Zamchere phosphatase: ponseponse kwa akazi, amuna ndi ana. Zamchere phosphatase mu mwazi: ponseponse ndi kupatuka

Zamchere phosphatase ndi puloteni yeniyeni, umene uli gulu la hydrolases. enzyme Izi zingaoneke m'madera onse a m'thupi la munthu.

Makamaka anagawira enzyme mwakhama osteoblasts, matumbo mucosa chipolopolo, mu England mammary, nsengwa, ya ndulu ducts mu mpanda.

Mitundu ya phosphatase zamchere

Phosphatase lagawidwa mitundu ingapo:
- placental;
- impso;
- chiwindi;
- E .;
- fupa.

Zamchere phosphatase, komanso michere onse yofanana ndi iyo, tiyenera pochitika zinthu zosiyanasiyana mankhwala mu thupi la munthu. Amafuna osachepera kuchuluka kwa phosphatase zamchere kuchita motero. Ndipo ngati thupi ali zakusokonenezedwa, izo zingatanthauze kuti zamchere phosphatase kuchuluka. Zifukwa kuenjezera enzyme izi zikhoza kukhala zosiyana kwambiri.

Kodi zamchere phosphatase

enzyme uyu akuchita zimene defosfolirovaniya. Zimenezi tichipeza mu pogawanikana pamawere a mankwala ku zinthu organic unachitikira pa mlingo maselo. Zamchere phosphatase m'magazi ali ndi zonse zina ndende. The puloteni amatha posamutsa phosphorous mwa selo nembanemba. Komanso, phosphatase - muyeso wa malamulo a kagayidwe kashiamu-phosphorous. Ntchito chachikulu cha enzyme ndi zikusonyezedwa pH sing'anga osiyanasiyana 8,6-10,1. Choncho dzina - ndi zamchere.

Zamchere phosphatase m'magazi

Osiyanasiyana adziwe milingo yachibadwa magazi a phosphatase zamchere mwachilungamo lonse. Kuwerenga zimasiyana 44 IU / L kwa 147 IU / L. Sayenera yomweyo mantha ngati zamchere phosphatase kuchuluka. zifukwa n'losavulaza kwathunthu. Mwachitsanzo, mlingo mwa amayi apakati nthawi pang'ono anakokomeza. Iye kukambapo ndi achinyamata, amene anatsegula siteji ya kutha msinkhu. Zonsezi chifukwa kukula kwa nsengwa ndi fupa, ndi silimanena zosiyanasiyana kuvutika mu thupi la munthu. Komanso kuzilingalira phosphatase zimadalira msinkhu ndi kugonana kwa munthu.
Pa nthawi palibe njira yovomerezeka, kotero kusuntha magawo ponseponse zimadalira reagents kuti ntchito mu zasayansi kafukufuku.

Zamchere phosphatase. wakudziko

mwina kwa kudziwa kuvutika mu thupi zamchere phosphatase. Ponseponse kwa akazi, amuna ndi ana pang'ono osiyana, tisaiwale. Mlingo wa puloteni imeneyi mu thupi akazi ndi pang'ono poyerekeza mlingo kwa amuna. Ngakhale ana chizindikiro cha mlingo wa puloteni imeneyi ndi wamkulu kuposa akuluakulu.

Mlingo wabwinobwino wa phosphatase zamchere mu ndi madzi a m'magazi a mwanayo ndi:

- makanda: 245-255 IU / L;
- ana azaka 1 mpaka zaka 9: 345-355 U / L;
- ana azaka 10 mpaka zaka 15: 275-285 U / L;
- achinyamata zaka 16 mpaka 19: 145-155 U / L.

Ponseponse kwa amuna:

zaka zaka 21 mpaka 30 - 100-110 U / L;
- zapakati pa zaka 30 mpaka 45: 110-120 U / L;
- zapakati pa zaka 46 mpaka 54: 120-130 U / L;
- zapakati pa zaka 55 70: 135-145 U / L;
- zaka '71: 180-190 U / L.

Akuluakulu, malingana pansi, chosiyana pang'ono zamchere phosphatase.

Ponseponse kwa akazi:

zaka zaka 21 mpaka 30 -: 80-90 U / L;
- zapakati pa zaka 30 mpaka 45: 90-100 U / L;
- zapakati pa zaka 46 mpaka 54: 105-115 U / L;
- zapakati pa zaka 55 70: 125-135 U / L;
- zaka '71: 155 -165ed / l;

Ndizachidziwikire kuti amuna ndi ulemu ndi lipoti akazi, pang'ono okwera zamchere phosphatase. Ponseponse kwa akazi ndi zosakwana mlingo anthu pafupifupi 20 U / L.

Chifukwa mitengo kuchuluka kwa phosphatase zamchere

Izo zanenedwa, chimene chimadalira pa phosphatase zamchere. Norma ndi chinawonjezeka, ndipo zimenezi si angabweretse chiopsezo thanzi. Koma zimachitika ndi mosemphanitsa, pamene kuenjezera index ndi chenjezo choyamba ndi zolondola mu thupi la wodwalayo ali anaona kuyan'anila kwambiri.

Pa kuwonjezeka mu lipoti la enzyme zingakhudze:

Pa mbali ya thirakiti biliary ndi chiwindi:

- chotupa cha ya ndulu ritsa;
- matenda a chikasu ndiyo, yomwe INGATHE kuyambitsa kutsekeka kwa ducts ya ndulu;
- khansa chiwindi;
- amamuyambitsa timabala wa ducts ya ndulu, chikwiyire ndi njira opaleshoni;
- miyala ducts ya ndulu;
- khansa ya m'mimba kapena kapamba;
- matenda enaake;
- opatsirana mononucleosis;
- aliyense chiwindi chiyambi. Mu matenda zimenezi mu 3-pindani kuchuluka phosphatase zamchere.

zifukwa pa gawo la fupa akhudzidwa:

- matenda Paget a. Matenda amakhala ndi nthenda kukula fupa, komanso kusokonezeka pa zinthu zina dongosolo fupa. Mu matenda, pamenepo pali milingo mkulu wa enzyme pansi kulingalira;
- fupa chotupa;
- osteosarcoma, amene ali ndi chotupa chotupa pa fupa;
- osteomalacia chikwiyire ndi kashiamu akusowa (osteomalacia).

zifukwa zina:

- m'mnyewa wamtima infarction;
- hyperparathyroidism, amene ali ndi matenda m'thupi, pamene anaona ndi muyeso wa timadzi parathyroid, parathyroid anapanga. Chifukwa cha chimene leaching kashiamu kwa mafupa;
- matumbo perforation (kudzera-kuwonongeka);
- anam'peza matenda a m'matumbo.

Chifukwa pamlingo wochepa wa phosphatase zamchere

Si ankaona kupatuka ndi kukwezeka zamchere phosphatase. Ponseponse kwa akazi ndi amuna zingachititse kuti mogwirizana ndi pansi.

A milingo kugwa phosphatase zingakhudze:

- magazi pa mlingo waukulu;
- magazi mu chaukali;
- hypothyroidism (otsika chithokomiro ntchito);
- gipofostataziya (kobadwa nako osowa matenda kuti akapsa ndi olimbikitsa mafupa);
- osakwanira ndalama nthaka ndi magnesium mu thupi;
- kulephera kwa latuluka (mu amayi apakati).

Kodi zimakhudza zotsatira

Kuonjezera:

- Pa mimba, ndi latuluka lili phosphatase zamchere. Ponseponse kwa akazi mu nthawi iyi si kukhala kwambiri;
- pambuyo fractures ananenanso kochulukira mlingo wa phosphatase zamchere;
- popeza ana ndi achinyamata wakhala kwafalikira mafupa, mlingo wa enzyme chinawonjezeka mlingo wa zokambirana;
- kuwonjezera mlingo wa phosphatase magazi angathe kukhala ndi mankhwala ena, monga "Paracetamol", "ndi aspirin", "Allopurinol", mankhwala osiyanasiyana, ndipo zosiyanasiyana mankhwala ena;
- deta enzyme defosfolirovaniya mlingo okwera zingaoneke, pambuyo yozizira, anatengedwa pa kuyesa kwa magazi.

Pa kutsitsa mlingo wa enzyme zimenezi zikhoza kulera m'kamwa.

Analysis kwa phosphatase zamchere

Panthawi kutenga kusanthula phosphatase zamchere mu magazi seramu woperekayo zimawonjezera reagents yeniyeni kuti adzatani phosphatase lapansi. Kenako, pogwiritsa ntchito njira yeniyeni, anthu ambiri mankhwala analandira chimaonekera. Aliyense minofu, zikhale intestine, chiwindi kapena latuluka, muli mtundu winawake wa phosphatase zamchere. Pa kusanthula ndende mpandawo cha enzyme yeniyeni.

Kuti pobwezera kusanthula chitsanzo magazi enzyme, wodwalayo adzafunika mphindi zochepa. Nthawi zina, anthu m'matumbo atatha kudya kwambiri opangidwa zamchere phosphatase. Pankhaniyi, zotsatira kusanthula zinthu molakwika. Choncho wodwala kutenga chakudya kapena kumwa madzi pamaso yobereka kuwunika.

Ndiyamika njira zamakono choyezera, zotsatira anadzakhala akusasanyika pambuyo maola angapo.

Yachokera pa kafukufuku onse, tinganene kuti phosphatase osachepera zamchere m'magazi - ponseponse. Kuwonjezeka mlingo wa enzyme izi zikhoza ngati chenjezo zolakwika kapena kuyan'anila, ndipo alibiretu kalipokalipo. Mulimonsemo, si chizindikiro chotsiriza cha kusintha kwa thupi.