Zifukwa pathogenesis ndi zizindikiro za gout

Mu gulu limodzi la matenda enaake ophwanya monga otchedwa microcrystalline kapena kagayidwe kachakudya nyamakazi. Mmodzi wa awa ndi gout nyamakazi, zizindikiro ndi kuwonekera kwa amene kale kuyambira Hippocrates. matenda Izi zimachitika chifukwa chakhungu kagayidwe asidi uric ku nkhani yake yapamwamba mu magazi, komanso pathological mafunsidwe a mibulu (urate) mu zimakhala ndi. Choncho zizindikiro gout kukomoka kuwonetseredwa zosayembekezereka wa pachimake nyamakazi, ndi mapangidwe tophi, gouty mfundo zenizeni.

Agiriki anapereka dzina la matenda. Woyamba kudziwika kwa tsiku, ikulongosola za matenda anapereka dokotala Greek Saranus. matenda Izi zowawa Chimakedoniya, Newton ndi ena ambiri odziwika kanjedza mbiri.

Chiwerengero cha anthu amene amapezeka zizindikiro gout chaka chilichonse kumawonjezera. M'malo mwake, akhoza zimachitika abwino a moyo ndi mphamvu. M'pake kuti matenda umatchedwanso "matenda a olemekezeka."

Vuto la matenda ndi mochedwa matenda ake, kawirikawiri kale mu gawo aakulu, pamene ndondomeko matenda si zimfundo nawo.

Zizindikiro zoyambirira za gout zambiri zimayamba kusokoneza amuna a usinkhu wapakati. Koma matenda ndi zambiri "mphamvu" posachedwapa. Angapezeke anthu makumi atatu achinyamata. Kwa ambiri a kupempha thandizo gout kuukira limayamba ndi maonekedwe a ululu ndi kutupa choyamba (wamkulu) chala. Ichi ndi tingachipeze powerenga Baibulo. Enawo amalembedwa ululu molumikiza ena phazi, komanso mfundo zikuluzikulu za nthambi.

Kumvetsa pathogenesis ya matenda, muyenera kukhala ndi kumvetsa kagayidwe yachibadwa asidi uric. Anthu, ndi chifukwa cha akuwaza wa purines. Magwero wathu chamoyo n'kupanga zidulo amenewa ankadya zakudya kukhudzana zomwe zili purines (nyama, nyemba, vinyo wofiira, nsomba, etc.), maselo Nucleoproteins. Excreted asidi uric ndi linanena bungwe mwa intestine m'mimba zomera matumbo, ndi mkodzo (mbali yaikulu).

Zimayambitsa matenda

Amadziwika kuti pali zizindikiro za gout ndi kaphatikizidwe ndi muyeso wa asidi uric mu thupi ndi kuchepetsa excretion ake mu mkodzo. Kuwonjezeka mapangidwe asidi mwina chifukwa mowa kwambiri zakudya munali purines ndi apamwamba, kaphatikizidwe lamkati la purines mu thupi.

Kuonetsetsa chachikulu ndi hyperuricemia sekondale. Gout chifukwa cha chimake choyamba. Secondary kuchuluka kwa asidi uric magazi nthawi zambiri chifukwa cha kulephera aimpso, myeloma angapo, ena mitundu ya khansa ndi magazi m'thupi, ndi kumaonekeranso mu ntchito pokonzekera zachipatala, mwachitsanzo, okodzetsa.

An owonjezera asidi magazi kumabweretsa mafunsidwe ake ziwalo ndipo zimakhala. Mu mawonekedwe a urate ndi sodium uyikidwa ku bursa ndi likulowerera mu madzimadzi synovial. Urata kudutsa mu chichereŵechereŵe, ndi kuchititsa kutupa ndi kuononga.

zizindikiro za gout

Monga taonera, Baibulo tingachipeze powerenga ndi matenda anzake a pachala chachikulu. Palokha, ndi muyeso wa asidi uric mu thupi alibe chifukwa zizindikiro zilizonse, ndipo imatiuza za kugonjetsedwa kwa olowa imeneyi. Nthawi zambiri mliri amayamba ndi kudya, hypothermia, zoopsa kapena matenda. Nthawi zambiri nyamakazi kuukira amapezeka ndi maziko a wathunthu bwino, ngakhale zina amalembedwa zizindikiro precursors monga kusintha kawirikawiri maganizo, amaika irritability, etc.

Kawirikawiri ululu kuoneka usiku ndipo mwadzidzidzi. ululu kwambiri ndipo zimenezi n'zosatheka kukhudza olowa. Pa nthawi yomweyo pali kutupa ndi redness. Pambuyo limodzi kapena masiku awiri, ululu anabauka. Mbali khalidwe la ululu nyamakazi zake mwadzidzidzi mwadzidzidzi chiyambi ndi mapeto mwadzidzidzi. Ngati mfundo yaikulu amakhudzidwa, chithunzi matenda ndi amatikumbutsa phlegmon. Zimfundo akhoza kupangidwa tophi. Iwo tokhala kutayidwa pansi pa khungu kapena mafupa (urate madipoziti). Kuchuluka okwera magazi asidi uric.

chithandizo

Kumuukira pachimake ntchito colchicine, odana ndi yotupa, mankhwala analgesic (NSAIDs). Nkofunikira kuti zakudya ndi kupatulapo zakudya byproducts nyama, mowa.

Chinthu chachiwiri ndi kuika mankhwala kuchepetsa kupanga thupi asidi uric. Motero mankhwala ndi allopurinol kapena analogs ake. Izi mankhwala ntchito mankhwala mosalekeza ndi yaitali ..