Calprotectin ali muchitsime - ndi chiyani? Zifukwa za kuwonjezeka

Calprotectin ali muchitsime - ndi chiyani? Ndi mapuloteni omwe amamasulidwa ku leukocyte (macrophages ndi neutrophils) patsiku lawo kapena imfa. Amakhala ngati chizindikiro cha kutupa komwe kumachitika m'matumbo. Ndondomeko yowonjezera ya phunziro ili ndi yofanana ndi chiwerengero cha leukocyte m'matumbo.

Calprotectin ali muchitsime - ndi chiyani?

Thupi limeneli limatha kutulutsidwa kuchokera ku leukocyte (neutrophils) yomwe yaikidwa kale kapena yakufa kale. Ndipotu, ndi mapuloteni kapena mapuloteni omwe amapezeka ndi calcium. Calprotectin mu nyansi zozizira - ndi chiyani, ndipo zimakhala zotani m'matumbo?

Mu matenda opweteka a m'magazi, chiwerengero cha leukocyte mmenemo chimakula. Ma leucytes, omwe amatchedwa neutrophils, akulimbana ndi matenda, omwe amachititsa imfa. Akafa, kutulutsidwa kwa mapuloteni - calprotektin, ndipo izi zimapangitsa kuti chiwerengero chawo chiziwonjezeka kwambiri.

Kutsimikiza kwa kuchuluka kwa calprotectin mu nyansi zochokera m'zinyenyeswazi ndi njira yosavuta komanso yosavuta yodziŵira matenda opatsirana a m'magazi (IBD). Matendawa amavomereza dokotala wodwalayo kuti amusiyanitse IBD ndi matenda omwe amachititsa kuti thupi likhale lopweteka kwambiri, lomwe njira yotupa yamatumbo (GI tract) mucosa siyimene .

Atasankhidwa?

Phunziroli lapatsidwa ngati wodwala ali ndi madandaulo otsatirawa:

• Zithunzi zosawerengeka ndi kusakaniza kwa ntchentche.
• Choponderetsa madzi ndi kusakaniza magazi.
• Ululu m'mimba ndipo nthawi yomweyo ukuwonjezeka kutentha kwa thupi.
• Kuwonjezeka thukuta.
• Kuchepetsa kupweteka kwa thupi.
• Kufooka kwathunthu ndi kutopa mofulumira ndi kuchitapo kanthu pang'ono.
• Ngati pali kuphwanya kwa m'mimba motility.
• Ndi mseru ndi kusanza.
• Ndi kudzimbidwa.
• Pomwe pali wodwalayo wodwalayo, ngati abscesses kapena fistula.
• Kwa ana kumapeto kwa chitukuko.

Calprotectin mu nyansi zozizira: kawirikawiri

Makhalidwe amenewa amatha kuchokera ku 0 mpaka 10 mg / ml. Ngati m'madzimadzi amtundu wa calprotectin uli mkati mwake, izi zikutanthauza kuti wodwalayo alibe IBD. Mphungu yamkati ya m'matumbo siinatenthe. Ndipo ngati wodwalayo akupitirizabe kudandaula za vuto la matumbo ndi zotayirira, izi zikhoza kutanthauza kuti ali ndi vuto lopweteka m'mimba. Kufotokozera za matendawa kungafunike kufufuza kwina.

Kodi kukula kwa calprotectin mlingo kumatanthauza chiyani?

Ngati calprotectin mu nyansi zam'madzi akukwera, zifukwazi zingagwirizane osati ndi IBD, komanso ndi matenda a tizilombo kapena mabakiteriya a m'mimba, mwachitsanzo, salmonellosis, campylobacteriosis. Zomwezo zimayambitsidwa chifukwa cha kukhalapo kwa rotavirus, adenovirus kapena norovirus. Kuphatikiza apo, calprotectin m'madzimadzi amatha kukwezedwa chifukwa cha mkaka wa ng'ombe kapena matenda a celiac (kusagwirizana kwa gluten komwe kumakhala ndi miyambo yambewu), komanso pamaso a mafinya, diverticulum wa m'matumbo kapena mucoviscedosis (matenda obadwa nawo okhudzana ndi matenda a endocrine omwe amachokera kunja).

Kodi ndizifukwa zotani zomwe kafukufuku wapangidwira?

Taganizirani pamene phunziro lapangidwa, zomwe zimatithandiza kudziwa calprotectin mu nyansi zakutchire. Ndi chiyani icho, ife tachipeza kale.

Phunziro lotero lapatsidwa kwa odwala:

1. Monga kafukufuku wodzitetezera ngati akuyesedwa kuchipatala.
2. Ndi kukayikira kulikonse kwa IBD.
3. Kutuluka magazi m'mimba.
4. Pamene wodwalayo akudandaula za kupweteka m'mimba komanso chithunzi chogwirizana nacho.
5. Kuchepetsa matenda odwala matenda opatsirana.

Ndiyenera kuchita chiyani?

Ngati zinaoneka kuti calprotectin mu nyansi zam'madzi zimakwera, dokotala ayenera kudziwa zifukwa zomwe zimayendera. Mulimonsemo, sikofunikira kudzipangira yekha mankhwala. Ikhoza kukhala matenda aakulu kwambiri. Kuti dokotala azindikire molondola, nthawi zina maphunziro angapangidwe:

• Chipulogalamu.
• Zimene Gergersen anachita, kapena kusanthula mwazi wamatsenga . Kufufuza koteroko kumafuna maphunziro apadera. Pakadutsa masiku atatu wodwala sayenera kudya nyama ndi nsomba, komanso zakudya zomwe zili ndi chitsulo (chiwindi, mazira, black currant, chokoleti).
• Puloteni wothandizira kwambiri ndi njira yowopsya yomwe ingalolere kufotokozera zotsatirazo.
• Chifuwa chachikulu.
• REA (khansa embryonic antigen).
• ANA (antibodies to antigen nuclear).
• Kafukufuku wambiri wa magazi ndi chiwerengero chovomerezeka cha mankhwala a leukocyte.

Chithandizo

Choncho, adokotala amadziŵa bwino lomwe, pomwe pali zizindikiro za kutupa kwa m'mimba mucosa, motero calprotectin amatha kuwonjezeka. Chithandizo chidzadalira chifukwa chimene chimachititsa kutupa uku.

Ngati cholakwa cha chirichonse ndi matenda opatsirana, mwachitsanzo, salmonellosis, ndiye mankhwala amafunika omwe angawononge causative wodwala matenda (salmonella). Zidzakhalanso zofunikira kuti muzitenga zitsulo, mwachitsanzo, "Liferan", "White coal", "Enterodez", "Smektu", ndi zina zotero. Kuwonjezera apo, mankhwala amafunikira kutibwezeretsa mchere wa madzi: "Oralit", "Regidron", ndi zina. Maonekedwe a salmonellosis nthawi zambiri ma antibayotiki saperekedwa, chifukwa Wothandizirawa amatha kuzipewa.

Mu chiwopsezo cha tizilombo toyambitsa matenda (adenovirus kapena rotavirus, etc.), mankhwala osokoneza bongo amafunika. Zikhoza kukhala "Arbidol", "Gordoks", "Virazol", ndi zina zotero. Yesetsani kusamalitsa thupi ndi kutulutsa mankhwala osokoneza bongo "Cycloferon", "Anaferon", "Interferon".

Kawirikawiri, mankhwala oletsa maantibayotiki amaperekedwa kuti athetse matenda opatsirana m'mimba. Mwachitsanzo, perekani "Ftalazol", ndipo ana akugwiritsa ntchito mankhwala osokoneza bongo otetezeka kwambiri ndi "Action".

Zotsatira zabwino zimaperekedwa ndi kukonzekera kwa enzymatic "Enzistal", "Festal".

Koma kusankhidwa kwa mankhwala ayenera kokha dokotala, malinga ndi momwe munthuyo amadziwira ndi matenda ake.