Mankhwala 'Zocor, malangizo ntchito, deta ya yakuthandizani

"Zocor" - mankhwala zokhudza mankhwala kuchipatala ndi pharmacological gulu hypolipidemic. The yogwira wothandizila chiphunzitso "Zocor" - simvastin, piritsi limodzi anyamula 10,20, ndi 40 mg, komanso wothandiza: ascorbic ndi citric asidi, butylhydroxyanisole, talc, mankhwala enaake a stearate ndi ena.

'Zocor' ndi zothandiza kwambiri, n'zothandiza kazembe kuchepetsa mafuta m'thupi. Zimenezi n'zofunika kwambiri makamaka mu hyperlipidemia losakanizika, chifukwa ndi matenda a wokhutira chodziwa imatengedwa chinthu choopsya. Pa nthawi ya masabata 2 n'zotheka kukwaniritsa noticeable mphamvu zabwino, zotsatira achire kusungidwa pa mlingo pazipita kwa 4 - 6 milungu. mafuta amagwanso kolowera koyamba pamene mwasiya mankhwala ndi 'Zocor, malangizo Buku lili kafukufuku pa mankhwala zambiri.

Kuwunika odwala mu kuchuluka pafupifupi 4.5 zikwi. Munthu anapangidwa kwa zaka 5.4. Konse phunziro anati mafuta m'thupi (mg / DL.), 212 - 309. phwando "Zocor" 30% yafupika chiopsezo imfa, chiwerengero cha infarction m'mnyewa wamtima ndi 37% (milandu anatsimikizira mu zoikamo matenda), 42% - imfa CHD. Mu 37 mtima mwa 100 panalibe akufunikira opaleshoni kuti normalization wa otaya inatsekeratu magazi.

Mu UK, zaka 5.5 kafukufuku odwala (anthu 20536) amene asunga kapena ananeneratu CHD. Mu gawo lachitatu la kuphunzira za chiopsezo cha sitiroko ndi matenda a mtima anachepetsedwa yochepa. Ndi kuti, koyamba mafuta msinkhu, ikufanana ndi kuchizira matenda, kugonana ndi zaka odwala sanali bwanji dzuwa la kumwa mankhwala "Zocor". Malangizo ntchito mwatsatanetsatane pharmacokinetics ake, asanalowe m'magazi ndi odzipereka kwa m'mimba thirakiti. Zakhala experimentally wasonyeza simvastina kudzikundikira mkulu chiwindi ndi ziwalo zina za ndende anapeza zedi laling'ono kwambiri, thunthu yogwira lachokera ku ya ndulu ya.

Ischemic matenda a mtima ndi umboni waukulu mankhwala "Zocor", malangizo ntchito amatanthauza kugwiritsa ntchito zina mwa zolinga zake:

- Ndi njira muyeso ndi vuto la mtima;

- liwiro ndondomeko atherosclerosis inatsekeratu;

- olimba a sitiroko, sitiroko kuchepetsa chiopsezo.

Pamene anakwezedwa kuchuluka kwa mafuta m'thupi mankhwala "Zocor" kumathandiza kuchepetsa ake ndi kupanda zakudya achire, komanso njira zina sanali pharmacological monga pamene hypercholesterolemia n'kukhala chinthu choopsya, n'koyenera kuti kapoloyu lekartsvennogo njira.

Mu pachimake kulephera gawo chiwindi amatanthauza contraindication kwa akuluakulu a mankhwala "Zocor". Malangizo ntchito komanso osavomerezeka ntchito mankhwala pa mimba kapena yoyamwitsa komanso kudziwika hypersensitivity kwa mankhwala.

"Zocor" amayambitsa zotsatira zina mbali ya dongosolo m'mimba. Ngakhale kutenga mankhwala "Zocor", mfundo mawu kuti kudzimbidwa zotheka, kupweteka m'mimba, pali zambiri pa milandu chiwindi, kapamba, matenda a chikasu ndiyo.

Zotsatira zoyipa anaona ndi kulemekeza dongosolo chapakati mantha, izi omangana minofu, chizungulire, neuropathy zotumphukira.

Kawirikawiri, koma thupi lawo siligwirizana zimachitika monga angioedema, vasculitis, volchanochnopodobnogo syndrome, nyamakazi, kuchuluka ESR, malungo, dyspnea, eosinophilia.

Nthawi cha mankhwala osokoneza bongo anapezeka zoipa mbali mawonetseredwe ankaona anatengera mlingo pazipita 450 mg.

Store mankhwala "Zocor" akulimbikitsidwa madigiri T Max 30, ngakhale zosakhalitsa kukhudzana T pafupifupi 50 madigiri ayenera kuzipewa.