Piritsi "Silhouette": ndemanga madokotala, malangizo Buku. Mankhwala olerela ndi "Silhouette": ndemanga za endometriosis

Masiku ano, mkazi ali ndi ufulu wokonzekera mimba yake. Izi zikhoza kuchitika m'njira zingapo, koma imodzi mwa njira yabwino kwambiri komanso yothandiza ndi kulandira chithandizo cham'thupi.

Njira yoyamba yodzitetezera mimba m'mapiritsi anali ndi gawo lalikulu la mankhwala ogwira ntchito ndipo mosakayikira linayambitsa zotsatirapo, monga kulemera. Njira zamakono zamakono za kulera zimasiyana mosiyana ndi momwe mlingo wa chogwiritsira ntchito mwa iwo uli wosayenerera. Izi zimathandiza mkazi kuti azikhala wolemera. Komanso, njira zothandizira kulera za m'badwo watsopano zitha kusintha kwambiri chikhalidwe cha khungu ndi tsitsi, kuthetseratu kutupa pang'ono pa nthawi ya kusamba.

Imodzi mwa njira zamakono zopezera mimba yosafunika ndi piritsi "Silhouette." Kufufuza za chida ichi chingapezeke mosiyana. Tiyeni tiwone bwinobwino mbali za mankhwalawa.

Ngati tiganiziranso mankhwalawa kuti tigwire ntchito ku chipatala, ndiye kuti ndi njira yokha yothandizira kulandira mankhwala omwe ali ndi antiandrogenic yomwe imapangidwira kuti azitha kulumikiza.

Kodi zimapangidwa m'njira yotani?

Mapiritsi oletsa kubadwa "Silhouette", ndemanga zowonjezera zabwino, zowoneka zoyera, mawonekedwe ozungulira biconvex ndikulemba "G53" mbali imodzi. Chinyezicho chili ndi zidutswa 21.

Maonekedwe a kukonzekera

Pulogalamu imodzi ili ndi zowonjezera izi:

• Ethinylestradiol mu kuchuluka kwa 30 μg.
• Dienogest mu ndondomeko ya 2 μg.

Zomwe zimapangidwanso pali zothandizira: lactose monohydrate, starch corn, hypromellose, talc, potassium polyarylate ndi magnesium stearate.

Kodi mankhwalawa amagwira ntchito bwanji?

Pulogalamu "Silhouette", ndemanga zomwe zimalongosola za kuvomerezedwa kwa atsikana, ndizophatikizidwa pamodzi ndi mankhwala otchedwa antiandrogenic. M'mawonekedwe ake muli mahomoni ethinyl estradiol, omwe amachititsa ntchito ya estrogen ndi dienogest, yomwe ndi progestogen. Kulera uku kumachita ntchito zotsatirazi mu thupi la mkazi:

• Amaletsa ovulation.
• Kuwonjezeka kwa mamasukidwe akayendedwe a kondomu.
• Kusintha zowonongeka za ziphuphu zakufa.
• Amatembenuza dongosolo la endometrium.

Zopangira ziwirizikulu zokhudzana ndi wina ndi mzake zimakhudza kuchepetsa androgens mu plasma.

Kwa amayi ambiri, piritsi la "Silhouette" (umboniwu ndi chitsimikizo) imathandiza kuthana ndi vuto la ziphuphu zochepa, komanso seborrhea.

Dienogest ya hormone imachokera ku norethisterone. Ndizowonjezera kasanu ndi kawiri kuposa zovomerezeka za progesterone kusiyana ndi zinthu zina zogwirizana ndi gulu lino. Zochitika za dienogest ndizoti sizinatchule kuti androgenic, glucocorticoid ndi mineralocorticoid. Kugwiritsira ntchito moyenera ma hormone pa mlingo wa 1 mg pa tsiku kumachepetsa kuchepa kwa ovulation.

Kodi pharmacokinetics ndi chiyani?

Monga tanenera poyamba, piritsi "Silhouette", ndemanga zomwe zimayankhula za kutchuka kwake, zili ndi zinthu ziwiri zomwe zimakhala zosiyana m'thupi la munthu.

Ethinyl estradiol ikalowetsedwa m'kati mwa katumbo kamene imathamanga kwambiri ndipo imatha kufika pamtunda waukulu pambuyo pa maola 1.5-4. Chiwerengero chachikulu cha mankhwalawa ndi chiwindi ndi chiwindi. Mtheradi wa bioavailability wa ethinylestradiol ndi 44%. Zinthu izi zimaphatikiza 98% kuti zizikhala m'magazi a magazi, zimawonjezera globulin. Mapuloteniwa amamanga mahomoni ogonana. Mu theka lachiwiri la kumwa mankhwalawa, chiwerengero chokwanira cha ethinyl estradiol chimadziwika.

Zinthuzi zimagwiritsidwa ntchito m'matumbo mumkati komanso m'chiwindi kudzera mu zonunkhira za hydroxylation ndi zowonjezera zambiri. Zotsatira za kuwonongeka kwa chiwindi ndi impso zimachotsedwa mu magawo awiri:

• Yoyamba ndi ora limodzi.
• Nthawi yachiwiri ndi maola 10-20.

Ethinyl estradiol yosasinthika kuchokera ku thupi laumunthu sichidaperekedwa.

Dienogest imathandizidwanso m'magazi kudzera pakhoma la m'mimba ndipo imatha kufika pafupipafupi pambuyo pa maola 2.5 kuchokera nthawi yobereka. Chidziwitso chake ndi ethinyl estradiol ndi 96%. Dienogest imangomangirira albins okha. Kufanana kwake pamtundu waukulu wa plasma ndondomeko ikupezeka mu masiku 4 mutenga mankhwala.

Dienogest imasinthidwa ndi hydroxylation ndi glucuronization. Zogulitsidwa za kugawanika kumeneku sizingatheke ndipo mwamsanga zimasiya magazi a m'magazi.

Dienogest pangТono kakang'ono mwa mawonekedwe osasinthidwa amawasokoneza ndi impso. Mukamadya 0,1 mg / makilogalamu a mankhwalawa, pafupifupi 86% amafufuzidwa m'masiku 6 oyambirira ndi matumbo ndi impso, ndipo pafupifupi 42% ya mankhwalawa amachotsedwa m'maola 24 oyambirira ndi mkodzo.

Kodi ndiyenera kutenga chiyani?

Piritsi "Silhouette", ndemanga za zomwe ziri zabwino, ziyenera kutengedwa tsiku ndi tsiku komanso panthawi inayake. Ngati ndi kotheka, mukhoza kumwa madzi pang'ono. Onetsetsani kutsatira ndondomeko yomwe yawonetsedwa pa phukusi.

Chitsogozo chachikulu kuti mutenge "Silhouette" (mapiritsi) - malangizo. Ndemanga zokhudzana ndi chithandizochi zimatsimikizira kuti kupezeka kwa njira yogwiritsiridwa ntchito kwake mu ndondomekoyi. Zimasonyeza chiwembu malinga ndi zomwe piritsi limodzi la mankhwala limatengedwa kamodzi pa tsiku kwa masiku 21. Ndiye kupuma kwa masiku asanu ndi awiri kumachitika musanayambe phukusi latsopano ndi mankhwala. Panthawi imeneyi, pali "kuchotsa magazi". Kawirikawiri izi zimayamba masiku awiri pambuyo pa mapiritsi omaliza ndipo amatha masiku 4-5. Panthawiyi, palifunika kutenga mapiritsi kuchokera kumsana watsopano.

Pali nuance yofunika kwambiri yomwe imayambira kulandira mapepala "Silhouette." Malangizo ogwiritsiridwa ntchito (madokotala a umboni kuti atsimikizire izi) amasonyeza kufunika kokhala ndi chithandizo pa tsiku loyamba la kusamba. Matendawa ndi oyenerera kwa omwe kale sanagwiritse ntchito mankhwala opatsirana pogonana kapena sanagwiritse ntchito mankhwalawa kwa mwezi kapena kuposerapo.

Mbali za kulandira chithandizo

Ngati pangakhale kusinthika kuchokera ku chithandizo cholumikizira palimodzi ku piritsi, Chidziwitso cha dokotala chimalimbikitsa kuti mankhwalawa atenge nthawi yotsatira pambuyo pake.

Ngati pangakhale kusowa kosintha kuchokera ku njira za kulera zokha zomwe zili ndi progesterone yokha, ndiye kuti izi zikhoza kuchitika tsiku lililonse. Ngati wodwala atachotsa chophimbacho, mwachitsanzo, chikhomo, ndiye tsiku lomwelo akhoza kutenga Silhouette. Mayiyo atatenga njira yolerayo ndikuganiza kuti amasintha ku mapiritsi omwe ali ndi kachilombo koyambitsa matendawa, mlingo woyambirira ayenera kutenga nthawi yomwe adakonzekera kuwombera.

Ngati mayi ali ndi pathupi pa 1 trimester ya mimba, ndipo akukonza kutenga mankhwala a hormone a Silhouette, malangizo, umboni ndi ndondomeko za madokotala zimasonyeza kuti angathe kugwiritsa ntchito mankhwalawa mwamsanga. Ngati kuchotsa mimba kumachitika tsiku lotsatira, ndiye kuti pakufunika kuimitsa masiku 21-28 ndikugwiritsa ntchito kondomu nthawiyi.

Kodi ndiyenera kuchita chiyani ngati sindinapite kumwa mapiritsi?

Zikakhala kuti kuchedwa kwa phwando sikudutsa maola 12, mphamvu ya kulera sikuchepetse. Mayiyo agwiritsire ntchito mapiritsi mwamsanga, ndipo kumwa moyenera kumakhala nthawi yeniyeni.

Zikakhala kuti kuchedwa kunapanga nthawi yayitali kuposa maola 12, m'pofunika kuchita mogwirizana ndi malamulo ofunika kutenga chithandizo:

• Simungathe kusokoneza kugwiritsa ntchito ndalama zoposa sabata.
• Kuti mankhwalawa agwire ntchito, mukufunikira osachepera masiku asanu ndi awiri a msonkhano wowonjezera.

Choncho, madokotala amapereka malangizo otsatirawa:

• Ngati pulogalamuyo ikadakalandiridwa sabata yoyamba yogwiritsiridwa ntchito kwa mankhwalawa, ndiye kuti mayiyo ayenera kumwa piritsi nthawi yomweyo, ndi ntchito yotsatira nthawi yeniyeni. Pa nthawi yomweyo, muyenera kugwiritsa ntchito kondomu mlungu wotsatira.
• Ngati izi zitachitika m'nthawi yachisanu ndi chiwiri, pempherani piritsi, ndipo njira zolepheretsa kubereka siziyenera.
• Mu sabata lachitatu, kulephera kutenga mankhwalawa kumafuna dongosolo lofotokozedwa m'ndime yoyamba. Pambuyo pake, pita kumtsinje wotsatira popanda kusokonezeka. Pankhaniyi, "kuchotsa magazi" sikungakhalepo.

Mukhozanso kuchepetsa kuyamba kwa magazi ndi pilisi Silhouette. Ndemanga za madokotala pankhaniyi ndikulimbikitsidwa pakadali pano kuti mupitirize kumwa mankhwalawa, m'malo mwake mutengere mankhwalawa. Pogwiritsira ntchito phukusi lachiwiri la mankhwala, mayi akhoza kusindikiza katemera wake wa uterine.

Kodi kudutsa kwina kungatheke?

Kuopsa kwa kuchuluka kwa mahomoni omwe amapanga miyala ya Silhouette ndi yotsika. Ngati kudyetsa, kunyoza, kusanza, kukhuta kwa amayi kapena kutuluka magazi kumadziwika. Palibe chifukwa cha mankhwala.

Kodi "Silhouette" ingatengedwe ndi mankhwala ena?

Zinanenedwa kuti kudyetsa pamodzi ndi mankhwala omwe amachititsa michere microsomal, kungachititse kuti magazi awonongeke komanso kuchepetsa kuchepetsa kulera. Mankhwalawa ndi Phenobarbital, Rafampicin, Hydantoin, Primidon, Carbamazepine, Rifabutin, Efavirenz, Nevirapine, Oxycarbazepine, Felbamate, Griseofulvin, Topiramate "," Ritonavir "komanso kuyerekezera kwa mankhwala a St. John's wort zonunkhira.

Kudyetsa ma antibayotiki ena, monga tetracycline kapena ampicillin, mogwirizana ndi Silhouette amachepetsanso mphamvu zake. Pankhani yothandizira ndi mankhwala ena alionsewa, palifunika kwina kutetezedwa kwa masiku 7, ndi "Rifampicin" - masiku 28.

Ndi zotsatira zotani za mankhwalawa?

Simungasankhe nokha kusankha njira iyi. Kumbukirani kuti "Silhouette" - mapiritsi a hormone. Malingaliro a madokotala okhudza zotsatirapo za kulera uku amatsimikizira kuti imalimbikitsa kupanga ma thrombi mu mitsempha ndi mitsempha. Chodabwitsa chimenechi chikhoza kuwonjezeka ndi kusuta, kuthamanga kwa magazi, kuphwanya magazi, mitsempha ya varicose, kunenepa kwambiri, thrombosis ndi thrombophlebitis.

Zina mwa zotsatira zoyipa zimatchulidwanso kuti:

• Migraine.
• Nsowa ndi kusanza.
• Kulemera kwa thupi;
• Zomwe zimapweteka kwambiri m'mimba ya mammary ndi kukulitsa kwawo;
• Kusasinthasintha mtima;
• Ululu kumbuyo;
• Kuphwanya mu minofu ya ana a ng'ombe.

Amayi ambiri amakana kugwiritsa ntchito njira zothandizira pakamwa pamalopo chifukwa choopa kukhala bwino. Kodi mantha awa ndi olondola? Chimodzi mwa zinthu zofunikira zowunikira ngati ndizotheka kulemera kuchokera kulandira "Silhouette" mapiritsi ndi ndemanga. Kuwonjezeka kwa kulemera kwa thupi kumadziwika chifukwa cha amayi ambiri. Ndicho chifukwa chake zotsatira za kutenga chithandizochi ndizofala kwambiri.

Zotsatira zovuta zotsatirazi pogwiritsira ntchito kukonzekera "Silhouette" zimasiyana mozungulira maulendo apakati pa odwala:

• Matenda osokoneza bongo kapena kuthamanga kwa magazi.
• Thrombophlebitis ndi mitsempha ya varicose.
• Migraines ndi chizungulire.
• Kuwonjezeka kwakukulu.
• Ululu m'mimba.
• Matenda opatsirana a mavitamini.
• Acne, exanthema, odwala ndi acneiform dermatitis, allopecia, erythema, pruritus, chloasma.
• Kuwonjezeka kwa kudya kapena kulemera kwa thupi.
• Vaginal candidiasis, vaginitis.
• Kutopa, malungo, kudzikuza.
• Acyclic ndi magazi owawa, endometrial hyperplasia, endometritis, salpingitis.

Palinso zina, koma zochepa zomwe zimakhalapo chifukwa chotenga mapiritsi a "Silhouette". Malangizo ogwiritsidwa ntchito, ndemanga za odwala ndi madokotala amasonyeza mawonetseredwe otsatirawa:

• Anemia.
• Matenda a mtima.
• Kusokonezeka kwa magazi m'magazi.
• Matenda owonetsa.
• Sinusitis, bronchitis, mphumu.
• Matenda a m'mimba.
• Kuthamanga, chizungu, seborrhea, angioedema.
• Kuchepetsa kudya.
• Zovuta.
• Kutuluka kwa mimba, kusintha ndi matumbo a mammary gland, leiomyoma.
• Kusagona, kudandaula.
• Arthralgia, myalgia.

Palinso zotsatira zochepa zomwe zingatheke chifukwa cha kumwa mankhwalawa. Mapiritsi, umboni wotsimikiziridwa uwu umatsimikizira, ndifupipafupi zosakwana 1 peresenti ya 10,000 amatha kuyambitsa matenda a myocardial inforction, gallstones, cholecystitis ndi khansa ya endometrial.

Contraindications

Mankhwalawa "Silhouette" sangathe kutengedwa pamaso pa matenda ena. Izi ndi izi:

• Matenda a mitsempha ndi mitsempha, kuteteza thrombosis.
• Pancreatitis.
• Porphyria.
• Jaundice kapena congenital syndromes ya hyperbilirubinemia.
• Kusuta pambuyo pa zaka 35.
• Kuwonongeka kwa chiwindi, kuphatikizapo khansara.
• Kuchepetsa magazi m'magazi osadziwika.
• Migraines.
• Khunyu.
• Matenda a m'magazi.
• Mimba ndi lactation.
• Kusagwirizana kwa Lactase.
• Kutsekula kwa zigawo zikuluzikulu za mankhwala.

Pa matenda aliwonsewa, "Silhouette" yachitsulo imatsutsana.

Kuchiza kwa endometriosis

Endometriosis ndi matenda omwe ndi ofala kwambiri kwa amayi. Amachiritsidwa ndi njira zowonongeka kapena zopaleshoni, malingana ndi momwe matendawa aliri. "Silhouette" (mapiritsi) ndemanga mu endometriosis zakhala zabwino. Mankhwalawa nthawi zambiri amatumizidwa kwa odwala, monga momwe amachitira ndi "Jeanine". Momwemonso akatswiri a matenda a amai amasonyeza kuti ali ndi chitetezo chokwanira komanso bwino.

"Silhouette" imachititsa kuti atrophy apang'onopang'ono za epometriosis, mosasamala kumene ali. Zimachepetsa kaphatikizidwe ka mayendedwe a estrogens, amachititsa kuti chivundikiro chikhale chochepa komanso chimachepetsa kuchuluka kwa maselo a minofu kunja kwa chiberekero cha uterine. Palinso mankhwala abwino otsutsa-kutupa pogwiritsa ntchito mankhwala "Silhouette". Maphunziro a mapiritsi ndi endometriosis ali ndi vuto - amai amazindikira kuwonongeka kwa zizindikiro za kuchepa kwa magazi, mapuloteni ndi chikondi mu kugonana.

Kuwonjezera pamenepo, zigawo zikuluzikulu za mankhwalawa "Silhouette" amachepetsa magazi ku foometryosis. Zotsatira zake, minofuyi imasiya kukula. Mpweya wabwino wa hemoglobini umabwezeretsedwa.

Tiyeneranso kukumbukiranso kuti kugwiritsira ntchito mankhwalawa kulimbikitsidwa kokha ndi dokotala atapenda mokwanira wodwalayo chifukwa cha kukhalapo kwa matenda ndi mayiko akale. Kugwiritsidwa ntchito kosagwiritsidwa ntchito kwa mahomoni opatsirana pogwiritsa ntchito mahomoni kumawopsya ndi zotsatira zosafunikira za thupi.