Mannit. Malangizo ogwiritsidwa ntchito

Mankhwala "Mannit", amene mtengo wawo uli pafupifupi makoswe 90, ndi gulu la mankhwala odzola. Kukonzekera kumakhala ngati njira yothetsera matenda opatsirana. Mankhwalawa ndi mannitol. Wothandizira amathandizira kuwonjezera mphamvu ya osmotic mu plasma. Mankhwalawa amachititsa kuti madzi asungidwe komanso kuchuluka kwa mkodzo. Mankhwalawa sangathe kudutsa muzitsulo za minofu ndi ma selo, sizingawonjezere nayitrogeni. Wothandizira "Mannit" (malangizo ogwiritsira ntchito ali ndi deta) amadziwika ndi kusakayika bwino, choncho amalowa mkati mwawo. Pali pang'ono kagayidwe kabakiteriya pachiwindi. Mankhwalawa amatulutsidwa mu mkodzo.

Zisonyezo

Mankhwalawa amatchedwa "Mannitol" omwe amalembedwa kuti azikhala ndi ubongo, osagwira ntchito molakwika (motsutsana ndi vuto lopweteka kwambiri kapena losabadwa). Mankhwalawa amagwiritsidwa ntchito posokoneza matenda a posttransfusion pokhudzana ndi kukhazikitsa magazi osagwirizana, diuresis (kukakamizidwa) kutsogolo kwa salicylate poisoning, barbiturates. Mankhwala a "Mannit" omwe amagwiritsidwa ntchito amagwiritsira ntchito amalangizi a oliguria chifukwa cha kupweteka kwamtambo kapena kupweteka kwa mphuno kumathamangitsidwa ndi ziwalo zogwirira ntchito. Mankhwalawa amalembedwa pofuna kupewa hemolysis mu ntchito pogwiritsa ntchito mitundu yosiyanasiyana kuti asagwiritsidwe ntchito ndi ischemia mu impso komanso kuthekera kovuta kwa njira ya chiwindi.

Contraindications

"Mannitol" (maulosi othandizira amavomereza izi) saloledwa kuti agwiritsidwe ntchito mu anuria akuphatikizana ndi chifuwa chachikulu chotchedwa renal tubular necrosis, hypersensitivity, kulephera kwa ventricular (makamaka ndi pulmonary edema). Mankhwalawa sakuvomerezeka chifukwa cha kuchepa kwa magazi (kuphatikizapo kutaya mwazi pa nthawi ya chigaza), kupweteka kwa magazi, kutaya thupi kwambiri, hypokalemia. Contraindications zikuphatikizapo hypochloraemia, hyponatremia. Chenjezo pamene olemba achikulire amawafotokozera. Kugwiritsa ntchito mankhwalawa panthawi yomwe ali ndi mimba kapena nthawi ya lactation kumakhazikitsidwa ndi katswiri.

Mankhwala "Mannit." Malangizo ogwiritsidwa ntchito

Mankhwala osakaniza kapena struyno mankhwala amayamba pang'onopang'ono. Kwa njira yokonza yokonza kusankha mankhwala mu mlingo wa 0,5 g / kg kulemera, mankhwala - 1-1.5 g / makilogalamu. Pa tsiku lomwe mankhwalawa sayenera kukhala oposa 140-180 g. Asanayambe kulowetsedwa, mankhwala a "Mannit" amalimbikitsa kuti malangizo oti agwiritsidwe ntchito ayambe kutenthedwa ndi kutentha madigiri 37. Pazigawo zomwe zimagwiritsidwa ntchito pogwiritsa ntchito mankhwalawa, mankhwalawa amagwiritsidwa ntchito pa mlingo wa 20-40 g. Odwala oliguria amapatsidwa mlingo woyambira 200 mg / kg kwa mphindi zitatu kapena zisanu. Ngati palibe kuwonjezeka kwa liwiro la diuresis mkati mwa maola awiri mpaka 30 mpaka 50 ml / h kuchokera kwa kayendetsedwe ka mankhwala, m'pofunika kukana.

Mankhwala "Mannit." Malangizo ogwiritsidwa ntchito. Zotsatira zoyipa

Chifukwa cha kugwiritsa ntchito mankhwala, kuchepa kwa madzi m'thupi, kuchepetsa kupanikizika, matenda m'thupi-electrolyte metabolism, kufooka kwa minofu, dyspepsia amadziwika.