Mankhwala "Paracetamol" - zikuchokera, zizindikiro, contraindications

Kukonzekera "Paracetamol» amene zikuchokera ndiyo mphamvu ya mankhwala ndi kuchepetsa kutentha ndi kuchepetsa ululu ndi otchuka analgesic ndi antipyretic a gulu anilide. Fomu mankhwala kumasulidwa ndi yosiyanasiyana. Izi madzi ndi suppositories, chimapatsa ndi madontho, mapiritsi (mbalambanda, chewable ndi effervescent), komanso njira jekeseni ndi makonzedwe mkati.

Kukonzekera "Paracetamol" amene chilinganizo limapangidwa mankhwala pawiri N- (4-Hydroxyphenyl) acetamide, ndi metabolite wa phenacetin ndipo ali katundu yofanana ndi iyo. Ubwino waukulu medicament akhoza monga kawopsedwe ake otsika ndi luso kupanga ang'onoang'ono methemoglobin. makonzedwe aakulu a mlingo waukulu, mankhwala zingachititse maonekedwe a zochita zoipa, koma mankhwala "Paracetamol" lopangidwa ndi otetezeka zili m'gulu la WHO mndandanda wa analgesics yabwino kwambiri akulimbikitsidwa kugwiritsa ntchito ana. Kumbali ya maonekedwe, ndi crystalline ufa ndi loyera kapena kirimu yofiira ndi kum'chitira pinki. Paracetamol mosavuta kusungunuka mowa.

Pa zotsatira pharmacological pa midadada mankhwala thupi enzyme cyclooxygenase mphamvu prostaglandins. Mankhwala "Paracetamol" amene zikuchokera zingasokoneze pakati pa ululu ndi lamulo la kutentha amakhudza chapakati mantha dongosolo. The mankhwala ndi chosakanikirana ndi dongosolo m'mimba mwa yochepa ndi chimango zonsezo plasma kuchuluka peresenti khumi. kusintha mankhwala thunthu yogwira opangidwa mu chiwindi. Izi ndipamene paracetamol glucuronide ndi sulphate. Excreted zinthu mankhwala excreted kudzera impso. Pamene kulandira mankhwala lactating akazi mu mkaka wa m'mawere peresenti pasanathe imodzi mlingo wa mankhwala.

Anamuika mankhwala "Paracetamol" amene zikuchokera limachititsa lichotse lotopetsa ndi ululu, zochizira matenda, chikhalidwe matenda wodziwika ndi. Iwo akhoza kukhala arthralgia ndi neuralgia, myalgia, ndi migraine algodismenorei ndi matenda a mano ndi mutu. Mankhwala alibe mphamvu pa kupitirira kwa matenda ndi cholinga cha zotsatira symptomatic ndi mpumulo zosakhalitsa alili.

Zotsatira zake zoyipa "Paracetamol" kufotokoza mankhwala angapezeke malangizo zingadzetse kuphwanya mapangidwe ziwalo kugonana mwana wosabadwayo pamene akulandira mankhwala ndi mkazi wapakati. Chifukwa cha ntchito mankhwala akhoza kukhala pyuria aseptic, aimpso colic, kuchepa magazi, anemiyainterstitsialny glomeruonefrit ndi thupi lawo siligwirizana pa khungu.

Mankhwala "Paracetamol" ndi osankhidwa pansi zinthu zotsatirazi:

- munthu kudziwa kapangidwe kake,

- erosions ndi njira chilonda mu dongosolo m'mimba;

- pamodzi bronchial mphumu polyposis mphuno ndi sinuses paranasal wa muyambirenso mu siteji;

- tsankho asidi acetylsalicylic;

- matenda mwapang'onopang'ono impso khalidwe;

- matenda yotupa pa mundawo m'mimba;

- Amalalikira chiwindi matenda;

- magazi kapepala kakuti m'mimba;

- konzanso pambuyo inatsekeratu mtsempha wamagazi kulambalala opaleshoni;

- hyperkalemia.

Anakana kutenga mankhwala mu trimester wachitatu wa mimba, monga sapereka ongobadwa kumene mwezi wa moyo.

Ndi kwambiri ntchito mosamala ya nkhaniyi mankhwala kwa matenda otsatirawa:

- chiwindi tizilombo;

- uchidakwa;

- impso, chiwindi ndi matenda a mtima;

- shuga;

- matenda somatic chaukali;

- zotumphukira matenda wolumikizira;

- chikonga bongo;

- mtima ischemia.