Peroxisome ntchito. syndrome Zellweger

Today tikukupemphani kuganizira peroxisome ntchito. Kodi phindu ali mu khola? ifenso kulabadira zimene matenda kuonedwa ndi thandizo la organelle izi.

Kale m'mawu oyamba, zikuonekeratu kuti peroxisomes - izo organelles. Selo nayenso ali m'gulu la mlengi yodabwitsa kwambiri wa zonse otizungulira. Ngakhale munthu imakhala ndi maselo, limene pali ochuluka zedi. Ndi selo ndi mbali ngakhale ang'onoang'ono, koma iwo amalola kukhala ndi ufulu, kutanthauza kuti kugwirizana kulenga nyumba zovuta Sikuti. Chitsanzo cha zimenezi ndi losavuta zokhala ndi selo imodzi zolengedwa, amene inu mwinamwake munamva mu maphunziro zamoyo kusukulu.

Pamaso tikungotchula ndi kufotokozera peroxisome ntchito, tiyenera kumvetsa chimene icho chiri ndi momwe ntchito.

peroxisomes

organelles enawa vacuoles chaching'onong'ono, kukula ndi pansipa 1.5 micron. Peroxisome atazunguliridwa ndi Kakhungu woonda, ndipo alekanitsa microgranules mkati, kwa chilengedwe mkati mwa selo lonse. Kodi tingapeze mwa organelle chiyani? Pali pachimake, limatchedwanso ndi nucleoid. Nkofunika kumvetsa mfundo yakuti gawo ili la peroxisomes alibe poyerekezera ndi kapangidwe nyukiliya kapena mabakiteriya nucleoid. Sizikusokonezani mfundo izi. ndipo nthawi zambiri kotero kuti nyumba wapezeka kutengera timibulu zone nucleoid. Iwo anapanga kuchokera fibrils ndi machubu. Phata la organelle izi wosiyana peroxisomes ndi, uratoksidoza zili mkati mwake. Ichi ndi chimodzi mwa michere ya. Tsopano ife akamufunsirire kuganizira peroxisome ntchito mu selo. Koma zisanachitike, tione kukonza.

kapangidwe

Tsopano ife tinena zimene peroxisomes, kapangidwe ndi ntchito (onani gome) adzamva kuonedwa ndi ife. Kuyamba ndi ife kupereka chithandizo zithunzi mu mawonekedwe a tebulo. Kenako, kulemba mwatsatanetsatane dongosolo ndi ntchito ya peroxisomes. Tebulo akhoza analengedwa ndi ife, koma zitakwaniranso dziwani kuti peroxisome masanjidwewo ndi tichipeza nyukiliotayidi a.

Masanjidwewo 15 lili peroxisome michere. Tiyeni tione zina. Polongosola zofunika kwambiri a iwo:

• peroxidase;
• catalase;
• oksidoza;
• uratroksidaza.

Ndipo kodi ntchito ndiye amachita nyukiliotayidi? udindo wake ndi condense anthu michere chomwecho. Tiyeni tione kuti ndondomeko kupanga peraksisom. Iwo idzaphuka ku EPS, kotero ife tikhoza kunena kuti dera yopanga organelle izi - ndi CSE. Michere amatuluka mu:

• EPS;
• hyaloplasm.

Apa m'pofunika kuti anthu amvetse mfundo yakuti Kakhungu, ngakhale wochepa thupi, koma mkatikati ngakhale ayoni ndi otsika magawo maselo kulemera. Tsopano tingaganizire ntchito ya peroxisomes. Paja organelle zimenezi n'kofunika kwambiri chifukwa selo.

ntchito

ntchito Peroxisome ali motere:

• makutidwe ndi okosijeni zinthu organic;
• mafuta asidi makutidwe ndi okosijeni;
• biosynthesis plasmalogens;
• isoprenoid biosynthesis nyama;
• biosynthesis wa mafuta m'thupi;
• NDR2 mapuloteni kutanthauzira;
• lamulo zokhudza zonse kutupa;
• thandizo mu ndondomeko ya kupuma mu chomera maselo, ndi zina zotero.

mndandanda ndi yaitali kwambiri, chifukwa ena ntchito si bwino. Tsopano timapereka kwambiri pang'ono kulankhula za kaphatikizidwe mapuloteni. Nkofunika kudziwa kuti organelles izi zili mbali monga:

• DNA;
• ribosome.

Choncho, kaphatikizidwe mapuloteni amapezeka phata la. Kenako chiyani chilengedwe mkati mwa peroxisomes. Kodi maziko a inatha bwanji? Kugwira C-osachiritsika chizindikiro. The ndondomeko ya kutsata ichi ndi yochepa kwambiri, wopangidwa mwa zatsalira 3 kwa amino acid.

The phindu kuona yachipatala

Takambirana mu chigawo yapita, amene ntchito imagwiridwa ndi peroxisomes. Tsopano pang'ono za matenda deta kopita organelle. Tsopano ife kulankhula pang'ono za matenda otchedwa - Zellweger syndrome. Ichi ndithu ndi matenda aakulu, ndi chifukwa cha kuphwanya mapuloteni inatha. Choncho, peroxisomes kanthu, selo ndi chamoyo wonse wapezeka deta pachimake kulephera organelles. Anthu amene amadwala matenda amenewa amavutika ndi ntchito ya matupi ena ofunika pano ndi monga:

• ubongo;
• chiwindi;
• impso.

Ana amene amabadwa ndi matenda ili silingathe kukhala ndi moyo nthawi yaitali ndipo kuti achoke mdziko wathu yochepa kwambiri kukhala. Matendawa amagwirizana ndi kusintha kwa organelle lapansi. N'zothekanso ndi zochepa oopsa mitundu ya matenda.