Mankhwala "Buserelin Long" ndi analogue kupanga wa timadzi zachilengedwe GnRH. The ntchito chida ichi ndi mpikisano mwachindunji kumanga kwa maselo maselo pituitary ndi wotsatira chosakhalitsa kuwonjezeka kuchuluka kwa mankhwala kugonana plasma, amene pamapeto pake zimachititsa blockage lathunthu la otchedwa gonadotropic pituitary ntchito. Chifukwa cha mankhwala "Buserelin Long" amaperekedwa mwachindunji kupondereza timadzi kaphatikizidwe mu gonads, amene kumaonekera monga kuchepa madzi a testosterone (akalozera kuti muyike-castration) amuna ndi kuchepetsa magazi estradiol kuti muyike-azimayi amsinkhu umenewu amakumana makhalidwe odwala wamkazi. Mbali yoyamba tinganene castration pharmacological, wachiwiri - pa postmenopausal kapena ovariectomy.
Mankhwalawa amachoka mu kamphindi monga lyophilizate ndi mwapadera kuti akonze slurry. The zikuchokera kukonzekera izi zimabweretsa pakati zikuphatikizapo za 4 mg wa buserelin nthochi. zigawo wothandiza monga carmellose sodium, ndi copolymer wa glycolic ndi DL-lactic asidi, polysorbate 80 ndipo D-mannitol.
Pankhani ntchito mankhwala, yoikidwiratu wothandizila "Buserelin Long" zochizira khansa ya m'mawere ndi timadzi amadalira khansa prostate. Komanso, mankhwala angagwiritsidwe ntchito pa matenda a endometriosis. Zochizira fibroids uterine ndi osabereka (kudzera pulogalamu lidzawagwiritsenso) ayenera kuyamba kugwiritsa ntchito mankhwala "Buserelin-Long". Reviews madokotala umboni za ubwino wa ntchito zochizira njira endometrial hyperplastic.
Ngati ife kulankhula za contraindications yaikulu ntchito, ndiye ntchito mankhwala mosamalitsa contraindicated anthu ndi munthu tsankho buserelin nthochi, komanso ina zigawo zake mothandiza. Komanso, contraindications monga mimba ndi mkaka wa m'mawere.
Payokha, izo ziyenera kunenedwa za zotsatira zotheka mbali ya ntchito ndalama "Buserelin-Long", monga zingakhale Mwachitsanzo, chifukwa cha urticaria, angioneurotic edema ndi hyperemia. Komanso, pangakhale zinthu monga demineralization, kugona zipolowe, mutu ndi maganizo. Odwala wamkazi kubva m'mimba, kusintha libido, kuchuluka thukuta, menstrualnopodobnye magazi ndi dryness wa mucosa chikazi chifukwa ntchito mankhwala kupanga "Buserelin-Long". Zotsatira zake zoyipa mwa amuna makamaka kugwirizana ndi exacerbation la matenda vutoli, posungira mkodzo, gynecomastia, ndi "impso chotupa." Komanso akhoza kudzakhala kuchepa potency, kuchuluka thukuta, kufooka minofu ku malekezero ndi fupa ululu. A ochepa odwala kuona zochita monga matenda otsegula m'mimba , ndi embolism m'mapapo mwanga.