"Moxonidine": malangizo ntchito kwenikweni

ndiwo mankhwala "Moxonidine" n'chiyani? Malangizo ntchito chida ichi, amakambirana za izo, contraindications, ndi analogs zafotokozedwa mwatsatanetsatane m'nkhani ino. Komanso, tidzakhala kukuuzani njira zimene tiganizire cholinga, ngati iye ali zovuta zilizonse ndi mawonekedwe mu umene inakhazikitsa.

The mawonekedwe ndi zikuchokera mankhwala

kugulira mankhwala "Moxonidine" ndi thupi lotani? Izi mankhwala anagulitsa kokha mu mawonekedwe a mapiritsi. mchitidwe awo yogwira ndi mankhwala monga moxonidine. Pankhani zigawo zina zokhudza thereto mapadi microcrystalline, Kasitolo mafuta, Aerosil A-380, hydroxypropylcellulose, magnesium stearate ndi Tween 80.

Mapiritsi amagulitsidwa phukusi makatoni. phukusi wina akhoza kukhala ndi 98, 60, 56, 42, 40, 30, 28, 20, 14 ndi miyala 10.

The pharmacological katundu wa mankhwala

N'chifukwa chiyani ndikufunika mankhwala "Moxonidine"? Malangizo ntchito limanena kuti kukonzekera ichi ndi antihypertensive mankhwala. njira yake ya kanthu kwagona kuti yogwira mankhwala njira amakhudza limasonyeza lalikulu lamulo magazi. M'mawu ena, moxonidine - imidazoline cholandilira agonist ndi (makamaka).

Mankhwala kumabwezera mmbuyo ntchito za pakati vasomotor, kuchepetsa ukutsika zotsatira wachifundo pa dongosolo mtima. Kuthamanga (diastolic ndi systolic) amachepetsa pang'onopang'ono.

medicament kuonedwa ndi ife ndi osiyana ndi atumiki antihypertensive sympatholytic chakuti ali yekha kuyandikana yaing'ono kwa alpha-2-adrenoretseptoramm. Ikufotokoza Mwina otsika a pakamwa youma ndi sedation.

Sitingathe kunena kuti moxonidine angadwale insulin tilinazo index (pafupifupi 21 peresenti) anthu ndi kunenepa.

Pharmacokinetics mankhwala

Kodi mankhwala imatsala, "Moxonidine"? Ogwiritsa ntchito limati atalandira medicament yomweyo ndipo pafupifupi kuganizira thirakiti chapamwamba m'mimba.

Bioavailability (mtheradi) cha chida peresenti 88. Ndende pazipita zimatheka pambuyo Mphindi makumi asanu asanu. Pankhaniyi, kumwa chakudya ndi zopanda phindu pa pharmacokinetics wa amafotokozera achangu ayi.

Kulankhulana ndi mapuloteni magazi za 7.3%. The metabolite yaikulu ya Moxonidine Moxonidine amachita limafooka, ndi guanidine ofanana nawo.

Hafu ya moyo wa moxonidine ndi metabolites ake anali 150 ndi 300 mphindi motero.

Pambuyo ingestion kwa maora twente-foro mankhwala excreted ndi impso mu buku 90%. Komanso, chinthu yogwira akutuluka ndi kudzera intestine lapansi.

Zikuonetsa ntchito chipangizo zachipatala

Nthawi zina, prescribers 'Moxonidine "? Kugwiritsa ntchito mankhwala asonyeza kokha ngati kudwala monga matenda oopsa wolumikizira.

Contraindications ntchito chipangizo zachipatala

Nthawi zina, madokotala si mankhwala odwala awo 'Moxonidine "? Malangizo ntchito mankhwala lili si mndandanda kwambiri contraindications. Muchiyese tsopano.

Choncho contraindications kugwiritsa ntchito "Moxonidine" kukonzekera ndi zinthu zotsatirazi:

• anasonyeza AV-chipika 2 ndi madigiri 3, SSS;
• bradycardia (zosakwana 50 kumenyedwa pamphindi);
• achinyamata ndiponso zaka ana (zaka 18);
• aakulu ndi pachimake kulephera mtima;
• mwana kudyetsa nthawi;
• Hypersensitivity kuti zinthu yogwira.

Mankhwala "Moxonidine": malangizo ntchito

Umboni za medicament izi Adzaperekedwa kumapeto kwa nkhani ino. Tsopano ine ndikufuna kuti ndikuuzeni inu za mmene kugwiritsa ntchito mankhwala bwino patsogolo pathu.

Mankhwala "Moxonidine" ali mkati yekha. Mlingo mu mankhwala oyambirira akhale 200 micrograms kamodzi patsiku. M'kupita kwa nthawi, inu mukhoza kutenga 400 micrograms.

Pamafunika kusintha munthu kuchuluka tsiku la mankhwala malingana tolerability wa mankhwala. Malinga ndi malangizo, mlingo pazipita medicament patsiku ndi 600 mg (ogaŵikana masitepe awiri).

Kwa odwala ndi insufficiency aimpso (zolimbitsa ndi aakulu), ndi anthu amene ali pa hemodialysis, mankhwala ndi kutumikiridwa mu kuchuluka kwa 200 mg tsiku lililonse. Ngati ndi kotheka (mopirira zabwino), mwachindunji mlingo akhoza ziwonjezeke kwa pazipita (i.e. 400 mg).

mavuto atalandira medicament

Kodi mavuto a mankhwala "Moxonidine"? Umboni za iye kuti nthawi zina mankhwala kumachititsa ndi kuwonongeka wa thanzi. Taonani mndandanda wa zotsatira zoyipa lili malangizo:

• Mantha dongosolo (chapakati): mutu, kukomoka, chizungulire, ndi somnolence.
• M'mimba thirakiti: kusanza, youma pakamwa, kutsekula m'mimba, dyspepsia ndiponso nseru.
• dongosolo mtima: bradycardia, amalembedwa akuponya magazi, orthostatic hypotension.
• Khungu ndi subcutaneous minofu matenda: angioneurotic edema, pruritus ndi ziwengo.
• matenda Psychiatric: mantha ndi kusowa tulo.
• Kukhotakhota matenda a limba Makutu: akamaganizira za (zimachitika kawirikawiri).
• System minofu ndi mafupa: ululu kumbuyo, kupweteka khosi.
• Zotsatira zoyipazi Common: zotumphukira edema ndi asthenia.

Monga mukuonera, "Moxonidine" mankhwala zingachititse kuwonongeka kwa alili. Ngati mavuto amanenedwa, ndiye mlingo wa mankhwala ayenera anasiya.

njira mogwirizana ndi mankhwala ena

Mankhwala "Moxonidine", "Moxonidine Sandoz" ndi analogues zina mankhwala anathandiza wodwala ndipo sanali chifukwa mavuto ena, iwo ayenera kumwedwa yekha mankhwala. Pambuyo phwando munthawi yomweyo chida ndi mankhwala ena angachititse zochita osafunika. Kodi kwenikweni, tiona tsopano.

Kamodzi ntchito mankhwala "moxonidine" ndi wothandizila chomwecho antihypertensive zingachititse zimakhudzanso zowonjezera.

Antidepressants (tricyclics) kuchepetsa dzuwa la mankhwala antihypertensive kanthu chapakati. Pa nkhani imeneyi, iwo ali osavomerezeka ntchito molumikizana ndi zinthu monga moxonidine.

Ankaona oyandikana medicament mosavuta zimawonjezera zotsatira za mankhwala, tricyclic antidepressants, komanso Mowa, hypnotics ndi mankhwala.

Thunthu yogwira ndi medicament amtengo attenuated bwino ntchito chidziwitso anthu amene imodzi kulandira lorazepam.

Ngakhale poika "Moxonidine" mankhwala ndi "benzodiazepine" Mwina kwambiri sedation opangidwa kuchokera kwa masika.

Akatswiri amanena kuti Moxonidine analandira mwa katulutsidwe tubular. Mogwirizana ndi zimenezi siziyenera kugwiritsidwa ntchito ndi mankhwala amene katswiri ndi katulutsidwe tubular.

Nthawi ya gestation ndi mkaka wa m'mawere (mimba ndi mkaka wa m'mawere)

Kodi nthawi gestation kumwa mankhwala "Moxonidine-LF"? Malangizo mankhwala lili ndi mfundo imene mosamalitsa kulamulidwa ndi maphunziro okwanira za chitetezo cha mankhwala ankaona pa mimba kunachitidwa. N'chifukwa chake ali osavomerezeka ntchito gulu la odwala.

Sitingathe kunena kuti mankhwala "Moxonidine" sayenera kugwiritsidwa ntchito pa yoyamwitsa. Ichi ndi chifukwa chakuti iwo yafotokozedwa ndi mkaka wam'mawere. Ngati pa mkaka wa m'mawere mankhwala koma aikidwa, ndiye kuyamwitsa ayenera anasiya.

Mu ndondomeko ya maphunziro (experimental) nyama, chinapezeka kuti medicament amakhudza embryotoxic.

malangizo enieni kugwiritsa ntchito mankhwala

Malinga ndi malangizo Ufumuyo, pamene ntchito mankhwala "Moxonidine" ayenera kusamala kwambiri ndi mosamala. Makamaka izo yokhudza gulu osiyana odwala. Chimene, ife kufotokoza tsopano.

kusamala makamaka pamene kutsatira "Moxonidine" medicament chakuti akuoneni odwala ndi digiri AV-anatseka misewu 1. Ichi ndi chifukwa chakuti anthu amenewa pali chiopsezo chachikulu cha bradycardia.

Komanso kulandira mankhwala iyenera kuchitikira kuyang'aniridwa ndi dokotala ndi aakulu inatsekeratu matenda mtsempha wamagazi, kulephera impso ndi wosakhazikika angina. Chimenechi ndi chifukwa chakuti zimene zinachitikira ntchito mankhwala ndi kuvutika ngati singakwane.

Ngati mukufuna kuletsa ntchito munthawi yomweyo mankhwala "moxonidine" ndi beta-blockers, muyenera choyamba adzafafaniza yomalizira, masiku angapo - wachiwiri.

Chibwenzi palibe umboni kuti atseka "Moxonidine" mankhwala kumabweretsa kuthamanga magazi. Komabe, ngakhale kuti akatswiri koma analimbikitsa gawo kunja mankhwala. mlingo ayenera kuchepetsedwa pa masabata awiri zapitazi.

ngati mankhwala kumakhudzanso kuthekera kuyendetsa galimoto zoyendera?

Pa nthawi ya mankhwala ndi "Moxonidine" anthu ayenera kusamala makamaka pochita chiswe, komanso pamene galimoto magalimoto. Ichi ndi chifukwa chakuti mankhwala akhoza kusokoneza phwando ndende ndi psychomotor zosiyanasiyana.

Analogs, ndipo mtengo wa mankhwala

Kugula mankhwala "Moxonidine" mu mankhwala popanda mankhwala. Mtengo wa mankhwala ndi wotsika. Per paketi, muli miyala 14 kulipira za 115-135 Russian rubles.

Ngati ife tiganizire mankhwala musalowe, kapena inu basi sanathe kupeza pa mankhwala, pambuyo kutumiza kwa katswiri, iwowa ayenera kukhala ndi khalidwe mankhwala analogue. Mwa mankhwala awa Ndikufuna kuunikila otsatirawa: "Fiziotenz", "Moxonidine-C3", "Moksarel", "Canon of Moxonidine", "Moksoniteks", "Moksogamma", "Tenzotran" ndi zina zotero.

Tengani ndalama ayenera mosamalitsa monga malangizo a dokotala a. Komanso, patsogolo ntchito mankhwala ayenera kukhala bwino ndi malangizo Ufumuyo.

Mankhwala "Moxonidine": ndemanga madokotala ndi odwala

Malinga ndi akatswiri, mankhwala othandiza kwambiri kwa matenda oopsa. maganizo amagawidwa ndi odwala. Komabe, ena a iwo anadandaula kuti pambuyo pakumwa mapiritsi a patapita kanthawi iwo asonyeze mavuto monga mutu, pakamwa youma, mantha ndiponso nseru. Pankhaniyi, madokotala amalangiza mankhwala kuletsa ndipo m'malo analogue ake, amene ndi otetezeka thanzi.