Mankhwala "allopurinol": ndemanga madokotala, zizindikiro, mavuto

Pakali pano, mankhwala "allopurinol" ndi zofunika (pulayimale ndi pathogenetically otsendereka) ndi mankhwala ogwiritsidwa ntchito pa matenda a matenda monga gout. Munthu aliyense pamaso panu n'kuyesa, kuyesera kupeza mfundo zothandiza kwambiri za izo. Choncho timapereka kuthana mwatsatanetsatane ndi pamene yemweyo ayenera kutsatira "Allopurinol". Reviews odwala ndi madokotala Adzaperekedwa ku nkhani yathu ndipo mudzadziwa kuti zimene kuopa pamene akumwabe mankhwala.

Pharmacological makhalidwe a mankhwala

"Allopurinol" amatanthauza kukonzekera gulu protivopodagricakih. Waukulu yogwira mankhwala - allopurinol ndi metabolite ake yogwira oksipurinola. Izi zotsatira pharmacodynamic chifukwa kuphwanya kaphatikizidwe asidi uric ndi zotsatira chitukuko urostaticheskogo. Izi n'kukumana ndi kuchepetsa ndende wake, kenako Kutha urate.

Chifukwa cha zabwino solubility "allopurinol" ali mkulu bioavailability. mankhwala bwino odzipereka ku lumen za m'mimba yaing'ono. M'mimba mwa kufalitsa zokhudza zonse asagwe. pamaso pa madzi a m'magazi yakula kwa theka la ola pambuyo boma ndi ndende pazipita anati pambuyo maola 1.5. Choncho, ndende pazipita ndi metabolite wa allopurinol - oksipurinola anati maola atatu pambuyo makonzedwe m'kamwa.

Mankhwala ali yaitali theka moyo ndi chifukwa amatha cumulation. Odwala pa chiyambi cha mankhwala, pali kochulukira ndende ya mankhwala limakhazikitsa pambuyo masabata wina kwa awiri a mankhwala. Chifukwa cha yaitali Kupha "Allopurinol" (ndemanga madokotala titsimikizire kuti) ali osavomerezeka ntchito anthu ndi kulephera impso. Odwala ndi anasunga aimpso excretory ntchito cumulation si anati.

"Allopurinol": zikuonetsa ntchito

Reviews madokotala kupereka izi amanena mankhwala kuti ndi yabwino kwambiri ndipo wolungama milandu hyperuricemia (mpweya wambiri wa asidi uric pa wagawo buku la magazi) pa:

• gouty nyamakazi (gout);
• matenda urate urogenital (nephropathy, urolithiasis);
• matenda oncological mwazi;
• anomalies kobadwa nako a dongosolo enzyme.

Nthawi zina, zotheka kugwiritsa ntchito mankhwala zochizira ana urate nephropathy, amene anaonekera pa maziko a mankhwala khansa matenda kobadwa nako kugwirizana ndi mkhutu kagayidwe asidi uric, sekondale hyperuricemia chiyambi osiyana.

Features mankhwala

"Allopurinol" mapiritsi (ndemanga anachenjeza kumvera kwambiri ndi malangizo a mankhwala) atengedwa pambuyo chakudya, iwo si zosatheka kutafuna, koma kumwa wawo wonse ndi kumwa osachepera kapu ya madzi ofunda.

Anthu kutenga mankhwala, nthawi zonse muyenera kuwunika chakudya, ndipo mu nkhani ya Kusokera mwa zakudya zofunika kusintha mlingo wake, koma kuyang'aniridwa ndi katswiri nawo.

Mlingo zofunika kuona 'allopurinol "mankhwala anatsimikiza malinga ndi zomwe zili asidi uric mu mtsempha wa magazi. Childs, izo ranges ku mg ndi 100 mpaka 300 pa nthawi "allopurinol" kukonzekera wina. Reviews odwala ndi madokotala zokhudza dosing ichi zabwino, monga mankhwala akutengedwa kamodzi kokha patsiku.

Gout mankhwala kuyamba ndi kuika 100 mg wa mankhwala kamodzi pa tsiku. Mu nkhani ya kupanda efficacy ndi osauka kutsitsa uric asidi mlingo pang'ono ndi pang'ono kuchuluka (by 100 mg lililonse masabata awiri kapena atatu), zikubweretsa ogwira achire zasayansi pansi pa ulamuliro wa milingo uric acid. Zikatero, mlingo pafupifupi ndipo anayamba kukonza mlingo ranges 200 400 mg, koma zina, mlingo kungakhale kwa 800 mg. Mu nkhani iyi, lagawidwa kangapo patsiku.

Poika mankhwala odwala insufficiency aimpso ayenera kuganizira chilolezo creatinine.

Contraindications kuti "Allopurinol" chikhazikitso

mankhwala ali contraindicated odwala ndi kulephera aakulu aimpso, komanso pakati ndi lactating. Amagwiritsidwanso osavomerezeka chifukwa mankhwala odwala ndi sayanjana kapena hypersensitivity kwa zigawo chimodzi kapena zingapo lokonzekera. Iwo analetsedwa kugwiritsa ntchito mankhwala odwala ndi milingo wammalire wa asidi uric mu madzi a m'magazi, chifukwa cha lawo Ndikulichepetsa ndi kupambana chingapezeke mwa kusintha zakudya.

"Allopurinol": mavuto

Reviews cha odwala amene ntchito mankhwala kwa nthawi yoyamba, zikusonyeza kuti nthawi zambiri N'kutheka exacerbation ndi kuchuluka zizindikiro za gout ndi zikamera kuukira otchedwa. Koma izi chodabwitsa yochepa, ndipo si koyenera kuti mantha zokwanira kusiya mankhwala. Koma mu nkhani ya totupa aliyense, kusapeza kapena kusowa zizindikiro zoyambirira muyenera yomweyo kudziwitsa dokotala. Mu njira imeneyi "Allopurinol" Tiyenera kumukhalitsa yomweyo, ndipo mofulumira zizindikiro katswiri akhoza kachiwiri perekani mankhwala, koma kuti mlingo wamng'ono (50 mg). Chikuonetseratu iyenera kuchitikira kuyang'aniridwa pafupi kwa dokotala kupezeka ndi chipinda a.

Mwa zochita chowawa ya ubongo ndi ntchito apamwamba maganizo angayambitse maganizo. Pa gawo la chitukuko cha kupondereza fupa dongosolo mafuta hematopoietic sikawirikawiri anaona ndi zosayembekezereka wa thrombocytopenia, aplastic magazi m'thupi.

Pamene kulandira mankhwala akhoza kuyamba matenda kagayidwe kachakudya monga matenda a shuga, kofunikira kwambiri zidulo mafuta mu madzi a m'magazi.

Cardio-mtima dongosolo angathe oopsa, bradycardia.

Pafupipafupi zosiyanasiyana chokhwima kwa mankhwala ndi kuchuluka pamaso pa kulephera aimpso wodwalayo.

mawonekedwe kumasulidwa ndi mlingo

"Allopurinol" likupezeka piritsi mawonekedwe (ma PC 30 kapena 50. Pa phukusi) pa mlingo 100 kapena 300 mg wa yogwira pophika pa piritsi. Mu msika zoweta pali "Allopurinol Sandoz 300". Ndemanga za izo zabwino, monga mankhwala mlingo ulipo kamodzi kokha patsiku, pafupifupi negates n'zotheka kuphonya phwando ya mankhwala.

Poyizoni ndi mankhwala ambiri osokoneza bongo

Poyizoni kawirikawiri, koma zochitika pali milandu mlingo umodzi wa magalamu 20 ya mankhwala. Pankhaniyi, inu zizindikiro zotsatirazi: chizungulire, kusanza, kutsekula m'mimba. Mu insufficiency aimpso, ndi yoyendetsa mosalekeza kwa mlingo waukulu wa mankhwala amene asunga matenda kuledzera mu mawonekedwe a malungo, matenda a chiwindi, kulephera pachimake aimpso.

Chithandizo cha poyizoni pachimake ndipo ambiri osokoneza, symptomatic, umalimbana mofulumira kuwonongedwa kwa mankhwala ndi thupi. No adakalibe yeniyeni. Pakuti mofulumira excretion wa mankhwala m'thupi njira dialysis ogwira detoxification.

Reviews

Popeza chakuti nthawi kudzikundikira mankhwala magazi (pa ndende okwanira kupereka kanthu achire) ndi avareji ya mlungu umodzi, odwala matenda gout, iyenera kugwiritsidwa ntchito pafupifupi moyo "allopurinol". Reviews madokotala ndi lomveka: mankhwala watsimikizira lokha bwino. Koma uwu si "chozizwitsa mapiritsi" ukhoza chakumwa ndi kuyiwala za matendawo. Gout - ndi m'malo njira ya moyo, osati matenda. Koma ndi "Allopurinol" kumathandiza kuchepetsa mlingo wa asidi lactic ndi kuteteza aggravation ya matenda ndiponso kupitilira wake zina.

Kumbali ya mayiko, kopita "Allopurinol" mankhwala ayankhe madokotala ndi zabwino, chifukwa nthawi zambiri wodwala ayenera kumwedwa mankhwala kamodzi tsiku lililonse. Izi minimizes Mwina kusowa phwando medicament ndi, choncho kumawonjezera dzuwa la chithandizocho.

Pomaliza

Choncho, mankhwala chachikulu gout - "Allopurinol". akatswiri Reviews ndi odwala, izi zikutanthauza kutenga, zabwino, ndipo umenewu ndi umboni Mwachangu wa medicament ndi mankhwala a Gout ndi uric matenda asidi kagayidwe. Chifukwa cha ntchito ya mankhwala, chiwerengero chachikulu cha odwala akhale ndi chiyembekezo kuchepetsa mavuto a shuga.