Mankhwala "Bactrim": malangizo ntchito ana. Kuyimitsidwa: kufotokoza, zikuchokera, ndi ndemanga

Kodi mlingo ndi zimene zinafotokozedwa mankhwala "Bactrim"? Malangizo ntchito, mtengo, ndemanga pa mphamvu ya chida ichi Adzaperekedwa pansipa. Inunso muphunzira za m'mene ndipo kodi zinthu sikutheka ntchito anati medicament, mungapereke kwa ana, ndi zina zotero. D.

Mawonekedwe ndi zikuchokera mankhwala ma CD

Kugula mankhwala akhoza kukhala zosiyanasiyana:

• Syrup "Bactrim" (kuyimitsidwa). Malangizo ntchito inanena kuti mankhwala yogwira chida ichi ndi trimethroprim ndi Sulfamethoxazole. Komanso kuyimitsidwa m'kamwa monga zigawo zina monga methyl parahydroxybenzoate, dispersible mapadi, polysorbate 80, propyl parahydroxybenzoate, sorbitol, madzi oyera, vanila ndi oonetsera nthochi. Chogulitsa a madzi bwino amabwera mu mitsuko, amene anayikidwa mukatoni ndi ngwanjula.
• "Bactrim" mankhwala. Ndemanga za "Bactrim" boma kuti zinthu zake kukangalika ndi trimethroprim ndi Sulfamethoxazole. Pamene zosakaniza zina ntchito ndi sodium docusate, sodium wowuma glycolate, magnesium stearate ndi povidone. Kugula mapiritsi oblong wa mtundu woyera akhoza kukhala contoured phukusi anaika makatoni.

mbali pharmacological

mankhwala "Bactrim" Kodi ntchito? Malangizo ntchito suspensions ndi miyala inanena kuti gulu wothandizila antibacterial omwe akusonyeza zotsatira synergistic.

Limagwirira cha zochita za zinthu zina yogwira, monga trimethroprim, ndi kutsekereza michere 2 akanika chilimbikitso mu chidulo sitepe kugawanika folinic. Mothandizana ndi Sulfamethoxazole zotsatira antibacterial a chigawo ichi chikuphatikizapo kuchuluka kwa tizilombo toyambitsa matenda (Haemophilus influenzae, Streptococcus, pneumocystis chibayo, meningococci, Morganella, staphylococci, tizilombo bowa, gonococci, Serratia, Escherichia coli, histoplasmosis, nsomba, plasmodia, Vibrio cholerae, tsitrobakter, Klebsiella, Listeria, chlamydia, pertussis Bacillus, toxoplasma, fecal enterococci, actinomycetes, Brucella, Enterobacteriaceae tizilombo toyambitsa matenda nocardiosis, Shigella, legionellosis , Matumbo yersiniosis, tularemia, coccidioidomycosis).

Pharmacokinetics

Kaya mankhwala imatsala, "Bactrim"? Malangizo ntchito (kwa kuyimitsidwa wa ana kumapambana) limati atalandira mankhwala mkati izo ndithu mofulumira odzipereka mu kapepala chapamwamba GI.

The pazipita magazi ambiri mankhwala atapeza pasanathe maola 2-4. ntchito zake antimicrobial anakhalabe kwa maola 7. Kulankhulana ndi mapuloteni Sulfamethoxazole plasma ndi 70%, ndipo trimethroprim - 44%.

Kusintha kwachilengedwenso zinthu zazikulu (kuti metabolites anafooka) ndi acetylation amapezeka m'chiwindi. Anthu, mankhwala ndi wogawana anagawira, ndi malowedwe mwa zopinga magazi minofu.

Mapapo ndi woipa mkodzo wa trimethroprim kuposa plasma. Koma secretions bronchial, prostate, komanso malovu, ya ndulu, ukazi, madzi msana ndi interstitial wa khutu pakati, mkaka wam'mawere, ndi mafupa a maso, imene medicament amasungidwa digiri wamng'ono.

Onse yogwira mankhwala kuwonongedwa mlingo ali yemweyo. Pa mphindi moyo wawo zimadalira zaka:

• ana mpaka chaka - 7 maola;
• ana a zaka 1-10 - maola 6;
• akuluakulu - maola 11.

Pamene chakhungu impso ntchito, komanso ukuwonjezeka okalamba theka moyo wa mankhwala.

Anasonyeza medicament kudzera impso (70% ya trimethroprim ndi Sulfamethoxazole ndi 30%).

zikuonetsa

Imene imafuna mankhwala "Bactrim"? Malangizo ntchito (kwa kuyimitsidwa wa ana - Njira) akusonyeza zizindikiro zotsatirazi:

• dongosolo kupuma: chibayo lobar, bronchiectasis, chibayo, Pneumocystis chibayo, pachimake kapena aakulu matenda.
• ENT ziwalo: chofiira malungo, sinusitis, media otitis, zilonda zapakhosi, laryngitis.
• Urogenital: amapatsirana, urethritis, prostatitis, pyelitis, lymphogranuloma venereum, cystitis, epididymitis, pyelonephritis, chinzonono, granuloma inguinale.
• dongosolo m'mimba: cholecystitis, paratyphoid malungo, gastroenteritis, typhoid, kolera, cholangitis, kamwazi, salmonellonositelstvo.
• Khungu: ziphuphu zakumaso, abrasions, matenda, mabala, pyoderma.
• Other pachimake brucellosis, yopweteka kwambiri kapena yokhalitsa osteomyelitis, malungo, matenda osteoarticular kudwala, toxoplasmosis (monga mankhwala adjuvant), ndi South America blastomycosis.

contraindications

Kodi contraindications ali pano mu "Bactrim" mankhwala? Malangizo ntchito (ana slurry anagulitsa yekha malangizo adokotala) inanena malamulo oletsa izi:

• leukopenia;
• hypersensitivity kwa zigawo zikuluzikulu za mankhwala;
• agranulocytosis;
• chiwindi kulephera;
• m'badwo wa miyezi itatu;
• aplastic magazi m'thupi;
• aimpso kulephera;
• B12-akusowa magazi m'thupi;
• Kuyamwitsa;
• akusowa shuga-6-mankwala dehydrogenase;
• pa mimba;
• Khanda hyperbilirubinemia.

mosamala wakuuzani

Mosamala kwambiri, mankhwala Kwalamulidwa kwa:

• porphyria;
• matenda a chithokomiro;
• bronchial mphumu;
• pakumwa folic acid akusowa.

Mankhwala "Bactrim" (kuyimitsidwa): Malangizo ntchito ana

Reviews za medicament uyu adzakhala pansipa.

Mlingo wa mankhwala ana ayenera kusankha yekha katswiri wodziwa. Kutsatira chofunika kuchuluka kwa kuyimitsidwa ntchito ngwanjula (5 ml), yopezeka.

Kuyambira ndili ndi zaka 12 mlingo "Bactrim" mankhwala ayenera 20 ml kawiri patsiku (m'mawa ndi madzulo). Ngati mukufuna mankhwala mosalekeza, madokotala amalangiza kumwa mankhwala, 10 ml m'mawa ndi madzulo tsiku lomwelo. Mu matenda kunachitika analola phwando madzulo ndi m'mawa Mlingo aakulu 30 ml.

pokonzekera "Bactrim" yaitali bwanji ana ndi matenda pachimake ntchito? Malangizo ntchito (kulongosola mankhwala inali kuperekedwa pamwamba) linati pansi matenda Kutalika kwa chithandizo ayenera kukhala masiku osachepera asanu, kapena mpaka mofulumira wathunthu zizindikiro zonse.

Chithandizo cha ana ndi zizindikiro za kusintha mkhalidwe wawo ndi nthawi amanena kwa dokotala kuti kusintha mlingo.

Mu matenda monga amapatsirana, yogwira medicament kutumikiridwa 20 ml ya kawiri pa tsiku. Ngati masiku 7 zizindikiro za machiritso, mankhwala akhoza anawonjezera sabata lina. Ziyenera adzanyamula kukumbukira kuti kupanda mankhwala akhoza kugwirizana ndi zikamera wa tizilomboto kukana.

Kodi kuchitira wopepuka pachimake mkodzo thirakiti matenda? Zimene limanena pa malangizo ntchito? "Bactrim" (madzi), amene ndemanga ali osokonezeka, kutumikiridwa kamodzi tsiku ndi kuchuluka kwa 40-60 ml. Landirani kuyimitsidwa makamaka pa nthawi yogona.

Pakuti kupewa chibayo ana kwa zaka 12 kupereka 20 ml ya mankhwala patsiku.

Mlingo wa mankhwala ana

ana akhanda 3-5 miyezi limasonyeza madzulo ndi m'mawa mlingo 2.5 ml ya madzi a. Kuyambira miyezi 6 mpaka zaka 5, ana anaika 5 ml lokonzekera, ndipo pa 6 ndi zaka 12 - 10 ml. Mu matenda akulu mwachindunji mlingo akhoza ziwonjezeke ndi theka.

zotsatira zoyipazi

Kodi mankhwalawo zingachititse mankhwala "Bactrim"? Malangizo ntchito (ana kuyimitsidwa - ngakhale kusankha mulingo woyenera, koma anatumizidwa yekha ndi mankhwala) akutionetsa zotsatirazi zochitika chowawa:

• leukopenia, neutropenia, agranulocytosis, megaloblastic magazi m'thupi, thrombocytopenia;
• m'mimba, kusowa chilakolako chakudya, kunyansidwa, gastritis, glossitis, kupweteka m'mimba, matenda a chiwindi, stomatitis, gepatonekroz, cholestasis, okwera chiwindi transaminases, pseudomembranous enterocolitis;
• kugwedeza, ulesi, litsipa, maganizo, chizungulire, aseptic meninjaitisi, neuritis zotumphukira;
• polyuria, interstitial nephritis, hematuria, matenda a impso ndi, hypercreatininemia, crystalluria poizoni nephropathy, milingo apamwamba urea;
• infiltrates m'mapapo mwanga, bronchospasm;
• kuyabwa, photosensitivity, exfoliative dermatitis, angioedema, zotupa epidermal necrolysis poizoni, exudative erythema multiforme, malungo, ankatenthetsa sclera, matupi awo sagwirizana myocarditis;
• arthralgia, myalgia;
• hypoglycemia.

ayamikira yeniyeni

Pamene totupa pakhungu kapena zina zosiyanasiyana chokhwima zachilengedwe katundu, chithandizo ndi mankhwala ayenera kusiyidwa.

Nthawi mankhwala "Bactrim" ayenera kukhala kochepa, mwinamwake ayenera kulamulira kuchuluka kwa zinthu aumbike mwa magazi.

Mu pakumwa folic acid akusowa, kulephera aimpso, ndi okalamba tikadwala kulingalira medicament mwina kuona hematologic kusintha chibadidwe kupanda kupatsidwa folic acid mu thupi.

Pofuna kupewa crystalluria wodwala ayenera kupereka zokwanira madzimadzi voliyumu ndi kuwunika diuresis chokwanira.

Ndemanga za "Bactrim" ana

Odwala kumwa mankhwala ankaona ngati kuyimitsidwa ndi piritsi, anafotokoza kuti mwapadera. Kwa anthu ena, mankhwala zinkaoneka kwambiri bwino ndipo wakhala chida chachikulu polimbana ndi matenda osiyanasiyana, ndipo ena - iyo imatchedwa zotsatira mbali.

Akatswiri kufotokoza ndemanga ngati wosanganiza chifukwa "Bactrim" amachita zambiri contraindications, komanso mndandanda waukulu wa zochita chowawa. Pa nkhani imeneyi, cholinga chake ndi zopindulitsa pokhapokha ngati mankhwala ena kapena kuthandiza wodwala.

Reviews wa madzi chimenechi zosiyanasiyana. Iwo saloledwa kuti maganizo yotsimikizika pa chitetezo ndi ubwino wa chidacho.

Malinga ndi malipoti a makolo, mankhwala ayenera kusankha dokotala, ndipo patapita bwinobwino kuchipatala. Only mu nkhani iyi, mankhwala adzakhala ogwira ndi wosavuta mwanayo.