Antivirals

Mavairasi oyambitsa mankhwala - mankhwala zinthu pa mavairasi ndi kuwononga nyumba zawo kapena matenda yofunika ntchito.

Panopa anayamba okwanira mankhwala. Onse wachinsinsi ndi makhalidwe a zochita pharmacological ndi zizindikiro zenizeni zachipatala. Kuonetsetsa gulu zotsatirazi wa wothandizila mavairasi oyambitsa: kufala sipekitiramu antiherpethetical, protivotsitomegalovirusnye, fuluwenza, odana retroviral. Oimira odziwika kwambiri a mtundu woyamba wa mankhwala ndi "ribavirin" ndi "Lamivudine". Mankhwalawa ndi njira zovuta kanthu, zokhudzana ndi kuchepetsa zidulo mkati mwa kumanga kwa michere ya HIV. Monga dzina munda wa ntchito mankhwala ndi waukulu kwambiri ndipo ochuluka DNA - ndi mavairasi RNA timene chifukwa matendawa PC a malungo Lasa, chiwindi C, ndi AIDS.

mankhwala Antiherpethetical awa akuimira ndalama anayi, omwe ndi awo morphological dongosolo nucleoside analogi acyclovir, penciclovir, famciclovir, valacyclovir. The ziwiri zapitazi mitundu mlingo ali wofooka. Anthu, iwo anatembenukira kwa acyclovir ndi penciclovir. Izi zimapangitsa pafupi morphological ndi histological katundu wawo.

Limagwirira cha zochita za acyclovir ali mogwirizana ndi michere ndi tizilombo, inatuluka kaye mkombero chitukuko. Chifukwa ndi chiwonongeko cha tizilomboto lapansi. mogwirizana Izi amaperekedwa ndi kapangidwe ka acyclovir, chomwe ndi analogi dezoksiguanedina (purine nucleoside). yovuta kwambiri kwa mankhwala ndi nsungu simplex HIV. Pali mitundu tizilombo zomwe ndi kugonjetsedwa ndi mankhwala. Amenewa singalifotokoze ntchito mankhwala immunosuppressive. Limagwirira kukaniza ndi kusintha kwa kachitidwe HIV enzyme, kusintha kulunjika mankhwala. Mu chochitika cha zoterezi ndi mankhwala a magulu ena pharmacological ( "Foscarnet"). Ana antivirals monga "Valacyclovir." Mkulu bioavailability, lomwe ndi maperesenti oposa makumi asanu zimayambitsa zotsatira zofanana. Izi zikutanthauza kuti pamafunika mlingo laling'ono kwambiri la mankhwala (poyerekeza ndi "Acyclovir") kukwaniritsa zotsatira.

Limagwirira cha zochita za penciclovir pafupifupi palibe wosiyana zokonzekera za gululo. Komanso akuphwanya kaphatikizidwe DNKmikroorganizma. Komabe, kumasiyana kuti kwakukulukulu amakhudza Varicella-Zoster HIV (VZV).

Ndi protivomegalovirusnym mankhwala monga "Ganciclovir", "Valganciclovir", "Foscarnet", "Cidofovir", "Fomiversen". Ali ndi limagwirira m'malo zovuta kanthu, imene imakhudza mpikisano chopinga wa DNA polymerase wa bakiteriya a. The chifukwa cha zimachitika izi ndi contravention wa elongation wa unyolo DNA yomwe imatsogolera ku imfa yake. mavairasi oyambitsa mankhwala ambiri kuti kuthetsa zizindikiro za matenda cytomegalovirus - zikutanthauza gulu pharmacological. Komabe, pambuyo yaitali ntchito kukana mankhwala khateyo, amene penapake amachepetsa osiyanasiyana ntchito.

mankhwala mavairasi oyambitsa kungatithandize mwachindunji pa kamene kamawononga chitetezo m'thupi. Choncho ena asatayike, amene ali kanthu zofanana, pamodzi ma ARV gulu. Iwo onse ndi limagwirira zovuta kanthu amagwirizana ndi blockage kachitidwe enzyme wa chamoyo, kugawanika ake kuphwanya.