"Trimetazidine-Biocom MV": malangizo ntchito, zikuchokera, analogs ndi ndemanga

The medicament ali ndi zotsatira zomwe kuwawonetsera mofulumira njira kagayidwe kachakudya kunachitika ziwalo neurosensory ndi myocardium lapansi. Musanayambe chithandizo, muyenera kudziwa chimene chimapanga mankhwala "Trimetazidine-Biocom MV". Malangizo ntchito, zikuchokera mankhwala - kudziwa zomwe yankhoyi ifunika ku welenga.

Fomu kumasulidwa mankhwala, zigawo zake

Mankhwala limabweretsa kumasulidwa kusinthidwa zikutanthauza amachoka mu mawonekedwe a mapiritsi lokutidwa, opangidwa pamaziko a trimetazidine dihydrochloride. Chithuza lili mapiritsi 10 paketi kungakhale kuchokera 1 mpaka 6. piritsi imodzi lili 35 mg wa mbali yaikulu. Zikuchokera wodzilemekeza ndi magnesium stearate, povidone, aerosil, hypromellose ndi calcium wa hydrogen mankwala dihydrate.

Titaniyamu dioxide, Macrogol ndi yofunika chipolopolo piritsi "Trimetazidine Biocom-CF". Malangizo ntchito malipoti kuti kuwonjezera pa zinthu zimenezi chipolopolo tichipeza hypromellose ndi okusayidi wofiira chitsulo.

zotsatira pharmacological

Antihypoxanth chida amalola kuti abwezeretse kagayidwe yachibadwa maselo, zomwe zachitika chifukwa cha kusintha chowawa mu chitukuko ndi chikhalidwe cha pathological (ischemia, hypoxia). Mapiritsi akuletsa kuchepetsa kuchuluka kwa ATP maselo amathandiza kusintha kwa njira Kakhungu ion, transmembrane kayendedwe ka soda ndi potaziyamu ayoni. Akasamuka homeostasis ma mu nthawi ya matenda pogwiritsa ntchito medicament "Trimetazidine Biocom-CF". Malangizo ntchito inanena kuti mankhwala kuchepetsa mlingo pa zimene ndondomeko makutidwe ndi okosijeni zidulo mafuta, potero wamkulu shuga makutidwe ndi okosijeni imagwiridwa chitetezo m'mnyewa wamtima ndi ischemia. The kanthu za mankhwala zachokera kusintha ndondomeko makutidwe ndi okosijeni ndi zidulo mafuta ndi shuga.

Mankhwala, kukhala njira yachibadwa njira kagayidwe kachakudya, ndithu umakhudza ziwalo neurosensory ndi mitima, kuchepetsa zovuta kuyan'anila mu transmembrane otaya ion mu chitukuko cha ischemia. Timvere minofu mtima, mankhwala amachepetsa zizindikiro monga kusamuka, kusalola neutrophils polynuclear. Ponena za mmene mankhwala "Trimetazidine-Biocom MV" malangizo Buku zikuphatikizapo deta kuti kuimira ubwino myocardium wakhala kuonongeka ndi ischemia. Hemodynamic mankhwala ali mwamtheradi chikoka.

Pharmacokinetics

Mayamwidwe chikuchitika pafupifupi mwathunthu ndipo mwamsanga. Kulankhulana ndi mapuloteni plasma yochepa (16%), mlingo wa bioavailability ndi 90%. Ndi kukhazikitsidwa kwa miyala mpaka nthawi imene mlingo wa mankhwala yogwira m'thupi chimakhala pazipita, izo chimafikira pafupifupi maola awiri. Amadziwika kuti mankhwala akudutsa mosavuta kudzera zotchinga magazi minofu. Theka moyo ikuchitika maola pafupifupi asanu. The mankhwala ndi thupi chikutha ndi impsozo, ambiri a iwo sasintha mawonekedwe ake.

umboni

"Trimetazidine Biocom-CF" (mapiritsi) malangizo angagwiritsidwe ntchito kukhazikitsa yaitali CHD chithandizo. cholinga chake zikusonyezedwa milandu zotsatirazi:

• kufunika kukhazikitsa njira zodzitetezera ngati yatsoka kuukira angina;
• chizungulire, pamaso pa zomwe zimagwiritsa zotupa mtima;
• matenda cochle-vestibular ndi chikhalidwe ischemic (kuwonongeka kumva);
• matenda chorioretinal mtima, limodzi ndi ischemia.

angina prophylaxis angathe kuchitidwa ntchito mankhwala umodzi kapena ndikukhazikitsa mankhwala zovuta.

contraindications

Ponena za nthawi imene osafunika kumwa mankhwala "Trimetazidine-Biocom MV" malangizo Buku, ndemanga muli deta zikusonyeza kuti n'zosatheka mankhwala mankhwala limati awa:

• tilinazo kwambiri kwa chigawo chimodzi ndi zinthu zina zazikulu njira;
• Kuyamwitsa;
• pa kubala ana.

Popeza chitetezo cha ntchito mankhwala ana (pasanathe zaka 18) ndi mphamvu ya mankhwala ndi ntchito zake osati zakhazikitsidwa, odwala ngati izi zikutanthauza si yoikidwiratu.

Mankhwala contraindicated ndi anasonyeza chiwindi anthu olephera impso, amene chizindikiro monga creatinine chilolezo ali kwambiri yafupika (ndi 15 ml / mphindi kapena zochepa). Osati kudziwa zizindikiro ndi contraindications mankhwala ndi kuthekera "Trimetazidine-Biocom MV". Mtengo alinso ena kufunika posankha medicament kwa mankhwala. Pa nkhani zotsatirazi.

mankhwala

kukula limodzi mlingo anatsimikiza ndi dokotala (zambiri osachepera 40 mg wa koma osapitirira 60). Mu maola 2-3 chofunika kuchita kuti alandire njira. Nthawi mankhwala udzakhazikitsidwe padera kwa nthawi zosiyanasiyana.

zotsatira zoyipazi

Pamaso mankhwala, m'pofunika kuti ayanjane ndi zotheka zosiyanasiyana chokhwima pambuyo ingestion miyala chamoyo "Trimetazidine Biocom-CF". Malangizo ntchito njira, potengera zomwe mankhwala ndi mavuto monga ziwengo, kuwonetseredwa monga kuyabwa ndi ziwengo, zochita zina zimene zachilendo kwa thupi. Pa mankhwala, mu nthawi zina kwambiri, ena odwala ndi nseru, kusanza zachitika, amatchuka gastralgia.

Nthawi cha mankhwala osokoneza bongo aakulu sizinachitike mapulani ndi kuthekera asayembekezere ndi chodziwikiratu. Chifukwa cha choposa mlingo zingaoneke ankatenthetsa nkhope, hypotension.

Kusamala

Mankhwalawa sakhala akuletsa kuthekera kuyendetsa ndi sikusokoneza kuchita zinthu mu ntchito za chimene chimafuna mofulumira thupi ndi psychomotor zosiyanasiyana.

Mapiritsi sali oyenera kuwonongedwa kuukira angina ndipo angagwiritsidwe ntchito kokha zolinga njira ndi odwala amene amadwala zoopsa zotere.

Mankhwala a odwala matenda a mitima ndi kuchepa chofunika tsiku la ku feteleza.

Mtengo wa analogues mankhwala, ndemanga

Izo ziyenera anaphunzira kale chithandizo amatanthauza "Trimetazidine" malangizo Buku. Price komanso mauthenga yofunika ndiponso kuganizira posankha mankhwala kuchipatalako (prophylaxis), matenda a mtima (inatsekeratu mtsempha wamagazi matenda). The ndalama pafupifupi mankhwala ndi 100-165 rubles. mapiritsi 30 189-208 rubles. mapiritsi 60.

The analogue angagwiritsidwe ntchito "Preductal", "Antistius" kapena "Trimethyl". N'zotheka mankhwala osokoneza bongo "Medarum", "Rimekor". adokotala akhoza m'malo mankhwala mwa kusankha "Prekard", "Angiozyme", "Trimitard MV". Pali kuthekera amachitira "Tridukardom", "Predizinom", "Trimektalom" kapena "Metagardom". Tikayang'ana ndemanga, ndi analogue wotchuka ndi "Preductal" Izi mankhwala othandiza, koma ndi okwera mtengo kusiyana "Trimetazidine". Malangizo ntchito, mtengo limasonyeza kuti mankhwala n'kopindulitsa, ndemanga atsimikizire efficacy mankhwala izi.

Mu ndemanga ya medicament ya Akuti mankhwala ndi bwino kumatha ululu mu mtima, iwo amachita ntchito yake mwangwiro. Chifukwa mlingo monga odwala ndi madokotala, amalembedwa anasinthira, mwachitsanzo, thupi la anthu akulandira mankhwala bwino kuzindikira thupi. Anthu ambiri amanena kuti patapita masiku angapo mankhwala anataya dyspnea, tachycardia chikuchitika, kuthamanga kwa magazi kubwerera mwakale. Kawirikawiri amalembedwa kusintha pa tsiku lachinayi la mankhwala, zochokera ntchito panopa ndalama "Trimetazidine-Biocom MV". Malangizo ntchito, mtengo limasonyeza kuti mankhwala chilipo komanso aluso, kuwonjezera, ali ndi mlingo wa zotheka zosiyanasiyana chokhwima kuti nthaŵi zambiri kukhala. Zikamera mavuto anamuona pa nthawi zina.

Choncho, takupatsani mudziwe zambiri za mankhwala "Trimetazidine-Biocom MV". Analogues, mtengo, kutsogolera ndemanga za mankhwala inu tsopano kudziwika. Mankhwala adzasankhidwa akatswiri ntchito akhalemo mlingo. Kufunika m'malo a medicament monga anatsimikiza mtima dokotala zochokera zifukwa zambiri. The malangizo amalola kuti mankhwala ambiri popanda choipa.