"Passazhiks": malangizo ntchito. "Passazhiks": zikuonetsa ntchito, Akhristu enieni

Kusanza reflex otchedwa kuphulika pakamwa (zina mwa mphuno), nkhani za m'mimba kapena duodenum 12. chodabwitsa Ichi ndi chifukwa ndi minofu kuchepetsa atolankhani.

Pa kusanza linanena bungwe gawo la mmimba anatseka ndipo thupi lake ndi omasuka kwathunthu. Mu pakhomo izi anatsegula, ndi kukulitsa kum'mero ndi m'kamwa zibowo zam'mano.

Onse anafotokoza kuchita reflex umalamulidwa ndi pakati kusanza, limene lili mu medulla oblongata. Izi boma la munthu angathe kuona matenda, poizoni, kudzikundikira poizoni mu magazi, ndi mkwiyo peritoneal, zilonda, gastritis, akazi apakati ndi ena.

Episodic kusanza si limodzi ndi magazi, ndipo alibe zingasokoneze moyo wodwalayo. Koma ngati ndondomeko izi kawirikawiri kwambiri, kungachititse kuti mavuto aakulu. Zikuphatikizapo madzi m'thupi ndipo electrolyte vutoli zimene zingachititse kuti imfa. N'chifukwa chake n'kofunika kuwona dotolo pamene nthawi kusanza. Kunatanthauzanso kutenga mankhwala wapadera, amene amathandiza kuti akathetse reflex.

Wotchuka kwambiri antiemetics monga mankhwala monga "Passazhiks". Zikuonetsa ntchito mankhwala ndi malangizo Adzaperekedwa pansipa.

mawonekedwe kumasulidwa, zikuchokera ndi wazolongedza

Kodi maonekedwe alipo mankhwala "Passazhiks"? Ogula ndemanga kudziŵitsa kuti mankhwala chogulitsidwa mawonekedwe a mapiritsi chewable. Iwo ankanyamula mu matuza ndi mukatoni, motero.

The yogwira pophika ankaona mankhwala amachita domperidone. Monga mankhwala othandiza ntchito ndi aspartame, xylitol, lactitol, magnesium stearate ndi menthol.

makhalidwe pharmacological

Malangizo ntchito ( "Passazhiks" ayenera kugwiritsidwa ntchito ndi mankhwala) akusimba kuti wothandizila ndi imatengedwa odana ndi emetic mankhwala. Ndi antagonist ya maselo chapakati dopamine.

Yogwira medicament angathe kuwonjezera nthawi ya contractions peristaltic mu antrum za m'mimba ndi duodenum 12. Komanso Iyamba Ndikudzikhuthula kwa nkhani za kapepala m'mimba (pa deceleration za ndondomeko), kumatha kunyansidwa ndi kusanza, kumaonjezera kamvekedwe wa sphincter esophageal (m'munsi gawo).

Tiyenera kuona kuti domperidone m'malo bwino likulowerera magazi ubongo chotchinga. Ndicho chifukwa chake ntchito mankhwala kawirikawiri limodzi ndi zochita extrapyramidal.

Iwo ayenera kukumbukira kuti domperidone angathe kuwalimbikitsa prolactin kumasulidwa ku pituitary lapansi.

Action (antiemetic) za mankhwala chifukwa zochita za mitundu gastrokinetic ndi dopamine chidani mu zone chemoreceptor choyambitsa. Tiyeneranso kuti thunthu alibe zotsatira likuwonongekera katulutsidwe muzituluka.

katundu kayendedwe

Kodi chibadidwe kayendedwe magawo medicament "Passazhiks"? Malangizo ntchito limasonyeza kuti pambuyo kutenga chewable phale, yogwira pophika ndi ndithu mofulumira odzipereka mu m'magazi.

Domperidone ali otsika bioavailability (pafupifupi 15%). ndende yake pazipita zimawonedwa pambuyo Mphindi 65.

Yafupika acidity chapamimba kungachepetse mankhwala mayamwidwe.

Akatswiri amanena domperidone ndi inafalitsidwa mu zimakhala zosiyanasiyana. Monga ubongo, ndende ya mankhwala ali ang'ono. Kulankhulana ndi mapuloteni plasma ndi za 92-93%.

Komanso dziwani kuti mankhwala "Passazhiks" (mapiritsi) ndi zimapukusidwa mu chiwindi ndi m'matumbo khoma. Linanena bungwe izo kudzera intestine (za 66%) ndi impso (pafupifupi 33%).

The theka moyo wa mankhwala ndi maola 7-8. Mu kulephera aakulu aimpso anapatsidwa imeneyi ndi lengthened.

umboni

Ankaona medicament analamula kuti kunyansidwa ndi kusanza ya chiyambi osiyanasiyana, kuphatikizapo matenda organic ndi zinchito mankhwala cheza ndi matenda. Komanso, chida ichi chikhonza chija mu toxemia, kutenga morphine, kuyan'anila zakudya, kugwiritsa ntchito "Levodopa", "Apomorphine" ndi "Bromocriptine".

Kodi Nthawi zina mankhwala angagwiritsidwe ntchito "Passazhiks"? Malangizo ntchito akusonyeza kuti mankhwalawa kawirikawiri zotchulidwa pa atony wa kapepalako m'mimba (kuphatikizapo postoperative), hiccups, radiopaque ndi endoscopic m'mimba maphunziro thirakiti. Komanso ankaona mankhwala chofunika kuti imathandizira peristalsis njira yodziwira, matenda dyspeptic akuwuka chifukwa cha mochedwa chapamimba Ndikudzikhuthula, esophagitis, ndi gastroesophageal Reflux.

Miyala "Passazhiks" zizindikiro zomwe zafotokozedwa pamwamba bwino kuonekera mu kumverera kwa chidzalo m'mimba, flatulence, bloating kutengeka, gastralgia, kutentha pa chifuwa ndi belching.

contraindications

Pamene muyenera kugwiritsa ntchito mapiritsi "Passazhiks"? Malangizo ntchito, ndemanga kuti akanene contraindications kutsatira mankhwala pansi kulingalira:

• hypersensitivity;
• Ana osaposa zaka 5, komanso ana masekeli mpaka makilogalamu 20;
• prolactinoma;
• fenilketonuriyaiya.

Iwo ayenera kukumbukira kuti chida si anasonyeza ngati galimoto kukondoweza m'mimba n'koopsa (kwa magazi m'mimba, perforation, kapena kutsekeka mawotchi).

Chenjerani ndi mankhwala angagwiritsidwe ntchito odwala insufficiency aimpso kapena kwa chiwindi pa mimba ndi mkaka wa m'mawere.

Miyala "Passazhiks": malangizo ntchito

mapiritsi Chewable "Passazhiks" analimbikitsa pitiliza ¼ ola asanadye.

Akuluakulu aakulu dyspepsia akapitawo 10 mg mlingo (piritsi 1) katatu patsiku. Ngati ndi kotheka, mankhwala akhoza kumwedwa nthawi yogona.

Ana okulirapo kuposa zaka 5, chida ichi kupereka 2.5 mg wa pa makilogalamu 10 thupi katatu pa tsiku ndipo ngati n'koyenera, asanagone.

Mu subacute kapena limati pachimake (nseru, kusanza) kutumikiridwa odwala wamkulu wa 20 mg wa kanayi pa tsiku, ndi pamaso yogona. Ana okulirapo kuposa zaka 5 tikulimbikitsidwa kuti atenge 5 mg wa mankhwala pa makilogalamu 10 thupi kanayi pa tsiku ndi nthawi yogona.

Mu kulephera aimpso amafuna mlingo kusintha multiplicity kulandira nthawi zoposa 1-2 pa tsiku.

Mlingo pazipita mankhwala patsiku kwa akulu ndi 80 mg (ie mapiritsi 8). Pankhani ana, sayenera kuposa 10 mg pa 10 makilogalamu kulemera kwa mwanayo.

zotsatira zoyipazi

ngati zochita chowawa mapiritsi chewable "Passazhiks" chifukwa? Akatswiri Mlendo kuti chida ichi zingachititse mavuto mu mawonekedwe a:

• chosakhalitsa matumbo omangana;
• extrapyramidal zotsatira;
• kuonjezera prolactin ndende mu madzi ndi;
• galactorrhea, gynecomastia ndi dysmenorrhea;
• totupa, ndi urticaria.

Zizindikiro cha mankhwala osokoneza bongo

ndi zizindikiro cha mankhwala osokoneza bongo zingachititse mankhwala "Passazhiks" n'chiyani? limati Manual kuti zinthu zoterozo monga kugona, disorientation ndi zochita extrapyramidal.

Ndi bwino kutenga adamulowetsa makala ndi dokotala mankhwala zinthu zimenezi.

Mogwirizana ndi mankhwala ena

Munthawi yomweyo mankhwala mankhwala "Passazhiks" ndi anticholinergics akhoza n'chongoletsa zotsatira za woyamba.

Kulumikizana ndi Mankhwalawa ayenera kumwedwa kuchepetsa bioavailability ake.

Zimagwira ndi domperidone medicaments inhibiting ndi isozyme CYP3A4 (mwachitsanzo, macrolides mankhwala, azole antifungals gulu, ndi antidepressant "Nefazodone" HIV protease zoletsa), wodwala akhoza kumva kuwonjezeka ndende ya mankhwala yogwira m'magazi.

Ankaona mankhwala sikumangotikhudza ndende ya digoxin mu madzi ndi paracetamol. Si lilibe kuti zingakhudze mayamwidwe mankhwala (imodzi ntchito pakamwa) ndi mochedwa amasulidwe yogwira pophika kapena enteric-lokutidwa.

Kuyamwitsa ndi mimba

Mankhwala "Passazhiks" amaletsedwa kujambula pa mimba.

Pa fairer kugonana domperidone ndende mu mkaka ndi kanayi poyerekeza ndi madzi a m'magazi. Sizikudziwika ngati uyu ali kungasokoneze ana. Choncho, ngati n'koyenera, ntchito mankhwala pa mkaka wa m'mawere yoyamwitsa ayenera anasiya.

Miyala "Passazhiks": Anzawo ndi mtengo

Mtengo wa ndalama ndi za 220-360 rubles. Ngati n'koyenera, mankhwala antiemetic akhoza m'malo ndi wina wa mankhwala monga "Motilium", "Domstal", "Kinedril", "Avioplant", "Doprokin-C", "Diskineton", "Emeset", "Motinol" ndi zina. d.

Iwo ayenera kukumbukira kuti onse ndalama izi mwina ndi makhalidwe awo. Choncho, ntchito m'malo "Passazhiksa" akhale yekha atakambirana ndi dokotala.

Reviews kukonzekera

Ambiri odwala kuchizidwa ndi mankhwala mu funso, kulankhula za dzuwa ake okwezeka. Malinga owerenga, izi zikutanthauza wokongola msanga kuthetsa maganizo nseru ndiponso kupewa kusanza.

Iwo ayenera kukumbukira kuti mankhwala akhoza kumwedwa ndi zizindikiro zina. Mwachitsanzo, amagwiritsidwa ntchito kawirikawiri pa kulemera m'mimba kapena distention m'mimba. Pankhaniyi, miyala chewable amalangiza kumwa panthawi imodzi katatu pa tsiku kwa masiku asanu.

The zovuta yaikulu yokonza "Passazhiks" amatanthauza mavuto akuwuka ndi phwando ake, komanso pamaso pa contraindications osiyana.