Mapiritsi a Kombizpasm: malangizo ogwiritsidwa ntchito, maumboni, maumboni

Mafinya amatchedwa kusagwirizana kwapadera kwa minofu, yomwe nthawi zambiri imaphatikizidwa ndi kupweteka komanso kupweteka kwambiri. Akatswiri amasiyanitsa mitundu yambiri ya kugwidwa koteroko. Izi zimaphatikizapo ziphuphu zamatenda kapena mitsempha yosakanikirana (mwachitsanzo, ngati ziwalo za thupi zikumwalira) ndi mitsempha yosalala, yomwe ndi makoma amphamvu (mwachitsanzo, angina pectoris).

Mitundu yoyamba ya kugwidwa imalepheretsa kuyenda kwa munthu, ndipo yachiwiri - kumaphwanya ntchito za ziwalo za mkati.

Pochotsa ululu, ndi kubwezeretsa chikhalidwe chake, madokotala amalimbikitsa kugwiritsa ntchito mankhwala monga "Combizpazm." Malangizo ogwiritsiridwa ntchito, zizindikiro, mlingo ndi zotsutsana za mankhwalawa amaperekedwa pansipa.

Kuwongolera kwa mankhwala, kufotokoza kwake, mawonekedwe a kumasulidwa ndi ma phukusi

Kodi mumalandira mankhwala otani Kombizpazm? Malangizo ogwiritsira ntchito amanena kuti mankhwalawa akupezeka mu mapiritsi opanda chipolopolo. Zili ndi mawonekedwe ozungulira, zoyera ndi zoopsa.

Mmene mankhwalawa aliri mumaphatikizidwe ndi paracetamol, magnesium stearate, dicycloverine hydrochloride (i.e., dicyclomine), wowuma chimanga, methylparaben, talcum, povidone, sodium wowuma glycolate, propylparaben ndi colloidal silicon dioxide.

Mankhwala Kombizpazm, malangizo omwe atsekedwa m'bokosi la pepala lolemetsa, amamangiriridwa m'mabirat a mapiritsi 10.

Zotsatira za mankhwala (pharmacology)

Kodi zotsatirapo zotani pa wodwalayo ndi mankhwala Kombizpazm? Malangizo ogwiritsidwa ntchito, lipoti lofotokozera kuti uwu ndi mankhwala osakaniza omwe ali ndi zotsatira za antispasmodic ndi analgesic. Komanso, mankhwalawa ali ndi antipyretic, myotropic ndi anticholinergic.

The paracetamol, yomwe ili mbali ya mankhwala, ndi mankhwala osakanikirana ndi mankhwala osapsa. Ili ndi analgesic ndi antipyretic katundu. Cholinga ichi chimalepheretsa kaphatikizidwe ka prostaglandins, komanso amachepetsa kuchuluka kwa zotsatira zake pa malo opangira mafuta, omwe ali mu hypothalamus (ubongo).

Malinga ndi dicyclom, imathetsanso minofu ya minofu yosalala ndi kuchepetsa kupweteka kwa ululu. Mofananamo ndi paracetamol, chophatikiza ichi chiri ndi myotropic, antispasmodic ndi anticholinergic effect.

Kodi dicyclomine amathandiza bwanji pokonza "Combibispasm"? Malangizo ogwiritsidwa ntchito (momwe mankhwalawa akugwiritsidwira pamwambapa) amavomereza kuti gawoli likuchita molingana ndi mfundo ziwiri zosiyana:

1. Mofanana ndi atropine, pamene imachita acetylcholine kapena cholinergic receptors.
2. Kutsogolera mwachindunji pa minofu yosalala. Izi zimapangitsa kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda timapangidwe ndi bradykinin ndi histamine, komanso syndromes zopweteka kwambiri, zimachepetsanso mpweya wa m'mimba, zimachepetsanso kusungunuka kwa zilonda zam'mimba.

Tiyeneranso kukumbukira kuti pokhapokha ngati palacacamamol, ntchito ya dicyclomine imakula kwambiri.

Zizindikiro za mankhwala

Kodi zizindikiro zamakono za mankhwala Kombizpazm ndi ziti? Malangizo ogwiritsiridwa ntchito akudziwitsani kuti mutatha kumwa mankhwala mkati mwake, zomwe zimagwiritsidwa ntchito zowonjezera zimangowonjezereka mu kapangidwe kakang'ono kakang'ono ka chakudya ndikulowa muyeso.

Chidule cha mankhwalawa m'magazi chikufikira pambuyo pa mphindi 35-65. Pafupifupi 10% mwa mankhwalawa amamatira mapuloteni a plasma.

Mu matenda a chiwindi, paracetamol imagwira ntchito zamagetsi, ndipo imagwiritsa ntchito pulogalamu ya cytochrome P450.

Moyo wa hafu ya mankhwala omwe akugwiritsidwa ntchito ndi 120 minutes. Amadonthozedwa kupyolera mu impso.

Dicyclomine imatha kufika pamtunda wake m'magazi pambuyo pa mphindi 65-125 mutatha ulamuliro. Theka la moyo ndi 1.9 maola. Pafupifupi 70 peresenti ya chigawo ichi chimatulutsidwa pamodzi ndi mkodzo, ndi zina zonse - kupyolera m'magazi.

Zizindikiro za kumwa mankhwala

Kodi ndizochitika ziti zomwe Kombizpasm imapatsidwa? Malangizo ogwiritsidwa ntchito (mapiritsi - iyi ndiyo njira yokhayo ya mankhwala awa) amadzinenera kuti mankhwalawa akulamulidwa chifukwa cha ululu wosiyana:

• Ndi radiculitis, rheumatism ndi neuralgia;
• Ndi minofu, mutu kapena dzino la dzino;
• Kupumula kwa kupweteka kwa msambo komanso colic renal.

Zotsutsana ndi kugwiritsa ntchito mankhwala

Kodi mankhwalawa Kombizpazm amatsutsana? Malangizo ogwiritsidwa ntchito (mapiritsi a ululu wosiyana siyana ayenera kuuzidwa ndi dokotala wodziŵa zambiri) amadziwitsa kuti mankhwalawa ndi oletsedwa kuti agwiritsidwe ntchito pamene:

• Glaucoma, kumwa mowa mwauchidakwa, kusokoneza ubongo;
• Ali ndi zaka zoposa zisanu ndi ziwiri;
• Anemia, myasthenia gravis, leukopenia ndi tachycardia;
• Matenda a magazi, matenda aakulu mu ntchito ya chiwindi ndi impso;
• Mimba;
• Kuwopsa kwa zigawo zothandizira mankhwala;
• Hyperbilirubinemia (congenital);
• Kulephera kwa mavitamini a G6PD;
• Kuyamwitsa;
• Matenda osokoneza a m'magazi;
• Chilonda cha m'mimba ndi 12-coloni;
• Kusungidwa kwa mkodzo, komwe kumawonedwa ndi benign prostatic hypertrophy;
• Kutsekera m'mimba.

Kombizpasm: malangizo ogwiritsidwa ntchito

Mapiritsi, mtengo wake womwe uli pansipa, uyenera kutengedwa pamlomo, kutsukidwa pansi ndi madzi omveka. Mankhwala a mankhwala ndi mlingo wa mankhwala ayenera kutsimikiziridwa ndi dokotala.

Kwa ana kuyambira zaka 15 ndi akulu akulu mankhwalawa amapatsidwa mapiritsi awiri kapena kamodzi patsiku.

Chithandizo chimayamba ndi miyala iwiri patsiku. Patsiku, mankhwalawa sangatengedwe oposa asanu ndi atatu (popanda kusokonezeka).

Kwa ana a zaka 7 mpaka 13, mankhwala omwe amalamulidwa amalembedwa piritsi limodzi patsiku (magawo awiri), ndipo ali ndi zaka 13 mpaka 15 - mapiritsi atatu patsiku.

Kutalika kwa mankhwala ndi mankhwalawa kumatsimikiziridwa payekha.

Zikanakhala kuti kusintha sikukuchitika pakadutsa masabata awiri mutangoyamba kumene mankhwala kapena ngati mankhwalawa sakuwoneka, mankhwalawa ayenera kuimitsidwa.

Zovuta zochitika

Mankhwalawa "Kombizpazm", malangizo omwe ntchito ikufotokozedwa pamwambapa, amalekerera odwala. Kukula kwa zotsatira zosafunika kungagwirizane ndi kugwiritsa ntchito mankhwala osagwiritsidwe ntchito mosalekeza.

Wodwala akhoza kuwonetsa:

• Kutsekemera pakhungu, kuchepa kwa chilakolako, matupi, kusanza, kufiira kwa khungu;
• Kuwonjezeka kwa gassing, paresthesia, nausea, urticaria, mantha, kutsegula m'mimba;
• Kugona, kudzimbidwa, kusowa kwa ziwalo za thupi, kutaya mtima;
• Chizungulire, bradycardia, kusokonezeka maganizo ndi maganizo, kusokoneza maganizo, kuchepa kwa mawu, kuwonjezeka thukuta, chisokonezo;
• Tachycardia, kutayika bwino m'mlengalenga, kuchuluka kwa mtima;
• Matenda a hypoglycaemia, kupweteka kwa m'mimba, kufooka kwakukulu, kuopsa kwa chiwindi;
• Kufooka kwa minofu, glomerulonephritis, colic yamphongo;
• Matenda a anorexia, khungu louma ndi mazira, asphyxia, chisokonezo cha kukoma, kusokonezeka kwa minofu, apnea ndi mapuloteni a mmero.

Komanso kawirikawiri zimawuka:

• Ntheroroxic action, hemolytic anemia, pancytopenia, kutsekemera kwachibwibwi, neutropenia, kusagwedeza kwa mkodzo, kupuma kwa magazi;
• Thrombocytopenia, papillary necrosis, leukopenia;
• Matenda a Stevens-Johnson, methemoglobinemia, poizoni epidermal necrolysis, kutaya chidziwitso, kusintha kwa anaphylactic, kusowa mphamvu, ndi edema ya Quincke.

Chifukwa cha kukhalapo kwa dicyclovirin kwa wodwala, pangakhale kuwonjezeka kwa kupanikizika kwa m'mimba, kupititsa patsogolo kwa ophunzira komanso kuwonjezeka kwa kuzindikira. Komanso ziwalo za malo okhala ndi mydriasis n'zotheka.

Mtengo wa mankhwala ndi ziganizo zake

Kodi mankhwala akuti "Combibaspism" amawononga ndalama zingati? Malangizo ogwiritsidwa ntchito (mtengo wa mankhwalawa uwonetsedwa pakalipano) samayankha funso ili. Mudzaupeza mu pharmacy okha.

Mtengo wa mapiritsi 10 a mankhwala omwe ali mu funsowo ndi pafupifupi makoswe 100.

Ngati ndizofunika, zingatheke m'malo mwa mankhwala monga Trigan-D, Diklo-p, Bolo-ran Neo, Cefekon, Sedalgin Neo, Solpalgin, Dolaren, Kaffetin , "Novalgin", "Spasgo", "Dollar", "Sigan-DBS", "Apap", "Solpadein", "Solpadein", "Yunispaz", "Paracetamol".

Kuwonetsa kwa Wotsatsa

Tsopano mukudziwa momwe mankhwala a "Combizpasm" amagwirira ntchito. Malangizo, ntchito, ndemanga za chida ichi zikufotokozedwa m'nkhaniyi.

Ambiri ogula amanena kuti mankhwalawa akuwonekera ngati antispasmodic komanso analgesic. Zimathandiza kulimbana bwino ndi ululu wosiyana siyana, kuphatikizapo zomwe zimawonetsedwa pa nthawi ya kusamba kwa akazi. Mankhwalawa amatha msanga kupweteka mutu.

Kuphatikiza pa kukwera kwapamwamba, ubwino wa mankhwalawa umaphatikizapo kupezeka kwake (kugulitsidwa pafupi ndi mankhwala onse), komanso mtengo wotsika.

Zokhudzana ndi zofooka, zimachitanso. Odwala ena amadandaula za poizoni wambiri wa mankhwala, kumverera kwa kupweteka kwa lilime ndi mavuto ndi ziwalo za m'mimba.