Segmented neutrophils - zokometsera wathu

Ambiri, kusanthula magazi chofunika masamu wbc, i.e. kuchuluka kwa magulu osiyanasiyana a leukocytes magazi. Ambiri mwa leukocytes mu wamkulu mu dongosolo akupanga neutrophils segmented (pafupifupi 70%). Iwo - ali mbali yaikulu.

maselo oyera anawagawa kuwiri mndandanda: granulocytes (granular) ndi agranulocytes (popanda mbewu). Granulocytes, amapatsidwa lophatikizana ndi ubwamunalo linagawanika mu neutrophils, eosinophils ndi basophils. Mtundu uliwonse wa selo uli ndi mbewu yeniyeni mu cytoplasm ndi amanyamula mbali yake yapadera.

Maselo onse a granulocytic motsatizanatsatizana chitukuko mu magawo a chitukuko cha myeloblasts, kupyola mu mndandanda wa maselo wapakatikati mwana anabaya ndi segmented leukocytes. Zimenezi zikugwira ntchito kwa mitundu itatu granulocytes - kuti neutrophils, eosinophils ndi basophils. Mu magazi zotumphukira zambiri imapezeka neutrophils kubaya ndi segmented. Maselo wamng'ono zili magazi mafupa okha matenda aakulu.

Kubaya neutrophiles mawonekedwe osiyana a phata selo. Phata woyamba ndi mosabisa, ofanana ndi Wand yokhota kumapeto. Phata chachiwiri lagawidwa kaduka apadera ambiri (2-4) zigawo. The cytoplasm maselo utoto pinki. Iwo ali abwino tirigu bulauni. Mu matenda opatsirana neutrophils graininess amakhala akuluakulu, ndi buluu (otchedwa toxigenic granularity). Ichi ndi chimodzi mwa zizindikilo za kutupa.

Ntchito, chimene anachita neutrophiles kubaya mu thupi kutetezedwa particles yachilendo, mavairasi, bowa ndi mabakiteriya. Granulocytes ndi ntchito phagocytic. granules amenewa ali enieni enzyme myeloperoxidase, anthu amamuona kuti zotsatira za zinthu antibacterial. Neutrophils angachititse mwachangu cholinga cha kutupa.

Ubwino segmented neutrophils ndi maselo ena mu leukocyte chilinganizo limafanana malamulo zaka. Choncho, ana osaposa zaka 5 chimakhala chogwidwa ndi lymphocytes ndi neutrophils ndi zosaposa 30%. chiwerengero cha gulu neutrophils ndalama wachibadwa 1-6%. The kuchuluka kwa neutrophils limodzi ndi matenda osiyanasiyana ndipo akutchedwa neutrophilia.

Childs neutrophilia silipita okwana kuwonjezeka leukocyte. Nthawi zambiri neutrophils kubaya kuchuluka kwambiri. Nthawi zina magazi matenda aakulu kuoneka mwana maselo - metamyelocytes (achinyamata) ndi myelocytes. Kuchuluka nambala ya maselo gulu, myelocytes ndi metamyelocytes maonekedwe otchedwa anasintha kumanzere kwa leukocytes. kosangalatsa chilinganizo kawirikawiri pamodzi ndi Kubwera kwa granularity toxigenic anabaya ndi segmented neutrophils ndi basophils cytoplasm awo.

asinthire ayende neutrophil pachimake yotupa matenda, limati mantha, infarction, osiyanasiyana intoxications. Makamaka kutchulidwa amasinthira ku lamanzere ndi aakulu myelocytic khansa. Mu matenda, segmented neutrophils ndi kuchepa zikuchepa monga kuchuluka ndi mawu mtheradi. Dongosolo amachuluka kubaya ndi maselo mwana. Kuchepetsa chiwerengero cha neutrophils segmented kumabweretsa mfundo yakuti zoteteza ntchito ya leukocytes amachepetsa. Linaopseza Kuwonjezera matenda osiyanasiyana.

Kuchepetsa neutrophils segmented ndi gulu amatchedwa neutropenia. Nthawi zambiri amapezeka pa maziko a kuchepa ambiri maselo oyera a m'magazi. Chotero boma amapezeka matenda aakulu ndi tizilombo, nthawi zambiri atalandira cytostatics, pambuyo mankhwala poizoni matenda magazi monga agranulocytosis ndi aplastic magazi m'thupi.

Choncho, udindo wa neutrophils segmented ndi kuteteza munthu ku matenda. Mu matenda chiwerengero cha ukuwonjezeka compensatory. Zimenezi zimaonekera kusintha chiŵerengero cha maselo chilinganizo magazi.