Kukonzekera Digitalis: zizindikiro ndi zotsatirapo matenda mtima

Digitalis - mtundu wa zomera maluwa, amene ntchito ngati mankhwala kwa matenda a mtima.

About kardiotropnyh katundu wa maluwa kale kudziwika. Mu zoyambirira za m'ma XVIII, anayamba kukula mu Russia m'minda apothecary, ndipo kuyambira 1775, pamene iwo zinatuluka ntchito za British zachipatala Uayteringa, kukonzekera digitalis kuti kwambiri chinachitika mu mchitidwe wa mankhwala a matenda mtima.

Makhalidwe botanical a digitalis

Rhode Foxglove (Digitalis) - maluwa zomera ndi osatha banja plantaginaceae ndi inflorescences yaikulu ya thimbles ofanana ndi maluwa ndi wosakhwima makwinya masamba. Pachimake m'katikati mwa chilimwe (mapeto a June-July), zipatso - lopinda mabokosi dzira woboola pakati ndi mbewu yaing'ono bulauni. Total naperstyanok anafotokoza mitundu 36 amene ntchito mankhwala zolinga yekha 5: digitalis lanata (limafotokoza zipangizo), wofiirira, ciliated, ndi grandiflora dzimbiri.

Poyamba mankhwala digitalis lanata anali Tingafinye wa masamba a chaka yoyamba ndi yachiwiri. Panopa, asatayike digitalis glycosides analandira kuchokera kumadera mlengalenga wa zomera, Ndimatchetcha pamaso maluwa.

Onse chakupha foxglove, zikusonyeza kuti ambiri zinthu biologically yogwira ndipo amafuna kugwiritsa ntchito bwino.

Mankhwala zigawo ndi ntchito foxglove

Mankhwala Digitalis monga yogwira waukulu zosakaniza - glycosides mtima: digitoxin, gitoksin, digoxin, atsetildigoksin ndi ena ambiri, komanso organic zidulo, saponins, flavonoids.

Ambiri zigawo zikuluzikulu yogwira ntchito hydrolytic chiyambi sekondale, i.e. akamagwira enzymatic pogawanikana pamawere la tinthu mwachibadwa zikuchitika glycosides.

mankhwala digitalis ntchito zochizira matenda ambiri mtima, makamaka zokhudzana ndi kuwonongeka kwa zipangizo mtima ndi magazi:

1. Mtima kulephera ndi matenda osiyanasiyana organic nyumba mtima (kuphatikizapo ngati muyeso njira).
2. Matenda a mavavu mtima zikubweretsa decompensation.
3. Matenda fibrillation.
4. Kutupa ndi alibe wa minofu mtima.
5. Paroxysmal tachycardia mu amayi apakati.
6. Kukonzekera opaleshoni ya mtima.

Pamene kuyan'anila za mtima dongosolo conduction (chipika) ndi bradycardia digitalis glycosides sanagaŵiridwe.

Kodi mankhwala digitalis glycosides

Olekanitsidwa udzu digitalis glycosides zotsatira enieni a minofu mtima. Mu matenda a mtima, zotsatira za digitalis ntchito chiri motere:

• ndichepe mu kugunda kwa mtima;
• kuwonjezera m'mnyewa wamtima contractile mphamvu;
• kutalikitsa nthawi yosangalala kwa mtima (diastole).

Kukonzekera digitalis akhala bwino ntchito pa matenda a kulephera magazi pamene mtima sangathe kulimbana ndi kufalitsa zipangizo mwazi, umene kobvuta ndi edema ndi matenda trophic. Pankhaniyi, ndi mankhwala glycosidic akuyembekezeka:

• kuchuluka mtima linanena bungwe (kuchuluka kwa magazi akutuluka wa ventricles pa kuchepetsa);
• aluso Ndikudzikhuthula kwa ventricles pa systole;
• kuchepa kwa magazi buku kufalitsidwa mu zotengera, ndipo chotero, kuchepetsa kutupa;
• normalization wa kugunda kwa mtima tachycardia;
• mathamangitsidwe wa magazi pa kama mtima;
• kuwonjezera kamvekedwe mtima, amene anatsagana ndi kuwuka pang'ono magazi.

Digitalis kawopsedwe imfayo osafunika zotsatira zoyipa kusokonezeka pa mundawo m'mimba, mantha dongosolo, kusintha kugunda kwa mtima. Wosaloleka ntchito mankhwala si yoyenera, mankhwala kamwedwe dokotala amasankha yekha anapatsidwa mtima munthu.

Mankhwala kwa foxglove wamaonekedwe a nkhope yaubweya

"Tselanid" - mtima glycoside kanthu mofulumira amapangidwa mu mawonekedwe a miyala ndi njira jekeseni mtsempha. The zizindikiro zazikulu - magazi kulephera, tachycardia, matenda fibrillation.

"Digoxin" amakhala ndi kuwonjezeka mu contractility m'mnyewa wamtima, popanda kuphwanya makope inatsekeratu ndipo kumachepetsa kutupa chifukwa zotsatira diuretic. M'nsinga ndi pakamwa. Iwo anasonyeza kuti matenda aakulu magazi ndi pa kuukira kwa tachycardia paroxysmal mwadzidzidzi.

zotsatira achire kufika pazipita pambuyo nthawi imene mankhwala yogwira m'thupi anafika ndende zina. Pali zotsatira chokhala (kudzikundikira) chifukwa chakuti digitalis kukonzekera kuonekera pang'onopang'ono.