"Propranolol": analogues, malangizo ntchito, kufotokoza ndi ndemanga

"Propranolol" - mankhwala cha gulu la blockers kusankha. Mankhwala mavuto antianginal, antiarrhythmic ndi hypotensive. The medicament kutumikiridwa cholinga cha mankhwala a matenda ischemic mtima, thyrotoxicosis, matenda oopsa. Mankhwala ndi othandiza mu neuro dystonia, migraine. Ndi ntchito kukhazikitsa chithandizo cha matenda a mtima, angina pectoris. Mankhwala kupindula thupi infarction m'mnyewa wamtima. Alikuchitira arrhythmia ndi cardiomyopathy hypertrophic. Pamene wodwalayo si abwino "Propranolol" Akhristu amaona kuti ndi prescribers katswiri kuti wodwalayo ndi mulingo woyenera.

Fomu kumasulidwa

Mugule mitundu iwiri ya mankhwala - mankhwala "Propranolol" mankhwala "Propranolol Nycomed". Izi ndi mankhwala yemweyo amene amapangidwa ndi opanga osiyana mu magome.

The zigawo zikuluzikulu za mankhwala

lokonzekera anapangidwa pamaziko a yogwira mankhwala propranolol. Mlingowu chigawo chachikulu angakhale osiyana - 10, 40, 80 ndi 160 mg wa mu zikuchokera aliyense piritsi.

zosakaniza wothandiza ntchito popanga miyala ndi osiyana ndi zimadalira opanga. Kudziwa kwenikweni chimene chiri mwa mankhwala pamaso ntchito m'pofunika kuwerenga bukhuli.

Zotsatira achire mankhwala

Alili luso ndigwire zolandilira beta-adrenergic amatanthauza "Propranolol" malangizo Buku. Analogues pa thupi ofanana kanthu. Mapiritsi bwanji pa mtima beta maselo makoma 1 ndi 2. Zotsatira ochepetsera pa maselo amenewa kumabweretsa zosangalatsa makoma mtima, ndipo potero adzathetsa ambiri mwa mavuto - kuthamanga magazi, kuwonjezeka mtima chopezera mpweya, perekani osauka zakudya ndi mpweya zimakhala ndi ziwalo.

kanthu Antiarrhythmic mankhwala amalimbikitsa maonekedwe a anasinthira thupi, monga nkusani mfundo automaticity normalization, kuchepa conduction atrioventricular mfundo, Kupha kuchuluka excitability wa maselo mzati weni weni wa myocardium. Chifukwa cha "Propranolol" kubwezeretsedwa ntchito yachibadwa mtima, palibe anachita zikuchitika kunja, zomwe zingathe kusokoneza mungoli ake.

"Propranolol" analogues kulimbikitsa chitukuko cha zotsatira odana anginal omwe akusonyeza boma bwino minofu mtima, kuchepetsa kuchuluka kwa mpweya chofunika chifukwa ntchito zake. Izi zikutanthauza kuti mtima amafuna zochepa mpweya kuchepetsedwa ndi pafupipafupi contractions izi yafupika kwambiri.

kanthu Hypotensive zachokera kuwonjezeka mu lumen Mitsempha ndi zosangalatsa makoma awo. Ntchito mlingo umodzi miyala kumabweretsa kuchepetsa wa magazi, zotsatira chifukwa ali anapitiriza kwa maola osachepera 20 usiku. Khola hypotensive zotsatira unkachitika pambuyo masabata awiri a ntchito zonse za mankhwala. Mankhwala si abwino kwa mpumulo wa zinthu limodzi ndi kuwonjezeka lakuthwa mu kuthamanga, izo akusonyeza kuti mankhwala kwa nthaŵi yaitali oopsa.

ntchito nthawi yaitali mankhwala kumabweretsa chitukuko cha zotsatira cardioprotective. Onetsani kuchepa Mwina zisadzachitikenso wa infarction m'mnyewa wamtima pambuyo mankhwala amenewa amatanthauza "Propranolol" ndemanga, malangizo. Kwambiri yafupika chiopsezo imfa yadzidzidzi zikuchitika. Amadziwika kuti mankhwala kuli ndi ubwino pa intraocular kuthamanga okwera.

Pharmacokinetics

Ikalowa mkatimo thupi Mbali yaikulu imatsala mankhwala (90%), pamene zosonyezera bioavailability ndi negligible. Kulankhulana ndi mapuloteni lolingana 93%. Mankhwala kwa thupi kuchotsedwa mkodzo, amene amagwa metabolites. mitundu zonse ali peresenti pasanathe wina wa mankhwala.

umboni

"Propranolol" analogues malangizo limakupatsani perekani mankhwalawa zinthu zina ndi matenda. Iwo ankachitira oopsa zipata ndi wolumikizira, m'mnyewa wamtima dystrophy, hyperthyroidism. Mankhwala kumathandiza kuziziritsa chikhalidwe pa lumen mwapang'ono kwa msempha, kugwedeza zofunika, amantha, angagwiritsidwe ntchito ngati chida ntchito mu prophylaxis la migraine. Mapiritsi oyenera mankhwala mu mtima msilikali m'mnyewa wamtima infarction, arrythmia. mankhwala chikuyendetsedwera odwala mitral vavu prolapse. Mwa zizindikiro ndi monga supraventricular tachycardia ndi nkusani. Potumiza njira anachita pa matenda achire, angina pectoris, akathisia, akuwuka chifukwa ntchito neuroleptics. Mankhwala zotchulidwa odwala pheochromocytoma kwa mankhwala osakaniza. Mankhwala ntchito kufooka kwa ntchito ntchito pambuyo kusintha kuti athetse mawonetseredwe zake zoipa.

contraindications

Pali ena contraindications kuti "Propranolol" mankhwala. Analogs akhoza anasankha pa nthawi imene mankhwala si abwino. Contraindications monga:

• tsankho limatanthauza zigawo;
• cardiogenic mantha;
• bradycardia, imene chiwerengero cha heartbeats pa mphindi 55 SP.
• kagayidwe kachakudya acidosis;
• kulephera aakulu mtima kapena mitundu pachimake;
• vasomotor rhinitis;
• sinoatrial chipika, atrioventricular (2, digiri 3);
• Prinzmetal angina ;
• otsika magazi;
• Ntchito insulin;
• syndrome limodzi ndi nkusani;
• kukhalapo nthawi imene pano yaitali kudya;
• mavuto ndi makope zotumphukira (decompensation sitepe);
• poyamba anasamutsa malangizo matenda amene anakhudzidwa Airways, mphumu, bronchospasm kupezeka.

Palinso zinthu komwe kusamala chofunika. Nthawi yotsatira, mukhoza kusankha m'malo mankhwala "Propranolol" analogues, ofananira:

• myasthenia gravis;
• shuga (decompensated, subcompensation);
• mtima minofu insufficiency (mphumu), chiwindi, impso;
• chonsechi matenda a m'matumbo;
• maganizo;
• atrioventricular chipika (digiri yoyamba);
• psoriasis;
• kuchuluka ntchito ya chithokomiro England;
• mitundu aakulu chifuwa;
• otsika shuga;
• ndiko kumayambitsa;
• ukalamba;
• Woyembekezera, breastfeeds.

mankhwala

Odwala matenda oopsa ayenera kumwedwa mankhwala mlingo kawiri pa tsiku la mg ndi 40 pa mlingo umodzi. Kuchulukitsa kwake n'zotheka mwa masiku 14-28. Ngati ndi kotheka, mapiritsi akhoza kumwa tsiku ndi tsiku mlingo wa mg ndi 80 160. Pafupipafupi njira kulandira ali yemweyo.

Pamene tachyarrhythmia odwala wamkulu kumwa katatu kapena anayi tsiku 10 30 mg wa pa phwando "propranolol" amatanthauza. Analogs angagwiritsidwe ntchito, ngati mankhwala si woyenera. odwala wamng'ono ndi vuto lomwelo la mankhwala kutumikiridwa mu ndalama kuchokera mg wa 0.2 kuti 0.4 pa kulemera kilogalamu thupi. Pafupipafupi ntchito zikutanthauza - monga katatu kapena kanayi pa tsiku.

Monga njira muyeso odwala amene amadziŵika angina anaika anayi kumwa mankhwala tsiku ndi tsiku. A mlingo umodzi wa 20 mg. Kuchulukitsa kwake n'zotheka masiku asanu ndi awiri. 40 mg wa mankhwala akutengedwa pa mlingo chomwecho, 80 mg - pang'ono zochepa zambiri (kawiri).

Pambuyo prophylaxis m'mnyewa wamtima infarction chofunika. Ndinathamangira akhoza medicament "Propranolol". Kukula abwino umodzi mlingo ndi 40 mg, ndi madyerero mankhwala patsiku ayenera kuperekedwa atatu. Kuwonjezera mlingo mpaka munthu pazipita 80 mg.

Migraine zodzitetezera ayenera kukwaniritsa ntchito mg wa 40 wa mankhwala kawiri pa tsiku. Amafuna kuwonjezeka mlingo 80 mg, kumwa mankhwala tsiku ndi tsiku mwina awiri kapena atatu, ndi ana - atatu kapena anayi. Mawerengedwe a mlingo odwala ndi yaing'ono anachita m'nkhani za thupi lawo, pa kilogalamu wa - kuchokera 1.5 kuti 2 mg.

Thyrotoxicosis - matenda imene mankhwala umaperekedwa 10 mg koma osapitirira 40 kulandira katatu kapena kanayi pa tsiku.

Ngati mukufuna mankhwala pheochromocytoma, mankhwala ali pamodzi ndi blockers Alpha.

zotsatira zoyipazi

Kodi kulabadira zimene amasankha mavuto mankhwala "Propranolol" malangizo Buku. Analogs ndemanga - si mfundo zofunika kwenikweni, kulimbikitsa kusankha mankhwala mankhwala. Kuti chiopsezo zosiyanasiyana chokhwima ya thupi kochepa, m'pofunika mwawerenga mosamala malangizo, m'pofunika timudziwe bwino.

Mankhwala ngati ntchito molakwika akhoza kuwononga dongosolo mtima chifukwa cha zipolowe mu dongosolo chapakati mantha, dongosolo endocrine. N'zotheka mawonetseredwe zoipa pa mbali pa mundawo m'mimba, akhoza kusokoneza nembanemba mucous ndi khungu. Mwa mavuto kutchulidwa malangizo - mavuto kupuma. Pangakhale zotsatira zina zoyipa.

mtengo Analogs

Pamaso kugula "Propranolol" analogues mankhwala, mtengo kawirikawiri anaphunzira odwala. Kugula mankhwala kungakhale kwa 16-75 rubles. Price anatsimikiza ndi nambala ya mapiritsi pa paketi. Sinthanitsani mankhwala akhoza kukhala "Propranobene" medicaments "obzidan" kapena "Inderal". Mukhozanso kupanga mankhwala "Inderalom LA", "Inderalom".

Ndi Buku mankhwala "Propranolol" malangizo ntchito, mtengo, analogs kupereka zofunika kuti amathandiza kusankha bwino posankha mankhwala ndi mankhwala.

Reviews

Reviews makamaka positive. Iwo anati kuti mankhwala zambiri zothandiza. Komanso, ambiri ali ndi mankhwala mtengo otsika. "Propranolol" amalowerera kusunga magazi pa mlingo wabwinobwino, mwamsanga muchisiye palpitations mtima. Mankhwala kuchepetsa matenda a mtima, kumatha kutengeka kwa umunthu. ndemanga zoipa zambiri anthu kusiya chifukwa cha zotsatira zina zoyipa omwe angagwe pa mankhwala. Nthawi zina kwambiri kufooka, tulo, malubwelubwe.