"Formetin": malangizo ntchito kwenikweni

Panopa tinapeza anthu ambiri shuga ndi mavuto a mtundu kunenepa. mankhwala ambiri akupezeka zochizira matenda amenewa. Mmodzi wa iwo ndi mankhwala "Formetin". mbali zake zazikulu zidzafotokozedwa m'nkhani ino.

gulu mankhwala

"Formetin" malangizo ntchito chomwe chili m'nkhani ino, ndi biguanide hypoglycemic mankhwala gulu.

Kufotokozera za kapangidwe ndi kumasulidwa mawonekedwe

Mu umodzi wa piritsi ake:

Mukhozanso mankhwala "Formetin" mu matuza 100, 60 kapena miyala 30.
Mtundu White miyala ndi mlingo mawonekedwe zimadalira zinthu m'munsi. Pa 500 mg ploskotsilindricheskoy ali ndi mawonekedwe zozungulira ndi chizindikiro ndi chamfered. Komanso mlingo wa 1000 mg kapena 850 mg wa lili "Formetin". Miyala mu nkhani iyi, otukukira kunja ndi chowulungika. Ali chiopsezo mmodzi ndiye amaganiza.

pharmacodynamics

Metformin ( "Formetin") kubweza gluconeogenesis osefukira chiwindi, motero pali kuchepa m'masitolo glycogen izo. chida zimenezi kumathandiza kuti n'kovuta mayamwidwe ku shuga matumbo, kumapangitsanso excretion a dongosolo shuga. Zimenezi zimene zimakhala kuti insulin popanda okhudza yopanga endocrine gawo ake a kapamba B-maselo, anyalanyaza hypoglycemic anachita, chifukwa si adamulowetsa yopanga anati mankhwala.

Mankhwala "Formetin" ndemanga yomwe kulankhula za nchito zake, kuchepetsa kuchuluka kwa magazi mu "oipa" mafuta ndi triglycerides. The zili lipoproteins mkulu osalimba kumawonjezera izi 20-30%. Ndi kupanda zakudya mankhwala "Formetin" malangizo ntchito amene akambidwa mu nkhaniyi kumathandiza kuchepetsa ndi / kapena ziziyenda kulemera kwa wodwalayo. Izi zimachitika chifukwa makutidwe ndi okosijeni a shuga ndi mpweya-free ndi kuchepetsa njala. Ndiponso blunted minofu plasminogen kutsegula ndondomeko mumatsatira woletsa ake, mmene hemostatic zotsatira akuwonekera.

Pharmacokinetics

Kuloŵerera metformin kumayambira thirakiti m'mimba. Kuchuluka pazipita thunthu mu magazi za 2.5 maola pambuyo ntchito pa mlingo wa mayamwidwe wagawo mlingo - 50-60%. Suction khalidwe la mankhwala mu thupi amakhudza kugwirizana pakati pa mankhwala yogwira ndi mapuloteni mu madzi a. Mapiritsi "Formetina" palibe kugwirizana kwa mapulotini plasma. Iwo amalankhula za nchito zake. Popeza ang'onoang'ono chinthu kumanga, mankhwala ndi bwino chosakanikirana. Mafunsidwe ndi impso, chiwindi, ndi minofu minofu, mu zopangitsa ndi malovu. Mu thupi, metformin amakhalabe sichinasinthe. Kenako excreted ndi impsozo. Choncho, ngati kulakwila ntchito yawo anati kudzikundikira. Tizilombo theka moyo maola 1.5-4.5.

tsogolo

Medicine "Formetin" ntchito zochizira magulu ena a matenda. Ndicho, pamaso pa mtundu II shuga, ndi milandu kunenepa ndi zovuta pamene zakudya si kuthandiza kusunga shuga zachilendo, ngakhale limodzi ndi sulfonylurea a. Wogwira ndi "Formetin" chifukwa kuwonda.

Kodi kutenga?

Mlingo wa dokotalayo akunena amasankha, zochokera kuchuluka kwa shuga m'magazi. Dongosolo Oral m'pofunika kusonyeza pambuyo chakudya, kumwa ndi yambiri ya madzi ndi kuvumbula Machining piritsi. Monga tanenera pamwambapa, mlingo Kwalamulidwa malinga ndi zomwe zili shuga m'magazi. Umayamba ndi osachepera kuchuluka - 0,5 ga kapena 0,85 ga patsiku. masiku awiri pambuyo kuyambira chithandizo ndi mankhwala wakhala zili azilandira metformin m'magazi. Optionally, pang'onopang'ono akawawonjezere mlingo mpaka mtengo pazipita. Ndi lofanana magalamu 3.

Popeza achikulire kawirikawiri anati chitukuko cha acidosis lactic, iwo mlingo wa mankhwalawa pazipita tsiku la 1 g kuchuluka kwa mankhwala nazonso yafupika kuphwanya kagayidwe, pofuna kupewa sayanjana, amene kumaonekera mwa mawonekedwe a totupa pakhungu, ndi zina zotheka zochitika chowawa, zomwe zafotokozeredwa pansipa.

contraindications

Pankhani imeneyi, pali mfundo zina zabwino zambiri. Mankhwala "Formetin" malangizo ntchito chomwe chili mu nkhani iyi, ndi contraindicated mu kukhalapo kwa:

• Ashuga ketoacidosis, precoma, chikomokere.
• Aakulu chakhungu aimpso magwiridwe.
• Mtima ndi kupuma kulephera.
• Pachimake gawo la infarction m'mnyewa wamtima.
• Madzi m'thupi.
• Matenda uchidakwa ndi zinthu zina zimene zingachititse mawonetseredwe kukhala lactic acidosis.
• Pachimake sitiroko.
• Mimba ndi yoyamwitsa.
• Hypersensitivity kuti srudstvu izi.
• Opaleshoni kapena choipa, pamene insulin zakonzedwa.
• Aakulu opatsirana matenda.
• matenda zinchito chiwindi.
• Pachimake mowa poizoni.
• Lactic acidosis (kuphatikizapo mbiri).
• Hypocaloric zakudya (zosakwana 1000 kcal. Per tsiku).
• Adioizotopnyh kapena maphunziro radiographic, utsogoleli wa mtundu mankhwala iodide.

Amagwiritsidwanso osavomerezeka ntchito mankhwala "Formetin" anthu oposa zaka makumi asanu, kugwira ntchito zolemetsa. Kuyambira mu nkhani iyi, iwo ali pangozi yaikulu ya kudwala lactic acidosis kuchuluka.

mbali zotsatira

Nthawi zizindikiro ngati zosasangalatsa monga "zachitsulo" kukoma pa kamwa, kusanza, kutsekula m'mimba, flatulence, kusafuna kudya amafuna discontinuation wa ntchito mankhwala ndi kutumiza nthawi yomweyo katswiri. Yaitali ntchito mankhwala amachititsa zikusokoneza kapena kutha kwathunthu kwa madyedwe a vitamini _B12, imbaenda kudzikundikira mu thupi la inawo, kuchititsa kuperewera kwa vitamini. Nthawi zina, kukhala n'zosiyana - megaloblastic The magazi m'thupi _{12 patalipatali.} Ngati yosayenera kutumikiridwa mlingo hypoglycemia zotheka. Mukhozanso kuona thupi lawo siligwirizana monga zotupa pa khungu. Choncho, mankhwala "Formetin" ndemanga imene pa moyenera ake mu ntchito zosiyanasiyana, adzasankhidwa yekha ndi dokotala nawo.

Kusamala

Mbali yofunika kumatanthauza i kasungidwe zofunika mankhwala "Formetina" mu thupi ndi zotsatira za izi.

Pofuna kupewa kudzikundikira acidosis lactic ndi kupewa metformin, m'pofunika kuti aziona zizindikiro za ntchito impso ndi mayesero kudziwa zili asidi lactic mu thupi nthawi zosachepera 2 pa chaka. Komanso, ngati muli kupweteka minofu ayenera retested.

Zotsatira za anati mankhwala pa kukhoza kuyendetsa njira ndi kuyendetsa galimoto

Pankhaniyi, monga pali mfundo zina zabwino. Impact "mphamvu Formetina 'ntchito makina ndi zoyendera chimachitika pokhapokha ngati ntchito limodzi ndi mankhwala okhudza njira ntchito zimene zimafuna liwiro mayankho ndi kuchuluka ndende. Nkofunika kudziwa.

Kugwiritsa mimba ndi yoyamwitsa

Kukonzekera "Formetin", malangizo ntchito a Yehova amene akambidwa m'bukuli, mavuto pa mwana wosabadwayo gulu «B» mwa FDA. Ali woyembekezera akhoza kulandira ndalama. Komabe, ntchito yake kokha nthawi zina. Ndicho - pamene zotsatira kuyembekezera kwa mankhwala awa adzamvanso upambana kupezeka pa choopsya ndi kuthekera kwa mwana wosabadwayo. Yeniyeni ndi mlandu maphunziro pa ntchito chida monga mankhwala "Formetin" kunachitidwa pa nthawi ya mimba. Pa nthawi yolandira chithandizo ayenera kusiya kuyamwitsa mwana mkaka. Mulimonsemo, muyenera kukaonana ndi dokotala wodziwa.

Mwanjira mankhwala

Metformin kumawonjezera mlingo wa shuga m'magazi. Izi zimaonekera makamaka ndi phwando munthawi yomweyo sanali steroidal mankhwala odana ndi yotupa, sulfonylurea ena ofanana ndi clofibrate, monoamine oxidase zoletsa, acarbose, insulin, gentamycin, cyclophosphamide, zoletsa wa angiotensin akatembenuka blockers enzyme ndi mtundu.

Pamene ntchito limodzi ndi mankhwala endocrine (kulera m'kamwa, corticosteroids, sympathomimetics wa epinephrine, mahomoni chithokomiro England, glucagon, thiazide ndi "kuzungulira" okodzetsa, opangidwa kuchokera phenothiazine, nicotinic opangidwa kuchokera acid) Mwina metformin hypoglycemic braking ndondomeko.

Ndi osakaniza chida monga mankhwala "Formetin" ndi "Tsimidinom" "nifedipine" kukula chiopsezo acidosis lactic, metformin inhibiting ndi excretion thupi. Ngati kuti anamuona pa ntchito mankhwala chidakwa, mu Vol. H. Mu zikuchokera mankhwala.

Cationic wothandizila (quinidine, amiloride, digoxin, procainamide, morphine, kwinini, vancomycin, ranitidine, triamterene) aumbike mwa tubules ndi, mopikisana a dongosolo la mayendedwe ndipo nthawi yaitali mankhwala achuluke mlingo wa ndende mankhwala kwa 60%.

ambiri osokoneza

Ambiri osokoneza "Formetinom" anatero pamene mukumwa magalamu 0,85 patsiku ndipo imautsa lactic acidosis. Komanso, mkulu zili metformin chifukwa cholephera impso.

Zizindikiro zoyambirira za acidosis lactic ndi kufooka kwa thupi lonse, bloating, kutentha otsika thupi, kupweteka kwa m'mimba ndi minofu m'munsi magazi, reflex bradyarrhythmia. Nthawi zina, pali mawonetseredwe pafupipafupi matenda kupuma, chizungulire, ndipo monga Motero, pali chitukuko cha chikomokere.

Pa pang'ono zizindikiro cha mankhwala osokoneza bongo ayenera kusiya ntchito mankhwala ndi dokotala kuti atsimikizire matenda a acidosis lactic. Jaji wa chinthu yogwira nthumwi acid lactic ku chamoyo adzakhala hemodialysis zikufanana ndi mankhwala symptomatic.

"Formetin": Anzawo

Pali zambiri chuma cha mtundu uwu. Analogues "Formetina" protrude formulations munali mu kapangidwe kake ndi mbali yaikulu ya metformin hydrochloride. Chitsanzo chimodzi cha mankhwala a alimi Russian, "Vero Metformin," "Gliformin", "metformin", "Metformin-Richter", ndi kunja - "Glucophage", "Glucophage" ndi "Glyukofazh Long" (France), "Lanzherin "(Slovakia)" Metfogamma "yosiyana Mlingo wa mankhwala yogwira 0,100, 0,500 ndi 0,850 ga (Germany).

Zokwaniritsa ndi mawu

Pa nkhani imeneyi, pali zinthu zina. Kukonzekera "Formetin" ndi amphamvu, choncho adzamasulidwa yekha ndi mankhwala ndipo amafuna kusunga firiji, patali ana ndi dzuwa malo. Alumali moyo izo - zaka 2.

mtengo wa

Mtengo pafupifupi kwa mankhwala "Formetin" walembedwa malingana ndi mlingo ku 59 rubles. 0.5 ga chithuza pa, 133 rubles. wa 0,85 ga ndi 232 rubles. pa 1 chaka

Pomaliza

takambiranazi zonse zikuphatikizapo zambiri zothandiza. Nditawerenga nkhani imeneyi, aliyense adzakhala kupeza yankho la funso la mmene 'Formetin "ndi zimene ali katundu.