Njira zobisika. 'Mafuta' a Clotrimazole '

Clotrimazole ndi mafuta onunkhira, zofanana ndi zosavuta kwenikweni.

Zinthu zothandizira mankhwalawa ndi: polyethylene oxide 400, propylene glycol, proxanol-268, kukonzekera OC-20, cetyl stearyl mowa. Thupi logwira ntchito ndi clotrimazole.

Mafuta amatanthauza antchito omwe amachititsa kuti asamangidwe . Njira yogwiritsira ntchito mankhwalawa imadalira kuchepa kwa kaphatikizidwe ka ergosterol, komwe kuli kofunikira pomanga maselo a fungalomu. Kuletsedwa kwa ndondomekoyi kumayambitsa kuswa kwa chiwerengero cha selo.

Mafuta opangidwa ndi clotrimazole amachititsa kuti chiwerengero cha liposomal phospholipid chikhale chopitirira, kutulutsa phokoso la cytoplasm, kuchepetsa chiwerengero cha ribosomes. Chifukwa cha mphamvu ya yogwira ntchito, ntchito ya peroxidase imaletsedwa. Izi zimathandizanso kuti pulogalamu ya feteleza ya hydrogen peroxide ipangidwe m'seri, yomwe imachita nawo chiwonongeko.

Mafuta a clotrimazole ali ndi zotsatira zambiri. Mankhwalawa ndi othandiza polimbana ndi dermatophytes, yisiti bowa. Kuphatikiza apo, imakhala ndi antibacterial action kwa streptococci ndi staphylococci.

Kukonzekera kumakhala ndi mphamvu yowonjezera. Ndizogwiritsa ntchito kunja kwa epidermis, mankhwala osokoneza bongo ndi apamwamba kusiyana ndi minofu yachitsulo ndi udzu. Mafuta a clotrimazole m'magazi amagazi sagwiritsidwa ntchito. Chifukwa cha ichi, kumwa mankhwala mopitirira muyeso sikungatheke.

Mafuta clotrimazole. Ntchito

Kukonzekera kwa mankhwala kumawonetseredwa ku matenda omwe amabwera chifukwa cha dermatomycetes, nkhungu nkhungu, blastomycetes ya mycoses, komanso maambukidwe achilendo ( dermatomycosis wa misomali, mapazi ndi ena).

Mankhwalawa amagwiritsidwa ntchito kawiri kapena katatu patsiku pa malo okhudzidwa ndi kuzitikita. Kutalika kwa njira zothandizira kumadalira kuchitika ndi kuopsa kwa matendawa, kumidzi komwe kumatulutsa matenda, ndi kupambana kwa mankhwala. Kawirikawiri, nthawi ya maphunziroyo ndi masabata anai kapena kuposerapo. Pochiza mycosis ya phazi pofuna kupewa kuchepetsa matendawa, mankhwalawa amapitirira kwa milungu itatu mutachotsa zizindikiro za matendawa. Asanagwiritse ntchito mankhwalawa pamapazi, ayenera kutsukidwa ndi madzi asapu, makamaka malo osungirako, ndi zouma. Malo omwe mankhwalawa angagwiritsidwe ntchito ayenera kukhala oyera komanso ouma.

Pa ntchito yoyamba nthawi zambiri zochitika zapadera zimawululidwa, zimafotokozedwa mu reddening, kutentha, kuyabwa. Monga lamulo, mawonetseredwe awa amatha ndi kugwiritsa ntchito mankhwalawa.

Kusiyanitsa kwa kugwiritsa ntchito mankhwala ndi hypersensitivity kwa mankhwala yogwira ntchito (clotrimazole) kapena zigawo zina za mankhwala.

Pali kuchepa kwa zotsatira za mankhwala ndi ntchito yake imodzimodzi ndi othandizira ena. Zotsatira za clotrimazole zikhoza kuchepetsedwa ndi kugwiritsidwa ntchito kwa dexamethasone mu mlingo waukulu.

Podziwa kwambiri, mankhwalawa ayenera kugwiritsidwa ntchito ndi amayi pa nthawi ya kuyamwitsa komanso pa nthawi yomwe akuyembekezera. Tiyenera kukumbukira kuti mankhwalawa amakhudza thanzi la mwana ndi mayi. Funso la kugwiritsira ntchito mankhwalawa m'magulu amenewa limasankhidwa mwachindunji patatha kuyankhulana kwachipatala.

Musagwiritse ntchito mankhwalawa kumaso pafupi ndi diso.

Ngati kugwiritsira ntchito mankhwala sikuthandiza kuthetsa zizindikiro za matendawa mkati mwa masabata anayi, m'pofunika kutsimikizira kuti matendawa ndi otani.

Pakupita patsogolo kwa kuwonjezeka kwachisokonezo kapena kumvetsetsa m'deralo, ndi koyenera kusiya mankhwala ndi kusankha chithandizo china.