Zizindikiro kugwirizana ndi hemolytic-uremic syndrome ndi mankhwala ake

Choncho, kodi muyenera kudziwa woyamba wa zonse chifukwa hemolytic-uremic syndrome (chidule - Hus). Madokotala amanena matenda makamaka ndi zizindikiro zitatu: pachimake aimpso kulephera, hemolytic magazi m'thupi, thrombocytopenia. Tikumbukenso kuti mbali yotsirizira nthawi akuwonetseredwa bwino kwambiri. Matendawa matenda makamaka ana.

zingayambitse

zinthu zazikulu zimene imakhudzana ndi matenda hemolytic-uremic - ndi matupi awo sagwirizana anachita mankhwala, komanso matenda a tizilombo. M'pake kuti matenda wayamba kukhala pambuyo matenda pachimake kupuma ndi m'mimba kapena odwala kulandira mankhwala. Pankhani ya pathogenesis wa Hus, chikutanthauza Chofunika kwambiri ndi Ufumuyo pamaso pa zochita autoimmune. Nthawi zina, akhoza kungadzutse zokhudza zonse microangiopathy.

symptomatology

Kodi zizindikiro zambiri chifukwa cha hemolytic syndrome uremic? Tikumbukenso kuti njira ya matenda ndi madokotala conventionally kugawidwa m'mbali zitatu. Choyamba, prodromal, ukhoza kuyambira tsiku lina kwa masabata awiri. Chachiwiri, otchedwa "mavuto nthawi" - milungu wina ndi atatu. Kenako pakubwera nthawi kuchira (kapena imfa) wodwala.

Mbali yoyamba ya matenda wonse akufanana poyizoni ndi limodzi mwa zizindikiro monga kusanza, kupweteka m'mimba, matenda otsekula m'mimba ndi kuda magazi. Odwala ena mu gawo ili amalembedwa khunyu, kusinza ngakhale imfa ya chikumbumtima. Patapita nthawi prodromal odwala ambiri mukubwera kuchira kuwoneka. Ndi haemolytic uraemic syndrome kugwirizana akatswiri monga kuchepa magazi haemolytic, thrombocytopenia, ndi zotupa aimpso. Madokotala amanena kuti chithunzi matenda, monga ulamuliro, kusiyana ndi polymorphism a. Odwala ena, zizindikiro, zikhoza kusokoneza hemolytic mavuto, ena - zizindikiro za pachimake kulephera aimpso. Common milandu ankaona chizindikiro cha magazi m'thupi hemolytic - zikuoneka mkati mwa Hus.

syndrome Hemolytic-uremic ana mu gawo lachiwiri amakhala ndi pallor imfa ya pakhungu. Pamaso pa matenda a chikasu ndiyo angathe kuonedwa hyperbilirubinemia. Direct Coombs 'kuyesedwa ndi zambiri zoipa, polowetsedwa hemoglobin, chiwerengero cha erythrocytes yafupika. Komanso, odwala zambiri mphuno magazi.

diagnostics

Madokotala zambiri oterewa Hus, potengera muyezo waukulu atatu: kukhalapo kwa magazi m'thupi hemolytic, thrombocytopenia purpura ndi uremia. Nthawi zambiri, chithunzi matenda ndi amatikumbutsa syndrome Moshkovitsa (matenda a impso, magazi kuundana zida, ndi zina zotero. D.), ndi kusiyana kokha kukhala kuti yotsirizira zambiri ena mwa ana okulirapo, ndi mikrotrombozov kumachitika makamaka mtima ndi chiwindi.

Hemolytic uremic syndrome: chithandizo

Yimitsira autoaggression - ndicho cholinga chachikulu cha mankhwala. Monga ulamuliro, madokotala anatumiza magulu onse kuti kuteteza intravascular coagulation. Bwino kuthandiza heparin ndi prednisolone. Ngati mankhwala si kuthandiza, imasonyezedwa hemodialysis.