Kolajeni - ndichiyani? Zizindikiro, matenda ndi mankhwala a matenda

matenda a "kolajeni" ndi amapezeka mankhwala amakono. Ndi chiyani icho? Ndipotu mawu amenewa amabweretsa pamodzi ambiri nthenda zosiyanasiyana kuti ali ndi chinthu chimodzi chofanana - kusintha mu minofu connective, monga zotupa kolajeni fibrinoid.

Ndithudi, odwala matenda ndi "zokhudza zonse connective minofu" amayendetsa mu mantha. Choncho, choyamba ayenera kudziwa zambiri za matenda amenewa ndi makhalidwe awo. Amene matenda ali mgulu la minofu connective? ndi zimayambitsa awo? Kodi zizindikiro ayenera kulabadira? Ndingatani kuchotsa matenda kolajeni muyaya? Kodi Zoneneratu kupereka madokotala? Mayankho a mafunso amenewa akufunafuna anthu ambiri.

Kolajeni: ndichiyani?

minofu Connective amadziwika kuti ngati kumanga mfundo thupi. Mwachitsanzo, ndipamene mafupa ndi khungu anthu, magazi chotengera makoma, ndi stroma ziwalo mkati, komanso amadzadza interstices pakati pa nyumba zosiyana. Ndi nsalu iyi, ndipo ana oposa theka la thupi la munthu. zinthu Connective ntchito zingapo zofunika, kuphatikizapo trophic, kuteteza, structural, chithandizo ndi pulasitiki. Ndi connective matenda minofu zimagwira mawu akuti "kolajeni".

Ndi chiyani icho? Izi gulu la pathologies kuti ndi makhalidwe ofanana ndi limagwirira ntchito za chitukuko. Matendawa akufotokozera pa maziko a kuyan'anila za homeostasis m'thupi ndipo limodzi ndi kusintha fibrinoid kolajeni.

Mitundu ya matenda kolajeni

mankhwala amakono kudziwika zosiyanasiyana kolajeni. Gawo lawo potengera chiyambi cha matenda. Mwachitsanzo, akakufunsani connective minofu matenda mwina kobadwa nako. gulu Izi zikuphatikizapo Stickler syndrome ndi Marfan ndi mucopolysaccharidoses ndi osteogenesis imperfecta. Zizindikiro za iwo amakonda kuonekera ngakhale utero.

Palinso matenda nzika kumawonetsera atabadwa - zina ana kapena unyamata, ndipo nthawi zina ngakhale mukadzakula. Izi pathologies gulu monga zokhudza zonse vasculitis, skerodermiyu, nyamakazi, misempha, eozinovilny fasciitis, periarteritis nodular, ndi ena ambiri.

The chikuchititsa mavuto a matenda

Nthawi matenda obadwa imakhudzana ndi matenda majini ndi kagayidwe ya kolajeni dongosolo. Monga likamanena anapeza matenda, pali chifukwa akhoza kukhala yosiyanasiyana, ndiponso kuphunzira njira ya kudwala akadali yayambika.

Asayansi timakonda kukhulupirira kuti chibadwa cholowa ali pafupifupi nkhani iliyonse. Koma matenda lingachititse zinthu zingapo. Mwachitsanzo, nthawi zambiri hule ndi malowedwe mu thupi la matenda tizilombo toyambitsa, kuphatikizapo tizilombo toyambitsa matenda mumps, nsungu, chikuku, chikuku, ndi zina zotero D..

zimayambitsa mwina kukakhala mahomoni kuti akamakula, mimba ndi kusintha kwa thupi, mimba ndi zina zotero. D. Palinso zinthu zina zimene zimayambitsa matenda akufotokozera. Kolajeni akhoza woterowu ndi maganizo amphamvu, zoopsa, utsogoleli mankhwala, undercooling amphamvu, insolation. Nthawi zina matenda akufotokozera pambuyo katemera.

The pathogenesis matendawa

Ngakhale zosiyanasiyana gulu la matenda, pafupifupi nkhani iliyonse, ndi kudwala akufotokozera mu chiwembu chomwecho. Pamene zotsatira za chinthu chimodzi, tilinazo wa chitetezo cha m'thupi, chifukwa mu mapangidwe maofesi yeniyeni mapuloteni, amene ndiye anakaika pa nembanemba serous ndi synovial, zikopa ziwiya. Pamaso pa maofesi m'thupi amakwiya kutukusira matupi awo sagwirizana wa zimakhala ndi. Choncho, chitetezo munthu amayamba kuukira connective yake minofu.

Against maziko a njira pamwamba ananena kuti ndinu ananena kusintha pathological wa zimakhala. Kumene, mtundu uliwonse wa matenda connective minofu ndi zinthu zenizeni. Mwachitsanzo, mu matendawa autoimmune yotupa ndondomeko zimakhudza khungu minofu ndi subcutaneous minofu, ndi yodziwika ndi kusintha periarthritis ziwiya nodosa.

Kolajeni: chithunzi ndipo ambiri matenda chithunzi

Kodi chithunzi matenda? Kodi zizindikiro limodzi ndi kolajeni? Zizindikiro Inde, zimasiyana malinga zosiyanasiyana matenda ndi malo ndondomeko yotupa. Komabe, zina wamba akhoza kuzindikiridwa.

Wodwalayo kulimbikira malungo mpaka madigiri 38. Odwala amadandaula kuzizira ndi thukuta kwambiri. Pali kufooka ndi utachepa ntchito. Mumakhala aliyense collagenosis mawonekedwe akufotokozera olowa ndi minofu syndrome, amene amakhala ndi olowa ululu, myalgia ndi arthralgia. zochita zina matupi awo sagwirizana, maonekedwe a khungu totupa, kupweteka m'mimba, dyspepsia.

Periarteritis nodosa ndi zochititsa

Kolajeni osiyanasiyana mu chikhalidwe, choncho ndi bwino kuganizira kwambiri mmene ndi katundu mitundu. Periarteritis nodosa amakhala ndi zotupa zigawo zonse zitatu za khoma chotengera. The ndondomeko yotupa nawo pafupifupi zotengera zonse za thupi.

Zizindikiro zimadalira wotani mitsempha ndi mitsempha anadabwa. Pamene izo zifika pa zotengera za impso, odwala zindikirani woyamba ululu, chosokoneza cha outflow wa mkodzo. Anaona oopsa ndi kupata kulephera aimpso. Pamene kutukusira kwa Mitsempha oziziritsa wodwalayo kukhala matenda osiyanasiyana a m'maganizo. A kotala odwala ndi periarthritis nodular anati mphumu.

Zokhudza zonse lupus erythematosus

Zokhudza zonse lupus erythematosus - aakulu zokhudza zonse connective minofu. Ndi chiyani icho? Izi matenda, amene anatsagana ndi zotupa za pafupifupi machitidwe onse limba. Kupezeka pa khungu mofiirira kutupa foci (pa nkhope, ali ndi malo khalidwe kwambiri masaya ndi mphuno chokhala ndi mapiko a gulugufe a).

Pali imfa ya tsitsi ndi misomali, ndi nembanemba mucous kuoneka chilonda komanso kukokoloka kwa nthaka. The ndondomeko yotupa ikukhudza mafupa ang'ono. Matendawa limodzi ndi matenda a dongosolo mtima ndi kupuma. Aimpso kudwala anaona ndi maonekedwe zizindikiro ubongo.

zokhudza zonse za matendawa

Matendawa - matenda ena autoimmune imene ndondomeko yotupa zimakhudza khungu, subcutaneous minofu, Mitsempha zotumphukira, mafupa ndi minofu. Pankhaniyi, zizindikiro odziwika ndi kusintha khungu chabe. Choyamba, pali kutupa kwa khungu. The dermis amakhala wotumbululuka kapena, Kapenanso, wofiira. Mu Chinthu chachiwiri kutupa matenda amakhala wandiweyani kwambiri, yosalala khungu la mtima ndi youma adhesions anapanga ndi zimakhala zakuya.

Chachitatu limodzi mwa manja a khungu ndipo zimakhala subcutaneous. la munthu wodwalayo ali wotopa, zala pang'onopang'ono olumala, nkhope zimatengera mtundu wa chigoba ndi chifukwa kutha kwa nkhope.

The ndondomeko matenda

Kodi matenda minofu? Kugonjetsedwa kwa matupi zosiyanasiyana limodzi ndi zikamera zizindikiro zenizeni kwambiri, ndi amene amakoka chidwi cha katswiri akulumikizana ndi wodwala ndipo anamnesis. Kenako, mumakhala zosiyanasiyana mayesero zasayansi. Makamaka, magazi mtima anthu mayesero pamaso pa zolembera si yeniyeni kutupa, ndicho fibrinogen, C-zotakasika mapuloteni, alpha-2-globulin. Ndipo kafukufuku amachitika pamaso pa chamoyo zolembera immunological kuti ali enieni matenda aliyense.

Nthawi zambiri, kuti asa- bwinobwino mmene wodwalayo, ndi biopsy imagwiridwa. Kutenga zitsanzo kwa kusanthula zimakhala minofu, khungu, impso, olowa synovium.

Pali zida kafukufuku kuthandiza kuzindikira matenda monga kolajeni. Matendawa zikuphatikizapo X-ray mosamala mfundo ndi mafupa. M'zithunzi dokotala sangathe kusunga makhalidwe ena matenda connective minofu, kuphatikizapo kufooka kwa mafupa, kusintha kali articular ndi aseptic necrosis, kuchepetsa wa ming'alu olowa ndi zina zotero. D.

Popeza kolajeni nthawi zambiri limodzi ndi zotupa za ziwalo n'kofunika ngati ultrasound wa pamimba, impso, ndi pleural M'mimbamo kwa mtima (echocardiography). Komanso anatumizidwa kompyuta kapena maginito kumveka tomography, amene amalola kuti asa- boma la chamoyo, komanso zinawonongedwa ndi ziwalo ndi mafupa.

mankhwala a matenda kolajeni

Amene mankhwala zimafunika kolajeni? Chithandizo cha matenda a gulu ayenera kukhala zovuta. mankhwala chiwembu wapangidwa payekha, monga izo zimatengera mawonekedwe ndi siteji ya matenda, kukhalapo kwa matenda concomitant, zaka wodwalayo.

Popeza kollagenozah anati kutupa kwa nyumba connective minofu, odwala choyamba Kwalamulidwa mankhwala odana ndi yotupa. Mu magawo oyambirira chitukuko ogwira sanali steroidal mankhwala, makamaka amene amatha ibuprofen.

Nthawi imeneyo, ngati matenda ili m'kati msanga kwambiri, mu chiwembu cha mankhwala kutumikiridwa glucocorticosteroids, ali yapadera kwambiri odana ndi yotupa katundu. Amagwiritsidwa ntchito "prednisolone" (pazipita tsiku mlingo palibe oposa 15 mg).

zotsatira zabwino akamagwira ndi mankhwala cytotoxic ( "Azathioprine", "Tsiklofofamid"). mankhwala otere kutumikiridwa ngati steroid sanapereke zotsatira anakhumba kapena anachititsa aakulu zosiyanasiyana chokhwima.

Chithandizo cha matenda pachimake anachita m'chipatala. Odwala anali nane kuchipatala patangopita adzatha kulimbana ndi zizindikiro zazikulu. Nkofunika kutsatira mode olondola a ntchito ndi ena, komanso kudya zakudya, osati pachimake komanso moyo.

njira zina zochizira

Kodi mankhwala amafuna kolajeni? Chithandizo n'kofunika osati pachimake komanso pa wachibale umoyo wa thupi. Pofuna amachepetsa mphamvu ya matenda, hemocorrection ntchito njira, makamaka hemosorbtion ndi plasmapheresis. Odwala ena mankhwala mankhwala thupi. Ndithu zotsatira zabwino chingapezeke mwa maphunziro nthawi zonse magnetotherapy, iontophoresis, phonophoresis.

Mu nyamakazi ndi matenda ena adzakhala zothandiza achire thupi, zimene zingakuthandizeni kukhala kuyenda bwinobwino. Odwala akulangizidwa zonse spa chithandizo mabungwe lolingana mbiri. Mu matenda a kolajeni umapangitsa wapatsidwa radon, sulfide hydrogen ndi malo osambira wa carbon dioxide. Ndithudi, chakudya tiyenera kuyesetsa ndi dokotala malingana ndi matenda mitundu, zaka ndi chikhalidwe cha munthu wodwala.

zodzitetezera ndi odziŵa za odwala

kolajeni matenda (ya mtundu wake) amakhala ndi mwapang'onopang'ono, Inde aakulu. mankhwala limachititsa kuchepetsa maonekedwe a matenda ndi kukwaniritsa kwambiri kapena zochepa yaitali chikhululukiro. Komabe, kusiya kwathunthu matenda kuli kovuta. Makamaka oopsa ndi zokhudza zonse kolajeni, amene amakhala ndi chitukuko cha kupuma pachimake kapena kulephera mtima.

Kutenga mahomoni ndi immumodulyatorov Ndithu zofunika. Koma odwala ayenera kuwunika ntchito za umoyo ndi chikhululukiro, izi zidzathandiza mwayi aggravation latsopano. Odwala ayenera analangiza kupewa kukhudzana ndi zinthu precipitating, kaya ndi maganizo amphamvu ndi disruptions m'thupi kapena hypothermia kwambiri ndi dzuwa kwambiri kukhudzana. Pamaso pa matenda alionse opatsirana, pomwepo kuchipatala. Foci kutupa aakulu komanso ndi amayamba mankhwala okwanira.