Medicine "Tamoxifen" malangizo pa ntchito chikukhudza gulu la mankhwala antineoplastic ndi zotsatira nonsteroidal ndi antiestrogenic. Kugwiritsa wothandizila ichi kumapangitsa amasulidwe mahomoni pituitary, kumachepetsa kutupa ndi bwino suspends chitukuko cha neoplasms. Kuyambira ndi woyamba kulandira midadada mankhwala kanthu timafunika kwa masabata angapo, popanda kuchititsa zotsatira osafunika zimapezeka ndi overgrowth minofu. Odwala wamwamuna akudwala matenda umuna, kugwiritsa ntchito "Tamoxifen" imfayo kuwonjezeka woipa plasma testosterone. Ngati ife tione pharmacokinetics wa wothandizila odana ndi chotupa, iwo amayamba kugwira ntchito pambuyo pa mphindi makumi atatu pambuyo makonzedwe kufika n'kumene maola awiri.
Mukhozanso mankhwala "Tamoxifen" mu piritsi mawonekedwe chikasu, okhala ndi mbali yaikulu mamiligalamu khumi, makumi awiri, makumi atatu kapena makumi anai tamoxifen citrate. zosakaniza zina: mapadi, wowuma ndi sodium, magnesium stearate, lactose ndi povidone. Chipolopolo lili zikuchokera polyethylene glycol ake, titaniyamu woipa ndi hypromellose. Komanso, pang'ono lactose pano mu mankhwala.
Perekani mapiritsi "Tamoxifen" malangizo Buku akuonetsa kuti odwala endometrial khansa, Prostate kapena mazira, ndi thoracic zopangitsa mammary. Komanso, mankhwala amenewa ndi othandiza kwambiri zotupa mu impso kapena khansa. Sarcoma ndi ofanana ndi kuyamba kutenga mankhwala "tamoxifen". Malangizo ntchito zolemba ndi zotsatira zabwino ntchito pa matenda a etiologies zosiyanasiyana uzlovidnyh formations.
Tengani izi wothandizila antitumor ndi koletsedwa zinachitikira tsankho munthu wa tamoxifen citrate kapena zigawo ina ya mankhwala. Leukopenia, thrombophlebitis, mimba, mkaka wa m'mawere nthawi, maso ndi mitundu choopsa cha matenda a mtima komanso ndi contraindications kuti mankhwala, "Tamoxifen" - malangizo ntchito amamvetsera izo. Komanso, musamwenso odwala kwa chiwindi kapena aimpso insufficiency. Ndi changu chisamaliro anaika mapiritsi "Tamoxifen" ndi thrombocytosis, thrombocytopenia, matenda a ubongo, kapena hypercalcemia.
Izi mankhwala mu magulu ena odwala zingachititse kudzimbidwa, nseru, kusanza, cholestasis, utachepa kudya, kutsegula m'mimba, ndi kusalola chiwindi. Chisokonezo, thrombocytopenia, mutu, leukopenia, kugona, malungo ndi chizungulire zingachitikenso chifukwa cha kutenga mankhwala, "Tamoxifen". Zotsatira zake zoyipa monga, ndi chiopsezo cha magazi uterine, moto ndi kuyabwa mu ziwalo zoberekera, zotupa enaake, urticaria, dermatitis ndi bronchospasm. Kuwonjezera zingakhale ananena kuchepa potency, kumaliseche ukazi, zotupa pa khungu ndi redness.