Prolactinoma pituitary England: zimayambitsa, zizindikiro, matenda ndi mankhwala. The pituitary England ndi udindo wotani?

Munthu amaona zovuta azachipatala zimayamba disassemble mu zigawo zake pofuna kumvetsa matenda awo. Choncho, funso lake loyamba nokha ndi: "Kodi likukwaniritsa pituitary?". Atafufuza mozama mfundo iye amaona kuti izi endocrine England, amene nthawi machitidwe a zopangitsa ena onse m'thupi. mudziwe zambiri idzagwira wodwalayo mndandanda umatulutsa timadzi awo ndi ziwalo chandamale. Ndipo pambuyo kuti anasankha atapeza zimene zikutanthauza kuti mawu akuti "prolactinoma pituitary." Izi ndi chotupa limene limatulutsa timadzi kwambiri, thupi lingathe iwo. Owonjezera prolactin ndipo amachititsa zizindikiro khalidwe matenda. Koma zinthu oyamba.

Kodi pituitary England?

The pituitary England ndi udindo wotani? Pituitary England - ndi gawo la midbrain ndi, inali pamwamba woyambira mu mapangidwe fupa amatchedwa "Turkey chishalo." iyo ili amatulutsa timadzi malamulo kukula anthu, mlingo wa kagayidwe ndi kubalana a mbadwa. Pituitary England - wochititsa dongosolo endocrine. Zimavuta ndi ubongo imene imalamulira kutentha, pamodzi iwo kulamulira thupi, kupereka ntchito zake zofunika kwambiri.

Mu pituitary England ndi zigawo zitatu kapena magawo:

1. Zapambuyo Lobe umabala mahomoni lotentha. Iwo wotchedwa chifukwa iwo bwanji ziwalo zina ndi mankhwala anatsekula kuti zimakhala zawo. Njirazi ndi monga:
   - chithokomiro zolimbikitsa timadzi (wokhudzana ndi chithokomiro England);
   - adrenocorticotropic timadzi (kumapangitsa munthu zopangitsa adrenal);
   - follicle-zolimbikitsa timadzi (amazilamulira ntchito kugonana, kupangira kusasitsa wa oocytes);
   - luteinizing timadzi (kumapangitsa ovulation);
   - Growth timadzi udindo wotere pa kukula;
   - luteotrophic timadzi kapena prolactin (nthawi maonekedwe a colostrum ndi mkaka wa amayi apakati ndi udindo Mwachibadwa ndi akuchikazi). Prolactinoma pituitary kusiyana mu Lobe zapambuyo, ndi "makhalidwe" ntchito luteotrophic timadzi.
2. The zapambuyo Lobe wa tochoka vasopressin (udindo kukhalabe magazi ndi minofu madzi yachibadwa kuthamanga), ndipo oxytocin, lomwe ndi lofunikira pa mimba ndi woyamwitsa mwana. Chili pa minofu yosalala, kuchepetsa.
3. Wapakati chiwerengero cha mahomoni apanga kuti yotithandiza maselo a khungu - melanocytes.

Nchito ngati n'zosavuta ndikuganiza, pituitary zosiyanasiyana. Iwo umakulamulira selo magawano ndi mapuloteni synthesizing kumanga minofu latsopano. Komanso, nthawi kusasitsa mazira ndi umuna, komanso ayankhe thupi mahomoni kugonana. Ndi zina ndi chitetezo cha m'thupi ndi zolimbikitsa kapena inhibiting ntchito ya chithokomiro lapansi. Iwo umakulamulira milingo magazi mu zotengera magazi, kuchuluka kwa misa mafuta ndi khalidwe la kugona. The pituitary England palibe maola 24 pa tsiku, masiku 7 pa mlungu, miyoyo yathu.

Prolactin - ndichiyani?

kumvetsa pang'ono za thunthu ndi Maphunziro Akakhalidwe Kazolengedwa a dongosolo endocrine, mukhoza chitani kuwunika mwatsatanetsatane. Kumene, mofulumira, popanda maphunziro apadera izo sizidzakhala zophweka, koma mukhoza kuchititsa. Mu matenda, kuwonjezera mawu akuti "pituitary", kunali prolactin. Ndi chiyani icho?

Prolactin - ndi imodzi mahomoni ndi tochoka ndi maselo acidophilic wa pituitary zapambuyo. Akuphatikizapo mankhwala limatanthauza nyumba mapuloteni. Asayansi olekanitsidwa banja lonse la zinthu ndi ofanana makhalidwe maselo. Njirazi ndi monga:

- prolactin;
- proliferin (amazilamulira kugawikana kwa maselo connective minofu);
- kukula timadzi;
- placental lactogen (tochoka pa mimba).

Pakalipano katundu prolactin mwachindunji kapena ayi udindo ntchito kugonana ndi kubereka. Chandamale limba ali, monga dzina lake likunenera, ndi zopangitsa mammary. The timadzi kumapangitsa yopanga colostrum ndi kutembenuka ake mu mkaka. Pa msinkhu ndi pa mimba ndi udindo kukula ndi chitukuko cha zopangitsa za mammary, chiwerengero cha lobules ndi ducts. Chidwi mfundo: The zolandilira kwa prolactin amapezeka pafupifupi ziwalo zonse ndipo zimakhala za thupi la munthu, koma chimene zake ali pa iwo akadali osadziwika.

prolactinoma pituitary ukapezeka chifukwa masinthidwe maselo a pituitary zapambuyo. Iwo amakwiya yopanga kwambiri ya prolactin ndipo umatithandiza katundu wake, ndipo izi zimakhudza umoyo ndi maonekedwe a wodwalayo. Mwamwayi, matenda ndi mankhwala a matenda adziwika kale ndipo bwinobwino anayesedwa, kotero matenda - osati chiweruzo.

prolaktinoma

pituitary prolactinoma amatanthauza pafupipafupi chosaopsa matenda a pituitary zapambuyo (powerengera, 30 peresenti ya zotupa zonse matenda). Common mu akazi a msinkhu wobereka. Chiŵerengero pakati olimba ndi kugonana chilungamo - 1 mpaka 6.

Kutalika kwa izo, monga ulamuliro, musalumphe millimeters awiri kapena atatu, koma anthu akhoza kukumana ndi maphunziro aakulu - kuposa centimeter awiri. zotupa Awa hormonally yogwira, monga iwo amapanga prolactin. Mwachibadwa iwo apanga mu amuna ndi akazi. Prolactin angachite akuluakulu palokha kapena molumikizana ndi luteinizing ndi follicle-zolimbikitsa timadzi. Makamaka zochita zawo chimaoneka pa mimba ndi mkaka wa m'mawere. Koma kupyola pamenepo, iwo zonse za msambo ndipo ovulation.

yambiri timadzi ali ndi azisiyana. Mkazi amakhala mwachitsanzo osabereka sangathe pakati ndipo adzabala mwana. Anthu amene ali titers mkulu wa prolactin ndi mavuto ndi potency ndi erection chizindikiro zotengera malingaliridwe ndi cholinga bere kukulitsa.

zifukwa

Asayansi osati asanaganize motsimikiza chifukwa chake munthu ali ndi neoplasm, koma anaona zina wamba wamba odwala onse ndi matenda amenewa.

Funso loyamba, ndithudi, ndi obadwa nawo majini matenda a dongosolo endocrine. Childs, izi neoplasia angapo (ie, chotupacho ali pafupifupi zopangitsa za katulutsidwe mkati). Pali kupanga owonjezera prolactin, osati kokha, komanso mahomoni a chithokomiro ndi zopangitsa parathyroid, kapamba, zopangitsa adrenal, pituitary England ndi kukhalapo kwa zilonda m'mimba.

Amadziwika kuti achibale mwayi kuti kudwala izi kuposa pafupifupi kwa anthu. chibadwa Modern sakupereka ndi akuyembekezera amatha kusintha makhalidwe a maselo zapambuyo pituitary, koma mpaka kupambana m'munda umenewu palibe.

Gawo

Pituitary adenoma (prolactinoma) siyana ndi malo mwa sella. Zotupa secrete magulu awiri:

1. Intrasellyarnye prolactinomas kuti musalumphe centimeter wina kukula ndi asapitirire malire a pituitary fossa fupa.
2. Ekstrasellyarnye prolactinoma ndi lalikulu ndi wodzaza kupitirira sella lapansi.

Kukula chotupa amadalira popereka zizindikiro. Izi akugwira ntchito osati kanthu mndandanda wa timadzi lapansi. The kutupa volumetric akakufinyani nyumba zina ubongo, kuchititsa ambiri ndi focal ubongo symptomatology. Zimenezi zingakhale khungu, imfa ya fungo, imfa ya wina cranial mitsempha (trigeminal, nkhope, oculomotor). Zizindikiro Common monga mutu, maganizo maganizo, nkhawa, irritability ndi lability maganizo.

Prolactinoma pituitary: zizindikiro mu akazi

Kwa nthawi yaitali, mkazi sangakhale zindikirani kusintha modetsa nkhawa mu thupi lanu, makamaka ngati ali, ndi matenda anali ndi mavuto ndi kuzungulira kusamba. Odwala anati kuchepetsa chiwerengero cha masiku a msambo, ndi wosaperewera wa secretions kapena kusapezeka kwawo. Madona amene akufuna kukhala ndi mwana sangathe kutero, kuyambira ovulation zimachokeradi.

Zizindikiro zina ziti zimachitika akazi? prolactinoma pituitary kumapangitsa yopanga colostrum ndi mkaka, ngakhale ya anthu kugonana chilungamo amene sitili okonzeka kukhala amayi. Madzi m'malovu akhoza kumasulidwa ndi psinjika makina a nipple kapena kulepheretsa yekha (zambiri chifukwa wambirimbiri mkaka). Akazi ndi maonekedwe a zizindikiro zimenezi mu malo oyamba kuganizira khansa kapena kusintha zina, koma kuphunzira mukhoza kupeza muzu wa vuto.

Zizindikiro za pituitary prolactinoma mu akazi - si kusankha colostrum ndi mkaka, izo ndi kuwonjezeka mu fupa fragility kuti kufooka kwa mafupa. Komanso, kuperewera mu mahomoni ena, monga esitirojeni amachititsa posungira madzimadzi thupi, ndi kulemera mofulumira phindu. Maonekedwe kusintha kwambiri - polymorphic ziphuphu zakumaso totupa, kuchuluka hairiness pa milomo chapamwamba ndipo pamwamba pa makutu. Zonsezi atikhudze pa lingaliro wa madokotala ndi pituitary chotupa.

Zizindikiro za amuna

pituitary prolactinoma anthu kuwonetsera kuchepa madzi a testosterone ndi mkhutu mapangidwe nyongolosi selo. Lomwe chifukwa sterility. Koma ndi aspermia anataya ndi erection, yafupika kugonana galimoto, potency amachepetsa.

Komanso, oimira theka amphamvu anaona ponso ndi kusintha mawonekedwe a bere - gynecomastia. Monga ulamuliro, si zachilendo mu Akatswiri, lolunjika pa m'ndandanda wa minofu misa, ndi munthu amene si kulandira mankhwala, ayenera kukhala chizindikiro oopsa. Nthawi zina chifukwa cha bere kuchuluka akhoza kutayikira mkaka.

Komanso, anthu kenako manja a zopangitsa kugonana, atasowa sekondale otchulidwa kugonana, zikuoneka fragility kwambiri mafupa ndi kufooka minofu.

diagnostics

Pituitary chotupa (prolactinoma) nthawi zambiri anatsimikiza pambuyo neuroimaging Kupenda (kulingalira maginito kumveka). Osati kungoyang'ana kuwombera panolamiki, ndi amadza kufufuza pituitary kudwala ntchito kusiyana wothandizila - gadolinium, lotentha neuroendocrine minofu. Kujambula angathe kudziwa kukula ndi malo zotupa pa.

Pamene wochepa chotupa, mpaka centimeter wina, m'pofunika ntchito yopangidwa tomography, chifukwa kwambiri nkhani. CT kuoneka bwino dongosolo fupa ndi kusintha awo mu njira ya kukula kwa adenoma.

Koma kuwonjezera pa njira malangizo amene akufunika kuti definitively kutsimikizira matenda ndi kukonzekera opaleshoni, pali zasayansi njira yodziwira. Woyamba ndi kudziwa mlingo wa prolactin m'magazi. kuwunika ayenera kuchitidwa katatu pa masiku osiyanasiyana kuzungulira kusamba kulamulira zotsatira zabodza HIV kapena zonama alibe chifukwa cha nkhawa kapena kusinthasintha thupi. Zotsatira kusonyeza nanograms oposa 200 pa milliliter, pafupi kwathunthu limasonyeza kukhalapo kwa chotupa.

Ngati milingo prolactin ranged ku nanograms 40 100, zikuoneka kuti Chiwerengerochi chifukwa cha kuchepa chithokomiro ntchito, zoopsa chifuwa, kapena kukanika aimpso. Kumene, diagnoses zimenezi zilinso zolimbikitsa.

Kwambiri kuwulula mayeso thyrotropin. Pambuyo makonzedwe mtsempha theka la ola pakhala kuwonjezeka prolactin. timadzi ndende ndi osachepera kawiri cha Momwe Ziriri Pano. Pamene odwala prolaktinome kuchuluka kwa prolactin m'magazi sasintha kapena kuchuluka pang'ono. Ngati timadzi mlingo nthenda kuwonjezeka si chifukwa chotupa, ndi zinthu zina zimachitika kuti thyroliberine adzakhala pafupi mwakale.

Musaiwale kufunsa akatswiri zokhudzana ndi mafunso kusamala wodwala. Kuti kudwala akuganiza, nthaŵi zina zokwanira kufunsa mafunso abwino.

chithandizo

Chithandizo cha pituitary prolactinomas zambiri mankhwala. Njira umalimbana kuchepetsa kuchuluka kwa timadzi ndi mavuto ake kukhazikika. Kusankha mankhwala ndi mlingo kamwedwe awo m'thupi yemwenso anachita okha m'manja mwa matenda zasayansi. Pa nkhokwe ya adokotala pali mankhwala monga "Bromkriptin", "L-dopa", "Cyproheptadine", "Cabergoline" ndi ena. odwala ambiri amathandiza akuti "bromocriptine". Zotsatira ndi noticeable mwa masabata ochepa. Koma iye ali kwambiri mavuto, kotero njira yabwino 'Cabergoline. Komanso, n'zosavuta ntchito (magawo awiri pa mlungu).

The mankhwala yafupika chotupa kukula, ndi katulutsidwe wa prolactin amagwa masomphenya wabwinobwino, siyani kutayikira colostrum. Mu akazi a msinkhu wobereka reappear kusamba, ntchito ubereki wabwezeretsedwa. Amuna apitirira Kukhala wosabala, kubwerera libido.

Ngati, pambuyo njira yaitali kuti ndiyambe ndiwofatsa, zinthu sanasinthe bwino, kapena panali azimuth zoipa, ndi neurosurgeon ndi m'thupi yemwenso ndi zolowa alowererepo pa opaleshoni. Kwa odwala ndi contraindications opaleshoni, pali njira ina - radiotherapy. Koma zovuta: kukulitsa pituitary insufficiency, ndipo muyenera moyo wonse m'malo mankhwala.

Kudya prolaktinome pituitary umalimbana kuchepetsa kulemera owonjezera, amene anaonekera pa maziko kulephera m'thupi. M'thupi yemwenso kapena kadyedwe zingathandize dongosolo chakudya zimene zili zonse macro- zofunika ndi microelements, komanso kukhala okhutira mkulu wa kashiamu ndi phosphorous zofunika kupewa kufooka kwa mafupa. kudya zakudya zopatsa nthanzi, mukhoza n'kudziphatika kwa ndipo pambuyo matenda adzagonjetsedwa.

Chithandizo cha mankhwala wowerengeka pituitary prolactinoma si wofunika kwambiri ndi akatswiri monga infusions ndi decoctions musati kubweretsa zotsatira akufuna, koma pa nthawi yomweyo ziletsa ntchito ya chithokomiro ndi zopangitsa adrenal. Izi zingathe kusokoneza boma wodwalayo wathanzi, komanso maulosi za wolakwayo. Ngati kwambiri ndikufuna kuti alange ndekha maphikidwe agogo a, musaiwale dokotala.

Kuneneratu ndi kapewedwe

Ndingatani achire ku pituitary England prolactinoma? Zotsatira za ulimi kwambiri mahomoni m'thupi ndi chotero kuti, ngakhale chotupa wapita, anthu adakali yaitali kuti achire ntchito otaika. Komanso, madokotala musataye Zoneneratu aliyense za mlingo ayambe ndi bwino chithandizo.

Kuyambiranso amapezeka pafupifupi theka la odwala ndi pambuyo ziwerengero opaleshoni ngakhale m'munsi - peresenti makumi atatu okha a achiritsidwe.

Ndi chiganizo matenda "prolactinoma pituitary?" Zoneneratu kupereka zovuta. Chithandizo akhoza kutenga zaka ndipo musataye zotsatira. Pakangopita zaka, madokotala akulangizidwa yopuma pakati pa maphunziro a mankhwala kuthetsa impso ndi chiwindi. Koma pa nthawi yomweyo, kuchotsa mankhwala zingachititse chotupa chija ndi chotupa kukula.

Odwala kukhazikitsa kuvomerezedwa zachipatala kukayezedwa. Chaka chilichonse iwo uyenera kupanga kompyuta kapena maginito kumveka kulingalira ubongo, kukaonana ndi maso, gynecologist ndi m'thupi yemwenso ndi kuyesedwa kwa mlingo wa prolactin. Chotero bwinobwino, tikayerekezera ntchito pa nthawi, ndi kusintha yake ya mankhwala n'zotheka kuti ena zonena ayambe odwala.