Mankhwala "Avastin" mu pochiza matenda a maso: ndemanga, malangizo ntchito ndi zikuchokera

Mu mankhwala, pali milandu pamene zipangizo anayamba zochizira matenda ena, zotsatira zabwino mu mankhwala a ena. Izi zimachitika chifukwa cha zinthu zatsopano zambiri pamaso mankhwala umalandira ogula. Izi zinachitika ndi mankhwala kuti zithandize mankhwala a zotupa khansa, yakuti "Avastin". Mu pochiza matenda a maso ndi ndemanga ya mankhwala anakakamizika ndikuganiza, chifukwa chimene ndi matenda ndi bwino kugwiritsa ntchito mankhwala.

"Avastin"

Imfa ya masomphenya - chimodzi mwa zinthu zomvetsa chisoni za makina kukalamba kwa anthu. M'mbuyo monsemu wa njira mu diso anali kovuta kulamulira, koma zaposachedwapa mu pochiza matenda a maso apeza zinthu kuti asiya kupewa chitukuko cha matenda oopsa mu khungu.

Chifukwa chaichi, magulu osiyana mankhwala ntchito Mwachitsanzo, ntchito ndi kupambana kwakukulu zochizira khansa wothandizila "Avastin" mu pochiza matenda a maso. Reviews odwala amatsimikizira kuti mankhwala ali ndi digiri yapamwamba ya dzuwa. Koma kuti mudziwe mmene othandiza, m'pofunika kuganizira limagwirira matenda diso.

zimagwirira chitukuko matenda

Imfa ya masomphenya ndi chifukwa kuchuluka nthenda ya capillaries magazi. Akutulukira ziwiya latsopano kukula Kakhungu, ndi kusokoneza dongosolo la diso. Komanso kuchuluka kwa mitsempha akapsa pafupipafupi kukha mwazi sipangakhalenso maganizo munthu kusintha khalidwe la masomphenya. Kuswa capillaries mabala, ndipo ambiri minofu connective kwa diso akuswa ndondomeko kudyetsa diso.

Mfundo tinganene kuti poyambira ya kuwonongeka kwa masomphenya. Chofunika, masomphenya amenewo pa chitukuko cha kudwala somatic si kwathunthu anatayika, ngati zotumphukira zambiri anapulumutsidwa. Komabe, khalidwe la moyo amachepetsa kwambiri.

Ngakhale kuti chithunzi cha matenda amayang'ana ogwetsa kwambiri, ndi matenda yake ya kudwala akhoza anasiya kusunga masomphenya. Chifukwa chaichi, ndi kugwiritsa ntchito mankhwala "Avastin" mu pochiza matenda a maso. Reviews odwala ndi madokotala anatsimikizira ziwerengero positive.

Kodi mankhwala

"Avastin" ndi anticancer wothandizira, izo ntchito Oncology kwa zaka zambiri ndipo akuwonetsa zotsatira zabwino. Momwe ntchito - m'kati kutsekereza zophuka minofu, nthenda magawano selo. Choncho, zinaloŵetsa pansi kukula kwa zipangizo zatsopano magazi kumatha zimayambitsa matenda palokha.

Kwa nthawi yaitali panali kukayikira ngati zingabweretse kufunika achire zotsatira Cancer mankhwala "Avastin" mu pochiza matenda a maso. Reviews asayansi ndi madokotala kuti kulemera maselo a pophika ake yogwira mopambanitsa: ndi pafupifupi katatu unyinji wa mamolekyulu mankhwala ena ndi mmene chomwecho. Choncho, chiphunzitso, mankhwala akhoza Musagonje retinal Kakhungu wosanjikiza, motero kupereka zotsatira achire.

Koma malinga ndi kafukufuku, "Avastin" mwangwiro likulowerera mu zigawo zonse kwa diso, kuchepetsa mlingo wa kuchuluka kwa capillaries magazi. Ndi matenda yake ndi mankhwala kuyamba kuti athe kusunga masomphenya.

zotsatira zoyipazi

Ngati tikambirana mankhwala "Avastin", malangizo ntchito, ndemanga ndi analogues ndi kofunikira kuti ntchito akulankhula yekha za phwando mkati, zomwe kawirikawiri amapezeka pa matenda a khansa. Choncho, mavuto a mankhwala ali motere:

• magazi mkati;
• oopsa;
• monyanyira kapepala kakuti m'mimba;
• proteinuria;
• dermatitis;
• neuropathy;
• asthenia.

Mndandanda wa zotsatira zoyipa ntchito mankhwala pa mankhwala lonse, monga pamene ntchito mankhwala aliwonse zochizira khansa.

Ntchito mu pochiza matenda a maso

Koma mu nkhani iyi mankhwala si kutumikiridwa m'nsinga, ndipo mwachindunji ku vitreous lapansi. Lachiwiri, mlingo n'chosiyana kwambiri chimene ntchito Oncology. Mwachitsanzo, jekeseni m'nsinga za 500 mg wa mankhwala, pamene diso - 1,25 yekha mg.

Komabe, wina mbali zotsatira za polandira "Avastin" alipo: magazi pa malo a jekeseni, moto kutengeka ndi concomitant womwetula. Palibe zizindikiro kwambiri chowawa akhala kuzindikiridwa kapena kafukufuku kapena kuchita.

dosing

1,25 mg wa mlingo chikuyendetsedwera mu thupi vitreous kamodzi pa mwezi, kapena katatu kapena anayi. Ndiye mukhoza amayang'anitsitsa zotsatira za mankhwala "Avastin" mu pochiza matenda a maso. Reviews odwala kusonyeza kuti atangotha njira ya kusintha acuity zithunzi anati 4 mwa 10 nkhani. Anthu 6 mwa 10 mankhwala kumabweretsa olimba maganizo, kapena kuti ndichepe mlingo wa kupitirira ndi kuchuluka kwa capillary amamuyambitsa timabala.

Zotsatira ndi kuti diso amakhala n'kakang'ono, ndiye kumawonjezera permeability ake ndi mphamvu ya diso minofu. Childs, wodwala akumva kusintha acuity zithunzi pambuyo jekeseni woyamba ndi jakisoni wotsatira kungangokulitsa zotsatira. kangati muyenera kubwereza jekeseni, malingana ndi thunthu la munthu. Malinga ndi kafukufuku, njira wotsatira wa jekeseni ikuchitika miyezi 2-3.

contraindications

mankhwala ndi mosamalitsa osavomerezeka chifukwa ana, amayi oyembekezera ndi azimayi unamwino. Komanso, osamala iyenera kugwiritsidwa ntchito "Avastin" kukachitika kuti pali chosayenerera chiwindi ndi impso, makamaka zinchito insufficiency ziwalo.

Koma tiyenera kuganizira mfundo yakuti contraindications awa ntchito kokha pamene kutumikiridwa m'nsinga, ndi popereka jekeseni mu diso, iwo alibe zoyenerera. Mulimonsemo, chosankha pa poika mankhwala "Avastin" mu pochiza matenda a maso ndemanga amene akhoza zopezera chipatala iliyonse yoyenera, dokotala ayenera kuchita.

Komabe, tiyenera kukumbukira kuti ntchito chakale mankhwala, madokotala mwamphamvu analangiza kudziteteza pofuna kupewa mimba zapathengo. Kugwiritsa ntchito mankhwala monga mankhwala kwa maso, nayenso, ayenera mfundo imeneyi, kuchita kulera.

analogs

Mu dziko njira kupulumutsa view ntchito kwa nthawi yaitali, koma chifukwa cha ichi ntchito mankhwala ena monga Macugen ndi Lucentis. Koma m'zaka zaposachedwapa pakhala maphunziro zambiri amanena kuti "Avastin" othandiza kwambiri pochiza matenda a maso. Koma bola ngati palibe nkhani zotsatira yaitali ntchito mankhwala zochizira diso, zidzakhala mwalamulo mankhwala zochizira zotupa khansa.

Pakali pano, mu Ikani-mawu silinenapo za mankhwalawa diso. Choncho yekha amawatenga pa ntchito ya "Avastin" mankhwala pochiza matenda a maso - ndemanga. Mtengo wa mankhwala ndi wokhulupirika ndithu, kupanga izo angakwanitse kwambiri poyerekeza ndi anzanu.

Mawu akuti "analogi" nthawi zambiri amanena kuti mankhwala amene ali ndi dongosolo zofanana, yemweyo yogwira pophika. Pa Russian msika mankhwala mankhwala kumeneko, sipangakhalenso anatsimikiza amayerekezera zikuchokera, popeza anaphunzira zikalata, zomwe zikuphatikizapo Ufumuyo mankhwala "Avastin" malangizo Buku. Analogues, ndi ranges mtengo kuchokera angakwanitse kuti mtengo ndithu, ndi mndandanda mofanana zizindikiro. Koma limagwirira womwewo wa kanthu chifukwa zigawo zina.

Mankhwalawa, amene angapezeke pa ogulitsa mankhawala iliyonse, monga:

• "Arzerra."
• "Atsellbiya".
• "Vectibix".
• "Herceptin lyophilisate".
• "Herceptin".
• "Campath".
• "MabThera".
• "Pereta."
• "Removab."
• "Rituximab".
• "Erbitux".

Zotuluka pa ntchito

Official mankhwala lero si amalangiza ntchito "Avastin" mu pochiza matenda a maso. Reviews odwala zambiri ndi zabwino, koma pali waukulu digiri ya chiopsezo, zomwe muyenera kudziwa.

Pali kutsutsana kugwirizana ndi mankhwala "Avastin": Malangizo ntchito pochiza matenda a maso (oimira ndemanga sayansi ndi zina komanso) salola ntchito ndalama pa matenda a maso. Mlengi wa mankhwala a boma akulengeza kuti ngakhale choyambirira kapena Baibulo generic wa mankhwala "Bevacizumab", opangidwa ku Russia sayenera kugwiritsidwa ntchito mu pochiza matenda a maso. Umboni wa zimenezi mungazipeze pa malo Roszdravnadzor.

Koma pa zinthu zina, monga malo wodzipereka kwa pochiza matenda a maso Kawiri kawiri mutha kupeza mmene mankhwala othandiza kwambiri matenda a maso. Ichi ndi chifukwa chakuti kafukufuku wa sayansi pa ntchito mankhwala inkachitikira ndi ikuchitika patali chotero, kusonyeza zotsatira zabwino. Komabe, pamaso pa mfundo zogwirizana ndi chitetezo chokwanira cha mankhwala pa maziko a dzuwa mkulu, malangizo ati atsimikiziridwe kuti azipezeka mu chigawo "Zisonyezero Ntchito".

Nthawi ntchito

Pa nkhani imeneyi, "Avastin" ntchito pokha pokha zadzidzidzi, pamene zina ndi imfa wathunthu wa masomphenya. Mu kuyesera, mmodzi wa zipatala ndi Russian anapeza kuti jekeseni wa "Avastin" sanali ndi zotsatira zoipa kwambiri, osati bwinobwino ndipo sanali kuyambitsa khungu. Koma odwala anadandaula akugwera ndi moto m'maso.

Motero, "Avastin" - kwambiri ogwira mankhwala zochizira zotupa khansa. Khalani anakhala kutenga "Avastin" mu pochiza matenda a maso mavoti odwala ndi ambiri positive. Koma pamene kusankha ayenera amachita ntchito mankhwala okhawo omwe anakonzedwa kuthetsa vuto linalake, makamaka mankhwala mankhwala msika kale pali zida wapadera kuti akhoza kuchepetsa kupitirira kwa matenda ashuga retinopathy ndi mawonekedwe yonyowa wa AMD.

Choncho, "Avastin" angagwiritsidwe ntchito pokha pokha kwambiri moyang'aniridwa pafupi zachipatala.