"Spironolactone": analogues, malangizo, ntchito, malongosoledwe mankhwala

"Spironolactone" - ndi potaziyamu ndi magniysberegayuschy diuretic. The mankhwala ndi wamphamvu diuretic, amene kumathandiza leaching thupi la salt kwambiri. Komanso Sachita acidity wa mkodzo. M'pofunika kulabadira, kuyesera m'malo mankhwalawa "spironolactone". Analogs mankhwala si nthawi zonse likhale katundu amenewa.

Kapangidwe ndi Kaonekedwe

Izi mankhwala ndi alembedwe piritsi. Yogwira chigawo ndi spironolactone. Mu piritsi limodzi lili 25 kapena 100 mg wa thunthu. Komanso imakhala ndi zigawo wothandiza: wowuma mbatata, monohydrate, lactose, povidone, calcium stearate. Miyala yochititsa ankanyamula mu katoni zidutswa 20.

zotsatira pharmacological

Mankhwala "spironolactone" ndi aldosterone antagonist. Ndi timadzi adrenocortical. Aldosterone kaphatikizidwe ndi maselo mapuloteni wapotalikira maselo nephron amachepetsa excretion wa soda ndi madzi ndi kuonjezera leaching potaziyamu. "Spironolactone" kupikisana ndi timadzi ichi ndi zochita zosiyana. lokonzekera amalimbikitsa excretion wa madzi ndi sodium wochuluka m'thupi, kusunga ndi ayoni potaziyamu. Electrolyte bwino ndi maganizo.

Panopa mwangwiro anaphunzira pharmacodynamics mankhwala. Pa chikuonetseratu kuti mundawo m'mimba ndi odzipereka mofulumira ndi kumanga kwa mapulotini plasma. Bioavailability miyala pafupifupi 99%. Wina anaponya zakudya Iyamba mayamwidwe wa yogwira mankhwala yogwira mankhwala.

Zotsatira achire, malinga ndi malangizo chimachitika mu masiku 5. Pamafunika kudzikundikira ake pang'onopang'ono thupi ku ndende zina mankhwala kuti yambitsa. Apo ayi, mu ntchito zachipatala iwo akutchedwa zotsatira chokhala. Yogwira mankhwala likulowerera mofulumira mu mkaka wa m'mawere, ndipo anachokera ku thupi pamodzi ndi ndowe ndi mkodzo. Amene matenda madokotala mankhwala "spironolactone"?

zikuonetsa

The malangizo "spironolactone" inanena kuti mankhwala cholinga mankhwala matenda otsatirawa ndi pathologies:

• Edematous matenda amenewa amapezeka pa maziko a matenda a mtima.
• Hyperaldosteronism.
• N'kofunika oopsa.
• hyperaldosteronism Secondary chifukwa cha kuwuma kwa chiwindi.

Mankhwala a matenda ayenera kuyamba atakambirana ndi dokotala.

contraindications

Mu zina, ali osavomerezeka kutenga mankhwala "spironolactone"? Zikuonetsa ntchito anapereka pamwamba si chifukwa chololera chithandizo. Izi mankhwala mavuto ambiri mbali ndi contraindications.

The malangizo kwa Administration Mankhwala ananena kuti ntchito yake zolinga achire ali osavomerezeka chifukwa anthu ndi Addison ndi matenda, hypercalcemia, matenda a shuga. Ndi kusamala kwambiri ayenera kugwiritsidwa ntchito mankhwala kuti akazi ndi kulephera kupita kumwezi, chifuwa kukulitsa.

Malangizo ntchito

medicament Izi ndi oyenera makonzedwe m'kamwa. mlingo anatsimikiza ndi dokotala anthu paokhapaokha, zochokera azikhala kuyan'anila za bwino madzi-electrolyte ndi milingo m'thupi la wodwalayo.

Pamene edema anachititsa syndrome neurotic mankhwala ali anayamba ndi 100-200 mg wa mankhwala patsiku. Mlingo ayenera kugawidwa Mlingo awiri kapena atatu. Kutalika kwa mankhwala pafupi masabata atatu. Pankhani ya hyperaldosteronism ndi magazi otsika potaziyamu medicament "spironolactone-Darnitsya" amagwira ntchito mg wa 300 patsiku.

Pa ndi matenda hydropic, amagwirizana ndi chikhalidwe aakulu a insufficiency mtima, mankhwala masiku 5. mapiritsi ndi kutumikiridwa mu mlingo wa 100-200 mg. Komanso, odwala zambiri zotchulidwa thiazide ndi kuzungulira okodzetsa. Pamene mphamvu zabwino kuchira mlingo pang'ono ndi pang'ono kuchepa kwa 25 mg pa tsiku.

zotsatira zoyipazi

Kodi mavuto ali "spironolactone"? Analogs za mankhwala ali portability osauka. "Spironolactone", mosiyana, yodziwika ndi mayamwidwe mofulumira ndi zabwino achire zotsatira. Nthawi zina matenda ndi mavuto, imene mawonekedwe kukodzedwa pansipa.

1. Kagayidwe: kusintha asidi-m'munsi bwino, hyperuricemia.
2. CNS: kuchuluka tulo, litsipa, ulesi.
3. mitsempha ya magazi: megaloblastoz, thrombocytopenia.
4. GI: ululu m'mimba, zilonda za m'mimba, matumbo omangana, kutsekula m'mimba.
5. dongosolo Endocrine: erectile kukanika, chifuwa carcinoma, brutalization voti.
6. thupi lawo siligwirizana: kuyabwa zidzolo, ming'oma.

Ngati mwakumana ndi zizindikiro ayenera kuonana ndi dokotala monga tafotokozazi. Monga ulamuliro, katswiri wasankha m'malo "spironolactone". Analogs za mankhwala komanso ndi mavuto, koma anapempha mmene wamng'ono.

Kusamala

Pa mankhwala "spironolactone":

• Ndi bwino kupewa kudya zakudya kuti ali wolemera potaziyamu.
• Kutiletsa ndi mowa.
• Iwo sayenera kugwiritsa ntchito munthawi yomweyo medicaments mu zikuchokera amene potaziyamu alipo.

Ngati mankhwala zina anatumizidwa NSAIDs, m'pofunika kuti aziona kugwira ntchito kwa impso ndi zizindikiro za electrolytes m'magazi.

Mu koyamba gawo wa mankhwala Ndi bwino kupewa galimoto magalimoto ndi ntchito ndi njira yaikulu imene amafuna ndalama mkulu wa zochita psychomotor ndi chidwi. Kutalika kwa malamulo otere amayikidwa payekha, zochokera tolerability, "Spironolactone".

Mtengo wa mankhwala ndi zinthu yosungirako

Mtengo wa mankhwala zimasiyanasiyana mlingo wake. Kwa ma CD imodzi miyala kulipira kwa rubles 30 mpaka 50. The mtengo okwana chimadaliranso malire, amene anapereka unyolo ambiri mankhwala.

Malinga ndi malangizo, lokonzekera kusungidwa pa kutentha osati madigiri apamwamba kuposa 20, asaawone manja malo ana. Alumali moyo zaka 3.

analogues mankhwala

Kodi mankhwala akhoza m'malo ndi "spironolactone"? Analogs wa medicament nthawi zambiri ndi zikuchokera ofanana ndi ndende ya chigawo chachikulu. Zikuphatikizapo mankhwala zotsatirazi: "Veroshpilakton", "aldactone", "Veroshpiron". Yotsirizira nthawi zambiri ntchito mu malo Nkhani za m'nkhaniyi mankhwala.

Mwa mankhwala odziwika generic zotsatirazi: "Dekriz", "Inspra", "Espirit", "Epletor". Limagwirira cha zochita mofanana ndi "spironolactone". Zizindikiro ndi bioavailability wa chomwecho. okodzetsa Awa kwambiri zothandiza kuti normalization wa magazi, achire wa madzi owonjezera m'thupi. Komabe, generic pafupifupi sateteza ndi leaching wa potaziyamu ndi magnesium, Komabe, madokotala ambiri amakonda kugwiritsa ntchito mankhwala pachiyambi.

kuti adzimvera

Tsopano inu mukudziwa kodi pathologies ndi matenda adzaika "spironolactone". Mtengo wa mankhwala ndipo limapezeka ambiri - i ziwiri zazikulu ndi zomwe odwala ambiri amakonda medicament izi. Ambiri ndemanga zabwino komanso kutsimikizira kwambiri yabwino "spironolactone".