Mankhwala 'Pronoran'. Malangizo ogwiritsidwa ntchito

Mankhwalawa akuti "Pronoran" (analogi a mankhwala monga "Tasmar", "Selegiline", "Parkon" ndi ena) amapezeka m'gulu la anti-Parkinsonics. Chogwiritsidwa ntchito ndi pyribedil. Mankhwalawa amapezeka mu mawonekedwe apiritsi.

Pambuyo kumeza, chogwiritsira ntchito chikugwiritsidwa ntchito mofulumira kuchokera kumagetsi. Mankhwalawa amadziwika patapita ola limodzi. Kutuluka kwa pulogalamu ya "Pronoran" pang'onopang'ono kumatulutsa pang'ono pang'onopang'ono. Mankhwalawa amatha maola makumi awiri ndi anayi.

Pogwiritsa ntchito mankhwala akuti "Pronoran", malangizo omwe amagwiritsa ntchito amasonyeza kuti ali ndi mphamvu yogwiritsira ntchito vasodilating (kuwonjezera kugawira magazi m'ziwiya m'magulu a m'munsi). Mankhwalawa amachititsa kuti dopaminergic ayambe kugwiritsira ntchito magetsi panthawi imene akugona komanso akamadzuka, komanso zimakhudza ntchito zosiyanasiyana zomwe zimayendetsedwa ndi dopamine.

Malangizo a mankhwala akuti "Pronoran" omwe amagwiritsa ntchito amalimbikitsa matenda a Parkinson ngati mankhwala osokoneza bongo omwe amawopsya, kapena ngati mbali ya mankhwala ovuta (kachiwiri kapena kumayambiriro kwa matendawa mwa maonekedwe omwe amatsagana ndi chivomezi). Mankhwalawa amaperekedwa monga chithandizo chowonjezereka cha matenda omwe amachititsa kuti asamangoganizira za matenda okalamba (kuphatikizapo kukumbukira ndi kusamvana). Zisonyezo zimaphatikizapo zizindikiro za matenda opatsirana a zachilengedwe (kuphatikizapo kuchepetsa kuwona zinthu, kuchepetsa kusiyana, kuponderezera masomphenya). Monga mankhwala ena owonjezera, malangizo akuti "Pronoran" omwe amagwiritsidwa ntchito amagwiritsidwa ntchito potsatsa ndondomeko yomwe ikugwirizana ndi kuthetsa zilonda za m'munsi.

Palibe mankhwala omwe akulamulidwa kuti agwe, hypersensitivity kukhala zigawo zikuluzikulu, matenda osokoneza bongo ndi matenda ena a mtima. Mankhwala akuti "Pronoran" omwe amagwiritsidwa ntchito kuti asagwiritsidwe ntchito samalimbikitsa kutenga nthawi yomweyo ndi mankhwala osokoneza bongo, omwe ali ndi mankhwala amphamvu kwambiri (kupatula mankhwala "Clozapine").

Chifukwa cha kusowa kwa chidziwitso chotsimikizirika cha momwe ntchito ndi mankhwala amachitira panthawi yomwe ali ndi mimba komanso lactation, sichidalembedwe kwa amayi omwe ali ndi pakati komanso omwe akulera.

Kutenga mankhwala "Pronoran" kungayambitse kupweteka, kusanza, kunyoza. Mawonetseredwe ameneŵa amachotsedwa, kawirikawiri pambuyo pa kusintha kwa mlingo. Nthawi zina, mankhwalawa angayambe kugona, matenda osokonezeka maganizo (chisokonezo, nkhawa). Monga lamulo, zizindikiro zimachotsedwa pambuyo poti mankhwalawa achotsedwa. Kawirikawiri pangakhale phindu la BP kapena orthostatic hypotension, zomwe sizikuchitidwa. Mankhwala "Pronoran" (ndemanga za odwala ndi akatswiri amatsimikizira izi) amasamutsidwa nthawi zambiri bwino.

Mankhwala amauzidwa atatha kudya, mkati. Mapiritsi sayenera kuphwanyidwa. Mankhwalawa amamezedwa mokwanira, amafinyidwa pamtingo wokwanira ndi madzi.

Zonsezi (kupatulapo matenda a Parkinson), mlingo woyenera ndi mlingo umodzi (50 milligrams). Tengani mankhwala kamodzi patsiku. Ngati kuli kofunikira (monga kuvomerezedwa ndi dokotala), amaloledwa kuwonjezera mlingo wa theka (ma milligram makumi asanu pa tsiku).

Monga monotherapy ya matenda a Parkinson, 150-250 milligrams (mapiritsi atatu kapena asanu) tsiku ndi tsiku amalembedwa. Monga gawo la mankhwala osakaniza, mlingo wa mankhwala "Pronoran" wafupika kukhala 100-150 milligrams pa tsiku (mapiritsi awiri kapena atatu).

Ngati wodwala ali ndi matenda oopsa, mankhwala ophera antipersitermal treatment amalembedwa nthawi yomweyo ndi kumwa mankhwala.

Kugwiritsira ntchito mankhwala "Pronoran" kuyenera kuyang'aniridwa ndi katswiri.