Syndrome "pebaldizm": kodi ndi osiyanasiyana, zizindikiro, matenda ndi mankhwala

Mmodzi zosiyanasiyana kagayidwe matenda pigment - ndichithu syndrome "pebaldizm". Gnozdnym yodziwika ndi discoloration tsitsi pa mutu wake. Izi si vuto lililonse zodzikongoletsera chilema, koma chizindikiro cha ambiri matenda aakulu.

M'nkhani ino tikambirana mwatsatanetsatane "pebaldizm". Zoyambitsa, zizindikiro, matenda, mankhwala, adzamva anafotokoza.

Zimayambitsa tsitsi oyeretsa

Kulakwila kagayidwe pigment ndi depigmentation - pigment imfa, hyperpigmentation - amveke kudetsa.

The tsitsi pigment ndi phindu 2 - eumelinin, pheomelanin. Iwo ali mu kotekisi tsitsi. Eumelanin zimapangitsa tsitsi lakuda ndi zofiirira pheomelanin - chikasu zofiira. Kuphatikiza inki izi chiwerengero munthu ndipo mogwirizana ndi mpweya amapereka tsitsi mtundu wina. Tsitsi ndi chibadwa analinganiza.

syndrome "pebaldizm" Kodi zimachitika, kodi matenda?

Kulakwila melanocytes, ndi pigment-synthesizing tsitsi, graying ndi zaka akufotokozera. Ngati chikhalidwe kumayamba ndili wamng'ono - umenewu ndi umboni wa matenda chibadwa, kapena matenda aakulu.

Matenda amene akuvutika pigmentary kuwombola

N'chifukwa chiyani "pebaldizm" syndrome, kodi zopatuka izi?

The limati izi zikukwaniritsidwa mu kuphwanya melanocytes ndi:

• pebaldizm mu mawonekedwe lakutali;
• alubino;
• pebaldizm pamodzi matenda diso, khutu, khungu, mantha dongosolo, minofu ndi mafupa dongosolo.

chithunzi matenda

Kodi izo kumaonekera "pebaldizm" syndrome, zikutanthauza chiyani?

Imfa ya pigment tsitsi mu mawonekedwe a maonekedwe a pindilani woyera pa mutu angayambe kwa mwana.

Mwamsanga pali kuphwanya kagayidwe pigment, ndi lalikulu kwambiri zotsatira chifukwa ankawonjezereka.

Wakutali discoloration potelani pamodzi ndi gawo la discoloration pamphumi panu. Limodzi ndi maonekedwe a foci wa hyperpigmentation, T. E. Gnozdnogo kunachita mdima wa khungu pa kutsogolo padziko pamimba, ntchafu, miyendo, chifuwa, mikono miyeso 1 mamilimita cm 6.

Disease obisalamo kumbuyo pebaldizmom

Pali gulu lalikulu la matenda ndi anomalies chitukuko, kaphatikizidwe pamodzi ndi oyeretsa tsitsi ziwalo kwambiri kuwonongeka ndi kachitidwe. Undiagnosed kudwala adzapulumutsa moyo wa mwana ndipo makolo kukapereka m'mavuto.

syndrome Waardenburg-Klein

Matendawa ndi autosomal chitsanzo lalikulu la cholowa, mwachitsanzo. E. The chomwecho nthawi zambiri amapezeka mu anyamata ndi atsikana. Chilema majini akhoza zochokera kwa kholo kapena.

Kuwonjezera pa oyeretsa a chingwe tsitsi ndi ananena ambiri ndi ocular kuwonekera kwa matenda.

Zizindikiro Ocular za matenda:

• hypoplasia wa nsidze ya;
• m'madera imvi pa nsidze mkati;
• yopapatiza diso kudula;
• osiyana maso wachikuda;
• hyperopia;
• ambiri spaced maso.

Zizindikiro Common kungakhale amawasonyeza mosiyanasiyana kwa mwamphamvu:

• tsankho alubino;
• yotakata m'mphuno mlatho;
• aafupi;
• anomalies mano;
• wogontha-mutism kapena akutali kumva imfa;
• anomalies ziwalo mkati;
• kusintha kukula Chibade cha.

Popeza kuti poyamba popereka matenda ndi kumachitika kokha osachepera pebaldizmom ayenera ndisanabadwe kuti achotse kudwala kwambiri. Ndicho chimene piebaldism.

syndrome Wolfe a

Wakutali heterochromia, T. E. A osiyana diso mtundu uli makamaka anapeza nyama. Anthu, pafupipafupi mwa anthu lonse ndi 1%.

Wotchuka anthu ndi maso mumtundu: chikats Kunis ( "oz The Great ndi Wamphamvu", "Bloodlines", "Jupiter Kukwera"), British Ammayi Jane Seymour, amadziwika kuti filimu "Live ndipo afe" Davide Bowie - British thanthwe woimba, songwriter, sewerolo, injiniya phokoso, wojambula, wosewera.

Wakutali heterochrony ndi matenda, ndipo osakaniza pebaldizmom matenda otchedwa Wolfe, ndipo akutitsogolera kuti ugonthi mofulumira kukula.

Kusiyanitsa matenda ayenera kukhala ndi retinitis pigmentosa - pigment epithelium dystrophy diso. Nthawi zambiri chimake Inde za matenda - retinitis pigmentosa popanda pigment.

Mayi ndi mwana wamkazi ndi matenda a "pebaldizm"

matenda ndi cholowa recessive, khromozomu-zogwirizana akazi. Mkazi akudutsa jini mwana wake, ndipo iye ali ndi matenda. Aakazi a anthu awa athanzi, ngati iwo ali ndi thanzi labwino. Zingakhale mawonetseredwe yekha wa pebaldizm.

Ngati mayi ali wathanzi kukomoka, koma ndi chonyamulira cha mbewu, mwanayo adzakhala akudwala.

Matenda pogwiritsa ntchito ophthalmoscopy, lomwe limatchula mawanga fundus mtundu ngati njenjete.

Gipomelanoz Ito

Matendawa akufotokozera chibadwire. Lolani ana a amuna ndi akazi ndi pafupipafupi ofanana. Osati kutsimikiziridwa kufala cholowa kwa makolo ana, koma matenda nthawi ndi nthawi pamodzi ndi olumala ziwalo mkati.

matenda wapangidwa kukomoka pamaziko zizindikiro zotsatirazi:

• awonekere khungu amelanotic mbali chodabwitsa mu mapini mawonekedwe, zidutswa za chipale chofeŵa;
• Pa palmar ndi, pamalo plantar ndipo zimagwira ntchito zosiyanasiyana mucous kusintha kumeneku sizichitika;
• m'dera zosatha siteshoni nsaluzi zinkangokhala tsitsi - pebaldizm;
• zaka depigmentation m'madera kukhala zochepa kuonekera;
• kuwonongeka kwa wamanjenje dongosolo zonse wasonyezera retardation maganizo, matenda convulsive, utachepa minofu kamvekedwe;
• kudwala kwa diso kuwonetseredwa strabismus amawasonyeza mosiyanasiyana kwa mwamphamvu;
• limodzi kupindika msana, chifuwa mapindikidwe m'makona 25% milandu;
• ndi pafupipafupi 10% pamodzi ndi zilema mtima.

Kusiyanitsa matenda ku chikhalidwe zofunika otchedwa pigment mkodzo. Iwo ali ofanana zizindikiro matenda, koma posachedwapa tinatengera.

pigment incontinence

Kodi matenda osowa imafalikira "pebaldizm"?

matenda imafalikira mayi wamkazi. Malinga ndi kukula kwa chithunzi matenda akuwonetseredwa ndi zizindikiro zotsatirazi:

• Ziwengo mu mawonekedwe a n'kupanga yaitali omwe, pambuyo kuyanika ndi kuchotsa crusts kusiya mbali mtundu. Kuphulika ndi njira undulating ndi maonekedwe nthawi ya maselo atsopano khungu. Anthu amenewa mwana ziwembu kusasitsa kutaya pigment ndi kukhala wotumbululuka.
• Dysplasia ndi dzino kasinthidwe, misomaliyo, tsitsi depigmentation monga alopecia ndi dazi.
• matenda a ubongo ndi kuwonetseredwa mochedwa psycho-kulankhula lobwera, kuchuluka intracranial kuthamanga, khunyu, kufooka mu manja ndi miyendo.
• matenda diso ndi wosakhazikika ndi kuwonetseredwa strabismus, nystagmus, ng'ala, yafupika masomphenya, khungu.

syndrome Gristselli

Izi ndi gulu la matenda kumene kungachitike mu njira zitatu, kufanana chachikulu ndi kukhalapo kwa yamawangamawanga discolored tsitsi pa mutu wake. The kusonyezedwa awa akupezeka:

• matenda a ubongo ndi hypopigmentation.
• Mtundu owopsa matenda amene "pebaldizm" syndrome zolumukizidwa ndi mkhutu hematopoiesis. Matenda mawonetseredwe: zolimbitsa thupi koopsa, paranormal ndi mankhwala. Mwamphamvu malungo pang'onopang'ono kumawonjezera, akulowa anawonjezera chiwindi, ndulu, kuchepetsa erythrocytes, leukocytes, maselo othandiza magazi kuundana, fibrinogen m'magazi. inawo zochitika pa njira ya ubongo.
• hypopigmentation wa khungu ndi tsitsi la osiyanasiyana mwamphamvu, zomwe mpaka ndiye atuluka popanda chiwonongeko wa maselo a mwazi ndi wamanjenje dongosolo. Pakuti matenda yake ya matenda oopsa ayenera kuonana ndi panthawiyi, dokotala dermatologist, chibadwa. Onetsetsani kuganizira kuli banja matenda osiyanasiyana a pigment kagayidwe, ndi kusanthula kuti achotse masinthidwe mbewu.

Mwachangu ndi chiopsezo cha matenda chifukwa pafupipafupi mkulu kaphatikizidwe ndi ozerezeka, Edwards, Turner.

Kupeza depigmentation wa khungu ndi tsitsi kungakhale pobadwa, koma kukhazikitsa pamaso pa matenda Turner akhoza kukhala monga munthu kukula kokha pamene amalembedwa aafupi, lymphostasis, matenda a mtima, kuthamanga kwa magazi, underdeveloped zopangitsa mammary, otsika udindo wa nipple ndi, m'malo ziwalo zoberekera connective nsalu. Intelligence odwala pafupifupi sajomba, maziko a maganizo nthawi kukwezeka, pali ena euphoria zabwino, lomwe limafotokoza wabwino anatengera chikhalidwe wa odwalawo.

Pomaliza

Anthu, jini ya mtundu wabwinobwino wa khungu ndi nthawi lalikulu poyerekezera jini amachititsa kuphwanya kagayidwe pigment.

Tanthauzo lenileni la mavuto ndi mtundu n'chakuti ndi zolembera yoopsa matenda chromosomal, malformations angapo kobadwa nako.

Aliyense kuphwanya kagayidwe khungu pigment, zikopa mucous, tsitsi ayenera kuonana ndi katswiri. Tafotokoza "pebaldizm" syndrome. Kodi izo, zinadziwika.