The timadzi testosterone ndi ntchito yake mu thupi

Anthu, pali zofunikira ziwiri limagwirira cha lamulo ziwalo ndi machitidwe: wamanjenje ndi humoral. The woyamba ikuchitika, chifukwa cha innervation zambiri za ziwalo, zopangitsa, mitsempha ya magazi ndi minofu ndi Mitsemphayi.

Limagwirira chachiwiri ndi chifukwa lakutali timadzi kanthu zimene iwo amatuluka mu zopangitsa za endocrine, kenako anasamutsa m'magazi a mu minofu kapena chandamale limba. Choncho, timadzi testosterone, mphunzitsi androgen, amapangidwa zochepa ndi kotekisi adrenal, ndi pa zosayembekezereka wa msinkhu anyamata ayamba kutulutsa mwachangu testes, ndiye iye excretory ducts la England limasuka mu magazi ndiponso ali ndi mphamvu pa dongosolo minofu ndi mafupa, ndi pa kagayidwe mu chiwindi. Malinga ndi mfundo za maganizo testosterone amatha zonse ulimi wa mahomoni ena (monga mkazi thupi mwamuna).

testosterone ntchito

Testosterone milingo anthu, ndithudi, apamwamba kuposa mlingo wake mu akazi, chifukwa mu thupi mwamuna izo amagwira ntchito zambiri: mu msinkhu anyamata muulamuliro wake, ndi mapangidwe otchedwa sekondale makhalidwe kugonana, ndiko kuti, "kunyema" mawu ukugwirizana lamba phewa poyerekeza ndi mafupa a chiuno ndi, kuwonjezera minofu misa ndi fupa compaction kusasitsa wa gametes mu gonads lapansi.

Mu amuna wamkulu, iye kumathandiza kuti ntchito yokonza ntchito kugonana, ndiko kuti, chilakolako cha kugonana, potency ndi amapanga psychophysiological kugonana. The timadzi testosterone ndi opangidwa mu akazi: mu kotekisi adrenal, mazira ndi kutembenuka timafunika. Iye ali ndi zotsatira ochepetsera pa kusasitsa wa follicles yamchiberekero ndi nthawi yopanga estradiol ndi estrone mwa olamulira hypothalamic-pituitary-adrenal. Pamene hypersecretion akazi ake kapena makonzedwe yokumba mankhwala okhala ndi timadzi (ambiri anabolic mankhwala), masculinization mu akazi zingachitike kumaonekera mu kuzama kwa mawu, kuchuluka thupi tsitsi, chitukuko minofu ndi makhalidwe aukali.

Lamulo katulutsidwe wa testosterone

Pali njira zingapo zimene zimakhudza mlingo wa testosterone. Norma amuna ndi 11-33 nmol / lita, ndi akazi - yekha 0,24-2,7. Mu nkhani iyi, timadzi testosterone m'magazi ali tuzigawo twa awiri; Mfulu nam'manga kunyamula mapuloteni albumin ndi globulin yeniyeni angathe kumanga kugonana mahomoni (SHBG). Komabe, ntchito kwachilengedwenso kuwawonetsera yekha kwaulere (2% ya okwana) ndi testosterone womangidwa kwa albumin. Patatha zaka 30-35 amuna ndi timadzi testosterone monga bioavailability ake, komanso kachigawo okwana amakonda ndichepe pa mlingo avareji% 2-3 / chaka, ndi ukalamba mlingo wa testosterone yogwira yafupika nthawi 5 (poyerekeza ndi achinyamata) ndi onse - nthawi 2.5. Malinga ndi malipoti ena, izi si kuchepa pang'onopang'ono katulutsidwe ake, koma kowonjezeka kumanga kwa SHBG, motero bioavailable kachigawo deactivated.