Nchifukwa chiyani "Ibuprofen" (mapiritsi)? "Ibuprofen" - gel, mafuta, kuyimitsa: malangizo ogwiritsira ntchito, umboni. "Ibuprofen" (madzi a ana): malangizo othandizira

Nchiyani chomwe Ibuprofen chimaperekedwa kwa odwala? Tidzakuuzani za izi m'nkhaniyi. Kuchokera pamenepo mudzaphunzira za mawonekedwe omwe mankhwalawa anapangidwira, momwe angatengedwe, ndi momwemo.

Kuwongolera, kuika, kufotokoza, mitundu ya mankhwala

Kodi Ibuprofen amapanga mtundu wotani? Malangizo ogwiritsidwa ntchito, ndemanga za akatswiri amanena kuti mankhwalawa amapangidwa m'njira zosiyanasiyana.

• Mapulogalamu a Biconvex ndi mapiritsi ozungulira amagulitsidwa m'makhadi a makapu 20, 10 kapena 100. Iwo ali ndi ubweya wonyezimira ndi woyera. Chinthu chogwiritsira ntchito mankhwalawa ndi ibuprofen.
• Mapiritsi okhala ndi tebulo "Ibuprofen". Kuchokera pa mapiritsi awa, tidzanena pang'ono. Zimakhala ndi zochepa zomwe zimagwira ntchito, motero zimapereka chinthu chokhalitsa.
• Makapisozi. Fomu iyi ili ndi 300 mg ya mankhwala yogwira ntchito. Zimathera pang'onopang'ono.
• Kuwukitsidwa kwa Ibuprofen. Mbewu ya ana imabwera kugulitsidwa mu botolo ndi supuni yoyezera. Kuyimitsidwa ndi mtundu wofanana wa chikasu. Ikhoza kukhala ndi lalanje ndi katsamba kake.
• Suppositories Ibuprofen. Malangizo, ndemanga amanena kuti makandulo oterewa amagwiritsidwa ntchito movomerezeka. Iwo amagulitsidwa mu phukusi la zidutswa 10.
• The granules. Fomu iyi imagwiritsidwa ntchito pokonzekera njira yothandizira mankhwala ovomerezeka. Zomalizidwazo zili ndi zokometsera zokometsera, komanso zonunkhira bwino.
• 5% "mafuta a Ibuprofen". Kugwiritsira ntchito chida ichi kukuthandizani kuchotsa ululu m'misungo ndi m'magulu. Gelisi imagwiritsidwa ntchito pokhapokha.
• Yankho la jekeseni. Zimapangidwa ku Germany ndipo zimagulitsidwa pakadhiboard packs ya 4 capsules. Lowani mankhwala mozunguliridwa.

Mbali za mankhwala

Nchifukwa chiyani Ibuprofen amagwiritsidwa ntchito muzamankhwala? Malinga ndi malangizo, mankhwalawa ndi mankhwala osagwiritsa ntchito steroidal odana ndi kutupa. Amatha kukhala ndi anti-inflammatory, antipyretic ndi analgesic zotsatira. Akatswiri amanena kuti mankhwalawa amaletsa COX2 ndi COX.

Mfundo ya ibuprofen ndiyo kuchepetsa kaphatikizidwe ka prostaglandin, ndiko kuti, oyimira pakati pa kutupa, kupweteka ndi hyperthermia.

Pharmacokinetics ya mankhwala

Kodi ndi mankhwala ati a pharmacokinetic omwe mapiritsi a ibuprofen ali nawo? Kugwiritsiridwa ntchito kwa mawonekedwe a m'kamwa mwa mankhwala kumapangidwanso mofulumira komanso mofulumira kuchokera mu chigawo cha m'mimba.

Ibuprofen yapamwamba kwambiri mu pulasitiki imatengedwa patatha mphindi 120-240 pambuyo pake. Kulumikizana ndi mapuloteni a plasma ndi oposa 90%, ndipo kuthetsa hafu ya moyo ndi maola awiri.

Mankhwalawa "Ibuprofen" (kuyimitsidwa ndi mapiritsi) amalowa pang'onopang'ono kumalo. Zomwe zimagwira ntchito zimasungidwa mu minofu ya synovial. Izi zimapereka izi ndi kuika kwakukulu kwa zopangira.

Pambuyo poyamwitsa, pafupifupi 60 peresenti ya mtundu wosavomerezeka wa R wa mankhwalawo amasandulika kukhala mawonekedwe a S.

Mankhwalawa ndi ophatikizidwa. Zimasokonezeka kupyolera mu impso (zosasintha), komanso pamodzi ndi bile.

Zisonyezo za kugwiritsidwa ntchito kwa mtundu uliwonse wa mankhwala

Nchifukwa chiyani ibuprofen iyenera kuuzidwa kwa odwala? Malinga ndi malangizo, mankhwalawa ali ndi zizindikiro zotsatirazi:

• Matenda a msana ndi ziwalo zotupa (kuphatikizapo ankylosing spondylitis, nyamakazi ya nyamakazi ndi yovuta, osteoarthritis);
• Matenda a Febrile, omwe amapezeka motsutsana ndi matenda a matenda opatsirana;
• Zowawa zochepa zosiyana siyana (kuphatikizapo mutu, neuralgia, migraine, kupweteka kwapambuyo, kupweteka kwa dzino, myalgia, algodismenorrhea zoyambirira, zopweteka kwambiri).

Ndizinthu zina ziti zomwe Ibuprofen zingagwiritsidwe ntchito? Kodi mapiritsiwa amapereka chiyani kwa odwala? Madokotala amati mankhwalawa amagwiritsidwa ntchito mwakhama pofuna mankhwala opatsirana. Ndi zabwino komanso mofulumira kumachepetsa kutupa ndi kupweteka (pokhapokha pa nthawi yogwiritsira ntchito), koma kukula kwa matendawo sikukhudza.

Zotsutsana za ntchito

Pakuti "Ibuprofen" ikugwiritsidwa ntchito ndi odwala, ife tafotokozedwa pamwambapa. Pankhani yotsutsana, akuphatikizapo zifukwa zotsatirazi:

• Matenda owopsa ndi zilonda zam'mimba m'magazi, makamaka pa siteji yowonjezera (mwachitsanzo, zilonda za m'mimba 12, ntchentche, matenda a Crohn, matenda a zilonda zam'mimba);
• Kuchulukitsa mphamvu ya munthu kwa zosakaniza zomwe zimapanga mankhwala;
• Kuchulukitsa mphamvu kwa wodwala kuti asidi acetylsalicylic, komanso ma NSAID ena, kuphatikizapo anamnestic data pa rhinitis, kutsekedwa kwachisoni, ming'oma mutatha kutenga NSAIDs kapena acetylsalicylic acid;
• Matenda a matumbo a chikhalidwe cha kutupa;
• Kusakwanira kapena kwathunthu kusagwirizana kwa acetylsalicylic acid (kuwonetseredwa ngati rhinosinusitis, urticaria, polyps mu nasal mucosa, kupwetekedwa kwa mphumu);
• Nyengo pambuyo pa mitsempha yamakono ikuphatikizana;
• Hemorrhagic diathesis, hemophilia ndi mavuto ena mu magazi coagulability (mwachitsanzo, hypocoagulation);
• Kulephera kwachinyengo kunayambitsa, matenda osiyanasiyana a chiwindi;
• Kuchetsa magazi, kutsekemera kwa m'mimba;
• Kulephera kwachinyengo kunasonyeza, kunatsimikizira hyperkalemia;
• Matenda a impso opitirira.

Kodi ndi zotsutsana ziti zomwe zimapezeka kwa mankhwala a Ibuprofen? Siketi kwa ana sali oyamikira kuti apereke ana kwa miyezi itatu, ndi mitundu ina ya mankhwala - mpaka zaka zisanu ndi chimodzi. Komanso, mankhwalawa sayenera kugwiritsidwa ntchito pamene ali ndi mimba.

Kulandira mwaluso

Ndizifukwa ziti zomwe ndiyenera kugwiritsa ntchito mankhwalawa "Ibuprofen" mosamala kwambiri? Kugwiritsa ntchito (ndemanga za chida ichi zidzawonetsedwa mtsogolo) za mankhwalawa kwa okalamba, komanso anthu omwe ali ndi mtima wosagwira ntchito, matenda oopsa a mtima ndi matenda a mtima wamagetsi ayenera kuyang'aniridwa ndi dokotala.

Komanso, mwachindunji mankhwalawa amalembedwa ku matenda a cerebrovascular, dyslipidemia, shuga, matenda opatsirana (phokoso), kusuta, enteritis, kumwa mowa, chiwindi cha chiwindi, chifuwa chachikulu, matenda a nephrotic, hyperbilirubinemia, colitis, matenda a magazi osadziwika kuchokera pachifuwa Kudyetsa.

Njira zogwiritsa ntchito mankhwala

Njira zogwiritsira ntchito kukonzekerazi zimadalira mtundu wake wa kumasulidwa.

• Manyuchi.

Kodi Ibuprofen amawonetseredwa kuti ndi ana angati? Malangizo ogwiritsira ntchito amanena kuti, pokhudzana ndi mapiritsi, siketi imachita mofulumira kwambiri. Musanagwiritse ntchito fomuyi, botolo liyenera kugwedezeka bwino. Mlingo wa mankhwalawa uyenera kudziwidwa ndi adokotala okha, malingana ndi momwe wodwalayo alili.

• Makandulo.

Mafomu a "Ibuprofen" amapangidwa makamaka kwa ana. Amagwiritsidwa ntchito movomerezeka ndikuyamba kuchita maminiti 30. Ndi febrile kapena painful syndrome, mlingo umodzi wa mankhwalawa ndi 5-10 mg pa 1 kg ya kulemera kwa mwana. Ikani makandulo makamaka pafupipafupi maola 6-8.

• Gel, mafuta.

Ndingagwiritse ntchito bwanji mafuta a ibuprofen? Gel, chidutswa cha masentimita 1.5, chimagwiritsidwa ntchito ku zilonda ndi kuyenda kosavuta. Ayenera kupewa mwachangu kutenga mankhwalawa mu mabala ndi mabala otseguka. Apo ayi, mankhwala ayenera kutsuka nthawi yomweyo ndi madzi otentha.

• Mapiritsi.

Kodi mapiritsi a "Ibuprofen" ndi owopsa kwa ana? Malangizo ogwiritsira ntchito amanena kuti mtundu uwu wa mankhwala ndi wosafunika kupereka ana mpaka zaka 6.

Tengani mankhwala awa ayenera kukhala pakati pa chakudya. Kawirikawiri amauzidwa kuchuluka kwa 5-10 mg pa 1 makilogalamu a kulemera kwake katatu patsiku. Pankhaniyi, mlingo wa tsiku ndi tsiku usakhale woposa 20 mg pa kg.

Ndi matenda a nyamakazi, komanso matenda ena ammadzi, mankhwalawa amalembedwa mu 40 mg / kg (koma osati).

Milandu yowonjezereka

Pogwiritsa ntchito mankhwala osokoneza bongo, wodwalayo akhoza kukhala ndi zizindikiro zotsatirazi: kunyoza, kutseka, kupweteka kwa m'mimba, kugona, kusanza, kupweteka, kupweteka kwa thupi, kupweteka kwa magazi, kupwetekedwa kwa mutu, kupweteka kwa magazi, kuthamanga kwa magazi Matenda a m'mimba, kumangirira kupuma ndi tachycardia.

Kuchiza - kutsekemera mwamsanga (mkati mwa mphindi 60 pambuyo pa kutsekemera kwina), kulandiridwa kwa mpweya, zakumwa zamchere ndi diuresis yokakamizidwa.

Zotsatira Zotsatira

Kodi kukonzekera "Ibuprofen" kumapangitsa kuti zisonkhezero zisokonezeke? Gel osagwiritsidwa ntchito kunja sichimayambitsa zotsatira zoipa. Ponena za mawonekedwe a pamlomo a mankhwalawa, akhoza kupanga zotsatirazi:

• Kupweteka kwa m'mimba, kuchepa kwa njala, kupweteka pakamwa, kusanza, zilonda zam'kati, kupweteka kwa mtima, aphthous stomatitis, kutsekula m'mimba, kuuma kapena kukwiya kwa mucosa wamlomo, flatulence, pancreatitis, kudzimbidwa;
• Hepatitis;
• Bronchospasm, dyspnea
• Kumva kukhumudwa, phokoso kapena kulira m'makutu, kumva;
• Kuwopsya ndi maso owuma, scotoma, zilonda za poizoni za mitsempha ya optic, kuchepa kosamveka kapena kuwonongeka kwa masomphenya, edema wa maso ndi conjunctiva;
• Kusagona, kupweteka mutu, kukhumudwa, chizungulire, chisokonezo, nkhawa, kupsinjika maganizo, kukwiya ndi mantha, kugona, kugwedezeka maganizo, aseptic meningitis;
• Tachycardia, kulephera mtima, kuwonjezeka kwa magazi;
• Kulephera kwenikweni kwa mphuno, polyuria, matenda osokoneza bongo, nephrotic syndrome, cystitis;
• Kuthamanga kwa khungu, Quincke's edema, pruritus, exudative erythema multiforme anaphylactoid, malungo, anaphylactic mantha, dyspnea, bronchospasm, matenda a Stevens-Johnson, eosinophilia, epidermal necrolysis poizoni, opweteka rhinitis;
• Kuwonjezeka thukuta;
• Anemia, thrombocytopenic ndi thrombocytopenia purpura, leukopenia, agranulocytosis;
• Kuchepetsa kwa m'mimba mucosa, kutuluka magazi.

Tiyeneranso kukumbukira kuti kumwa mankhwalawa kungapangitse kusintha kwa zotsatirazi:

• Sera ya creatumine (yowonjezera);
• Kusuta nthawi (kumawonjezera);
• Kutaya kwa creatinine (kumachepetsa);
• Sera ya shuga yosungunuka (kuchepetsedwa);
• Hemoglobin kapena hematocrit (ikhoza kuchepa);
• Ntchito ya transaminase ya chiwindi (kuwonjezeka).

Ngati zoterezo zikuchitika, muyenera kusiya nthawi yomweyo kumwa mankhwala ndikumufunsa dokotala.

Malangizo apadera

Kuchiza ndi mankhwala "Ibuprofen" kuyenera kuchitidwa pa mlingo wocheperako, womwe udzasonyeze kuti ndizofunika kwambiri kuchiritsa. Njira ya mankhwala ikhale yoperewera.

Ngati mankhwala akuchitidwa kwa nthawi yaitali, ndiye kuti amafunika kuyang'anira impso ndi chiwindi, komanso chithunzi cha magazi.

Ngati zizindikiro za matenda a gastropathy zikuoneka, kuyang'anira mosamala mkhalidwe wa wodwalayo n'kofunika. Izi ziyenera kuphatikizapo esophagogroduodenoscopy, komanso madyerero a mwazi wamatsenga ndi mayeso ambiri a magazi (kuti apeze haemoglobin).

Kuyanjana kwa Mankhwala

Ndizovuta kwambiri kuphatikiza mankhwala a Ibuprofen ndi acetylsalicylic acid ndi zina za NSAID. Izi ndi chifukwa chakuti zingachepetse zotsatira zotsutsana ndi zotupa ndi antiplatelet za mankhwalawa.

Pomwe mumalandira mankhwala omwe akugwiritsidwa ntchito panthawi imodzimodziyo ndi thrombolytic ndi anticoagulant kukonzekera chiopsezo cha chitukuko cha kutuluka magazi.

"Cefaferazone", "Cefamandol", valproic acid, "Cefotetan" ndi "Plikamycin" amachititsa kuti chithandizo cha hypoprothrombinemia chikhale chokwanira.

Mankhwala omwe amaletsa kusungunuka kwapadera, amachepetsanso chisamaliro ndipo amachulukitsa ndende ya Ibuprofen.

Mankhwalawa amachititsa kuti mankhwala osokoneza bongo apwetekedwe, amachititsa zotsatira za mankhwala osadziwika bwino a antiticoagulants, fibrinolytics ndi antigregregants.

Ndemanga za odwala za mankhwala

Mankhwalawa "Ibuprofen" ndi otchuka kwambiri pakati pa odwala. Amakhala ngati wothandizira kwambiri wotsutsa-kutupa, omwe ali ndi mitundu yambiri ya kumasulidwa.

Malingaliro a odwalawo, mankhwalawa amayamba kuchita mofulumira kwambiri. Amachotsa ululu waukulu kwambiri m'magulu ndi minofu, komanso amathetsa mutu ndi kutupa kwa mitundu yosiyanasiyana.

Njira yokhayo ya mankhwalawa ndi kupezeka kwa zotsatira zambiri ndi zosiyana. Malinga ndi ndemanga za odwala, mankhwalawa "Ibuprofen" amachititsa kuti ululu wa m'mimba, ntchentche, chizungulire ndi kusanza, komanso zimayambitsa zilonda zam'mimba m'matumbo. Choncho, gwiritsani ntchito mankhwalawa akulimbikitsidwa mu mlingo wochepa, komanso kwa nthawi yochepa. Mwa njira iyi mungathe kuthetsa ululu wa syndromes ndipo nthawi yomweyo musamamvepo mbali iliyonse.