Chitetezo kwa TPO chitetezo

Pakali pano, vuto lonse la chithokomiro England sasiya kufunika kwake. Kupanda ayodini m'thupi zimawonedwa 40% ya akulu ndi ana 50%. Ichi ndi chifukwa osati chinthu cholowa, komanso chikoka zoipa za chilengedwe. Pankhaniyi, ayodini zochita kupanga kwa kaphatikizidwe mahomoni monga T3 ndi T4, amene amadalira chiwerengero cha pituitary chithokomiro zolimbikitsa timadzi (TSH), chithokomiro kulamulira zochitika.

Izo ziyenera kuti ngati mabele England si mokwanira kukwaniritsa ntchito zake, matenda ena (autoimmune) kukhala mu thupi. Choncho, kudziwika kuphunzira AT TPO chitetezo zingasonyeze ndi maudindo aukali mthupi ndi ulemu kwa thupi. N'chifukwa chake mitundu yosiyanasiyana ya matenda a chithokomiro akapatsidwa kuphunzira mlingo magazi TSH ndi kukhalapo kwa chitetezo ku AT TPO. Ngati iwowa ndi chikusungidwabe, ndiye mmodzi ayankhula matenda ndi autoimmune.

AT TPO zimatanthauza enzyme nawo kaphatikizidwe mahomoni ndi SHCHZ pa mahomoni iodization. Iye ndi membala tireyodnogo Antigen.

Chifukwa kusanthula atha kutumikira ngati matenda a matenda monga Chotupa chija, hypo- ndi hyperthyroidism, matenda manda, tireoinid drumsticks edema. Komanso, kuwunika Kwalamulidwa pa mimba kudziwa chiopsezo tireoinita akabereka (10% ya amayi ndi matenda).

Tikumbukenso kuti TPO chitetezo, mlingo pa zomwe wamkulu ndi 5.6 U / ml, mu thupi lili yogwira ayodini mapangidwe. Chitetezo ku puloteni imeneyi kumathandiza ntchito yake, kotero amachepetsa katulutsidwe mahomoni T4 ndi T3. Koma si milandu onse, chithokomiro peroxidase akusonyeza pamaso pa ndondomeko autoimmune.

Phunziro ili yofunika kwambiri kwa matenda a matenda a chithokomiro. Maonekedwe a kuyan'anila mu ntchito yake ndi chizindikiro cha hypothyroidism. Pamene ntchito njira tcheru kwambiri diagnostikiAT TPO, ndiye matenda amene amapezeka 94% ya odwala matenda manda '- 84%, matenda a chithokomiro neautoimunnye - 15% ya anthu. pamlingo wochepa wa enzyme ndi amapezeka anthu athanzi, choncho ichi funso la chitukuko cha matenda osiyanasiyana ndi bwino anamvetsa.

Tikumbukenso kuti mu nkhani kumene AT TPO kuchuluka, amenewa amasonyeza ndondomeko monga hypothyroidism. Mtundu uwu wa kuphwanya zikuoneka chifukwa cha deceleration oteteza TPO ntchito, mlingo makutidwe ndi okosijeni ayodini, choncho chikhazikitso cha mawonekedwe ake yogwira. Pankhaniyi, mahomoni mabele si apanga.

phunziro udzadutsa magawo angapo. Anthu, magazi amatengedwa, chimene mlingo wofunitsitsa TSH ndi T4. Pankhani ya T4 ntchito zachilendo ndipo otsika TSH, ikuchitika kuphunzira T3. Zikatero, muyenera kumaliza kafukufuku pa AT TPO chitetezo.

Choncho zikuonetsa kuti kuphunzira atha kutumikira ngati amaganiziridwa Chotupa chija, hypothyroidism ndi thyroiditis Hashimoto a. Koma tiyenera kukumbukira kuti kusapezeka kwa chitetezo kwa chithokomiro peroxidase ait si akuletsa kwake mu thupi. Kupezeka kwa enzyme izi magazi sapereka sakukayika pamaso pa matenda ndi autoimmune, kuyambira nthawi zambiri pa TPO chili mwa anthu mwinamwake wathanzi.

Kuyambira zonsezi ndizoonekeratu kuti kudziwika enzyme izi ndi zofunika kuti achite kafukufuku mabuku ndi cholinga kuthetsa kufala kwa ait.

Motero, kaya zinthu, chithokomiro peroxidase ndi mokwanira tcheru kuvutika mayeso autoimmune mu chithokomiro Komabe, kafukufuku ntchito iliyonse bungwe pafupifupi zachipatala.