"Ademethionine": malangizo ntchito, analogs, ndemanga

Kodi mankhwala ademetionine? Malangizo ntchito lokonzekera, munali chigawo chimodzi kuti adzakhala anafotokoza hereinafter. Ifenso kukuuzani mmene ndalama chida ofanana chomwe anthu akunena za izo, ndi zina zotero.

Mtundu wa mankhwala, malongosoledwe ake

Mu mawonekedwe zimene zilipo mankhwala "Geptral" (alendo "Ademethionine")? Malangizo Ntchito limanena kuti chida ichi likupezeka mu njira ziwiri zosiyana:

• The lyophilizate, anafuna kuti yokonza njira mtsempha kapena mu mnofu. fomu iyi ndi misa lyophilized woyera, popanda inclusions yachilendo. Komanso, mu makatoni mtolo lili zosungunulira wapadera amene ali ndi maonekedwe a madzi colorless ndi poyela.
• "Ademethionine" - mapiritsi mu woyera envelopu, biconvex ndi chowulungika. Komanso homonymous yogwira mankhwala, izi zikutanthauza limapangidwa ndi zinthu wothandiza monga MSC, Na-carboxymethyl silika ndi stearate mg.

makhalidwe pharmacodynamic

Kodi katundu wa ademetionine mankhwala? Ntchito malangizo imafotokoza kuti anati pophika zinaonetsedwa pa chionetserocho choleretic, holekineticheskoe, detoxifying, neuro- ndi hepatoprotective ndi odana ndi nkhawa ndi mavuto antioxidant.

Choncho tikhoza kuona kuti ankaona mankhwala mchitidwe angathe utithandize katulutsidwe wa ya ndulu, ndipo imautsa kulekana ake mu intestine lapansi.

Komanso dziwani kuti mankhwala "Ademethionine" analogs amene ali pansipa, amadzaza kuchepa Sam, komanso kumapangitsa mapangidwe mu chiwindi. Ndiponso, izi zikutanthauza bwino kumawonjezera plasma ndende ya cysteine, taurine, glutamine zili mu chiwindi, motero normalizing njira kagayidwe kachakudya mu chiwindi ndi kuchepetsa mlingo wa methionine ku seramu.

M'mikhalidwe amatanthauza "Ademethionine" mwaluso kwambiri? Malangizo ntchito akusonyeza kuti mankhwala uyu akuchita bwino ndi ductal ndi tubular kwa chiwindi cholestasis. Iwo amachita conjugation LCD ndi sulfation maselo a chiwindi, kenako Sachita kawopsedwe awo.

Malinga ndi malipoti a akatswiri, choleretic ndi hepatoprotective zotsatira pambuyo discontinuation mankhwala "Geptralom" kusungidwa kwa miyezi 3.

Pamene kugawa izi zikutanthauza anthu ndi zizolowezi opioid, kenako matenda a chiwindi bwino ili ntchito chiwalo monooxygenase njira makutidwe ndi okosijeni, komanso kumathandiza kuti mgwirizano zizindikiro matenda a achire mankhwala.

Antidepressant zotsatira pambuyo ntchito mankhwala akufotokozera pang'onopang'ono. Komabe, iye ziziyenda m'sabata ziwiri zapitazi.

amatanthauza mphamvu ya kayendedwe ndi

kuchiritsidwa "Ademethionine" odzipereka? Malangizo ntchito malipoti kuti pakamwa bioavailability ake ndi 5%, ndipo pamene ntchito jekeseni - 100%.

Pachimake ndende ya mankhwala mu magazi pa mlingo umodzi wa piritsi limodzi zimawonedwa kwa maola 2-6.

The plasma mapuloteni-womangidwa boma la wothandizila ichi ndi zedi yaing'ono. Iwo ayenera kukumbukira kuti mankhwala likulowerera bwino mu BBB, ndi woipa mkulu mosavuta wapezeka ngakhale mu madzimadzi cerebrospinal.

Biotransformation mankhwala akuwululidwa mu chiwindi. Kupha ake theka nthawi maola 1.5. Linachokera mankhwala impso.

Zikuonetsa kuti zoti njira

N'chifukwa chiyani tiyenera kuchiritsidwa "Ademethionine" (mtengo wa mankhwala mwachindunji m'munsimu)? mankhwala Izi kawirikawiri analamula kuti:

• zizindikiro za maganizo;
• intrahepatic cholestasis ndi pa limati cirrhotic pretsirroticheskih, kuphatikizapo steatosis kwa chiwindi;
• aakulu cholecystitis popanda miyala;
• aakulu a chiwindi;
• cholangitis;
• poizoni kwa chiwindi zotupa chiyambi osiyana, kuphatikizapo tizilombo mowa, ndi mankhwala (tricyclic antidepressants, mankhwala antivirals, antitumor ndi odana ndi TB mankhwala, m'kamwa kulera);
• matenda enaake;
• intrahepatic cholestasis mu amayi apakati;
• encephalopathy, kuphatikizapo kugwirizana ndi kwa chiwindi insufficiency (mowa).

Ziletso ntchito

Kodi zinthu sayenera mankhwala mankhwala "Ademethionine" kapena "Geptral"? Izi zikutanthauza ntchito matenda majini okhudza methionine adzizungulira, komanso kuchititsa hyperhomocysteinemia kapena homocystinuria. Kwalembedwa contraindicated kulandira ubwana ndi unyamata ndi mkulu kudziwa ademetionina.

N'zimene "Ademethionine" Mapale

Mlendo akatswiri amanena kuti amachita ndi njira kumwedwa pakati chakudya m'mawa, osati onongani kapena kutafuna. Pankhaniyi, phale chiyenera kuchotsedwa mu ma CD mwachindunji musanayambe kumwa.

Mlingo tsiku la mankhwala ndi miyala 2-4, ndi nthawi ya mankhwala zimadalira umboni umene ulipo.

Malangizo ntchito njira

Kodi ndimagwiritsa ntchito injectable njira "Ademethionine" analogues amene angapezeke mu ogulitsa mankhawala iliyonse? Zinthu zimenezi amagulitsidwa ampoules, intramuscularly kapena kudzera m'mitsempha. Choncho mtsempha jekeseni ikuchitika pang'onopang'ono.

The njira mankhwala zakonzedwa kusanachitike jekeseni ndi ntchito ufa lyophilized kwa dilution zosungunulira kuti ali mu phukusi makatoni.

Pambuyo jekeseni wa mankhwala ayenera kuwataya.

Tikumbukenso kuti injectable mawonekedwe "ademethionine" atakwatirana ndi njira zamchere ndi formulations munali Ca ayoni.

Mlingo tsiku la wothandizila kwa TOLC 1-2 ampoules. Mankhwalawa medicament izi kumatenga masabata awiri.

Pamene maganizo mankhwala ankaona ntchito mlingo wofanana. Pamene jekeseni imeneyi ikuchitika masiku 15-18.

Ngati wodwalayo amafuna mankhwala wothandiza, ndiye unasamutsidwira piritsi mawonekedwe "Heptral".

zotsatira zoyipazi

zochita zoipa zingachititse mankhwala "Ademethionine" (400 mg) Nthawi zambiri pa mankhwala ndi mankhwala odwala ndi kutsekula m'mimba, kupweteka m'mimba ndi nseru.

Nthawi zina kugwiritsa ntchito "Geptral" njira, komanso mawonekedwe ake piritsi angachititse chitukuko:

• Ndondocha (i.e. mkodzo thirakiti matenda);
• laryngeal edema, zochita hypersensitivity;
• paresthesia, nkhawa, kupweteka kwa mutu, kusowa tulo, chizungulire, kusokonezeka;
• kuyabwa, mawonetseredwe khungu la chifuwa, totupa, angioedema, thukuta;
• kutupa makoma a mitsempha chabe, matenda a zotengera mtima ndi magazi, otentha cheza;
• bloating, pakamwa youma, kusanza, esophagitis, nseru, kupweteka m'mimba, kutsekula m'mimba, dyspepsia, matenda zinchito pa mundawo m'mimba, bloating, biliary colic, chiwindi matenda enaake, magazi kuchokera thirakiti zosiyanasiyana GI;
• olowa ululu, minofu kuphipha;
• malaise, fuluwenza, monga matenda, malungo, kuzizira, edema zotumphukira, asthenia.

Mtengo wa mankhwala, analogs ndi ndemanga

Zingati mankhwala monga "Ademethionine"? Mtengo wa mankhwala ndi pafupifupi 1,500 rubles pa mawonekedwe piritsi ndi za 1900 rubles pa jekeseni.

malipoti medicament akhoza m'malo ngati n'koyenera kudzera monga "asidi Glutamic" "Karnith" "Histidine" "carnitine", "Epilapton", "Elkar".

Zimene anthu amanena za ogwiritsa ntchito mankhwala? Malinga ndi malipoti a odwala amene aona chiwindi matenda mankhwala "Ademethionine" ndi chenicheni chokhacho ntchito gepatoprotektor. Odwala ndi matenda a "matenda enaake" amanena kuti bwino chithandizo chingapezeke pokhapokha ngati mankhwala yogwira anatengedwa nthawi 2 chaka 3-mwezi maphunziro.

Koma madokotala, iwo amanena kuti mankhwala "Ademethionine" Kodi kupereka kutchulidwa ndi mofulumira anachita matenda yotupa chiwindi, kenako stagnation wa ya ndulu mu zimakhala za thupi.