"Arthrosan": malangizo othandizira

Malangizo a "Arthrosan" pamagwiritsidwewo amatanthauza kachipatala ndi mankhwala okhudza mankhwala. Chinthu chofunika kwambiri cha mankhwalawa ndicho meloxicam, chomwe chimakhala choletsa kwambiri cha COX-2. Pansi pa dzina lakuti "Meloksikam" mankhwalawa amalembedwa mu inscriptions ya INN.

Pulogalamu yamapiritsi, mankhwalawa amapangidwa ngati mapiritsi olemera 7.5 kapena 15 mg, odzaza muzitsulo zamkati.

Malingana ndi mankhwala ake, mankhwalawa "Meloksikam", omwe amachokera ku enolic acid, amakhala ngati anti-inflammatory and analgesic agent. Njirayi imachokera ku luso la mankhwala pofuna kuletsa kaphatikizidwe ka prostaglandin. Pogwiritsidwa ntchito ndi mankhwalawa, zimachitika, pamene ntchito ya michere COX-2 yomwe imalepheretsa kutenga nawo mbali mu biosynthesis imaletsedwa.

Mukatenga mankhwalawa "Arthrosan" malangizowa akufotokoza zotsatira zake mwanjira imeneyi. Ngati mankhwalawa atchulidwa muyezo waukulu, ndiye kuti nthawi yayitali yayamba kugwiritsidwa ntchito kwa COX-2. Mankhwalawa alibe kanthu kochepa pa COX-1, yomwe imateteza chitetezo cha m'mimba. Ichi ndi chifukwa chochita zimenezi ndipo amateteza kachilombo ka zilonda zam'mimba.

Mchitidwe wotsutsana ndi kutupa kwa mankhwala "Arthrosan" malangizo ogwiritsiridwa ntchito amagwirizanitsidwa ndi kuchotsedwa kwa ntchito ya enzyme COX-2, yomwe imachitika pambali yotupa.

The pharmacokinetics ya Meloxicam ili motere. Kufalitsa: "Arthrosan" imatha kugonjetsa mu thupi lake hertogematic zolepheretsa, chifukwa chaichi kugwirizana kwa mapuloteni a plasma kufika 99%. Mu synovial madzi, ndende ndi 50%.

Metabolism: Mankhwalawa ali pafupi kwambiri ndi maselo a chiwindi, ndi kupanga mapangidwe angapo osalowerera ndale ndi mankhwala apamtima.

Chisamaliro: Mankhwalawa "Meloksikam" amatulutsidwa pafupifupi mbali zofanana mofanana ndi mkodzo ndi nyansi zochokera mumagetsi. Ndi 5% zokhazokha zomwe zimapangidwa kudzera mu matumbo.

Ma pharmacokinetic mankhwala a mankhwala "Arthrosan" malangizo ogwiritsiridwa ntchito amagwiritsanso ntchito milandu yapadera. Makamaka odwala okalamba ali ololedwa, mankhwalawa amachepetsedwa, ndipo pakakhala zizindikiro zowonongeka komanso zosafunikira, mankhwalawa alibe mankhwala ochepa pa pharmacokinetics.

Mankhwalawa "Meloksikam" amatengedwera bwino kuchokera m'magazi, pamene msinkhu wake umakhala wa 89% ndipo sukusintha kudya. Kubvomerezeka m'magazi opangidwa kumapereka mlingo waukulu wa mankhwala m'thupi.

Kufalitsa: Monga lamulo, zoyenera kwambiri Css amayenera kubwera tsiku lachitatu kapena lachisanu la kudya mankhwala, ndipo nthawi yayitali yogwiritsira ntchito mofanana ndi magawo oyamba a pharmacokinetic amaperekedwa.

Mlingo wokonzekera "Arthrosan" umatchulidwa mu malangizo omwe angagwiritsidwe ntchito motere.

Gwiritsani ntchito mankhwalawa akulimbikitsidwa mu mawonekedwe ophatikizidwa. Ndondomeko yotchuka:

- Pa gawo loyamba la chithandizo, kwa masiku 2-3, gwiritsani ntchito "Masukulu a Artrozan";

- patadutsa masiku atatu kapena anai a jekeseni wa mankhwala, mankhwalawa ayenera kutengedwa pamlomo - ngati mapiritsi.

Mlingo wa mankhwala osokoneza bongo ndi wamlomo ndi ofanana, ndipo umakhala wofanana ndi (7.5 kapena 15 mg) kamodzi pa tsiku. Mlingo ndi nthawi ya ntchito zimatsimikiziridwa ndi kukula kwa ululu ndi kuuma kwa kutupa. Pofuna kudziwa mlingo, muyenera kuganizira mosamala za chiopsezo chachikulu cha m'mimba.

Pamaso pa kulephera kwa nsana, mlingo wa tsiku ndi tsiku siposa 7.5 mg.

Kuyanjana ndi mankhwala ena kungakhale kovuta ndi zochitika za zozizwitsa zowonongeka m'magazi. Musamamwe mankhwalawa pamene mukuyembekezera komanso akuyamwitsa.

Mankhwalawa "Meloksikam" ayenera kusungidwa m'malo amdima kwa zaka zoposa ziwiri.

Mankhwalawa amagulitsidwa kokha pa mankhwala.