Mankhwala "Topamax": mayankho a odwala ndi madokotala

Kugwiritsa ngati mankhwala, monga "Topamax"? Reviews madokotala ndi odwala Adzaperekedwa pansipa. Komanso, adzaphunzilanso pa zimene amagwira ntchito mankhwala ayenera kugwiritsidwa ntchito ndi zomwe katundu achire ndi yodziwika.

The zikuchokera, mawonekedwe

Kodi maonekedwe akugulitsa mankhwala "Topamax"? Umboni amanena kuti chida izi zikhoza kugulidwa mu mawonekedwe a makapisozi gelatin, olimba woyera.

The yogwira pophika mankhwala ndi topiramate. Komanso mu kapangidwe kake zikuphatikizapo zotsatirazi zinthu wothandiza: grits shuga, povidone, ndi mapadi nthochi.

The kugulitsa mankhwala "Topamax" (ndemanga madokotala za izo ndi osokoneza kwambiri khalidwe) amachokera ku mabotolo pulasitiki ndi mapaketi a makatoni motero.

Zochita za mankhwala

Kodi makapisozi "Topamax"? Reviews mwasonyeza kuti mankhwala antiepileptic limene limafotokoza kuti fructose. opaleshoni ake amafotokozera akhoza ziletsa njira sodium, komanso amachepetsa mphamvu ya mobwerezabwereza Zoyenereza kanthu mu depolarization yaitali makoma ubongo.

Phwando lipoti njira kumawonjezera ntchito asidi γ-aminobutyric mu ulemu wa mitundu ina ya GABA-maselo. Komanso, yogwira mankhwala angathe kutsekereza kutsegula kwa kainate kuti glutamate zolandilira, ndi zonse ntchito GABA-maselo. Chotero zotsatira achire ndi mlingo okhudza mankhwala ndipo anati kwa tanthauzo lake mu magazi 1-205 micromolar.

katundu Kodi zina khalidwe la mankhwala "Topamax"? Reviews amanena kuti pophika waukulu akhoza ziletsa ntchito carbonic anhydrase chiwerengero cha isomers. Tikumbukenso kuti azikhala ndi katundu pharmacological mankhwala amakhala otsika kwambiri zoletsa carbonic anhydrase, mwachitsanzo acetazolamide. Chotero ntchito mankhwala si yaikulu zikuluzikulu za ntchito yake antiepileptic.

Kayendedwe makhalidwe lokonzekera

Kaya mankhwala odzipereka "Topamax"? Reviews kuti atakhala mankhwala yogwira limatanthauza mofulumira kwambiri odzipereka kwa intestine lapansi. Choncho bioavailability wa topiramate ukufika 81%. Kudya chakudya alibe mphamvu pa chizindikiro ichi.

KUMANGA za yogwira mankhwala chigawo zonsezo plasma ukufika 13-16%.

Kuti tikwaniritse mgwirizano mu anthu ndi ntchito yachibadwa impso angafunike za 4-8 masiku. Transformation amaloŵamo 20% ya ndalama mlingo analandira. Izi ndipamene metabolites asanu ndi limodzi (anafooka).

Topiramate, komanso ena ofanana zake zonse linachokera ndi impsozo. Nthawi zikutanthauza awo theka moyo maola 22.

Zikuonetsa kulandira makapisozi mankhwala

Nthawi zina, odwala Kwalamulidwa mankhwala "Topamax"? Reviews la migraine ndi zabwino zokha. Ankaona kukonzekera ntchito osati zochizira matenda anati ubongo, komanso kupewa ake.

Iwo ayenera kukumbukira kuti chida ichi bwino unaonekera mwa khunyu. Izo ntchito monotherapy ya ana kwa zaka ziwiri ndi akulu. Komanso, "Topamax" kawirikawiri analimbikitsa kutenga anthu ndi kumene matenda a khunyu.

Monga mbali ya mankhwala zovuta za mankhwala akusonyeza ana kwa odwala zaka ziwiri ndi wamkulu ndi tsankho kapena zimandilimbikitsa-clonic khunyu zowombetsa mkota, komanso zochizira matenda Lennox-Gastaut.

Contraindications kulandira makapisozi mankhwala

Nthawi zina, simungathe kutenga makapisozi "Topamax"? Ndemanga (ana osaposera zaka ziwiri za mankhwala ali contraindicated) limati amaona kuti mankhwala si ntchito odwala hypersensitive kwa zigawo zake.

Ndi kusamala kwambiri ayenera kugwiritsidwa ntchito mankhwalawa ndi kulephera chiwindi, nefrourolitiaze, kulephera aimpso ndi hypercalciuria.

dosing

Landirani mankhwala "Topamax" ayenera kuperekedwa pakamwa. makapisozi akhoza kuwameza lonse, ndipo n'zotheka kusakaniza zili ndi pang'ono chakudya zofewa.

Pakuti ulamuliro wa khunyu khunyu mankhwala osavomerezeka kuyamba ndi otsika phwando Mlingo medicament, kenako titrated kwa imayenera awo.

Pamene zimandilimbikitsa-clonic khunyu ndipo matenda a Lennox-Gastaut osachepera ogwira mlingo wa mankhwala ndi 200 mg pa tsiku. Nthawi zina, odwala kulandira pazipita tsiku mlingo akhoza wasonyeza wofanana 1600 mg.

Ana zaka ziwiri analimbikitsa mlingo tsiku 5-9 mg wa pa makilogalamu thupi.

Kodi kuchitira mankhwala ayenera kumwedwa ndi khunyu? Monotherapy akulu zotchulidwa 25 mg tsiku lililonse kwa sabata imodzi. Komanso, chiwerengero ichi ndi chinawonjezeka ndi 25-50 mg wa lililonse 1-2 masabata.

Analimbikitsa Mlingo monotherapy a khunyu ana siyana mu osiyanasiyana 100-400 mg wa pa tsiku.

Pakuti kupewa migraine mankhwala ayenera kutenga 50 mg kawiri pa tsiku. Ngati ndi kotheka, mlingo akhoza ziwonjezeke (mpaka isanayambike zotsatira matenda).

mbali-zotsatira za khalidwe

Ankaona mankhwala zingachititse zosiyanasiyana mbali. Nthawi zambiri akuwonetseredwa ali motere:

• kusinza, kufooka, chizungulire, kenaka utentha mamba, mphwayi, apraxia, maganizo nthenda, amnesia, mkhutu kugwirizana, dystonia;
• chisokonezo, kulira, maganizo pang'onopang'ono, kuyerekezera zinthu m'maganizo, maganizo, utachepa libido, euphoric maganizo, zochita aukali;
• anorexia, kapamba, gastritis, flatulence, zizindikiro dyspeptic;
• spasms, omangana, kutupa m'malo olumikizirana mafupa ndi;
• unilateral khungu, presbyopia, conjunctival edema, ndi ena.

Medicament "Topamax": Ndemanga

Khunyu - matenda zofunika kwambiri zimene mankhwala wapatsidwa mwachikondi. Malinga ndi mawu a madokotala ndi matenda mankhwala si tizisonyeza okwanira achire lapamwamba. Komanso kulimbikitsa kuchuluka kwa zochita phwando mbali, kuphatikizapo mbali ya ubongo ndi psyche.

Monga odwala, iwo amanena kuti tolerability osauka mankhwala. Ndichifukwa chake ambiri mwa iwo amakonda kugwiritsa ntchito kwambiri yakusankha ndalama iwo dokotala akuonetsa.

Sitingathe kunena kuti mankhwala funso chimagwiritsidwa ntchito ndi odwala ambiri monga njira kuonda. Komabe, akatswiri amanena kuti pamene mukumwa makapisozi "Topamax" zolinga izi ziyenera kuganizira kawopsedwe ake okwezeka.