An matenda autoimmune ndi thrombocytopenic purpura

Kwa nthawi yoyamba ndi autoimmune thrombocytopenic purpura, limafotokonzera cha 1735 Verlgofa amene anaona matendawa mtsikana zaka khumi. Pano fomu iyi dzina ophatikizana autoimmune thrombocytopenia, chifukwa autoaggression pa zomwe zikutha. Iwo amaoneka hemorrhagic diathesis ndi akusowa wakutali wa othandiza magazi kuundana. Kuonetsetsa pachimake ndi aakulu mawonekedwe a matenda.

zimayambitsa

Pachimake thrombocytopenic purpura zowawa makamaka ana zaka 2 mpaka 9. Thrombocytopenic purpura ana amakhala ndi isanayambike mwadzidzidzi kuchira mwamsanga. Development maonekedwe matenda limalimbikitsa tizilombo wa chapamwamba kupuma thirakiti kapena kapepala m'mimba. 10% ya milandu matenda kugwirizana ndi kukula varicella HIV, Epstein-Barr HIV, Katemera, BCG immunotherapy. chiwonongeko kupatsidwa zinthu za m'mwazi chifukwa yankho m'thupi la chamoyo osati kanthu za HIV.

mitundu aakulu a thrombocytopenia chosatha miyezi yoposa 6 amatchedwa idiopathic thrombocytopenic purpura. Chifukwa cha matenda ndi losadziwika. Thrombocytopenic purpura zambiri kumayambira unyamata, unamwali. More zofala akazi.

Matenda mawonetseredwe kuonekera pang'onopang'ono. Yodziwika ndi aakulu-chosatha kapena yaitali Inde matendawa. Pathogenetic chifukwa cha matenda chimawonjezeka ndipo inapita kupatsidwa zinthu za m'mwazi kuwonongedwa ndi autoantibodies ndi iwo.

chithunzi matenda

Pa khungu la odwala ndi zizindikiro za microcirculatory magazi mtundu ngati punctate petechial totupa yaing'ono subcutaneous hematoma, purpura pa mucosa m'kamwa. Yodziwika ndi magazi a nembanemba mucous mphuno, m'kamwa. Kusintha kwa khungu zambiri ili kutsogolo padziko malekezero thunthu, chapamwamba ndipo m'munsi. Childs mapangidwe kukha mwazi lalikulu pa malo jekeseni. Nthawi zina pangakhale magazi mu sclera ndi diso, magazi kuchokera thirakiti m'mimba. Mu akazi, pali kukha magazi ambiri m'mimba lapansi. M'njira choopsa cha magazi matenda aimpso angagwe.

purpura Thrombocytopenic kungachititse kuti mavuto oopsa monga kukha mwazi kwa muubongo ndi subarachnoid kukha magazi. Khalidwe ndi zabwino khafu mayesero Konchalovsky wolima-LEED: mapangidwe kukha magazi m'madera khungu la psinjika. Lymph mfundo, chiwindi ndi ndulu ayi wakulitsidwa.

diagnostics

Mbali yaikulu ya zasayansi ndi kuchepetsa chiwerengero cha othandiza magazi kuundana. magazi clotting nthawi sanaphwanye. Heparin plasma wakhala kuchuluka. Nthawi zambiri, kutsimikiza ndi kuwonjezeka wa immunoglobulin G othandiza magazi kuundana. Pambuyo magazi kwambiri kumatanthauza pachimake hemorrhagic magazi m'thupi.

chithandizo

Ngati anapezeka ndi thrombocytopenic purpura, odwala ayamba mankhwala ndi corticosteroids. Pa mankhwala, odwala anaona Kuwonjezeka kupatsidwa zinthu za m'mwazi, ayesere mpaka chikhululukiro wathunthu. Kusowa kwa mphamvu ya corticosteroids ndi immunomodulators Kwalamulidwa delagil. Ndi kupanda mankhwala ndiwofatsa mkati miyezi 6 amalangiza kuchita splenectomy.

Wina kudera la mankhwala - ka mlingo waukulu wa immunoglobulin kwa mtsempha jekeseni kwa masiku 5. Kukonzekera izi inactivate chitetezo kuti kumumanga ndi kuchotsa tizilombo toyambitsa ndi zina antigens.

Mu 80-90% ya odwala ayambe mowiriza amapezeka mkati miyezi 1-4. Nthawi zina, thrombocytopenic purpura ukhoza kwa miyezi 12. Matendawa akudwala relapsing: magazi nthawi ina ndi nthawi ya chikhululukiro.