"Asparkam": analogues, malangizo ntchito

Medicaments malamulo njira kagayidwe kachakudya wa chamoyo, ndi gulu osiyana mankhwala amagwiritsidwa ntchito pofuna kuchiza mitundu yonse ya matenda. Ndipo tiyeni mawuwa sizikuwoneka yosokoneza ndi tanthauzo, izo nzoona. matenda alionse, aliyense ndondomeko pathological chimene chimachitika m'thupi lathu, limodzi ndi kuphwanya njira kagayidwe kachakudya pa mlingo ma. Ndipo kuti awongolera matenda kagayidwe kachakudya mu unyinji kumabweretsa kuchira. Mmodzi wa mankhwala ntchito kuwukonza matenda anati mu thupi "Asparkam". Iwo zinafotokozedwa pathologies ambiri. Tiyeni tione "Asparkam" analogues wa mankhwala ntchito lero.

Pharmacological mapangidwe a "Asparkama"

Monga tanenera kale, ntchito yokonza "Asparkam" amatanthauza gulu la mankhwala okhudza njira kagayidwe kachakudya za thupi. Limagwirira cha zochita za mankhwala zachokera mfundo zotsatirazi.

Wotchuka mfundo zofunika kwambiri pa zonse za okhudza maselo ambiri amaayoni zikuchokera a sing'anga. chidwi linaperekedwa kwa njira ya kagayidwe khungu la potaziyamu ndi magnesium ayoni. Chifukwa cha luso otchedwa asparginatov (a mbali ya mankhwala) nawo okhudza maselo ambiri ion zoyendera kayendetsedwe "Asparkama" kumathandiza kuwonjezeka mu maganizo awo ndi kusintha kagayidwe selo.

Chifukwa thupi chachikulu ndi woonda kumva ndi vutoli wa ayoni (makamaka ayoni potaziyamu), mtima, "Asparkam" akusonyeza zotsatira cardioprotective kuchotsa ndi ion vutoli mu cardiomyocytes. Zimenezi tasonyeza kuchepa excitability ndi conduction njira, kumene munthu amasonyeza mwa zotsatira antiarrhythmic mankhwala.

Kudzera chikoka zomwe zili "Asparkam" mankhwala enaake a ayoni amakhudza ma mpope ndi sodium-potassium kuchepetsa ndende ya vnutriklutochnuyu soda ndi njira zikuthandiza repolarization wa khungu nembanemba. Kuwonjezeka mu kuthekera Kakhungu kumabweretsa mfundo yakuti kuchuluka kochepa wa ayoni kashiamu mu cytoplasm ali nawo ndondomeko za electromechanical lumikiza akitini ndi myosin cardiomyocytes.

Asparginat Komanso, mbali ya mankhwala, amalimbikitsa kutsegula njira kagayidwe kachakudya, kumaonjezera osati kwa amino asidi kaphatikizidwe, komanso kaphatikizidwe wa dzuwa kwa amino ndi lipids, nawo lamulo la kagayidwe okhudza maselo ambiri. Mfundo imeneyi timapitiriza kagayidwe mphamvu mu ischemic zimakhala m'mnyewa wamtima malo. "Panangin" - analogue "Asparkama" - chifukwa zili zofanana potaziyamu ndi magnesium asparginata akusonyeza chimodzimodzi zotsatira pharmacodynamic. Zimenezi zimalimbikitsa zayamba ofanana kuchuluka "Pananginum" mu mchitidwe mtima.

Makhalidwe pharmacokinetic wa

Sam "Asparkam" analogues mankhwala ndi mofulumira ndi pafupifupi kwathunthu kulowa makope zokhudza zonse. Excretion mankhwala kumachitika makamaka kudzera mwa impso. Pambuyo limodzi mlingo ndende pazipita mankhwala mu mtsempha wa magazi kukufika pasanathe maola 1-2. "Asparkam" m'magazi ukugwa monga ayoni a potaziyamu, magnesium ndi asparginatov maselo ayamba nawo njira zawo kagayidwe kachakudya.

zikuonetsa

Piritsi mawonekedwe "Asparkam" chiphunzitso anafuna (ndi bwino ntchito) zochizira matenda kugwirizana ndi insufficiency mtima. Choncho zikusonyeza kuti ikafike kungakhale postinfarction boma chikhalidwe pambuyo cardioversions kapena limodzi ndi arrhythmia ndi m'mnyewa wamtima conduction. "Asparkam" othandiza pa matenda a matenda a mtima ndi ntchito ya glycosides mtima, komanso zinthu cha mankhwala osokoneza bongo kapena poyizoni saluretikami (mankhwala diuretic kuti kuwonjezera kukula diuresis utithandize kulimbikitsa kuchotsa ayoni m'thupi).

The jekeseni mawonekedwe "Asparkama" wakhala bwinobwino ntchito mankhwala zovuta kulephera aakulu mtima, kuphatikizapo infarction pambuyo m'mnyewa wamtima, matenda a mungoli ndi conduction mu mankhwala kuphatikiza.

Contraindications mankhwala

Chifukwa chakuti "Asparkam" lili yambiri magnesium ndi ayoni potassium ndi contraindicated pa kulephera pachimake ndi aakulu aimpso, komanso kuchuluka kudziwa zigawo limodzi kapena angapo mankhwala.

Mu mantha cardiogenic (pamene systolic magazi akutsikira m'munsimu 90 mamilimita Hg. V.) Kodi osavomerezeka ntchito "Asparkam" analogs. Malangizo ntchito limasonyeza kuti mankhwala amadziwikanso contraindicated matenda Addison ndi zinchito adrenal insufficiency, mu milandu vysokostepennoy atrioventricular chipika wodwala ndi okhutira mkulu wa potaziyamu ndi magnesium ayoni mu madzi a m'magazi.

N'zimene ndi Administration

Pamene ntchito piritsi mawonekedwe "Asparkam" mankhwala mapiritsi limodzi kapena awiri pambuyo chakudya katatu patsiku. Nthawi mankhwala anatsimikiza ndi dokotala kupezeka zochokera Inde matenda a matenda ndi deta zasayansi ndi njira malangizo.

Mawonekedwe injectable akapatsidwa okha makonzedwe mtsempha. Nkhani za mbale wina ayenera zidzasungunuka mu 50 kapena 100 ml wosabala isotonic shuga njira, kutumikiridwa m'nsinga pang'onopang'ono. Mobwerezabwereza makonzedwe Mungathe kubwereza angotha maola 4-6 pambuyo yapita kopita "Asparkam" kukonzekera. Analogs wa mankhwala (mwachitsanzo, "Panangin") amapatsidwa zofanana. "Panangin" ngati "Asparkam", ali ndi chikoka kutchulidwa pa kagayidwe wa myocardiocytes. Choncho, analogue ichi "Asparkama" mu Russian chimagwiritsidwa ntchito mu zipatala cardiology.

zotsatira zoyipazi

Ngati kulandira piritsi mawonekedwe zavuta yatsoka matenda a thirakiti m'mimba, amene anaonetsa ululu ndi moto epigastric, nseru, kusanza. makonzedwe aakulu zingachititse zilonda za mucosa lapansi.

Popeza mankhwala ali ndi chikoka osakhala pa dongosolo mtima, pa mbali zikhoza arrhythmias, conduction zipolowe, chipika atrioventricular, kutsitsa magazi.

mantha dongosolo anati pakutchulidwa wa paresthesia, kumva kulasalasa, kukokana.

Chifukwa okhutira mkulu wa ayoni magnesium ndi malowedwe awo mu dongosolo chapakati mantha mwina kupuma maganizo ntchito. nthawi zambiri komanso amalembedwa kumayambiriro kumva kutentha "Asparkam" mankhwala. Analogs mankhwala ndi zizindikiro zofanana ndi mosiyanasiyana chowawa ndipo pafupipafupi asayembekezere. Poona zimenezi, khalani okonzeka kuwafunsa kulandiridwa isanafike wodwalayo mankhwala.

malangizo Special ntchito "Asparkam" mankhwala

Analogs ana ankagwiritsa ntchito odwala Dokotala, ngakhale pakadali pano osakwanira deta pa ntchito "Asparkama" ana. Ngakhale zili chomwechi, mankhwala lakhala likugwiritsidwa ntchito bwinobwino zochizira matenda a mtima mu Pediatrics.

Ngati yaitali mankhwala "Asparkama" analimbikitsa polojekiti mosamala electrolytes mu madzi a m'magazi, kuwunika magawo electrocardiographic. Komanso ndi kusamala kwambiri mankhwala ntchito odwala ndi milingo okwera potaziyamu mu madzi a m'magazi.

"Asparkam": Anzawo

Pakati pa msika panopa mankhwala angaperekedwe "Asparkam" mankhwala ndi kupereka "Panangin". Ndi dzuwa mkulu, yogwira analogi "Asparkama" chimagwiritsidwa ntchito mu Russia monga ali ndi dongosolo zofanana ndi ankalemekeza zizindikiro zofanana. Ndipo cardiology mchitidwe chitsanzo. Motero, "Panangin" - analogous kuti "Asparkama" ndi zikuchokera chomwecho.

Mwa mankhwala ena ndi kuchita chimodzimodzi tisaiwale, "Inosine" "Riboxinum" "Meksaritm" "Propanorm" "Ritmokard".