AFP pa mimba. mayeso AFP

Alpha-fetoprotein (AFP) - yoopsa mapuloteni reproducible chiwindi ndi ziwalo m'mimba mwa mwana wosabadwayo, amene ali bwinobwino pano mu magazi ndi amniotic madzimadzi za amayi apakati. Mkulu kapena otsika kuchuluka kwa AFP likhoza kulumikizidwa ndi zilema zina kubadwa, monga Edwards matenda, matenda Down, anencephaly, wolumala msana ndi zina zotero. Kuti zolakwika n'zotheka chitukuko cha mwana wosabadwayo udzayesera AFP.

Kodi AFP mayeso?

Mu nthawi ya kuyambira pa 15 kwa sabata la 20 mimba, akazi ambiri pakati analimbikitsa kuchita olanda matenda akalandire chithandizo, nthawi zambiri amawapatsa mantha. Imodzi mwa njira kwambiri chosaopsa kuti sitingafunikire kutero ndi malowedwe mkati, ndi AFP mayeso, amene ndiyo AFP pa mimba mwa magazi a mayi. Tengani magazi kuchokera mu mitsempha ya amayi ndi kutumizidwa ku zasayansi kwa kusanthula. Zotsatira zake n'zakuti, monga ulamuliro, amadziwika pambuyo masabata 1-2, akuwafanizira ndi zaka mayi ndi maziko ake mitundu, kupenda mosavuta matenda angathe chibadwa.

Zizindikiro zolondola kwambiri mayeso izi zimapereka 16 18 pasabata. Chifukwa chakuti AFP pa mimba kumasintha mlingo wake ndende kwa zotsatira chodalirika kafukufuku umafuna tsiku lenileni mimba. Komabe, tiyenera kukumbukira kuti zotsatira si matenda, koma zimasonyeza kuti amafuna diagnostics zina kudziwa malformations kobadwa nako mu mwana wosabadwayo.

Amene analimbikitsa AFP mayeso?

Kumene, ndi zofunika kuti amayi apakati amene anachita kafukufuku ofanana. Komabe, mu AFP kuvomerezedwa pa mimba muyenera kuyesetsa akazi:

• ndi mbiri banja ndi vuto lobadwa;
• wamkulu kuposa zaka 35;
• ankamwa mankhwala osiyanasiyana kapena mankhwala pa mimba;
• ndi matenda a shuga.

Ngati AFP ndi kukwezeka, kungasonyeze kuti mwana wosabadwa ali ndi ubongo chubu chilema monga wolumala msana kapena anencephaly, impso ndi kuvutika thirakiti mkodzo ndi zilema zina kubadwa. The mkulu mlingo wa AFP amathanso amati olumala esophageal. Komabe, chifukwa ambiri a misinkhu okwera AFP ndi zolakwika chibwenzi mimba.

Ngati AFP pa mimba ndi anachepetsa ndipo pali nthenda kaperekedwe ka hCG ndi estriol, izi zingasonyeze kuti mwana wosabadwayo osauka mwina kukula retardation, trisomy 18 (Edwards syndrome), trisomy 21 (ozerezeka) kapena zina kuvutika chromosomal.

Zotsatira AFP kuyezetsa

Nkofunika kukumbukira kuti AFP mayeso - si mayeso matenda yekha limanena kuti thanzi la mwana wosabadwayo ali pangozi. Pankhani ya milingo nthenda ya alpha-fetoprotein amafuna kuyezetsa zina matenda zolondola. Njira zambiri ndiwofatsa ndi kukachititsa yachiwiri AFP mayeso kapena 3D-ultrasound. Ngati retesting imasonyeza kuti AFP pa mimba (yachibadwa AFP masamu ngati ntchito ya zaka gestational) anakokomeza kapena understated amawatumiza njira zambiri olanda monga amniocentesis.

Ngakhale kuti chiyesedwe alpha-fetoprotein si ikuchitika kwa amayi apakati, zina m'pofunika. Komanso, kuwonjezera pa kusapeza oitana magazi, palibe ngozi kapena mavuto kugwirizana ndi kukhazikitsa. Ichi ndi mayeso mwachizolowezi kuti si amakhudzana ndi malowedwe mkati, ndi Choncho musadzitame angabweretse chiopsezo kwa mayi komanso mwana. Ngati mayeso si nsembe, mkazi yekha akhoza kunena pa kumalo ake (kupatula, ndithudi, ankakhulupirira kuti akanatha pamodzi ndi mwana wake), kuonetsetsa njira yachibadwa mimba.