Mankhwala akuti "Vikeyra Pak". Reviews ankachitira, makamaka ntchito Viekira Pak

yokonza mbadwo watsopano wa chiwindi C "Vikeyra Park" ndemanga amaliona mu zosangalatsa. Ichi ndi chifukwa kwenikweni kwa dzuwa mkulu wa mankhwala.

The kanthu mankhwala "Vikeyra Pak"

The kanthu za mankhwala zachokera mitundu itatu ya mankhwala mavairasi oyambitsa. Izi "dasabuvir", "Ombitasvir" ndi ritonavir-ndinayamba "Paritaprevir". Pamene dziko odziwika mankhwala otchedwa "Harvoni", "Vikeyra Pak" chithandizo kwambiri zothandiza - ndi imeneyi kuchokera 97 mpaka 99%. Mankhwala kwa chiwindi ndi wachinayi ovomerezeka mu United States. Pamaso pake, mayesero matenda akwanitsa anapambana "Olizio" (dzina mu Russian - "Sovriad"), ophatikizana "Harvoni" ndi "Sovaldi".

General zokhudza mbadwo watsopano kukonzekera mankhwala

"Vikeyra Pak" (mayankho ankapatsidwa mpaka iwo achuluka kwambiri, popeza mankhwala anawalemba mu Russia yekha mu May 2015) wosindikiza Mlengi Irish ndi mmatumba mu United States. Mankhwala amagulitsidwa mwalamulo mu Russia, mungathe kulamula pa mankhwala aliwonse. Yogwira pophika medicament ndi:

• ritonavir;
• dasabuvir;
• paritaprevir;
• ombitasvir.

Zimatanthauza mankhwala mavairasi oyambitsa mwachindunji (J05A). Izi medicament - ndi mankhwala okwera mtengo. Mwachitsanzo, mankhwala masabata 12 ndalama 950 zikwi rubles - izi zikutanthauza angapo phukusi "Vikeyra Pak" (poyerekeza ndi St. Petersburg). Ogula ndemanga fotokozerani kuti, poyerekeza ndi odziwika "Harvoni", mtengo wa imene Ulaya 60 madola zikwi, mankhwala Irish zisanathe alipo kugula. Kwambiri bajeti njira pakati pa onse ndi mankhwala ofanana amatchedwa "Sunvepra" (mtengo - 400 zikwi rubles zochizira nthawi yemweyo).

Terms ndi zinthu yosungirako

Kumasulira kwathunthu lokonzekera "Vikeyra Pack" akhoza kuwerenga pa phukusi la mankhwala. Pitirizani ayenera kukhala mu malo kuwerengedwa ana pa kutentha osati kuposa 25 digiri Celsius. Musawachite mankhwala pambuyo lotha nyengo n'loonadi - zaka 2. mfundo zonse za chipatala "Vikeyra Pak": mtengo, malangizo ntchito, anthu enieni akukumana mankhwala ndi mankhwala amenewa mwachidule m'nkhani ino.

Ntchito "Vikeyra Pak" ndi zotsatira zake zoyipa

Kuvomereza mankhwala pansi review zochizira chiwindi C ndi kuchitidwa akamadya, ndi calorie kapena mafuta zili mankhwala ulibe kanthu. M'mawa ayenera kumwa mapiritsi awiri paritaprevira / ritonavir / ombitasvira, kuphatikiza chimodzi piritsi dasabuvir. Yotsirizira ayenera kudyedwa ndi madzulo. Odwala ena dokotala n'kukulemberani njira "Vikeyra Pack" molumikizana ndi "Ribavirin". Ngati mwasankha chabe mankhwala amenewa, "Vikeyra Pak" alandirika ku kuchuluka kwa mankhwala asanu ndi tsiku:

• m'mawa tsiku - wina wakuda ndi awiri kuwala piritsi;
• madzulo - mdima limodzi;
• kawiri patsiku "ribavirin" mu mlingo wa 500 mg.

Ntchito "Vikeyra Pak" (ndemanga monga ndemanga ndi akatswiri anakumana) ayenera kwenikweni anagwirizana ndi dokotala. Ngati wodwala akudwala co-HIV, mlingo kamwedwe ali yemweyo, kuphatikiza, kwenikweni - pa chakudya. Pa ma CD ndi palibepo zotsatira aakulu mbali sanaphe mankhwala. Ambiri zolakwika zotheka, malinga ndi ndemanga ndi malangizo - ndi:

• asthenia;
• kusenda zosiyanasiyana, kuphatikizapo pruritus;
• kutopa;
• kusagona tulo;
• nseru.

Chiwembu cha njira ya chithandizo

"Vikeyra Pak" chithandizo chiwembu zikuphatikizapo osakaniza mankhwala atatu, anayamba ndi kampani "EbbVay" kuphatikiza mtundu pharmacokinetic enhancer amatchedwa "Ritonavir" kwa mankhwala. kamwedwe mankhwala amene amachiza matenda a chiwindi C akapatsidwa zochizira matendawa (genotype 1a) osakaniza "Ribavirin". Inde ayenera kukhala osachepera zonse masabata 12. Pakuti genotype 1b ankachitira ofanana, koma popanda kulolerana wa mankhwala masika. Komanso, "Vikeyra Pack" (mayankho ankapatsidwa pansi chiwembu amayang'ana kuposa chidwi) anafuna chithandizo cha odwala matenda enaake kulipidwa. Inde - masabata 24 ndi "Ribavirin" chifukwa genotype 1a, nthawi zina - masabata 12.

Olimbikitsidwa ayankhe virological odwala (genotype 1a) ndi kusapezeka kwa matenda enaake anali kukwaniritsa 97% milandu, pamene 1b - 100% amalembedwa kuti kuphatikiza mankhwala unachitikira mtundu. Kulipidwa chiwindi matenda enaake SVR nditapatsidwa 95% (Therapy masabata 24) kwa genotype 1a, nthawi zina (1b) chizindikiro akuyandikira zana pa zana.

contraindications

Kukonzekera "Vikeyra Pak" (mavoti ankachitira kutsimikizira izo) ali, monga mankhwala aliwonse, nambala ya contraindications. Zikuphatikizapo zotsatirazi:

• decompensated chiwindi ntchito;
• hypersensitivity kuti ritonavir;
• hemoglobinopathies;
• imodzi anathamangitsa "ddI" mankhwala;
• mimba;
• kulandira zoletsa kanthu mwamsanga;
• kulandira inducers amphamvu.

Tikumbukenso kuti ntchito mankhwala amenewa kwa ana amene alibe atapeza zaka ambiri, ndi koletsedwa. Komanso ali osavomerezeka lactating akazi mankhwala chifukwa chosowa zoona zokhudza malowedwe a yogwira "Vikeyra Pak" mu mkaka wa m'mawere anthu. Onetsetsani mukufuna kusiya yoyamwitsa.

Chenjezo kutsatira

The Office US wa Quality Control mankhwala inanena kuti "Vikeyra Pak" ndi analogues, omwe amagwiritsidwa ntchito pofuna kuchiza matenda a chiwindi C kungachititse kuti kuwonongeka sizingasinthe chiwindi. Zimenezi ndi zoona makamaka kwa anthu olumala mu ntchito ya chiwalo chofunika kwambiri. Pachifukwa ichi, Mlengi wapanga kusinthidwa zina malangizo ntchito mankhwala.

Ngati amaona odwalayo Ndime ya mankhwala kumachitika kawirikawiri kutopa, chizungulire, mseru, ndipo nthawi zambiri pali kusanza, komanso anayamba kutembenukira khungu lachikasu, muyenera ndithudi kupempha thandizo akatswiri chifukwa chakuti pali mwayi kuwononga chiwindi. Siyani kumwa mankhwala popanda chilolezo cha dokotala anu Mulimonsemo n'zosatheka, monga izi zingachititse kukaniza thupi mankhwala ena, kumenyana chiwindi. The dokotala pachipatala ayenera kukhala nthawi kusunga mtima kuthetsa zizindikiro za ntchito chiwindi. Njirazi ndi monga:

• magazi kuchokera varices esophageal;
• ascites;
• kuwonjezera mlingo bilirubin;
• encephalopathy.

medicaments monga "Vikeyra Pak" amathandiza kuchepetsa kwambiri ndalama za matenda C HIV mu thupi la munthu, kuwonjezera, akhoza amachepetsa mphamvu ya matenda.

Dongosolo la mankhwala kwa chiwindi C

Katundu Viekira Pak mankhwala monga osakaniza Mlingo angapo mankhwala ena kuti ntchito limodzi ndi "Ribavirin" kapena ayi. mankhwala anali kulandila chithandizo cha odwala matenda chiwindi matenda enaake ndi aakulu chiwindi C. Musanayambe ntchito mankhwala funso, m'pofunika kudziŵitsa dokotala za zotsatirazi:

• kukhalapo kwa kachirombo ka HIV;
• ena chiwindi matenda, kuwonjezera chiwindi C;
• ntchito kulera, kuphatikizapo ethinyl estradiol.

Dziwani kuti nthawi zambiri mavuto mankhwala kuyabwa ndi mkwiyo wa khungu, kusagona tulo ndi tiwaphunzitse kusanza. Malinga ndi chisamaliro 2015 thanzi akatswiri mankhwala mankhwala otchedwa "Vikeyra Pack" anthu oposa 11 000.

Kodi aliyense ayenera kudziwa wodwala kulandira mankhwala?

Ngati wodwala amaloŵamo ndi 12- kapena 24 tsiku Inde mankhwala, sikutheka kuti asiye popanda chilolezo cha dokotala. Zimenezi zingachititse kuti zikamera kukaniza mankhwala ena anzawo. M'pofunikanso kukumbukira kuti ngati wodwala patsogolo siteji ya matenda chiwindi, "Vikeyra Pack" zingachititse limba kuwononga kwambiri, kuphatikizapo kulephera chiwindi. Onetsetsani kuti kupempha thandizo ku chipatala, ngati waona zisadzachitikenso zonse zizindikiro monga kusanza, chikasu sclera ndi, mwadzidzidzi osadziŵika kusowa chilakolako chowala chopondapo.

Asanayambe mankhwala oyenera, kumafunika kuwerenga malangizo. mafunso ayenera kukambirana ndi dokotala. Sungabisalire mfundo iliyonse za ukupeza, kuphatikizapo zotsatira akutulukira mbali ya wothandizila 'Vikeyra Pak ".

Kafukufuku chitetezo

kukonzekera Safety "Vikeyra Pack" anali ayesedwa pamaziko a deta ya wachiwiri ndi gawo lachitatu mayesero matenda pafupifupi 3,000 odwala kulandira mankhwala osakaniza "Ribavirin" ndipo popanda. Data ndikuganizira mu odwala matenda matenda enaake chiwindi. zochita chilango chochokera ntchito anali anamuona pa 20% ya milandu. Zizindikiro ambiri - ndi kunyansidwa komanso kutopa kwambiri. Anasiya mankhwala chifukwa cha mavuto% 1,15 chabe. Iwo anayambiranso zochita zawo pambuyo kusokoneza mankhwala - 1.4%. Chifukwa cha zochita zoipa za lake kwa mlingo mankhwala anachepetsedwa, "Ribavirin" 8% odwala.

Kusiyana kwa zimene lake kwa mankhwala ndi odwala ndi wopanda matenda enaake chiwindi anali anaona. Mu phunziro matenda ifeyo odwala amene anatenga "Vikeyra Pak" ndi wopanda "ribavirin". Chizindikiro yekha anachita mankhwala, mu nkhani iyi - zikamera wa kuyabwa pakhungu. Anasiya chithandizo chake% 0.4 okha, yopuma mankhwala yapanga za 0,6% odwala. Chitetezo ziyenera a mankhwala "Vikeyra Park" unachitika pa magawo angapo (ndi wopanda matenda enaake, ndi Kuwonjezera "Ribavirin" Ndithudi ayi) ndi m'kati mwa mankhwala ie, masabata 12 ndi 24.

Chiyerekezo mtengo "Vikeyra Pak" mu Russia ndi m'mayiko

Mu United States of America "Vikeyra Pack" Ndipafupifupi 84.000 madola (kuphatikizapo 12-day njira ya chithandizo), ndondomeko mitengo latsopano la Russia, m'mayiko ena ambiri European, n'chosiyana kwambiri.

Pa Websites osiyanasiyana pa Intaneti munakwanisa kuona ndalama zosiyanasiyana za mankhwala Irish. Pakuti mabungwe zachipatala Russia mtengo "Vikeyra Pak 'wothandizila ndi pafupifupi 300 zikwi rubles kwa mwezi umodzi chithandizo. M'kati 12-sabata kulipira za 850-900 rubles. Motero, anthu amapatsidwa mankhwala pa masabata 24, ayenera kugula mankhwala kwa chiwindi C ndi osachepera oposa 1.5 miliyoni rubles.