Mankhwala "Novirin": malangizo ntchito, analogs ndi ndemanga

Kupanga mankhwala mavairasi oyambitsa ndi ikupita patsogolo kwambiri. Asayansi ndi mankhwala, malo kafukufuku patsogolo akuyesetsa mwakhama kuti apeze zinthu zatsopano yogwira kulimbana ndi matenda sioneka, amene kuvulaza mpaka kalekale thanzi lathu ndi inu. Mmodzi wa mankhwala amakono ambiri mavairasi oyambitsa ndi "Novirin". Malangizo ntchito, mbali ntchito, ndemanga madokotala ndi odwala, komanso mavuto sanaphe mankhwala ife kuphimba m'nkhani ino.

Mu mawonekedwe zimene zikupezeka ndi zimene zikuchokera mankhwala?

Piritsi chiphunzitso "Novirin" ankanyamula mu matuza zidutswa 10 ndipo anaikidwa makatoni 2 kapena 4 mbale.

A mankhwala piritsi chikukhudza:

1. Waukulu yogwira pophika - pranobex inosine mu kuchuluka kwa 500 mg.
2. zigawo owonjezera: mbatata wowuma, ndi magnesium stearate.

Monga ntchito mankhwala?

mankhwala mankhwala amatsogolera mwachindunji tizilombo matenda. Kukonzekera "Novirin" chikuphatikizapo gulu zovuta mamolekyulu inosine: N, N-dimethylamino-2-propanol: N-atsetamidobenzoynoy asidi mu chiŵerengero cha 1: 3: 3, motero. zinthu izi kumumanga ndi ribosomes ali maselo kachilombo mavairasi. Chifukwa cha njira ya kaphatikizidwe ndi RNA, kugawanika kwa RNA ndi DNA ya zamoyo tizilombo pang'onopang'ono pansi. M'mawu ena, siyani mavairasi kuchulukitsa ndi kufa. Zovuta za yogwira zosakaniza mankhwala otchedwa inosine pranobex. Iye kukomoka kutsimikiziridwa kuti mavairasi oyambitsa ndi immunomodulating ntchito.

Mankhwala "Novirin" ayankhe madokotala ndi odwala ndi HIV. Akatswiri onani zosiyanasiyana zake:

• limatuluka kuti lithe interferon;
• kumawonjezera ntchito ya T-lymphocytes ndi phagocytic kanthu za macrophages;
• Amachititsa kuti amasulidwe lymphocytes chisanadze T;
• Iwo kumakulitsa kuchuluka kwa B ndipo T lymphocytes;
• kuchuluka dzuwa la T-lymphocytes kupanga lymphokines;
• dekhetsa chiŵerengero, amene T-athandizi ndi T-suppressors;
• 1 nadzawonjezapo pa mapangidwe interleukin-2;
• ntchito malamulo NK-maselo;
• kuchuluka mphamvu phagocytic wa macrophages;
• kukula kwa maselo amene mudameretsa oteteza.

Kulandira kutanthauza 'Novirin "ndi nsungu tizilombo Iyamba mapangidwe chitetezo, kuchepetsa zizindikiro matenda a matenda ndi amachepetsa pafupipafupi musabise. Maselo a m'thupi, ndi yogwira zovuta mankhwala kumathandiza kuchepetsa RNA kaphatikizidwe, kuchepetsa katundu pa thupi la wodwalayo ndipo amakhala asanazolowere ake.

Pambuyo "Novirin" (mapiritsi) wakhala ankadya ndi woleza mtima, mofulumira odzipereka ndipo akusonyeza digiri yapamwamba ya bioavailability. Anthu oposa theka amayamba kusonyeza zotsatira mavairasi oyambitsa, amene kumatenga maola 6. magawanidwe mankhwala Peak wapezeka pambuyo 60 min. pambuyo makonzedwe mankhwala. Inosine ndi zimapukusidwa ndi chiwembu cha nucleosides purine. Si anadzadza ndipo excreted ku chamoyo mu mawonekedwe zikutsatiridwa ndi monga kwathunthu opangidwa kuchokera kwa maola 48.

Kodi matenda kukuonetsedwa mankhwala?

"Novirin" (mapiritsi) akusonyeza kuti odwala matenda a chikhalidwe tizilombo, mosaganizira udindo m'thupi. Dokotala nawo mwina mankhwala a matenda otsatirawa:

• Fuluwenza ndi parainfluenza.
• ARI.
• matenda tizilombo.
• Matenda kugwirizana ndi rhinovirus ndi adenovirus.
• Chikuku.
• Kuderako mumps.
• Herpes zosiyanasiyana.
• Panencephalitis.
• Nthomba mphepo.
• Herpes zoster mtundu.
• Epstein-Barr HIV.
• Tsitamegalovirus.
• Atamwa chiwindi B.
• Anthu papillomavirus.
• matenda aakulu a kupuma ndi urogenital dongosolo muyambirenso anthu ndi chitetezo wofooka.

Monga mukuonera, kuwerenga mndandanda uli wamkulu mokwanira, zimene zimapangitsa mankhwala otchuka ndi osiyanasiyana m'malo lalikulu la matenda.

Kodi ndimagwiritsa ntchito mankhwala?

Pa funso la mmene bwino "Novirin" malangizo Buku zimapangitsa malangizo awa:

1. Mapiritsi kumwedwa pakamwa pambuyo chakudya ndi madzi kapena Kutha mu pang'ono.
2. Kusunga intervals chomwecho pakati kudya mankhwala.
3. Pakuti mogwira pazipita, mankhwala ayenera kuyamba ndi chida pamene mawonetseredwe woyamba zizindikiro.
4. Inde nthawi ndi mlingo wa mankhwala anaika dokotala, malinga ndi chikhalidwe cha wodwala, zaka, mtundu wa matenda, chikhalidwe ndi mmene chithandizo zikutanthauza portability.
5. The pazipita chovomerezeka mlingo "Novirina" odwala wamkulu - mapiritsi 8 maola 24, Chofanana 4 ga inosine pranobex.
6. mankhwala akhoza kumwedwa panokha kapena monga mbali ya chithandizo zovuta.

The njira ya mankhwala awa wothandizila mankhwala zambiri kwa masiku 5 mpaka 14. Koma nthawi zina, monga chofunika, dokotala akuonetsa kukonzanso Kusankhidwa pambuyo yopuma masiku 7-10. Chovomerezeka nthawi kulowa "Novirin" kukonzekera malangizo ntchito amatanthauza miyezi 6 mogwirizana ndi malangizo a phwando mkombero ndi mpumulo pakati.

Monga tanenera poyamba, mlingo ndi nthawi ya mankhwala zotchulidwa dokotala phwando ake ndi matenda makamaka ndi mtima. Ubwino wa mankhwala mankhwala ndi "Novirin" zovomerezeka chiphunzitso cha ana oposa 1 chaka. Odwala lipoti kusakanikirana kwambiri kwa dzuwa - harmlessness, khalidwe la mankhwala.

Mlingo ndi nthawi ya mu matenda osiyanasiyana

Nthawi ya SARS, fuluwenza ndi parainfluenza mankhwala zakonzedwa:

• Akuluakulu - mapiritsi 2 atatu kapena kanayi pa maola 24 Kutalika kwa masiku 5-7.
• Ana - mlingo wa 50 mg / kulemera makilogalamu thupi kwa maola 24, nagawira nambalayi ndi 3-4 Mlingo fractional. Kutalika kwa kutanthauza kulandira zimasiyanasiyana masiku 5 mpaka 7.

Nthawi zambiri zowonetseredwa ndi zizindikiro za kuchepa mu masiku 3-5 kuyambira mankhwala, koma ayenera kubweretsedwa pamaso pa mapeto a mpikisano. Ngati adotolo amati ndikofunikira, mungathe kubwereza mankhwala pambuyo yopuma sabata.

Mankhwalawa tizilombo matenda mankhwala "Novirin" malangizo Buku zimapangitsa malangizo awa:

• Akulu ayenera kumwa mapiritsi 2 katatu pa tsiku kwa masabata 2-4.
• Pa matenda omwewo "Novirin" anatumizidwa ana mu kuchuluka kwa 50 mg / kulemera makilogalamu thupi, ogaŵikana Mlingo 3 kapena 4. Chithandizo komanso kumatenga masabata 2 mpaka 4.

Pankhani ya mumps inosine pranobex kutumikiridwa mu kuchuluka 70 mg / kulemera makilogalamu thupi. mankhwalawa lagawidwa maola 3-4 pa tsiku. Chithandizo akupitiriza masiku 7-10.

Ngati wodwala wapezeka armature, omwe anaikidwa "Novirin" mu mlingo wa 100 mg / kulemera makilogalamu thupi. Kuchuluka kwa mankhwala lagawidwa mbali 3-4, phwando ikuchitika ndi intervals ofanana nthawi. Kutalika kwa mankhwala zingakhale za masiku 7 mpaka 15.

mankhwala "Novirin" ndi anasonyezanso kuti stomatitis aphthous. mankhwala ntchito malangizo otsatirawa:

• Ana inosine pranobex ayenera kugwiritsidwa ntchito mu kuchuluka 70 mg / kulemera makilogalamu thupi, mbali 3 kapena 4 ofanana. Patapita masiku 6-8 mlingo mankhwala yafupika 50 mg / kg thupi, amene analandira katatu kapena kanayi pa tsiku kawiri pa mlungu kwa masiku 49.
• Akulu ayenera kumwa mapiritsi 2 lokonzekera "Novirin" nthawi 4 kwa maola 24. Kutalika kwa chithandizo ayenera kukhala masiku 6-8. Itatha nthawi iyi, mlingo yafupika mapiritsi 2 katatu patsiku kawiri pa mlungu kwa masiku 42.

Ngati wodwala cytomegalovirus matenda kapena mononucleosis, ndiye izo tikulimbikitsidwa kuti mankhwala "Novirinom" mu kuchuluka kwa 50 mg / kg thupi. Zimenezi zimapereka mlingo ogaŵikana Mlingo 3 kapena 4 ofanana maola 24. Nthawi mankhwala mu tsetamegalovirusnom matenda kwa masiku 25 mpaka 30, ndi mononucleosis - masiku 8.

"Novirin" ndi anasonyezanso zochizira matenda herpetic ya kutanthauzira osiyana ndi matailosi. ntchito yake bwino motere:

• Akulu ayenera kumwa mapiritsi 2 mankhwala nthawi 3 kapena 4 pa tsiku kwa masiku 10-15. Ngati wodwala matenda nsungu maliseche, inosine pranobex ayenera zimawononga mapiritsi 2 3 zina pa maola 24 kuti masiku 5-6 pa exacerbation. ayenera kumwa mapiritsi 2 maola 24 itatha nthawi iyi. Wothandiza kuchiza matenda amatenga miyezi 6.
• Ana mlingo ndi kuchita masamu mu chiŵerengero cha 50 mg / kulemera makilogalamu thupi. ndalamazo ayenera kumwedwa patsiku, mbali 3 kapena 4 ofanana. mankhwala ndi kwa masiku 10 mpaka 15.

Pankhaniyi subacute matenda encephalitis ayenera kutenga mankhwala "Novirin" mu mlingo wa 50 100 mg / kg kulemera mtima. Kuchuluka chifukwa lagawidwa 6 wofanana mbali ndi kutenga tsiku fupipafupi kwa masiku 8-10. Itatha nthawi iyi, yopuma ndi kubwereza mpikisanowo. Malinga ndi kusalekerera m'mbuyomo matenda, adokotala akhoza mankhwala kuchokera 2 10 achire mankhwala nthawi inosine pranobex.

Ngati wodwala anaulula matenda kugwirizana ndi matenda papillomavirus anthu, ndiye anatumizidwa kumwa mapiritsi 2 amatanthauza "Novirin" katatu patsiku mu masiku 14-28. Pambuyo togas wopirira timakalandira CO2 laser mankhwala kapena cryotherapy, akupitiriza kumwa mapiritsi 2 a mankhwala katatu pa tsiku kwa masiku 5. Kawirikawiri amalangiza kugwira 3 maphunziro, pakati pa amene amapanga yopuma mwezi umodzi.

Mankhwalawa chiwindi B kudzera lokonzekera "Novirin" wamkulu ayenera zimawononga mankhwala mapiritsi 2 3 kapena nthawi 4 pa tsiku mlingo wa masiku 15 kapena 30. Itatha nthawi iyi, wodwalayo kuyenera kuti mapiritsi 2 pa maola 24. Zinthu zimenezi akhoza kupitiriza kwa miyezi 3 mpaka 7.

Mu kukhalapo kwa odwala ndi wotsikirapo asanazolowere matenda aakulu wa genitourinary ndi kupuma dongosolo ntchito "Novirin" kukonzekera woyeneradi ndemanga yothandiza. Madokotala mavuto oterewa, Mpofunika kutenga mankhwala motere:

• odwala wamkulu kumwa 3 kapena 4 pa magome tsiku lililonse kuchuluka kwa ndalama 2 masabata 2-12.
• Ana kumwa chiphunzitso mu kuchuluka kwa 50 mg / kulemera makilogalamu thupi ndi kugawa mlingo ndi Mlingo 3 kapena 4 anagawa patsiku. Tiyenera kupitiriza mankhwala kwa masabata 3. Mungathenso kupereka "Novirin" (mapiritsi) ana m'masiku a masiku 7-10 pakati pa amene anakonza tchuthi cha nthawi chimodzimodzi.

Izi mankhwala wasonyeza zotsatira zabwino malangizo a chitetezo chokwanira wofooka odwala achikulire ndi magulu aang'ono zaka. The malangizo abwino kulandira "Novirin" mankhwala - ndemanga. Ana mankhwala kwambiri amathandiza kuonjezera kukana matenda tizilombo. Madokotala dziwani kuti phwando inosine pranobex wosatha ku masabata 3 mpaka 9 amathandiza kukwaniritsa khola milingo immunomodulatory odwala.

Features mankhwala

Ngati odwala achikulire amafuna mankhwala wothandizila mavairasi oyambitsa, "Novirin" kukwana. Komanso malangizo a mlingo wa pophika yogwira sanapangidwe. Komabe, Dziwani kufunika ulamuliro mosamala asidi uric m'magazi index wodwalayo pa njira yonse ya mankhwala.

Ngati dotolo n'kukulemberani phwando yaitali obweretsa mankhwala, zizindikiro izi muyenera zasayansi polojekiti:

• zinchito ntchito ya chiwindi;
• uric asidi ndende mu madzi kwachilengedwenso;
• magazi zotumphukira;
• Kugwira ntchito kwa impso.

Kodi "Novirin" mavuto?

Madokotala dziwani kuti mankhwala "Novirin" (mapiritsi) amakambirana odwala zabwino, natisunthitsa zambiri zachilendo, ngakhale ntchito yaitali. Komabe, pali ena mavuto, zimene zimafunika kuti sindilephera.

Nthawi zambiri zotsatira osafunika mankhwala "Novirinom" ndi kufupika kusintha kuchuluka kwa asidi uric mu thupi madzi index mtima. Amenewa chafotokozedwa ndi maonekedwe a kagayidwe wa pranobex inosine. Kumapeto kwa mankhwala mlingo umabwerera kwa mkati ponseponse thupi mu masiku pang'ono.

Pa mayesero matenda, "Novirin" mankhwala anali anandipeza ndipo zotsatira zina zoyipa za mankhwalawa:

• Ambiri kutopa, kufooka, mutu, manjenje, chizungulire, tulo matenda.
• Nseru, kusanza, kuphwanya chopondapo, ululu pa peritoneum ndi kukwera kwa madzi a michere m'mimba.
• Zotupa pa khungu ndi kuyabwa, ming'oma, angioedema angathe.
• Kukula urea asafe mu magazi, polyuria, arthralgia.

Ngati inu mungazindikire zizindikiro zimenezi ayenera kuonana ndi dokotala. Chithandizo ndi mankhwala ayenera kusiyidwa mpaka malangizo aŵa dokotala.

contraindications

Tisanayambe "Novirin" ayenera mosamala mfundo kapangidwe kake. Ngati wodwalayo ndi tilinazo chodziwa kuti zikuluzikulu ndipo yachiwiri ya mankhwala, tiyenera nthawi yomweyo kuuza dokotala. Mu milandu, mankhwala m'malo ndi lofanana kapena analogue - malinga mobisa dokotala.

Pakati pa contraindications kuti "Novirina" ali ndi udindo zotsatirazi:

• aakulu aimpso insufficiency;
• gout;
• hyperuricemia;
• osakwana zaka 1 chaka;
• urolithiasis.

CHENJEZO ayenera mankhwala "Novirin" zotsatirazi gulu la odwala:

• Okalamba odwala.
• A mbiri umboni giperurekemiyu, aimpso kukanika, gout ndi urolithiasis.

Ngati pa zinthu izi mankhwala a pranobex inosine anali akadali inakonzedwa, ayenera limodzi ndi polojekiti kuvomerezedwa asidi uric mu mkodzo wa wodwalayo index.

Kodi n'zotheka "Novirin" mimba?

Kufufuza zotsatira za inosine pranobex pa thupi la amayi apakati sichinayambe imachitika Choncho, deta zogwirizana palibe. "Novirin" akazi anapatsidwa pa nthawi imeneyi. Ndi zofunika kutenga mankhwala pamene yoyamwitsa.

ngati mankhwala interacts ndi mankhwala ena?

Mankhwala "Novirin" - mankhwala Kwalamulidwa mosamala ndi zoletsa xanthine oxidase ( "Allopurinol"). Kuchuluka tcheru kusamala pamene co-chithandizo ndi mankhwala, omwe amaonjezera excretion asidi uric mu mkodzo. Mankhwalawa monga thiazide kapena kuzungulira okodzetsa.

Kodi pali ambiri osokoneza?

Mu yochizira matenda, komanso mavuto matenda a mankhwala "Novirin" Nthawi cha mankhwala osokoneza bongo anali anaona.

Theoretically, chotero chodabwitsa angayambe pamene mukumwa mankhwala pa mlingo wa wamkulu kuposa analimbikitsa. Pankhaniyi, wodwalayo achuluke Kuchuluka kwa asidi uric mu mthupi. Zikatero, wodwalayo tikulimbikitsidwa chapamimba lavage ndi chithandizo ndi kuledzera.

Ngati pali analogs?

Mu zochitika zina, pamene wodwala ali ndi contraindication kulandira "Novirin" analogues mankhwala akhoza zotchulidwa dokotala fanizoli. mankhwala amene amaonedwa wothandizila mankhwala ndi mavairasi oyambitsa ndi immunomodulatory mankhwala a analogues ichi mankhwala. Njirazi ndi monga:

• "Engystol";
• "Umckalor";
• "Marimer";
• "Immunal";
• "Immupret";
• "Askotsin";
• "Geviran";
• "Limfomiozot";
• "Tamiflu";
• "Acyclovir" ndi mankhwala ena.

Komabe, vuto limene wodwalayo bwino kutenga - "Novirin" analogues kapena ofanana matanthauzo ake - Only oyenerera mankhwala katswiri.

Pomaliza, tisaiwale kuti mudziwe za kukonzekera "Novirin" womwe m'nkhaniyi ndi chosavuta Baibulo malangizo. Cholinga cha mankhwala monga mankhwala, mlingo ndi nthawi kumene ya anapereka dokotala yekha.