuti chitukuko cha nambala ya mavuto mwana wosabadwayo. Mwa matenda aakulu kwambiri mwana wosabadwa angatchedwe hypersensitivity kwa vitamini D, kupondereza ntchito kwa England parathyroid, kung'ambika stenosis, retardation maganizo, yeniyeni elfopodobnoy kunja syndrome.

Komanso, "Alfacalcidol" mu mabuku ang'ono angathe pa mkaka wa m'mawere excreted mu mkaka wa m'mawere. Kupewa ngozi ya zizindikiro hypercalcemia mwana, m'pofunika mwadongosolo kutenga mankhwala mosamala.

Mogwirizana ndi zinthu zina

"Alfacalcidol" wogwiritsa Phunziro pankhaniyi tikulimbikitsidwa kuti asalandire zikufanana ndi anticonvulsant (barbiturates, phenytoin, ndi zina zotero. D.) Polingalira za kuwonjezeka wake ( 'alfacalcidol ") kagayidwe. Zotsutsana chikoka zoletsa. Ntchito ya medicament molumikizana ndi wothandizila munali digitalis, kungakhale chitukuko cha arrhythmias.

N'zochititsa chidwi amachepetsa mayamwidwe "alfacalcidol" mu kufanana kwa chikuonetseratu yake albumin, Mankhwalawa ayenera kumwedwa, mafuta mchere, colestipol, colestyramine, sucralfate.

Kuphatikiza Mankhwalawa mankhwala enaake a munali kapena Mankhwalawa ayenera kumwedwa, kumachititsa wa gipermagniemii kapena giperalyuminemii. Posonyeza "alfacalcidol" mankhwala, Ndikukhala ake zikuchokera vitamini D kapena aliyense wa ofanana nawo, kumaonjezera ngozi ya hypercalcemia.

Zotsatira poizoni "alfacalcidol" ali yafupika limodzi ndi izo ntchito tocopherol, asidi ascorbic acid pantothenic, thiamin, riboflavin, vitamini A. Zotsatira kukhudzana "alfacalcidol" sichidziwika kutchulidwa mu kukhalapo kwa ena ofanana ndi etindronoy asidi pamidronic, glucocorticoids, kaltsitona. Komanso, mankhwala kumapangitsa mayamwidwe zipangizo phosphorous munali, amene kumaonjezera ngozi ya osauka hyperphosphatemia.

mankhwala ofanana

m'zinenero mankhwala "Alfacalcidol" analogues mu msika mankhwala a dziko. Malangizo ntchito kakunena pa anthu yabwino kwambiri. Zikuphatikizapo mankhwala "Etalfa", "Alpha-D3 Teva", "Ca-Alfadol", "alfa-Wang", "Oksidevit", "Tevabon".

mankhwala opanga izi kupereka ogula mu zosiyanasiyana: mapiritsi ndi makapisozi gelatin, akutsikira ndi ufa, njira kwa kulowetsedwa mtsempha.

Reviews kukonzekera "Alfacalcidol"

mankhwala aliwonse ali mbali ndi adani, monga momwe zilili ndi lokonzekera "Alfacalcidol." Malangizo ntchito, zithunzi cha odwala amene ali ndi chikoka ankachititsa pa thupi, kuonetseratu kwa ogula kuti mankhwala akhoza kwambiri kusintha khalidwe la munthu wa moyo ndi chiwerengero cha matenda kugwirizana ndi akusowa mavitamini ndi mchere, kagayidwe kashiamu-phosphorous. Komanso, "Alfacalcidol" akhoza kungoyankha kusintha tsitsi ndi misomali, ndiwo kumathandizanso.

Odwala ena sakusangalala ndi mfundo yakuti "Alfacalcidol" sangazigule pa msika lotseguka, monga pamafunika mankhwala kwa dokotala. Komabe, zachipatala ndi a maganizo kukonzekera akuluakulu, ndipo sayenera mosavuta aliyense.