Kodi "Ranitidine" ndi chiyani? Kuchiza kwa zilonda zam'mimba ndi zilonda zam'mimba mothandizidwa ndi "Ranitidine"

Kodi "Ranitidine" ndi chiyani? Musanayankhe funsoli, nkofunikira kudziwa zomwe zakonzedwa ndizo, momwe zimapangidwira, momwe ziyenera kutengedwa komanso muyezo wotani?

Zambiri zadzidzidzi

Kodi "Ranitidine" ndi chiyani? Mankhwalawa ndi antiulcer mankhwala omwe amathandiza kwambiri kuchepetsa voliyamu yamadzi.

Kuyika kwa mankhwala ndi mawonekedwe ake omasula

Mankhwalawa "Ranitidine" amapezeka mu ma fomu awa:

• Mapiritsi omwe ali ndi 300 mg ndi 0.15 g wa mankhwala othandizira (ranitidine monga mawonekedwe a hydrochloride). Mankhwalawa amapitirira kugulitsidwa zidutswa 100, 30 kapena 20 mu katoni.
• Yankho la jekeseni. Mankhwalawa amagwiritsidwa ntchito pokhapokha ngati kugwiritsa ntchito mankhwala pamlomo pazifukwa zina sikutheka. Njira yothandizira mankhwala imagulitsidwa ndi ampoules a 2 ml.

Pharmacodynamics

N'chifukwa chiyani Ranitidine nthawi zambiri amauzidwa ndi madokotala? Mankhwala oterewa, kapena m'malo mwake amagwiritsidwa ntchito, m'malo mofulumira amachepetsa kuchuluka kwake kwa mimba yam'mimba, kumasulidwa kumene kumayambitsidwa ndi kupweteka kwakukulu kwa thupi. Kawirikawiri, vutoli ndilo chifukwa cha kuchuluka kwa zakudya zamtundu wa zakudya, komanso zimakhudzidwa ndi zochitika zina zotchedwa biogenic (histamine, acetylcholine, gastrin, pentagastrin ndi caffeine) ndi mahomoni.

Pambuyo pogwiritsa ntchito mankhwalawa "Ranitidine" mu wodwala, mucosa wa chimbudzi chachikulu chimalimbikitsidwa, ndipo kuchuluka kwa hydrochloric acid mu madzi ake kumachepa kwambiri. Izi ziyenera kuzindikiritsidwa kuti kugwiritsa ntchito mankhwalawa, kusintha kwa ntchentche sikusintha ndipo ntchito yowonjezera ya chiwindi siidakanidwa.

"Ranitidine" mankhwala amachititsa kuti kuchiritsidwa ndi kuchiritsidwa kwa zonse zowonongeka mu chapamimba mucosa, zomwe zimagwirizanitsidwa ndi kukhudzana ndi hydrochloric acid. Zotsatira za mankhwalawa ndi chifukwa cha kuwonjezeka kwa mapangidwe am'mimba. Malinga ndi malangizo, mankhwala "Ranitidine" mu mlingo wa 0.15 g amalepheretsa kusungunuka kwa madzi a chimbudzi chachikulu cha maola 8-13.

Kodi "Ranitidine" ndi chiyani?

Mankhwalawa amagwiritsidwa ntchito pazinthu zotsatirazi:

• Zilonda za duodenum ndi m'mimba (makamaka pa siteji ya kuchuluka);
• Kutupa kwa mimba, yomwe imabwera chifukwa choponya mmenemo zomwe zili m'mimba (ndi reflux-esophagitis);
• Kutupa kwa mimba chifukwa cha kuphwanya umphumphu wa mucosa (ndi matenda oopsa) ;
• Ndi zilonda zam'madzi zozizwitsa komanso zofulumira za duodenum ndi m'mimba, chifukwa cha kupanikizika, kumwa mankhwala ena kapena matenda ena a ziwalo;
• Zilonda za m'mimba zokhudzana ndi chotupa chofewa (ndi matenda a Zollinger-Ellison).

Ntchito yopewera

Mankhwalawa "Ranitidine" m'mimba samatengedwa kokha kuchipatala, komanso pofuna kupewa zotsatirazi:

• Kuwonjezereka kwa matenda a zilonda zam'mimba;
• Zilonda za m'mwamba mwa chigawo cha m'mimba;
• Kusakaniza kwa madzi a m'mimba mu tsamba lopumako panthawi yopatsira opaleshoni (pansi pa anesthesia).

Zotsutsana za ntchito

Mapiritsi ochokera mmimba "Ranitidine" ayenera kutengedwa pokhapokha atakambirana ndi dokotala. Pambuyo pake, mankhwalawa ali ndi zotsutsana:

• Mimba;
• Ali mwana (mpaka zaka 14);
• Hypersensitivity kwa mankhwala;
• Nthawi yogwirizana.

Komanso, mankhwalawa "Ranitidine" amalembedwa mosamala kwambiri pakakhala kuphwanya ntchito yodabwitsa ya impso.

Mlingo ndi njira zothandizira

Mankhwalawa amalembedwa mu mlingo woperekedwa malinga ndi matendawa:

• Ngati chilonda cha duodenum kapena m'mimba chikuchulukira, mankhwalawa amalembedwa kwa mapiritsi 1 kawiri pa tsiku kapena 0.3 g usiku. Ngati pakufunika mwamsanga, mlingo wa tsiku ndi tsiku wa wothandizira ukhoza kuwonjezeka kufika 400-450 mg.
• Pofuna kupewa zilonda za duodenum kapena m'mimba, mankhwalawa amalembedwa pa 0.15 g nthawi yomweyo asanagone (kamodzi pa tsiku).
• Mu matenda a Zollinger-Ellison, mankhwalawa pa mlingo woyamba amalembedwa kuchuluka kwa piritsi limodzi katatu patsiku. Ngati pangakhale zofunikira kwambiri, mankhwala omwe angatchulidwe amatha kuwonjezeka mpaka 0,7-0.9 g patsiku.
• Pamene zilonda zimachitika pambuyo pa opaleshoni, mankhwalawa "Ranitidine" akulimbikitsidwa kutenga 0.15 g kawiri tsiku lililonse. Monga lamulo, kuchiritsa kumachitika masabata 4 otsatira.
• Pofuna kupewa zowononga, mankhwalawa amapatsidwa mapiritsi 2 kawiri pa tsiku.
• Mapiritsi "Ranitidine" pofuna kutsekemera amalimbikitsidwa kuti atenge kuchuluka kwa chinthu choyamba kawiri pa tsiku.

Pofuna kupewa matenda opatsirana ndi kutuluka kwa magazi, mankhwalawa "Ranitidine" ayenera kugwiritsidwa ntchito intramuscularly kapena intravenously kwa 0.1 kapena 0.05 g maola asanu ndi awiri kapena asanu ndi atatu.

Zotsatira zoyipa

Mankhwalawa amachititsa zotsatira zotsatirazi:

• Kuthamanga kwa khungu;
• Chizungulire;
• Thrombocytopenia;
• Mutu;
• Kutopa.

Nthawi zambiri, "Ranitidine" amadwala tsitsi. Komanso, mankhwalawa akhoza kutsogoloza ndikukula kwa chisokonezo. Podya nthawi yayitali, wodwala amawonjezera prolactin, pali gynecomastia, leukopenia, impotence, amenorrhea ndi kuchepa libido. Nthawi zina, kugwiritsira ntchito mankhwala ngati amenewa kungayambitse chitukuko cha chiwindi.

Malangizo apadera

• Mankhwalawa ndi osamala kwambiri amauzidwa kwa odwala matenda oopsa kwambiri kapena odwala matenda oopsa.
• Musanayambe kulandira chithandizo ndi mankhwala awa, kukhalapo kwa matenda oopsa a m'mimba, mphukira kapena duodenum ayenera kuwonetsedwa.
• Ngati vutoli likufunika kwambiri, mankhwalawa amachotsedwa pang'onopang'ono kuchepa kwa mlingo.
• Kugwiritsa ntchito kogwiritsira ntchito kogwiritsira ntchito pokonzekera masiku 50 m'dzinja-kasupe nthawi yayitali kusiyana ndi kulandiridwa kwawo nthawi zonse.

Zizindikiro zimatanthauza

"Zantak", "Rantak", "Ranisan", "Acilok", "Ulran", "Ulkodin", "Ranigast" ndi "Ranitidine-Akos" ndizofanana ndi mankhwalawa. Kodi ndalama zonsezi zimachokera kuti? Iwo ali ndi chigawo chimodzi chogwira ntchito, ndipo chotero zizindikiro za mankhwala otero ndi ofanana.