"Theophylline": malangizo ntchito, analogs

Kodi ndimagwiritsa ntchito mankhwala "theophylline"? Malangizo ntchito, analogs ndi makhalidwe a ndalama nkhani zotsatirazi.

Kapangidwe ndi mawonekedwe

Amenewa ndi mankhwala, "aminophylline"? Malangizo Ntchito limanena kuti chinthu yogwira chida ichi ndi dzina lomweli thunthu - aminophylline.

The mankhwala ndi akugulitsa monga njira yothetsera makonzedwe mtsempha, komanso mu mawonekedwe a mapiritsi, lotions kapena mafuta.

mbali pharmacological

ndi mankhwala monga "theophylline" n'chiyani? Malangizo ntchito (ampoules za mankhwala zikhoza kugulidwa ku malo ogulitsa mankhawala aliyense) akusimba kuti ndi vasodilating, antispasmodic, diuretic ndi bronchodilatory mankhwala.

Amafotokozera yogwira medicament ndi mchere wa theophylline ethylenediamine. Iwo ali bronchodilatory tingati ndi bronchodilator, chifukwa anasiya zotsatira zake mwachindunji pa mtima ulusi yosalala minofu ya m'mapapo ndi Airways. Amenewa chifukwa cha chopinga kusankha zochita phosphodiesterase, kuwatsogolera ndi kuwonjezeka mu msasa okhudza maselo ambiri.

katundu wa mankhwala

The chida chidwi "theophylline"? Malangizo ntchito limanena kuti akhoza kuchepetsa hyperreactivity pa mundawo kupuma. Limagwirira cha zimenezi akadali osadziwika, koma akatswiri amanena kuti ntchito mankhwala ankaona zimayambitsa kuchuluka ndi ntchito ya T-suppressors m'magazi.

Kuwonjezeka mucociliary chilolezo, kuwonjezera chidule cha chifundamtima, komanso zolimbikitsa ntchito intercostal minofu kupuma, chida imayendetsa pakati kupuma, kuthandiza kusintha tilinazo ake, ndipo umatithandiza alveolar mpweya wabwino, zomwe mapeto kuchepetsa multiplicity ndi kukula kwa nkhani apnea.

Monga zotsatira wina wa mankhwala, "aminophylline"? Malangizo ntchito (mafuta ndi njira ndi cholinga chofanana pa chamoyo) akusimba kuti pansi pa kuganizira zikutanthauza amazilamulira ntchito kupuma, potero kuwongolera magazi O2 machulukitsidwe ndondomeko ndi amachepetsa ndende ya mpweya. Komanso, yogwira mankhwala akhoza yotithandiza mpweya wabwino hypokalemia.

Tikumbukenso kuti "theophylline" malangizo ntchito imene pansipa, akuziyambitsa mtima, kumaonjezera pafupipafupi ndi mphamvu ya kugunda kwa mtima, kumawonjezera kufunika kwa minofu mtima mu O ₂ ndipo kwambiri kumawonjezera mtima magazi.

Kugwiritsa ameneŵa kumathandiza kuchepetsa oziziritsa mtima kamvekedwe, impso ndi khungu. Akatswiri amanena kuti nthumwi ankaona ali diuretic ndi zotumphukira venorasshiryayuschim kanthu amachepetsa m'mapapo mwanga mtima kukana, Sachita magazi mu makope m'mapapo mwanga ndipo zimachititsa kuti magazi kwa impso. Komanso, chiphunzitso kumathandiza thirakiti biliary ndi kubweza guluu wolimba kupatsidwa zinthu za m'mwazi ndi kutulutsidwa amkhalapakati a zochita hypersensitivity, ziziyenda mpanda wa maselo mlongoti, nthawi microcirculation, kuchepetsa chiopsezo cha thrombus mapangidwe ndi bwino mtendere wa erythrocytes.

Pa mlingo waukulu limasonyeza ankaona mankhwala katundu epileptogenic.

kinetics

magawo khalidwe la "theophylline" amatanthauza chiyani kayendedwe? Malangizo ntchito (slimming kukonzekera ichi ntchito nthawi zambiri) ikuti kuti pambuyo kulowa la munthu yogwira mchitidwe mankhwala ndi zimapukusidwa ndi wotsatira amasulidwe theophylline unbound, amene kenako chimamanga zonsezo plasma 40%.

Akuti kumatanthauza akhoza mkatikati mwa chotchinga placental, komanso linanena bungwe ndi mkaka mayi.

Transformation theophylline chimafikira mu chiwindi ndi puloteni cytochrome P450.

Mawonekedwe koyamba mankhwala ndi linanena bungwe mu kuchuluka kwa 10% mu mkodzo. Hafu ya moyo nthawi chida omwe sanali osuta, komanso odwala matenda a mphumu bronchial, ndi maola 12, ana - maola 1-5 mu ana akhanda - masiku 2, komanso osuta - maola 4.

Pamene kutumikiridwa?

Zikuonetsa ntchito mankhwala zimadalira mawonekedwe a zotsatira.

Dongosolo Parenteral akulimbikitsidwa:

• matenda ischemic wa kufalitsidwa oziziritsa;
• udindo asthmaticus ;
• anasiya yamitsempha yamagazi kulephera, amene anali kumva ndi mavuto kupuma, ndi bronchospasm;
• neonatal apnea;
• aakulu ndi pachimake kulephera mtima;
• edema chiyambi aimpso.

Nthawi zina, ntchito m'kamwa "theophylline" (mapiritsi)? Malangizo malipoti ntchito kuti chida amachita bwino mu mtima m'mapapo mwanga, broncho-obstructive matenda a etiology osiyana (mwachitsanzo, ndiko kumayambitsa chifuwa cha mphumu, COPD, obstructive matenda), matenda obanika kutulo, kuwonjezera kuthamanga mu makope m'mapapo mwanga, kulephera mtima ndi mtundu aakulu kapena wokonda .

contraindications

Pamene inu sayenera kugwiritsa ntchito mankhwala "theophylline"? Malangizo ntchito malipoti kuti contraindicated mu:

• aakulu wolumikizira hyper- kapena hypotension, tachyarrhythmia, zilonda za kapepala m'mimba, kuphatikizapo exacerbation ndi;
• giperatsidnom gastritis, mwaoneka aimpso kapena kwa chiwindi ntchito, hemorrhagic sitiroko, khunyu, kukha mwazi mu diso;
• munthawi yomweyo kugwiritsa ntchito ephedrine ana osakwana zaka zaka 3, kuchuluka kudziwa aminophylline kapena theophylline.

Mankhwala "theophylline": malangizo ntchito

Cellulite (ndemanga mtima ayankhidwa pansipa) ndi pothandizira wabwino, koma zimenezi si cholinga chachikulu cha mankhwala ankaona.

Kodi ine ntchito? Mlingo kamwedwe wa munthu medicament. Mankhwalawa anayamba ndi dokotala wodziwa malingana ndi chithunzi matenda, m'badwo wodwala, ndi pamaso pa umboni kudalira chikonga.

kukonzekera A mu mawonekedwe a njira angathe kuperekedwa intramuscularly kapena m'nsinga, komanso mafuta - ntchito kwa youma khungu nerazdrazhennuyu.

Monga ntchito kuwonda?

Kodi n'zotheka ntchito kuwonda mankhwala "theophylline"? Malangizo ntchito (a cellulite ndi chida kawirikawiri amagwiritsidwa ntchito mu mawonekedwe a mafuta ndi) lili chikutanthauza palibe uthenga. Komabe, akatswiri amanena kuti mankhwala yogwira mankhwala kwenikweni kumathandiza kuchepetsa thupi, komanso mwina kuchotsa "lalanje peel". Kodi zimenezi zimachitika? chakuti aminophylline akhoza kumapangitsanso magazi aziyenda bwino mu zimakhala ndi, komanso kusintha ngalande ntchito zawo. Chotero zinthu zopezeka zambiri creams chifukwa cellulite (mwachitsanzo, "Turboslim», Draine Minceur, Reflexe Minceur, Phyto-Complexe, Chojambula mmwamba , etc.).

Schematics wa ntchito mafuta ndi aminophylline zimadalira zikuchokera mokwanira ndi Mlengi.

zotsatira zoyipazi

Zotani mwachibadwa angachokere ntchito ndalamazo? Malinga ndi malangizo, zingayambitse:

• matenda tulo, nkhawa, chizungulire, khunyu ndipo kenaka utentha mamba;
• gastroesophageal Reflux, kusanza, kutsekula m'mimba, kunyansidwa, kutentha, anorexia, ndipo exacerbation la matenda chironda chachikulu;
• arrhythmias mtima, kupweteka mtima, aggravation wa pectoris angina, kuchepetsa kuthamanga, angina onyenga ndi tachycardia;
• hematuria, albuminuria;
• kuyabwa, malungo, ndi zotupa;
• hypoglycemia;
• ankatenthetsa, ululu ndi induration pa malo jekeseni;
• tachypnea, albuminuria, kupweteka m'chifuwa, hematuria, otentha kung'anima, hypoglycemia, thukuta ndi kuchuluka mkodzo tsiku.

Mogwirizana ndi ambiri osokoneza

Mpaka pano milandu akhala kudzera mwa uthenga deta ambiri osokoneza lipoti. Ngati vuto limeneli limapezeka, muyenera kusiya kumwa mankhwala ndi kuyamba mankhwala symptomatic.

Mu zikufanana kutenga mankhwala ndi sympathomimetics ndi kutsegula tonse zochita zawo pharmacological. Pankhani beta-blockers, ndi chuma lifiyamu, zotsatira za iwo matanthauzo wofooka.

The achire zotsatira "aminophylline" ndinasintha yafupika pamene ntchito imodzi ndi "pentobarbital", "rifamycins", "Isoniazid", "Carbamazepine", "sulfinpyrazone," "Phenytoin" (kuphatikizapo osuta).

Action ankaona mankhwala akhoza chinawonjezeka pamene co-kutumikiridwa ndi quinolones, "lincomycin" macrolides "cimetidine", "Allopurinol" isoprenaline, beta-blockers, fluvoxamine m'kamwa kulera, "Disulfiram", "Viloksazinom", komanso pa katemera fuluwenza .

Chelators ndi antidiarrheals kuchepetsa kumamatira "aminophylline."

Analogs ndi ndemanga ogula

Ngati pali analogs za "theophylline" mankhwala? Akatswiri kuyankha funso limeneli kuti inde. Ankaona mankhwala akhoza m'malo "aminophylline-esque", "Eufillin-Darnitsa", miyala ndi jakisoni "aminophylline".

Zimene anthu amanena zokhudza anati zikutanthauza ogula? Reviews kukonzekera kuti pali ndithu kwambiri. odwala ambiri inanena kuti jekeseni "aminophylline" ndi chida yasonyeza. nchito zake ndi dzuwa musati chifukwa kukayikira kulikonse, kuphatikizapo matenda a mphumu.

Koma ndemanga za "theophylline" kirimu ali maganizo. Ena ogula amati mankhwala izi ndi operewera. Komabe, pali odwala ena amene ndikugawa zotsatira chidwi kuthira mafuta a cellulite.