Kuthamanga oncotic

Tinabadwa oncotic kuthamanga (ili osmotic yomweyo) - mankhwala kuti kupasuka zinthu zimene anapanga magazi ndi madzi a m'magazi. Ndi kuchepa kwa mapuloteni mu thupi utachepa, kungachititse chakuti chifukwa kudzikundikira edema madzimadzi adzayamba kuonekera. Ichi ndi chifukwa chakuti Kakhungu chotengera m'makoma translucent ndipo semipermeable. Iwo bwino ndi momasuka pochitika madzi, pamene ayoni ndi mamolekyulu zinthu zosiyana - poipa.

Normal oncotic kuthamanga ndi za 7.5 ATM. (5700 mamilimita Hg kapena caka ca 762 kPa). Ntchitoyi zimasiyanasiyana mu plasma dera 290 mOsm / l.

Komabe, osmotic kuthamanga chimaonekera osati mwa kuchuluka kwa mamolekyulu kotero, ngati maganizo awo. Ambiri mwa ayoni plasma (za 99,5%) ndi ayoni zochita kupanga, anthu ambiri potsata kuthamanga oncotic. Mavuto mapuloteni plasma ndi mbali yaing'ono ya onse ATM 0.03-0.04. (25-30 mamilimita Hg). Koma M'pofunikanso kukumbukira kuti mavuto ndi mapulotini n'chofunikira zovuta kufalitsa madzi pakati pa plasma ndi zimakhala zazikulu.

Mbali imeneyi ya ndondomeko ndi kuganizira chizindikiritso cha kuthamanga oncotic. sachita kapepala madzi zikutanthauzanji kuti mpanda wa capillaries makamaka kuwoloka mapulotini. The interstitial madzimadzi mapuloteni laling'ono kwambiri, choncho maganizo awo masinthidwe amtundu analandira mbali zonse za capillary ndi.

Chifukwa mkulu oncotic mavuto madzimadzi danga intercellular si kudziunjikira, ndipo zikamamvekamveka.

Pakuti kupewa kuthamanga oncotic yovomereza chithandizo cha preeclampsia, ndilo ndithu yaikulu kotero kuti zotsatira sizitenga nthawi yaitali. Ndi wabwinobwino magazi clotting mapuloteni matenda izo, kulola kuti kuchepetsa kufala kwa matenda a mtima.

Oncotic magazi nthawi anali pa mlingo zonse. Kwa lamulo neurohumoral nawo ziwalo excretory monga zopangitsa thukuta , ndi impso. Kucepesa kapena kuonjezera kuthamanga oncotic anazindikira pa periphery makoma chotengera ndi gawo chapakati (a ubongo imene imalamulira kutentha) komwe antidiuretic timadzi adzamasulidwa imagwira mayamwidwe njira mitsinje impso. Ntchito yake zonse mkodzo mapangidwe ndondomeko. Mtendere wa kuthamanga osmotic kupereka ADN, aldosterone, parathormone, urenichesky mtima timadzi.

Ndi reflex amapezeka Kupeleka ziwalo kusintha zinthu kapena chifukwa mu kuchedwa kwambiri, kapena imfa yadzidzidzi ya madzimadzi ndi mchere m'thupi. Mu njira imeneyi, woyamba ndi udindo lalikulu amapita mapuloteni (oncotic kuthamanga) okhoza kumumanga ndi kumasulidwa ayoni. Mu zinthu excreting ziwalo (impso ndi zopangitsa thukuta), mankhwala kagayidwe kachakudya, amene mosalekeza aumbike mwa thupi, ambiri a iwo alibe kungasokoneze kuthamanga osmotic.

Matenda oncotic kuthamanga mlingo imakhudzana ndi vutoli chiweruzo mapuloteni albumins plasma ndi globulins, anions, cations, sodium, potaziyamu, calcium ndi mbali zina. Izi choncho chifukwa zinthu zosiyanasiyana pathological ndi matenda (kuledzera, zilonda zamoto, nthawi pambuyo kugwira ntchito, mantha, kukha mwazi matenda osiyanasiyana, ndi zina zotero). Zikatero, onani kuthamanga oncotic n'chofunika kwambiri nthawi zonse. Chithandizocho kwenikweni pa kuchotsa matenda chimapangitsa ndi kukonzanso bwino salt mu madzi a m'magazi magazi. Komabe, pamaso mumasamalira kuthamanga, makamaka oncotic, onetsetsani kukaonana ndi dokotala. Kodi musalankhule medicate!