NSAIDs - izi ndi zimene mankhwala? NSAIDs: mawu olembedwa. A mbadwo watsopano wa NSAIDs

Chidule NSAIDs - Kodi amene kukuuzani chilichonse? Ngati ayi, ife amati ochepa wotsegula M'maso mwanga ndi kuphunzira oimira m'makalata anayi mwachinsinsi. Werengani nkhani - ndi chirichonse mwangwiro bwino. Tikukhulupirira kuti si nkhani chabe, komanso zosangalatsa!

NSAIDs - mawu olembedwa

Sitidzakhala yaitali otopa Owerenga mu mdima. NSAID amayimira sanali steroidal mankhwala odana ndi yotupa - mankhwala mu nthawi yathu chotchuka kwambiri ndi otchuka, kuti amatha imodzi kuthetsa ululu ndi kutupa m'malo olumikizirana mafupa mu ziwalo zosiyanasiyana za thupi ... Ngati mpaka tsopano inu simunayambe anayambika kufunika NSAID mankhwala - ichi tinganene kuti pafupifupi chozizwitsa. Inu - mmodzi wa luckies zina, kwenikweni, thanzi lanu akhoza amasirira!

Patsogolo funso lotsatira ndipo pomwepo anatiuza za tanthauzo la mawu akuti "si steroidal". Izi zikutanthauza kuti mankhwala m'thupi, mwachitsanzo, Iwo lilibe mu dongosolo lake mahomoni iliyonse. Ndipo ndi chabwino kwambiri, chifukwa ife tonse tikudziwa mmene kungakhale sizimadziwika ndi oopsa mahomoni.

The NSAIDs otchuka

Ngati mukuganiza kuti NSAIDs - mankhwala amene maina kawirikawiri analankhula mu moyo wa tsiku ndi tsiku, ndiye inu mukulakwitsa. anthu ambiri sadziwa n'komwe kangati tili ntchito sanali steroidal odana ndi yotupa mankhwala mankhwala matenda osiyanasiyana kuti ayende mtundu wa anthu kuyambira Kuchotsedwa kwa Adamu ndi Hava paradaiso Kusch. Onani ndandanda wa ndalama zimenezi, ndithu ena mwa iwo ali mu mankhwala kwanu nduna. Kotero, kuti NSAIDs monga mankhwala monga:

• "Aspirin".
• "Amidopyrine".
• "Analgin".
• "Piroxicam".
• "Bystrumgel".
• "Diclofenac".
• "Ketoprofen".
• "Indomethacin".
• "Ketorol".
• "Naproxen".
• "Ketorolac".
• "Flurbiprofen".
• "Voltarengel".
• "Nimesil".
• "Diclofenac".
• "Ibuprofen".
• "Indopan".
• "Ipren".
• "Upsarin UPSA".
• "Ketanov".
• "Mesulid".
• "Movalis".
• "Nise".
• "Nurofen".
• "Ortofen".
• "Thrombotic ACC".
• "Ultrafen".
• "Fastum".
• "Finalgel".

Inde, mankhwala onse NSAID. Mndandanda kunapezeka, ngakhale lalikulu, koma, ndithudi, ali kutali wathunthu. Ndipo Komabe amapereka lingaliro la zosiyanasiyana sanali steroidal mankhwala amakono odana ndi yotupa.

A pang'ono mabuku a mbiri yakale

Woyamba mankhwala wosazindikira NSAID akhala kudziwika kwa anthu kuchokera kalelo. Mwachitsanzo, ku Iguputo, kuchotsa kutentha ndi ululu anali chimagwiritsidwa ntchito msondodzi makungwa - gwero chilengedwe cha salicylates ndi mmodzi wa sanali steroidal mankhwala oyamba odana ndi yotupa. Ndipo m'masiku amenewo madokotala ankachitira odwala awo akudwala zowawa olowa ndi malungo, decoction wa mchisu, ndimu mankhwala - iwo muli salicylic.

Cha m'ma 19 m'ma chinayamba zimapangidwira, amene anapereka kutsogolera chitukuko cha mankhwala. Ndiye maphunziro akhala akufufuza nyimbo mankhwala oyamba anachokera ku zipangizo masamba yaiwisi. Net salicin ku msondodzi makungwa anali apanga mu 1828 - anali sitepe yoyamba kwa kupanga bwino kuti ife tonse "Aspirin".

Koma chidzakhala kwa zaka zambirimbiri kafukufuku musanasankhe mankhwala adzabadwa. chochitika chachikulu chinachitika mu 1899. Madokotala ndi odwala awo mofulumira anayamikira ubwino wa mankhwala atsopano. Mu 1925, pamene Europe anakomoka mliri lowopsya la fuluwenza, "Aspirin" anakhala Mpulumutsi kwa anthu ambiri. Mu 1950, sanali steroidal odana ndi yotupa mankhwala anali mu Guinness Book of Records ngati mankhwala ochititsa ndi buku chachikulu cha malonda. Chabwino, ndiye mankhwala analengedwa ndi nonsteroidal odana ndi yotupa mankhwala ena (NSAIDs).

Kodi matenda odana ndi yotupa mankhwala si steroidal ntchito

Osiyanasiyana ntchito ndi NSAIDs lonse. Iwo zimathandiza kwambiri pa kusintha kwa matenda onse pachimake ndi aakulu limodzi ndi ululu ndi kutupa. masiku awa ali kugwedezeka lathunthu la kafukufuku wa efficacy wa mankhwala pa matenda a matenda a mtima ndi mtima. Popeza kuti iwo angagwiritsidwe ntchito kupweteka msana masiku ano amadziwika pafupifupi onse (NSAIDs osteochondrosis ndi enieni chipulumutso).

Pano pali mndandanda wa zinthu matenda, kukachitika kuti umaonetsa ntchito NSAIDs osiyana:

• Malungo.
• Mutu, kupweteka kwa mutu.
• Aimpso colic.
• Nyamakazi.
• Gout.
• Arthrosis.
• Nyamakazi.
• Dysmenorrhea.
• arthropathies yotupa (psoriatic nyamakazi, ankylosing spondylitis, syndrome Reiter a).
• Postoperative ululu syndrome.
• Ululu syndrome ofatsa zoopsa lochepa kusintha zosiyanasiyana yotupa.

Gulu la NSAIDs malinga ndi dongosolo lawo mankhwala

Ndi kuwerenga nkhani ino, tawona kale kuti mankhwala si steroidal odana ndi yotupa zambiri. Kuyenda mwa iwo osachepera pang'ono bwino, tiyeni titenge gulu la zinthu zimenezi. Choyamba, iwo akhoza kugawidwa motere: Gulu - gulu la acid ndi NSAIDs - zotumphukira sanali acid.

Zoyambazo monga:

- salicylates (athanso kukumbukira "Aspirin").

- phenylacetic opangidwa kuchokera ku asidi ( "Aceclofenac," "Diclofenac" neri Al.).

- pyrazolidine (metamizole sodium, amadziwika kuti ambiri a ife monga "Analgin" "phenylbutazone, etc.).

- oxicams ( "tenoxicam," "Meloxicam", "piroxicam" "tenoxicam").

- The opangidwa kuchokera ku asidi indole acetic ( "Sulindac", "Indomethacin", etc.).

- otumphukira asidi propionic ( "Ibuprofen", etc ...).

Gulu lachiwiri - izi:

- otumphukira sulfonamide ( "Celecoxib", "Nimesulide", "Rofecoxib").

- alkanones ( "nabumetone").

Gulu la anthu omwe sanali steroidal mankhwala odana ndi yotupa kwa mogwira awo

Ntchito NSAIDs pamene kuchitira osteochondrosis ndi matenda ena olowa angathe kwenikweni ntchito zodabwitsa. Koma, mwatsoka, si mankhwala onse ndi ofanana wogwira awo. atsogoleri mtheradi tinganene kuti pakati pawo:

• "Diclofenac".
• "Ketoprofen".
• "Indomethacin".
• "Flurbiprofen".
• "Ibuprofen" ndi zina mankhwala ena.

mankhwala zili akhoza kutchulidwa m'munsi; T. e. zochokera iwo akhoza kukulitsa kulowa mankhwala maukonde NSAIDs latsopano, koma pansi dzina osiyana, ndipo anasintha zambiri pa mtengo wapamwamba. Pofuna kuwononga ndalama yanu pachabe, wophunzira m'mutu wotsatira. mfundo izo, zidzakuthandizani kuti kuonedwa ndi kusankha.

Choti posankha mankhwala ndi

NSAIDs - ichi, ku mbali yaikulu, mankhwala kwambiri masiku ano, koma kubwera kwa mankhwala, ndi bwino kudziwa ena mokoma lapansi. Kodi? Koma kuwerenga!

Mwachitsanzo, kusankha kuti ndi bwino kugula "diclofenac", "Ortofen" kapena "Voltaren". Ndipo inu kuyesa kufunsira kwa pharmacist, amene mankhwala bwino. Ambiri mwina, mudzakhala analangiza amene ali okwera mtengo kwambiri. Koma kuti zikuchokera mankhwala awa ali pafupifupi zofanana. A kusiyana mu maina chifukwa amapangidwa ndi Makampani osiyana, makolo ndi zotetezedwa zosiyana Chrixitu. N'chimodzimodzinso anati, mwachitsanzo, "indomethacin" ndi "indomethacin" kapena "ibuprofen" ndi "Brufene" ndi zina zotero. D.

Kumvetsa chisokonezo, nthawi zonse yang'anitsitsani pa ma CD, pakuti ayenera kupatsidwa yaikulu yogwira mankhwala mankhwala. inalembedwa, izo Mosakayikira zilembo zazing'ono.

Koma si onse. Kwenikweni, si mophweka! NSAID-analogue mankhwala ndi bwino inu mwadzidzidzi kuyambitsa matupi awo sagwirizana anachita kapena mankhwalawo kuti asanakumanepo anati. Chavuta? chifukwa angagone mu zina zowonjezera, amene, kumene, pa ma CD kanthu linalembedwa. Chotero, tiyenera kuphunzira kwambiri ndi malangizo.

Chifukwa china zotsatira zosiyana za mankhwala analogi - kusiyana mlingo. anthu osadziwa zambiri musati mupereke chidwi chirichonse kwa izo, koma sizinathandize. Ndipotu, wamfupi tabletochki anyamula "kavalo" mlingo wa mankhwala yogwira. Tikawonetsetsa mapiritsi kapena makapisozi yaikulu zimachitika kuti zigwirizana fillers ndi mochuluka momwe 90 peresenti.

Nthawi zina wothandizila ndi zilipo komanso mu mawonekedwe retardirovannoy, T. E. Monga mankhwala anawonjezera (yaitali) kanthu. Mbali yofunika ya mankhwala ndi luso limbikirani pang'onopang'ono, moti mmene ukhoza tsiku lonse. kukonzekera wotereyu sayenera kumwa nthawi 3 kapena 4 pa tsiku, zokwanira kukhala mlingo umodzi. Mbali imeneyi ya mankhwala ayenera anasonyeza pa ma CD kapena udindo. Mwachitsanzo, "Voltaren" mu mawonekedwe kupepera amatchedwa "Voltaren achigonjetse."

List of analogues wa mankhwala odziwika

Ife kufalitsa izi wakunyengeza pepala kakang'ono mu chiyembekezo kuti adzakuthandizani bwino kuyenda zosiyanasiyana mankhwala phukusi. Tiyerekeze yomweyo amafuna NSAIDs mogwira nyamakazi kuthetsa ululu wosaneneka. Anatenga pepala wakunyengeza ndi kuwerenga mndandanda zotsatirazi:

- analogi "Diclofenac", kupatula kale "Voltaren" ndi "ortofen" ndi "Diklofen", "Dikloran", "Diklonak", "Rapten", "Diklobene", "Artrozan", "Naklofen".

- "Indomethacin" wogulitsidwa zopangidwa monga "Indomin", "Indotard", "indomethacin", "Revmatin", "Indobene", "Inteban".

- analogues "Feldene" "Erazon", "pyroxene", "Roksik", "pyroxene".

- analogues "Ketoprofen", "Flexi", "Profenid", "Ketonal", "Artrozilen", "Knavon".

- A otchuka ndi yotchipa "Ibuprofen" chikupezeka monga mbali ya mankhwala monga "Nurofen", "Reumafen" "Brufen", "Bolinet".

malamulo NSAID

NSAIDs akhoza kugwirizana ndi angapo zotsatira zoyipazi, choncho tikulimbikitsidwa pamene kutumikiridwa kusunga Malamulo awa:

1. Werengani malangizo ndi kutsatira malangizo kuti lili - zifunika!

2. Pamene kutumikiridwa makapisozi kapena miyala ndi anawo kapu ya madzi - ichi adzateteza mimba yanu. lamulo limeneli ayenera kutsata ngakhale inu kumwa mankhwala amakono kwambiri (amene ankaona otetezeka) chifukwa kusamala owonjezera konse zidzapweteke;

3. Kodi si pogona pambuyo kumwa za theka la ora. chakuti mphamvu yokoka azipereka kwa ndime bwino kapisozi pansi kum'mero;

4. mowa ayenera adzasiyidwa, monga ogwirizana pamodzi ndi NSAIDs ndi mowa - kusokonezeka zoopsa zomwe zingachititse matenda osiyanasiyana m'mimba.

5. Tsiku lina, musamatenge awiri osiyana sanali steroidal mankhwala - izo sadzachulukana ndi zabwino, koma mwachidule mavuto.

6. Ngati mankhwala si kuthandiza, dokotala anu, mwina muli mlingo chochepa akaweruzidwa.

Zotsatira zoyipa za mankhwalawa ndipo sanali steroidal gastropathy

Tsopano inu mudzapeza zimene NSAID gastropathy. Mwatsoka, NSAIDs zonse kuonetsa zotsatira ndithu mbali. Iwo zotsatira makamaka zoipa thirakiti m'mimba. Odwala imasokoneza mawonetseredwe monga ngati

• Nseru (nthawizina amphamvu kwambiri).
• Kutentha.
• Kusanza.
• Dyspepsia.
• Magazi m'mimba.
• M'mimba.
• Mmatumbo chilonda ndi m'mimba.

Onse vuto pamwamba ndi NSAID gastropathy. Choncho, madokotala pafupipafupi mankhwala odwala awo kuyesa otsika zotheka mlingo wa sanali steroidal mankhwala tingachipeze powerenga odana ndi yotupa. Kuchepetsa mavuto pa m'mimba ndipo matumbo, izo tikulimbikitsidwa kuti konse kutenga mankhwala pa chopanda kanthu m'mimba, ndipo amachita izi chakudya katundu.

Koma mavuto ndi ziwalo m'mimba - ziri zonse zobwera mbali kuti angathe kubala ena NSAIDs osati. mankhwala ena akhoza zoipa bwanji mtima ndi impso. Nthawi zina kuwatengera akhozanso kukopeka ndi kupweteka chizungulire. Vuto lina lalikulu - iwo ndi mavuto aakulu pa kwapakati pa-articular chichereŵechereŵe (kumene okha ntchito nthawi yaitali). Mwamwayi, malonda zilipo mbadwo watsopano wa NSAIDs, amene kwakukulukulu osapatsidwa zovuta izi.

Nonsteroidal odana ndi yotupa mankhwala a mbadwo watsopano

M'zaka ziwiri zapitazi, makampani angapo mankhwala kwambiri kukhazikitsa NSAIDs ano watsopano, amene pamodzi ndi tichepetse a ululu ndi kutupa, kodi ndi mavuto ngati nkotheka. khama mankhwala anali korona bwino - gulu lonse la mbadwo watsopano wa mankhwala akhala akupangidwa otchedwa kusankha.

Tangoganizani - mankhwala moyang'aniridwa ndi achipatala akhoza aledzera maphunziro yaitali kwambiri. Ndipo nthawi ya angathe kuyeza osati kwa masabata ndi miyezi ndi zaka. Mankhwala gulu mulibe mavuto aakulu pa chichereŵechereŵe articular, mavuto ali kuli ndi kupereka pafupifupi musati chifukwa matendawo.

mbadwo watsopano wa NSAIDs - ndi mankhwala monga:

• "Movalis".
• "Nise" (Aka - "nimulid").
• "Arcoxia."
• "Celebrex".

Ndi ubwino ife kufotokoza chitsanzo cha "Movalis". Lilipo monga piritsi ochiritsira (7.5 mg ndi 15) ndi suppositories wa 15 mg, ndi ampules galasi kwa makonzedwe mu mnofu (15 mg). Mozama mankhwala ndi yofewa kwambiri, koma nthawi yomweyo kothandiza kwambiri: tsiku lonse yokwanira imodzi yokha piritsi. Pamene odwala anasonyeza chithandizo yaitali chifukwa chaukali nyamakazi a m'chiuno kapena bondo mafupa, "Movalis" imangokhala irreplaceable.

zosiyanasiyana zimene NSAIDs zilipo

Ambiri a nonsteroidal odana ndi yotupa mankhwala zikhoza kugulidwa ndi ntchito osati mawonekedwe a miyala ndi makapisozi kwa makonzedwe m'kamwa, komanso mafuta, angakhale angelo, makandulo ndi njira jekeseni. Ndithu, zabwino kwambiri, chifukwa zosiyanasiyana izi limachititsa zina kupewa kuwonongeka pa mankhwala ndi ulimi munthawi yomweyo zambiri mofulumira zotsatira achire.

Choncho, mbadwo watsopano wa NSAIDs mu nyamakazi ntchito ngati jekeseni ndi, mphamvu zochepa pa kapepala gastro-m'mimba. Koma pali mbali pepala kuti ndalama iyi: pamene kutumikiridwa intramuscularly, pafupifupi mankhwala si steroidal zingabweretse mavuto - necrosis minofu minofu. N'chifukwa chake NSAIDs jekeseni sanachitepo kwa nthawi yaitali.

Nthawi zambiri, jakisoni amaikidwa ndi exacerbation la matenda yotupa ndi osachiritsika zimfundo ndi msana, limodzi ndi ululu mumamva. Pambuyo alili bwino, izo zimakhala zotheka kuloza ku miyala ndi njira wakunja, mu mawonekedwe a mafuta.

madokotala nthawi zambiri pamakhala zosiyanasiyana mlingo zochita ndi pamene mukhoza kubweretsa phindu lalikulu la wodwalayo. Poti momveka bwino: ngati simukufuna kuvulaza okha kudziletsa chithandizo cha matenda wamba monga ululu otsika kapena nyamakazi, kupempha thandizo bungwe lina la zamankhwala, kuti kumene mudzatha kuthandiza.

Ndingatani ntchito NSAIDs pa mimba

Madokotala mwamphamvu amalangiza kutenga NSAIDs kwa amayi apakati (makamaka chiletso kwa trimester chachitatu), ndi mums amene kuyamwitsa. Akukhulupirira kuti gulu la mankhwala akhoza kusokoneza mwana wosabadwayo gestation ndi kumuchititsa malformations zosiyanasiyana.

Malinga ndi zimene mabuku ena amanena, ndi mankhwala wowona, anthu ambiri amaona ngati "Aspirin", akhoza azitaya padera mimba msanga. Koma nthawi zina madokotala chifukwa zikuonetsa analamula kuti akazi yogwira mankhwala (okha mu mtengo ndi Mlingo kochepa). Nthaŵi iliyonse makamaka, chigamulo ayenera kupangidwa ndi dokotala wodziwa bwino.

Mimba, koma amai amakhala ndi vuto kumbuyo ndipo pali kufunika vutoli ntchito mankhwala nonsteroidal antiinflammatory monga kothandiza kwambiri ndi kusala. Pankhaniyi, analola ntchito "Voltaren gel osakaniza." Koma - kachiwiri - osadalira pa ntchito n'chotheka mu trimester loyamba ndi lachiwiri, mimba ina kugwiritsa ntchito mankhwala amphamvu amaloledwa yekha moyang'aniridwa ndi dokotala.

Pomaliza

Tinakuuzanitu zimene ankadziwa zokhudza NSAIDs okha. Chinawathandiza kumvetsa n'chakuti achidule, gulu la mankhwala mankhwala, malamulo kwa phwando awo, nkhani mavuto - zingakhale zothandiza pa moyo wawo. Koma ife tikufuna kuona kufunika kwa mankhwala adanyamuka Owerenga zochepa ngati n'kotheka. Choncho, pa omaliza tikufuna inu zabwino athanzi!